The Experts below are selected from a list of 5352 Experts worldwide ranked by ideXlab platform
Fan Yang - One of the best experts on this subject based on the ideXlab platform.
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neutron induced radiation damage in lyso baf 2 and pwo crystals
2020Co-Authors: Fan Yang, Michael Mocko, Jon Kapustinsky, Liyuan Zhang, R Y Zhu, R O Nelson, Zhehui WangAbstract:One crucial issue for the application of scintillation crystals in future high-energy physics experiments is radiation damage in a severe radiation environment, such as the high luminosity large hadron collider. While radiation damage induced by ionization dose in inorganic scintillators is well understood, investigations are ongoing to understand radiation damage induced by hadrons, including both charged hadrons and neutrons. Aiming at understanding neutron-induced radiation damage in fast inorganic scintillators, Lutetium yttrium oxyorthosilicate (LYSO)/Lutetium fine silicate (LFS), BaF2, and PWO crystals were irradiated at Los Alamos Neutron Science Center by a combination of particles, including neutrons, protons, and $\gamma $ -rays. The results indicate that LYSO/LFS and BaF2 crystal plates are radiation hard up to a 1-MeV equivalent neutrons fluence of $9 \times 10^{15}$ equivalent neutron (neq)/cm2, but not PWO, and the neutron-induced radiation damage in LYSO crystals is a factor of ten less than protons.
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Neutron-Induced Radiation Damage in LYSO, BaF2, and PWO Crystals
2020Co-Authors: Chen Hu, Michael Mocko, Jon Kapustinsky, Ron Nelson, Liyuan Zhang, Fan Yang, Zhehui WangAbstract:One crucial issue for the application of scintillation crystals in future high-energy physics experiments is radiation damage in a severe radiation environment, such as the high luminosity large hadron collider. While radiation damage induced by ionization dose in inorganic scintillators is well understood, investigations are ongoing to understand radiation damage induced by hadrons, including both charged hadrons and neutrons. Aiming at understanding neutron-induced radiation damage in fast inorganic scintillators, Lutetium yttrium oxyorthosilicate (LYSO)/Lutetium fine silicate (LFS), BaF2, and PWO crystals were irradiated at Los Alamos Neutron Science Center by a combination of particles, including neutrons, protons, and γ-rays. The results indicate that LYSO/LFS and BaF2 crystal plates are radiation hard up to a 1-MeV equivalent neutrons fluence of 9 × 1015 equivalent neutron (neq)/cm2, but not PWO, and the neutron-induced radiation damage in LYSO crystals is a factor of ten less than protons.
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the influence of sc lu ratio on the phase transformation and luminescence of cerium doped Lutetium scandium orthoborate solid solutions
2011Co-Authors: Yuntao Wu, Dongzhou Ding, Fan YangAbstract:Abstract The dependence of structural characteristics of cerium-doped Lutetium scandium orthoborate (Lu1−xScx)BO3:Ce solid solutions on Sc/Lu ratio was investigated. It was found that the calcite phase of LuBO3 can be stabilized up to 1550 °C at least when the n(Sc)/n(Lu + Sc) ratio was ≥10 at.%. The closed correlations between Sc3+ or Ce3+ molar ratio in the host and luminescence mechanism were discussed in detail. Based on the requirements of steady phase structure, better luminescence efficiency and higher density, the reasonable n(Sc)/n(Lu + Sc) and n(Ce)/n(RE) ratio should be in the range of 30–50 at.% and 0.3–0.5 at.%, respectively. A modified composition, (Lu0.5Sc0.5)0.995Ce0.005BO3 solid solution, was selected to grow single crystal. Its X-ray excited luminescence intensity can be as high as about 27% of LYSO:Ce standard crystal and the effective lifetime is round 20.1 ns. Hence, the cerium-doped Lutetium scandium orthoborate crystal is a promising scintillator for X-ray detection or γ-ray detection.
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the influence of sc lu ratio on the phase transformation and luminescence of cerium doped Lutetium scandium orthoborate solid solutions
2011Co-Authors: Dongzhou Ding, Fan Yang, Shangke Pan, Guohao RenAbstract:Abstract The dependence of structural characteristics of cerium-doped Lutetium scandium orthoborate (Lu1−xScx)BO3:Ce solid solutions on Sc/Lu ratio was investigated. It was found that the calcite phase of LuBO3 can be stabilized up to 1550 °C at least when the n(Sc)/n(Lu + Sc) ratio was ≥10 at.%. The closed correlations between Sc3+ or Ce3+ molar ratio in the host and luminescence mechanism were discussed in detail. Based on the requirements of steady phase structure, better luminescence efficiency and higher density, the reasonable n(Sc)/n(Lu + Sc) and n(Ce)/n(RE) ratio should be in the range of 30–50 at.% and 0.3–0.5 at.%, respectively. A modified composition, (Lu0.5Sc0.5)0.995Ce0.005BO3 solid solution, was selected to grow single crystal. Its X-ray excited luminescence intensity can be as high as about 27% of LYSO:Ce standard crystal and the effective lifetime is round 20.1 ns. Hence, the cerium-doped Lutetium scandium orthoborate crystal is a promising scintillator for X-ray detection or γ-ray detection.
Dongzhou Ding - One of the best experts on this subject based on the ideXlab platform.
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the influence of sc lu ratio on the phase transformation and luminescence of cerium doped Lutetium scandium orthoborate solid solutions
2011Co-Authors: Yuntao Wu, Dongzhou Ding, Fan YangAbstract:Abstract The dependence of structural characteristics of cerium-doped Lutetium scandium orthoborate (Lu1−xScx)BO3:Ce solid solutions on Sc/Lu ratio was investigated. It was found that the calcite phase of LuBO3 can be stabilized up to 1550 °C at least when the n(Sc)/n(Lu + Sc) ratio was ≥10 at.%. The closed correlations between Sc3+ or Ce3+ molar ratio in the host and luminescence mechanism were discussed in detail. Based on the requirements of steady phase structure, better luminescence efficiency and higher density, the reasonable n(Sc)/n(Lu + Sc) and n(Ce)/n(RE) ratio should be in the range of 30–50 at.% and 0.3–0.5 at.%, respectively. A modified composition, (Lu0.5Sc0.5)0.995Ce0.005BO3 solid solution, was selected to grow single crystal. Its X-ray excited luminescence intensity can be as high as about 27% of LYSO:Ce standard crystal and the effective lifetime is round 20.1 ns. Hence, the cerium-doped Lutetium scandium orthoborate crystal is a promising scintillator for X-ray detection or γ-ray detection.
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the influence of sc lu ratio on the phase transformation and luminescence of cerium doped Lutetium scandium orthoborate solid solutions
2011Co-Authors: Dongzhou Ding, Fan Yang, Shangke Pan, Guohao RenAbstract:Abstract The dependence of structural characteristics of cerium-doped Lutetium scandium orthoborate (Lu1−xScx)BO3:Ce solid solutions on Sc/Lu ratio was investigated. It was found that the calcite phase of LuBO3 can be stabilized up to 1550 °C at least when the n(Sc)/n(Lu + Sc) ratio was ≥10 at.%. The closed correlations between Sc3+ or Ce3+ molar ratio in the host and luminescence mechanism were discussed in detail. Based on the requirements of steady phase structure, better luminescence efficiency and higher density, the reasonable n(Sc)/n(Lu + Sc) and n(Ce)/n(RE) ratio should be in the range of 30–50 at.% and 0.3–0.5 at.%, respectively. A modified composition, (Lu0.5Sc0.5)0.995Ce0.005BO3 solid solution, was selected to grow single crystal. Its X-ray excited luminescence intensity can be as high as about 27% of LYSO:Ce standard crystal and the effective lifetime is round 20.1 ns. Hence, the cerium-doped Lutetium scandium orthoborate crystal is a promising scintillator for X-ray detection or γ-ray detection.
Guohao Ren - One of the best experts on this subject based on the ideXlab platform.
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the influence of sc lu ratio on the phase transformation and luminescence of cerium doped Lutetium scandium orthoborate solid solutions
2011Co-Authors: Dongzhou Ding, Fan Yang, Shangke Pan, Guohao RenAbstract:Abstract The dependence of structural characteristics of cerium-doped Lutetium scandium orthoborate (Lu1−xScx)BO3:Ce solid solutions on Sc/Lu ratio was investigated. It was found that the calcite phase of LuBO3 can be stabilized up to 1550 °C at least when the n(Sc)/n(Lu + Sc) ratio was ≥10 at.%. The closed correlations between Sc3+ or Ce3+ molar ratio in the host and luminescence mechanism were discussed in detail. Based on the requirements of steady phase structure, better luminescence efficiency and higher density, the reasonable n(Sc)/n(Lu + Sc) and n(Ce)/n(RE) ratio should be in the range of 30–50 at.% and 0.3–0.5 at.%, respectively. A modified composition, (Lu0.5Sc0.5)0.995Ce0.005BO3 solid solution, was selected to grow single crystal. Its X-ray excited luminescence intensity can be as high as about 27% of LYSO:Ce standard crystal and the effective lifetime is round 20.1 ns. Hence, the cerium-doped Lutetium scandium orthoborate crystal is a promising scintillator for X-ray detection or γ-ray detection.
Daniel B Shin - One of the best experts on this subject based on the ideXlab platform.
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phase i trial of motexafin Lutetium mediated interstitial photodynamic therapy in patients with locally recurrent prostate cancer
2004Co-Authors: C Diana Hsiung M D Stripp, Rosemarie Mick, Timothy C Zhu, Richard Whittington, R Debbie N Smith, Andreea Dimofte, Jarod C Finlay, Jeremy Miles, Theresa M Busch, Daniel B ShinAbstract:Therapeutic options for patients with locally recurrent prostate cancer after treatment with radiation therapy are limited. An ongoing Phase I trial of interstitial photodynamic therapy (PDT) with the photosensitizer motexafin Lutetium (MLu) was initiated in year 2000 for men with locally recurrent prostate cancer. The primary objective of this trial is to determine the maximally tolerated dose of motexafin Lutetium-mediated PDT. Twelve men with biopsy-proven recurrent prostate cancer and no evidence of distant metastatic disease have been enrolled. Pre-treatment evaluation included an MRI of the prostate, bone scan, laboratory studies, cystoscopy, and transrectal ultrasound. Treatment plans were generated based upon the ultrasound findings. PDT dose was escalated by increasing the motexafin Lutetium dose, increasing the 732 nm light dose, and decreasing the drug-light interval. Motexafin Lutetium doses ranged from 0.5 to 2 mg/kg administered IV 3, 6, or 24 hours prior to 732 nm light delivery. The light dose measured in real time with in situ spherical detectors was 25-100 J/cm2 for all patients. Light was delivered through optical fibers inserted through a transperineal brachytherapy template in the operating room and optical property measurements were made before and after light therapy. Prostate biopsies were obtained before and after light delivery for spectrofluorometric measurements of photosensitizer uptake. Twelve patients have completed protocol treatment on eight dose levels without dose-limiting toxicity. Grade I PDT-related genitourinary symptoms were observed. One patient had Grade II urinary urgency that was urinary catheter-related. No rectal or other GI PDT-related toxicities were observed. Measurements of motexafin Lutetium in prostate tissue demonstrated the presence of photosensitizer at all dose levels. Conclusions: Motexafin Lutetium-mediated PDT designed to treat comprehensively the entired prostate gland has been well-tolerated at the doses studied to date.
V Gorbenko - One of the best experts on this subject based on the ideXlab platform.
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rare earth antisites in Lutetium aluminum garnets influence on lattice parameter and ce3 multicenter structure
2014Co-Authors: H Przybylinska, M Nikl, A Wittlin, M G Brik, A Kaminska, P Sybilski, Yu Zorenko, V GorbenkoAbstract:Abstract Low temperature, infrared transmission spectra of Lutetium aluminum garnet (LuAG) bulk crystals and epitaxial layers doped with Ce are presented. In the region of intra-configurational 4f–4f transitions the spectra of the bulk LuAG crystal exhibit the signatures of several different Ce3+ related centers. Apart from the dominant center, associated with Ce substituting Lutetium, at least six other centers are found, some of them attributed to so-called antisite locations of rare-earth ions in the garnet host, i.e., ions in the Al positions. X-ray diffraction data prove lattice expansion of bulk LuAG crystals due presence of rare-earth antisites.
