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V Rangari - One of the best experts on this subject based on the ideXlab platform.

  • Immunomodulatory activity of alcoholic extract of Mangifera indica L. in mice.
    Journal of ethnopharmacology, 2001
    Co-Authors: N Makare, S Bodhankar, V Rangari
    Abstract:

    Mangifera indica Linn, a plant widely used in the traditional medicinal systems of India, has been reported to possess antiviral, antibacterial and anti-inflammatory activities. In the present study, the alcoholic extract of stem bark of Mangifera indica Linn (Extract I containing mangiferin 2.6%), has been investigated for its effect on cell mediated and humoral components of the immune system in mice. Administration of test extract I produced increase in humoral antibody (HA) titre and delayed type hypersensitivity (DTH) in mice. It is concluded that test extract I is a promising drug with immunostimulant properties.

N Makare - One of the best experts on this subject based on the ideXlab platform.

  • Immunomodulatory activity of alcoholic extract of Mangifera indica L. in mice.
    Journal of ethnopharmacology, 2001
    Co-Authors: N Makare, S Bodhankar, V Rangari
    Abstract:

    Mangifera indica Linn, a plant widely used in the traditional medicinal systems of India, has been reported to possess antiviral, antibacterial and anti-inflammatory activities. In the present study, the alcoholic extract of stem bark of Mangifera indica Linn (Extract I containing mangiferin 2.6%), has been investigated for its effect on cell mediated and humoral components of the immune system in mice. Administration of test extract I produced increase in humoral antibody (HA) titre and delayed type hypersensitivity (DTH) in mice. It is concluded that test extract I is a promising drug with immunostimulant properties.

B. A. S. Lawal - One of the best experts on this subject based on the ideXlab platform.

  • Evaluation of the antidiabetic action of Mangifera indica in mice
    Phytotherapy research : PTR, 2001
    Co-Authors: Adegbuyi Oladele Aderibigbe, T. S. Emudianughe, B. A. S. Lawal
    Abstract:

    The leaves of Mangifera indica were assessed for antidiabetic properties using normoglycaemic, glucose-induced hyperglycaemia and streptozotocin (STZ) induced diabetic mice. The aqueous extract produced a reduction of blood glucose level in normoglycaemic and glucose-induced hyperglycaemia, but did not have any effect on streptozotocin-induced diabetic mice. The hypoglycaemic effect of the aqueous extract was compared with that of an oral dose of chlorpropamide under the same conditions. The results of this study indicate that the aqueous extract of the leaves of Mangifera indica possess hypoglycaemic activity.

  • Antihyperglycaemic effect of Mangifera indica in rat
    Phytotherapy research : PTR, 1999
    Co-Authors: Adegbuyi Oladele Aderibigbe, T. S. Emudianughe, B. A. S. Lawal
    Abstract:

    The leaves of Mangifera indica are used as an antidiabetic agent in Nigerian folk medicine. To determine whether or not there is a scientific basis for this use, the effect of the aqueous extract of the leaves on blood glucose level was assessed in normoglycaemic, glucose - induced hyperglycaemic and streptozotocin (STZ)-induced diabetic rats. The aqueous extract given orally (1 g/kg) did not alter the blood glucose levels in either normoglycaemic or STZ-induced diabetic rats. In glucose - induced hyperglycaemia, however, antidiabetic activity was seen when the extract and glucose were administered simultaneously and also when the extract was given to the rats 60 min before the glucose. The hypoglycaemic effect of the aqueous extract was compared with that of an oral dose of chlorpropamide (200 mg/kg) under the same conditions. The results of this study indicate that the aqueous extract of the leaves of Mangifera indica possess hypoglycaemic activity. This action may be due to an intestinal reduction of the absorption of glucose. However, other different mechanisms of action cannot be excluded.

S Bodhankar - One of the best experts on this subject based on the ideXlab platform.

  • Immunomodulatory activity of alcoholic extract of Mangifera indica L. in mice.
    Journal of ethnopharmacology, 2001
    Co-Authors: N Makare, S Bodhankar, V Rangari
    Abstract:

    Mangifera indica Linn, a plant widely used in the traditional medicinal systems of India, has been reported to possess antiviral, antibacterial and anti-inflammatory activities. In the present study, the alcoholic extract of stem bark of Mangifera indica Linn (Extract I containing mangiferin 2.6%), has been investigated for its effect on cell mediated and humoral components of the immune system in mice. Administration of test extract I produced increase in humoral antibody (HA) titre and delayed type hypersensitivity (DTH) in mice. It is concluded that test extract I is a promising drug with immunostimulant properties.

Adegbuyi Oladele Aderibigbe - One of the best experts on this subject based on the ideXlab platform.

  • Evaluation of the antidiabetic action of Mangifera indica in mice
    Phytotherapy research : PTR, 2001
    Co-Authors: Adegbuyi Oladele Aderibigbe, T. S. Emudianughe, B. A. S. Lawal
    Abstract:

    The leaves of Mangifera indica were assessed for antidiabetic properties using normoglycaemic, glucose-induced hyperglycaemia and streptozotocin (STZ) induced diabetic mice. The aqueous extract produced a reduction of blood glucose level in normoglycaemic and glucose-induced hyperglycaemia, but did not have any effect on streptozotocin-induced diabetic mice. The hypoglycaemic effect of the aqueous extract was compared with that of an oral dose of chlorpropamide under the same conditions. The results of this study indicate that the aqueous extract of the leaves of Mangifera indica possess hypoglycaemic activity.

  • Antihyperglycaemic effect of Mangifera indica in rat
    Phytotherapy research : PTR, 1999
    Co-Authors: Adegbuyi Oladele Aderibigbe, T. S. Emudianughe, B. A. S. Lawal
    Abstract:

    The leaves of Mangifera indica are used as an antidiabetic agent in Nigerian folk medicine. To determine whether or not there is a scientific basis for this use, the effect of the aqueous extract of the leaves on blood glucose level was assessed in normoglycaemic, glucose - induced hyperglycaemic and streptozotocin (STZ)-induced diabetic rats. The aqueous extract given orally (1 g/kg) did not alter the blood glucose levels in either normoglycaemic or STZ-induced diabetic rats. In glucose - induced hyperglycaemia, however, antidiabetic activity was seen when the extract and glucose were administered simultaneously and also when the extract was given to the rats 60 min before the glucose. The hypoglycaemic effect of the aqueous extract was compared with that of an oral dose of chlorpropamide (200 mg/kg) under the same conditions. The results of this study indicate that the aqueous extract of the leaves of Mangifera indica possess hypoglycaemic activity. This action may be due to an intestinal reduction of the absorption of glucose. However, other different mechanisms of action cannot be excluded.