The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
Elisabeth M Dykens - One of the best experts on this subject based on the ideXlab platform.
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correlates of Maladaptive Behavior in individuals with 5p cri du chat syndrome
Developmental Medicine & Child Neurology, 2008Co-Authors: David Clarke, Elisabeth M DykensAbstract:This study examined the range, distinctiveness, and correlates of Maladaptive Behavior in 146 subjects with 5p- (cri du chat) syndrome using the Aberrant Behavior Checklist as a standardized measure. Hyperactivity was the most significant and frequent problem in the sample. Subjects with 5p- syndrome also showed aggression, tantrums, self-injurious Behavior, and stereotypies; some of these problems were more pronounced in individuals with lower cognitive-adaptive levels, as well as in those with histories of previous medication trials. Autistic-like features and social withdrawal were more characteristic of individuals with translocations as opposed to deletions, even when controlling for the lower adaptive level of the translocation group. These findings encourage further research on the Behavior of individuals with 5p- syndrome.
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136 adaptive and Maladaptive Behavior of males with sex chromosome aneuploidy
Journal of Investigative Medicine, 2006Co-Authors: Jeannie Visootsak, Elisabeth M Dykens, Eth A Rosne, N Tartaglia, Joh M GrahamAbstract:Background Sex chromosomal aneuploidy is the most common disorder of sex chromosomes in humans, with an incidence of 1 in 400 newborns. The addition of more than one extra X and/or Y chromosome to a normal male karyotype of 46,XY is less frequent and has its own distinctive Behavioral profile. This study is the first to investigate the effects of increasing number of extra Xs and Y on Behavioral phenotypes and specific treatment strategies are suggested for anticipatory guidance. Objectives To examine the Behavioral similarities and differences of males with 48,XXYY compared to 48,XXXY and 49,XXXXY. Methods Participants in this study consisted of two groups: 11 males with 48,XXYY (mean age 21.83) and 13 males with 48,XXXY and 49,XXXXY (mean age 21.08). All families completed comprehensive neuropsychological questionnaires: Vineland Adaptive Behavioral Scales, Child Behavior Checklist and Reiss Personality Profiles. Results On the Vineland Adaptive Behavioral Scales, males with 48,XXYY score higher than males with 48,XXXY and 49,XXXXY in daily living skills, communication, and socialization. The communication domain is the lowest in both groups. Internalizing and externalizing Behaviors are higher in males with 48,XXYY (p Conclusions 48,XXYY subjects have higher overall adaptive scales in daily living skills, socialization, and communication. Males with 48,XXXY and 49,XXXXY are lower functioning cognitively compared to 48,XXYY since each X reduces the overall IQ by 15 points. Both groups have early language deficits that result in significant lower scores in the communication domain. Their primary communicative problems may result in Maladaptive Behaviors by both groups, although 48,XXYY males are at a higher risk. These findings reveal distinctive differences in both groups and may provide insights for specific early intervention and anticipatory guidance strategies.
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Maladaptive Behavior differences in prader willi syndrome due to paternal deletion versus maternal uniparental disomy
American Journal on Mental Retardation, 1999Co-Authors: Elisabeth M Dykens, Suzanne Cassidy, Ya H KingAbstract:Maladaptive Behavior was compared across 23 people with Prader-Willi syndrome due to paternal deletion to 23 age- and gender-matched subjects with maternal uniparental disomy. Controlling for the higher IQs of the uniparental disomy group, deleted cases showed significantly higher Maladaptive ratings on the Child Behavior Checklist's Internalizing, Externalizing, and Total domains as well as more symptom-related distress on the Yale-Brown Obsessive-Compulsive Scale. Across both measures, deleted cases were more apt to skin-pick, bite their nails, hoard, overeat, sulk, and withdraw. A dampening of symptom severity is suggested in Prader-Willi syndrome cases due to maternal uniparental disomy. Findings are compared to Angelman syndrome, and possible genetic mechanisms are discussed, as are implications for Prader-Willi syndrome and obsessive-compulsive Behaviors.
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Maladaptive Behavior in children with prader willi syndrome down syndrome and nonspecific mental retardation
American Journal on Mental Retardation, 1997Co-Authors: Elisabeth M Dykens, Connie KasariAbstract:Although some genetic, mental retardation syndromes have well-described Behavioral features, comparative studies have not yet assessed the relative uniqueness of these so-called phenotypes. Maladaptive Behavior of 43 children with Prader-Willi syndrome was compared to age- and gender-matched children with Down syndrome and with nonspecific mental retardation. The Prader-Willi group showed more frequent and severe internalizing, externalizing, and total problem Behaviors on the Child Behavior Checklist. Some problems were elevated in all groups, and 12 Behaviors were significantly elevated in Prader-Willi subjects relative to both comparison groups. Seven Behaviors predicted membership into the Prader-Willi group with 91% accuracy. Implications were discussed for research on Behavioral phenotypes in general and for dual diagnosis in particular.
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correlates of Maladaptive Behavior in children and adults with prader willi syndrome
American Journal of Medical Genetics, 1995Co-Authors: Elisabeth M Dykens, Suzanne CassidyAbstract:Four features of Maladaptive Behavior were examined in 25 children and 61 adults with Prader-Willi syndrome: age, gender, IQ, and the Body Mass Index (BMI). Among children, older subjects showed increased symptomatology relative to younger subjects, especially in depression and withdrawal. Among adults, Maladaptive Behaviors seem to show both steady and variable expressions, waxing and waning over time. Boys showed heightened depression relative to girls, findings which were not seen in the adults. No Maladaptive Behavior differences were found in high vs. low IQ subjects. Thinner adults with lower BMIs had higher Maladaptive Behavior scores relative to heavier subjects, particularly in internal states involving distressful affect and problems with thinking. Several explanations of these counterintuitive BMI findings are discussed, as is the need for prospective research on Maladaptive Behavior in children and adults with this syndrome. © 1995 Wiley-Liss, Inc.
Bo Hedblad - One of the best experts on this subject based on the ideXlab platform.
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Behavior in a stressful situation personality factors and disease severity in patients with acute myocardial infarction baseline findings from the prospective cohort study secami the secondary prevention and compliance following acute myocardial infa
BMC Cardiovascular Disorders, 2011Co-Authors: Lena Andrepetersson, Mona Schlyter, Patrik Tyden, Gunnar Engström, Bo HedbladAbstract:Background Psychosocial stress has been identified as a risk factor in association with cardiovascular disease but less attention has been paid to heterogeneity in vulnerability to stress. The serial Color Word Test (CWT) measures adaptation to a stressful situation and it can be used to identify individuals that are vulnerable to stress. Prospective studies have shown that individuals with a Maladaptive Behavior in this test are exposed to an increased risk of future cardiovascular events. The aim of the present study was to investigate whether Maladaptive Behavior in the serial CWT alone or in combination with any specific personality dimension was associated with severity of myocardial infarction (MI).
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social support and Behavior in a stressful situation in relation to myocardial infarction and mortality who is at risk results from prospective cohort study men born in 1914 malmo sweden
International Journal of Behavioral Medicine, 2006Co-Authors: Lena Andrepetersson, Bo Hedblad, Lars Janzon, Perolof OstergrenAbstract:Coronary heart disease remains an important cause of morbidity and mortality. Much data support the view that social support is associated with coronary heart disease. Participants of the study “Men born in 1914,” (414 men) were followed from a baseline measurement in 1982/83 until the end of 1996. At baseline, the men answered a questionnaire on social support and participated in a stressful test where their Behavior was categorized as adaptive or Maladaptive. This study examined whether social support had a prospective impact on the incidence of myocardial infarction and all-cause mortality when Behavior in the stressful task was taken into consideration. The conclusion of the study was that unsatisfactory levels of social support is associated with an increased risk of incident myocardial infarction (HR 2.40, CI 1.36-4.25, p = .003) and premature death (HR 1.99, CI 1.32-3.00, p = .001) but only in men who had shown Maladaptive Behavior in the test.
Lena Andrepetersson - One of the best experts on this subject based on the ideXlab platform.
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Behavior in a stressful situation personality factors and disease severity in patients with acute myocardial infarction baseline findings from the prospective cohort study secami the secondary prevention and compliance following acute myocardial infa
BMC Cardiovascular Disorders, 2011Co-Authors: Lena Andrepetersson, Mona Schlyter, Patrik Tyden, Gunnar Engström, Bo HedbladAbstract:Background Psychosocial stress has been identified as a risk factor in association with cardiovascular disease but less attention has been paid to heterogeneity in vulnerability to stress. The serial Color Word Test (CWT) measures adaptation to a stressful situation and it can be used to identify individuals that are vulnerable to stress. Prospective studies have shown that individuals with a Maladaptive Behavior in this test are exposed to an increased risk of future cardiovascular events. The aim of the present study was to investigate whether Maladaptive Behavior in the serial CWT alone or in combination with any specific personality dimension was associated with severity of myocardial infarction (MI).
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social support and Behavior in a stressful situation in relation to myocardial infarction and mortality who is at risk results from prospective cohort study men born in 1914 malmo sweden
International Journal of Behavioral Medicine, 2006Co-Authors: Lena Andrepetersson, Bo Hedblad, Lars Janzon, Perolof OstergrenAbstract:Coronary heart disease remains an important cause of morbidity and mortality. Much data support the view that social support is associated with coronary heart disease. Participants of the study “Men born in 1914,” (414 men) were followed from a baseline measurement in 1982/83 until the end of 1996. At baseline, the men answered a questionnaire on social support and participated in a stressful test where their Behavior was categorized as adaptive or Maladaptive. This study examined whether social support had a prospective impact on the incidence of myocardial infarction and all-cause mortality when Behavior in the stressful task was taken into consideration. The conclusion of the study was that unsatisfactory levels of social support is associated with an increased risk of incident myocardial infarction (HR 2.40, CI 1.36-4.25, p = .003) and premature death (HR 1.99, CI 1.32-3.00, p = .001) but only in men who had shown Maladaptive Behavior in the test.
Suzanne Cassidy - One of the best experts on this subject based on the ideXlab platform.
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Maladaptive Behavior differences in prader willi syndrome due to paternal deletion versus maternal uniparental disomy
American Journal on Mental Retardation, 1999Co-Authors: Elisabeth M Dykens, Suzanne Cassidy, Ya H KingAbstract:Maladaptive Behavior was compared across 23 people with Prader-Willi syndrome due to paternal deletion to 23 age- and gender-matched subjects with maternal uniparental disomy. Controlling for the higher IQs of the uniparental disomy group, deleted cases showed significantly higher Maladaptive ratings on the Child Behavior Checklist's Internalizing, Externalizing, and Total domains as well as more symptom-related distress on the Yale-Brown Obsessive-Compulsive Scale. Across both measures, deleted cases were more apt to skin-pick, bite their nails, hoard, overeat, sulk, and withdraw. A dampening of symptom severity is suggested in Prader-Willi syndrome cases due to maternal uniparental disomy. Findings are compared to Angelman syndrome, and possible genetic mechanisms are discussed, as are implications for Prader-Willi syndrome and obsessive-compulsive Behaviors.
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correlates of Maladaptive Behavior in children and adults with prader willi syndrome
American Journal of Medical Genetics, 1995Co-Authors: Elisabeth M Dykens, Suzanne CassidyAbstract:Four features of Maladaptive Behavior were examined in 25 children and 61 adults with Prader-Willi syndrome: age, gender, IQ, and the Body Mass Index (BMI). Among children, older subjects showed increased symptomatology relative to younger subjects, especially in depression and withdrawal. Among adults, Maladaptive Behaviors seem to show both steady and variable expressions, waxing and waning over time. Boys showed heightened depression relative to girls, findings which were not seen in the adults. No Maladaptive Behavior differences were found in high vs. low IQ subjects. Thinner adults with lower BMIs had higher Maladaptive Behavior scores relative to heavier subjects, particularly in internal states involving distressful affect and problems with thinking. Several explanations of these counterintuitive BMI findings are discussed, as is the need for prospective research on Maladaptive Behavior in children and adults with this syndrome. © 1995 Wiley-Liss, Inc.
Perolof Ostergren - One of the best experts on this subject based on the ideXlab platform.
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social support and Behavior in a stressful situation in relation to myocardial infarction and mortality who is at risk results from prospective cohort study men born in 1914 malmo sweden
International Journal of Behavioral Medicine, 2006Co-Authors: Lena Andrepetersson, Bo Hedblad, Lars Janzon, Perolof OstergrenAbstract:Coronary heart disease remains an important cause of morbidity and mortality. Much data support the view that social support is associated with coronary heart disease. Participants of the study “Men born in 1914,” (414 men) were followed from a baseline measurement in 1982/83 until the end of 1996. At baseline, the men answered a questionnaire on social support and participated in a stressful test where their Behavior was categorized as adaptive or Maladaptive. This study examined whether social support had a prospective impact on the incidence of myocardial infarction and all-cause mortality when Behavior in the stressful task was taken into consideration. The conclusion of the study was that unsatisfactory levels of social support is associated with an increased risk of incident myocardial infarction (HR 2.40, CI 1.36-4.25, p = .003) and premature death (HR 1.99, CI 1.32-3.00, p = .001) but only in men who had shown Maladaptive Behavior in the test.
