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Laurent Lagadic - One of the best experts on this subject based on the ideXlab platform.
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Experimental study of stochastic processes in populations of the pond snail Lymnaea stagnalis
2005Co-Authors: Marie-agnès Coutellec, Laurent LagadicAbstract:Experimental study of stochastic processes in populations of the pond snail[i] Lymnaea stagnalis[/i]. 15. Annual meeting SETAC Europe
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Inhibition of hemocyte-mediated immune functions in Lymnaea stagnalis exposed to the diphenylether herbicide fomesafen.
2005Co-Authors: Laurent Lagadic, Jacqueline RussoAbstract:Inhibition of hemocyte-mediated immune functions in Lymnaea stagnalis exposed to the diphenylether herbicide fomesafen.. 15. Europe Annual Meeting of SETAC
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Cell redox environment and detoxication enzyme activities Lymnaea stagnalis exposed to diquat and fomesafen with and without Agral 90
2005Co-Authors: Luz Lefeuvre-orfila, Jacqueline Russo, Micheline Heydorff, Laurent LagadicAbstract:Cell redox environment and detoxication enzyme activities Lymnaea stagnalis exposed to diquat and fomesafen with and without Agral 90. 15. Europe Annual Meeting of SETAC
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Lysosomal fragility facing environmental reality : Application of the Neutral-Red Retention Time assay to hemocytes from atrazine-exposed Lymnaea stagnalis
2005Co-Authors: Jacqueline Russo, Laurent LagadicAbstract:Lysosomal fragility facing environmental reality : Application of the Neutral-Red Retention Time assay to hemocytes from atrazine-exposed Lymnaea stagnalis. 15. Europe Annual Meeting of SETAC
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Influence of the complexity of aquatic test systems on the fate of vinclozolin and its reprotoxic effects in Lymnaea stagnalis.
2005Co-Authors: Laurent Lagadic, Micheline Heydorff, Julian Bursztyka, Maryse Baradat, Sophie Lorber, Didier Azam, Alphonse Quemeneur, Jean Pierre CravediAbstract:Influence of the complexity of aquatic test systems on the fate of vinclozolin and its reprotoxic effects in Lymnaea stagnalis.. 15. Europe Annual Meeting of SETAC
Marie-agnès Coutellec - One of the best experts on this subject based on the ideXlab platform.
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ion channel profiling of the Lymnaea stagnalis ganglia via transcriptome analysis
BMC Genomics, 2021Co-Authors: Nancy Dong, Zhaolei Zhang, Julia Bandura, Yan Wang, Karine Labadie, Benjamin Noel, Angus Davison, Joris M Koene, Hongshuo Sun, Marie-agnès CoutellecAbstract:Background The pond snail Lymnaea stagnalis (L. stagnalis) has been widely used as a model organism in neurobiology, ecotoxicology, and parasitology due to the relative simplicity of its central nervous system (CNS). However, its usefulness is restricted by a limited availability of transcriptome data. While sequence information for the L. stagnalis CNS transcripts has been obtained from EST libraries and a de novo RNA-seq assembly, the quality of these assemblies is limited by a combination of low coverage of EST libraries, the fragmented nature of de novo assemblies, and lack of reference genome. Results In this study, taking advantage of the recent availability of a preliminary L. stagnalis genome, we generated an RNA-seq library from the adult L. stagnalis CNS, using a combination of genome-guided and de novo assembly programs to identify 17,832 protein-coding L. stagnalis transcripts. We combined our library with existing resources to produce a transcript set with greater sequence length, completeness, and diversity than previously available ones. Using our assembly and functional domain analysis, we profiled L. stagnalis CNS transcripts encoding ion channels and ionotropic receptors, which are key proteins for CNS function, and compared their sequences to other vertebrate and invertebrate model organisms. Interestingly, L. stagnalis transcripts encoding numerous putative Ca2+ channels showed the most sequence similarity to those of Mus musculus, Danio rerio, Xenopus tropicalis, Drosophila melanogaster, and Caenorhabditis elegans, suggesting that many calcium channel-related signaling pathways may be evolutionarily conserved. Conclusions Our study provides the most thorough characterization to date of the L. stagnalis transcriptome and provides insights into differences between vertebrates and invertebrates in CNS transcript diversity, according to function and protein class. Furthermore, this study provides a complete characterization of the ion channels of Lymnaea stagnalis, opening new avenues for future research on fundamental neurobiological processes in this model system.
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Xénobiotiques et processus stochastiques dans les populations exposées : approche expérimentale chez Lymnaea stagnalis.
2006Co-Authors: Marie-agnès CoutellecAbstract:Xénobiotiques et processus stochastiques dans les populations exposées : approche expérimentale chez Lymnaea stagnalis.. 3. Séminaire d'Ecotoxicologie de l'INRA
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Experimental study of stochastic processes in populations of the pond snail Lymnaea stagnalis
2005Co-Authors: Marie-agnès Coutellec, Laurent LagadicAbstract:Experimental study of stochastic processes in populations of the pond snail[i] Lymnaea stagnalis[/i]. 15. Annual meeting SETAC Europe
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Influence of contaminants on demographic and evolutionary stochastic processes in the freswater snail Lymnaea stagnalis ; an experimental approach
2004Co-Authors: Marie-agnès Coutellec, Thierry Caquet, Marc Roucaute, Laurent LagadicAbstract:Influence of contaminants on demographic and evolutionary stochastic processes in the freswater snail Lymnaea stagnalis ; an experimental approach. 4. World Congress of SETAC
Paul R. Benjamin - One of the best experts on this subject based on the ideXlab platform.
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The unlimited potential of the great pond snail, Lymnaea stagnalis.
eLife, 2020Co-Authors: István Fodor, Paul R. Benjamin, Joris M Koene, Ahmed Aa Hussein, Zsolt PirgerAbstract:Only a limited number of animal species lend themselves to becoming model organisms in multiple biological disciplines: one of these is the great pond snail, Lymnaea stagnalis. Extensively used since the 1970s to study fundamental mechanisms in neurobiology, the value of this freshwater snail has been also recognised in fields as diverse as host-parasite interactions, ecotoxicology, evolution, genome editing and 'omics', and human disease modelling. While there is knowledge about the natural history of this species, what is currently lacking is an integration of findings from the laboratory and the field. With this in mind, this article aims to summarise the applicability of L. stagnalis and points out that this multipurpose model organism is an excellent, contemporary choice for addressing a large range of different biological questions, problems and phenomena.
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Computational model of a modulatory cell type in the feeding network of the snail, Lymnaea stagnalis
BMC Neuroscience, 2007Co-Authors: Dimitris V. Vavoulis, Paul R. Benjamin, Eugeny S. Nikitin, Jianfeng Feng, György KemenesAbstract:Realistic mathematical models of single neurons are significant in assessing the contribution of specific ionic conductances to neuronal excitability. This study presents a detailed computational model of the Cerebral Giant Cells (CGCs), a pair of serotonergic neurons in the feeding network of Lymnaea stagnalis, which are critical for the expression of motor behaviour (feeding) and the formation of long-term memory.
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neurophysiological correlates of unconditioned and conditioned feeding behavior in the pond snail Lymnaea stagnalis
Journal of Neurophysiology, 1998Co-Authors: Kevin Staras, György Kemenes, Paul R. BenjaminAbstract:Staras, Kevin, Gyorgy Kemenes, and Paul R. Benjamin. Neurophysiological correlates of unconditioned and conditioned feeding behavior in the pond snail Lymnaea stagnalis. J. Neurophysiol. 79: 3030–3...
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In Vitro Appetitive Classical Conditioning of the Feeding Response in the Pond Snail Lymnaea stagnalis
Journal of neurophysiology, 1997Co-Authors: György Kemenes, Kevin Staras, Paul R. BenjaminAbstract:Kemenes, Gyorgy, Kevin Staras, and Paul R. Benjamin. In vitro appetitive classical conditioning of the feeding response in the pond snail Lymnaea stagnalis. J. Neurophysiol. 78: 2351–2362, 1997. An...
György Kemenes - One of the best experts on this subject based on the ideXlab platform.
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Computational model of a modulatory cell type in the feeding network of the snail, Lymnaea stagnalis
BMC Neuroscience, 2007Co-Authors: Dimitris V. Vavoulis, Paul R. Benjamin, Eugeny S. Nikitin, Jianfeng Feng, György KemenesAbstract:Realistic mathematical models of single neurons are significant in assessing the contribution of specific ionic conductances to neuronal excitability. This study presents a detailed computational model of the Cerebral Giant Cells (CGCs), a pair of serotonergic neurons in the feeding network of Lymnaea stagnalis, which are critical for the expression of motor behaviour (feeding) and the formation of long-term memory.
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neurophysiological correlates of unconditioned and conditioned feeding behavior in the pond snail Lymnaea stagnalis
Journal of Neurophysiology, 1998Co-Authors: Kevin Staras, György Kemenes, Paul R. BenjaminAbstract:Staras, Kevin, Gyorgy Kemenes, and Paul R. Benjamin. Neurophysiological correlates of unconditioned and conditioned feeding behavior in the pond snail Lymnaea stagnalis. J. Neurophysiol. 79: 3030–3...
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In Vitro Appetitive Classical Conditioning of the Feeding Response in the Pond Snail Lymnaea stagnalis
Journal of neurophysiology, 1997Co-Authors: György Kemenes, Kevin Staras, Paul R. BenjaminAbstract:Kemenes, Gyorgy, Kevin Staras, and Paul R. Benjamin. In vitro appetitive classical conditioning of the feeding response in the pond snail Lymnaea stagnalis. J. Neurophysiol. 78: 2351–2362, 1997. An...
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The modulatory peptide SCPb inhibits feeding in the mollusc Lymnaea stagnalis
1991Co-Authors: C.j.h. Elliott, György Kemenes, Simon N. WaddingtonAbstract:1. Injection of SCPb (10e-5M) into the pond snail Lymnaea stagnalis inhibits both the feeding response to sucrose and spontaneous rasping. 2. Application of 10e-5M SCPb to the isolated CNS has no effect on the fictive feeding rhythm. 3. These results differ from those from other molluscs where SCPb often has an excitatory effect on the feeding system.
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The modulatory peptide SCPb inhibits feeding in the mollusc, Lymnaea stagnalis
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1991Co-Authors: C.j.h. Elliott, György Kemenes, Simon N. WaddingtonAbstract:Abstract 1. Injection of SCPb (10−5 M) into the pond snail Lymnaea stagnalis inhibits both the feeding response to sucrose and spontaneous rasping. 2. Application of 10−5 M SCPb to the isolated CNS has no effect on the fictive feeding rhythm. 3. These results differ from those from other molluscs where SCPb often has an excitatory effect on the feeding system.
Özkan Ünver - One of the best experts on this subject based on the ideXlab platform.
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Histopathological effects in tissues of snail Lymnaea stagnalis (Gastropoda, Pulmonata) exposed to sublethal concentration of Thiodan and recovery after exposure.
Journal of applied toxicology : JAT, 2005Co-Authors: Erhan Ünlü, Elif Ipek Cengiz, Mehmet Yildirim, Birgül Otludil, Özkan ÜnverAbstract:Histopathological alterations induced by Thiodan® in three tissues, namely, digestive gland, foot and mantle, of the freshwater snail Lymnaea stagnalis were investigated. Specimens of Lymnaea stagnalis were exposed to 0.36% and 0.72% Thiodan® 35 EC, a commercial grade of endosulfan, for 96 h followed by a recovery period of 30 days. Thiodan® caused significant dose dependent histopathological changes in all the tissues of the snail. Irreversible necrotic changes occurred in the digestive gland of the snail following Thiodan® exposure. Degenerative changes in the muscle fiber of the foot, protein and pigment cells of the foot and the connective tissue element of the mantle were recovered after 30 days of recovery of the snail in pesticide-free freshwater. Copyright © 2005 John Wiley & Sons, Ltd.
