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Zaheen A. Iqbal - One of the best experts on this subject based on the ideXlab platform.

  • Postural stability in people with visual impairment.
    Brain and behavior, 2019
    Co-Authors: Ahmad H. Alghadir, Abdullah Z. Alotaibi, Zaheen A. Iqbal
    Abstract:

    Background The visual system enables the brain to assess information regarding the position of the body in space. Congenital or acquired blindness leads to the development of abnormal sensory-motor interactions that results in development of typical musculoskeletal deformities and gait patterns that cause disability. Diabetes and related complications are expected to increase exponentially in the next 10 years; thus, the number of people with visual impairment is expected to increase. However, there have been few studies regarding etio-pathogenesis of postural alteration and balance impairment in people with visual impairment; moreover, no previous study has investigated postural stability in this population. This study aimed to assess the center of gravity (COG) velocity in subjects with visual impairment and compared with that in sighted subjects. Methods Seventy male subjects, 20-40 years of age, participated in this study; they were divided into sighted (control) and visually impaired groups. COG velocity while standing on an unstable surface was measured using the NeuroCom® Balance Master Version 8.5.0. For the sighted group, data were recorded with eyes open and then with eyes closed. For the visually impaired group, no instructions were given with respect to eyes during data collection. Results Mean COG velocity was significantly higher in the visually impaired group than in the sighted group with eyes open. However, there was no difference in mean COG velocity between the visually impaired group and the sighted group with eyes closed. The difference in mean COG velocity between sighted subjects with eyes open and eyes closed was also significant. Mean COG velocity while standing on a foam surface varied among visually impaired subjects and sighted subjects with eyes open and closed. Conclusion This study showed that subjects with visual impairment, regardless of eye opening or closure, behave in the same manner as sighted subjects with eyes closed.

  • Effect of tongue position on postural stability during quiet standing in healthy young males.
    Somatosensory & motor research, 2015
    Co-Authors: Ahmad H. Alghadir, Hamayun Zafar, Zaheen A. Iqbal
    Abstract:

    AbstractBackground and aims: Role of the neck and jaw sensory motor system in control of body balance has been established. Tongue is an integral part of jaw sensory motor system and helps in execution of purposeful and precise motor tasks like eating, drinking and speaking. The purpose of this study was to evaluate the possible effects of tongue position on the postural control system.Materials and method: We compared the mean center of gravity (COG) velocity during quiet standing on an unstable surface with eyes closed during two test conditions: (i) with habitual jaw resting position and (ii) with instructed tongue positioned against the upper incisors. One hundred and sixteen normal healthy male subjects (average age 31.56 ± 8.51 years and height 170.86 ± 7.26 cm) participated in the study. Their COG velocity (deg/s) was measured using the NeuroCom® Balance Master Version 8.5.0 (Clackamas, OR, USA).Results and conclusions: The results show that COG velocity decreased significantly while tongue was pos...

  • Effect of chewing on postural stability during quiet standing in healthy young males
    Somatosensory & motor research, 2014
    Co-Authors: Ahmad H. Alghadir, Hamayun Zafar, Susan L. Whitney, Zaheen A. Iqbal
    Abstract:

    AbstractBackground and aims: There is an important role of the neck sensory motor system in control of body posture and balance, and it is reasonable to believe that the jaw sensory motor system can directly and indirectly influence the modulation of the postural control system. The purpose of this study was to evaluate possible effects of dynamic jaw position while chewing on the postural control system.Materials and methods: We compared the mean center of gravity (COG) velocity during quite standing on a foam surface with eyes closed during three test conditions: (i) with resting jaw position, (ii) with open jaw position, and (iii) while chewing standard bolus of chewing gum. One hundred and sixteen normal healthy male subjects (average age 31.56 ± 8.51 years; height 170.86 ± 7.26 cm) were recruited for the study. Their COG velocity (deg/s) was measured using the NeuroCom® Balance Master Version 8.5.0 (Clackamas, OR, USA).Statistical analysis: Data was tested by the Friedman test.Results and conclusions...

Florian M. E. Wagenlehner - One of the best experts on this subject based on the ideXlab platform.

  • Greek Version of the Acute Cystitis Symptom Score. Part I: Linguistic Validation
    2020
    Co-Authors: Konstantinos Stamatiou, Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Evangelia Samara, Florian M. E. Wagenlehner
    Abstract:

    Objective: The Acute Cystitis Symptom Score (ACSS) was developed and validated as a self-reporting questionnaire for diagnosing and monitoring acute, uncomplicated cystitis (AC) in female patients. The study aims at the translation of the ACSS into Greek from original Russian as a source and American English as a new Master Version and at its linguistic validation. Material and Methods: Three independent professional native Greek translators, two of them experts in Russian and one in English, translated the ACSS from Russian and American English into Greek. The second group of three translators translated each of the three Versions back into the original language to detect or correct any important discrepancies. These three Greek Versions were then used for linguistic validation. Results: The English to Greek translation reflected more the spoken language, the two Russian to Greek translations more the written, formal language. A total of 60 randomly selected females and 30 healthcare professionals was asked about their preferences and to comment on each of the three translations. Considering all comments the scientific committee (SC) developed the Greek consensus Version. For cognitive assessment additional 30 healthcare professionals and 30 females were asked to comment on the intelligibility of all items. Considering their comments the linguistically validated Greek study Version was established by the SC. Conclusion: The linguistically validated Greek Version of the ACSS can now be used for the clinical validation study.

  • Validation of the American English Acute Cystitis Symptom Score
    Antibiotics (Basel Switzerland), 2020
    Co-Authors: Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Florian M. E. Wagenlehner
    Abstract:

    The diagnosis of acute uncomplicated cystitis (UC) is usually based on clinical symptoms. The study aims to develop and validate the American-English Acute Cystitis Symptom Score (ACSS), a self-reporting questionnaire for diagnosis and patient-reported outcome in women with acute uncomplicated cystitis (UC). After certified translation into American-English and cognitive assessment, the clinical validation of the ACSS was performed embedded in a US phase-II trial. 167 female patients with typical symptoms of UC were included in the study following US Food and Drug Administration (FDA) guidance. At Day 1 (diagnosis), the mean (SD) sum score of the six ACSS typical symptoms reached 10.60 (2.51). Of 100 patients followed-up last time on Day 5 or 6 (End-of-treatment, EoT), 91 patients showed clinical success according to the favored ACSS criteria (sum score of typical symptoms 0.98 (1.94)). There was no correlation between the severity of symptoms on Day 1 or between clinical success rate at EoT and level of bacteriuria on Day 1. The American-English ACSS showed high predictive ability and responsiveness and excellent levels of reliability and validity. It can now be recommended as the new Master Version in clinical and epidemiological studies, in clinical practice, or for self-diagnosis of women with symptoms of UC.

  • Validation of the American English Version of The Acute Cystitis Symptom Score
    2020
    Co-Authors: Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Florian M. E. Wagenlehner
    Abstract:

    Background To develop and validate the American-English Version of the self-reporting Acute Cystitis Symptom Score (ACSS), a suitable tool for diagnosis and patient-reported outcome in female patients with acute uncomplicated cystitis (UC). Methods After certified translation into American-English and cognitive assessment, the clinical validation of the ACSS was performed as an embedded study in a US phase II trial (ClinicalTrials.gov Identifier: NCT03129295). Results A total of 167 female patients with typical symptoms of UC were included in the study following FDA guidance. At Day 1 (diagnosis) the mean(SD) sum score of the six ACSS typical symptoms reached 10.60(2.51). Of 100 patients followed-up last time on Day 5 or 6 (End-of-treatment, EoT), 91 patients showed clinical success according to the favoured ACSS criteria (sum score of typical symptoms 0.98(1.94)). There was no correlation between the severity of symptoms on Day 1 or between clinical success rate at EoT and level of bacteriuria on Day 1. Conclusion The American-English ACSS showed high predictive ability and responsiveness, and excellent levels of reliability and validity. It can now be recommended as the new Master Version in clinical and epidemiological studies, in clinical practice or for self-diagnosis of women with symptoms of UC.

Ahmad H. Alghadir - One of the best experts on this subject based on the ideXlab platform.

  • Postural stability in people with visual impairment.
    Brain and behavior, 2019
    Co-Authors: Ahmad H. Alghadir, Abdullah Z. Alotaibi, Zaheen A. Iqbal
    Abstract:

    Background The visual system enables the brain to assess information regarding the position of the body in space. Congenital or acquired blindness leads to the development of abnormal sensory-motor interactions that results in development of typical musculoskeletal deformities and gait patterns that cause disability. Diabetes and related complications are expected to increase exponentially in the next 10 years; thus, the number of people with visual impairment is expected to increase. However, there have been few studies regarding etio-pathogenesis of postural alteration and balance impairment in people with visual impairment; moreover, no previous study has investigated postural stability in this population. This study aimed to assess the center of gravity (COG) velocity in subjects with visual impairment and compared with that in sighted subjects. Methods Seventy male subjects, 20-40 years of age, participated in this study; they were divided into sighted (control) and visually impaired groups. COG velocity while standing on an unstable surface was measured using the NeuroCom® Balance Master Version 8.5.0. For the sighted group, data were recorded with eyes open and then with eyes closed. For the visually impaired group, no instructions were given with respect to eyes during data collection. Results Mean COG velocity was significantly higher in the visually impaired group than in the sighted group with eyes open. However, there was no difference in mean COG velocity between the visually impaired group and the sighted group with eyes closed. The difference in mean COG velocity between sighted subjects with eyes open and eyes closed was also significant. Mean COG velocity while standing on a foam surface varied among visually impaired subjects and sighted subjects with eyes open and closed. Conclusion This study showed that subjects with visual impairment, regardless of eye opening or closure, behave in the same manner as sighted subjects with eyes closed.

  • Effect of tongue position on postural stability during quiet standing in healthy young males.
    Somatosensory & motor research, 2015
    Co-Authors: Ahmad H. Alghadir, Hamayun Zafar, Zaheen A. Iqbal
    Abstract:

    AbstractBackground and aims: Role of the neck and jaw sensory motor system in control of body balance has been established. Tongue is an integral part of jaw sensory motor system and helps in execution of purposeful and precise motor tasks like eating, drinking and speaking. The purpose of this study was to evaluate the possible effects of tongue position on the postural control system.Materials and method: We compared the mean center of gravity (COG) velocity during quiet standing on an unstable surface with eyes closed during two test conditions: (i) with habitual jaw resting position and (ii) with instructed tongue positioned against the upper incisors. One hundred and sixteen normal healthy male subjects (average age 31.56 ± 8.51 years and height 170.86 ± 7.26 cm) participated in the study. Their COG velocity (deg/s) was measured using the NeuroCom® Balance Master Version 8.5.0 (Clackamas, OR, USA).Results and conclusions: The results show that COG velocity decreased significantly while tongue was pos...

  • Effect of chewing on postural stability during quiet standing in healthy young males
    Somatosensory & motor research, 2014
    Co-Authors: Ahmad H. Alghadir, Hamayun Zafar, Susan L. Whitney, Zaheen A. Iqbal
    Abstract:

    AbstractBackground and aims: There is an important role of the neck sensory motor system in control of body posture and balance, and it is reasonable to believe that the jaw sensory motor system can directly and indirectly influence the modulation of the postural control system. The purpose of this study was to evaluate possible effects of dynamic jaw position while chewing on the postural control system.Materials and methods: We compared the mean center of gravity (COG) velocity during quite standing on a foam surface with eyes closed during three test conditions: (i) with resting jaw position, (ii) with open jaw position, and (iii) while chewing standard bolus of chewing gum. One hundred and sixteen normal healthy male subjects (average age 31.56 ± 8.51 years; height 170.86 ± 7.26 cm) were recruited for the study. Their COG velocity (deg/s) was measured using the NeuroCom® Balance Master Version 8.5.0 (Clackamas, OR, USA).Statistical analysis: Data was tested by the Friedman test.Results and conclusions...

Jakhongir F. Alidjanov - One of the best experts on this subject based on the ideXlab platform.

  • Greek Version of the Acute Cystitis Symptom Score. Part I: Linguistic Validation
    2020
    Co-Authors: Konstantinos Stamatiou, Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Evangelia Samara, Florian M. E. Wagenlehner
    Abstract:

    Objective: The Acute Cystitis Symptom Score (ACSS) was developed and validated as a self-reporting questionnaire for diagnosing and monitoring acute, uncomplicated cystitis (AC) in female patients. The study aims at the translation of the ACSS into Greek from original Russian as a source and American English as a new Master Version and at its linguistic validation. Material and Methods: Three independent professional native Greek translators, two of them experts in Russian and one in English, translated the ACSS from Russian and American English into Greek. The second group of three translators translated each of the three Versions back into the original language to detect or correct any important discrepancies. These three Greek Versions were then used for linguistic validation. Results: The English to Greek translation reflected more the spoken language, the two Russian to Greek translations more the written, formal language. A total of 60 randomly selected females and 30 healthcare professionals was asked about their preferences and to comment on each of the three translations. Considering all comments the scientific committee (SC) developed the Greek consensus Version. For cognitive assessment additional 30 healthcare professionals and 30 females were asked to comment on the intelligibility of all items. Considering their comments the linguistically validated Greek study Version was established by the SC. Conclusion: The linguistically validated Greek Version of the ACSS can now be used for the clinical validation study.

  • Validation of the American English Acute Cystitis Symptom Score
    Antibiotics (Basel Switzerland), 2020
    Co-Authors: Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Florian M. E. Wagenlehner
    Abstract:

    The diagnosis of acute uncomplicated cystitis (UC) is usually based on clinical symptoms. The study aims to develop and validate the American-English Acute Cystitis Symptom Score (ACSS), a self-reporting questionnaire for diagnosis and patient-reported outcome in women with acute uncomplicated cystitis (UC). After certified translation into American-English and cognitive assessment, the clinical validation of the ACSS was performed embedded in a US phase-II trial. 167 female patients with typical symptoms of UC were included in the study following US Food and Drug Administration (FDA) guidance. At Day 1 (diagnosis), the mean (SD) sum score of the six ACSS typical symptoms reached 10.60 (2.51). Of 100 patients followed-up last time on Day 5 or 6 (End-of-treatment, EoT), 91 patients showed clinical success according to the favored ACSS criteria (sum score of typical symptoms 0.98 (1.94)). There was no correlation between the severity of symptoms on Day 1 or between clinical success rate at EoT and level of bacteriuria on Day 1. The American-English ACSS showed high predictive ability and responsiveness and excellent levels of reliability and validity. It can now be recommended as the new Master Version in clinical and epidemiological studies, in clinical practice, or for self-diagnosis of women with symptoms of UC.

  • Validation of the American English Version of The Acute Cystitis Symptom Score
    2020
    Co-Authors: Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Florian M. E. Wagenlehner
    Abstract:

    Background To develop and validate the American-English Version of the self-reporting Acute Cystitis Symptom Score (ACSS), a suitable tool for diagnosis and patient-reported outcome in female patients with acute uncomplicated cystitis (UC). Methods After certified translation into American-English and cognitive assessment, the clinical validation of the ACSS was performed as an embedded study in a US phase II trial (ClinicalTrials.gov Identifier: NCT03129295). Results A total of 167 female patients with typical symptoms of UC were included in the study following FDA guidance. At Day 1 (diagnosis) the mean(SD) sum score of the six ACSS typical symptoms reached 10.60(2.51). Of 100 patients followed-up last time on Day 5 or 6 (End-of-treatment, EoT), 91 patients showed clinical success according to the favoured ACSS criteria (sum score of typical symptoms 0.98(1.94)). There was no correlation between the severity of symptoms on Day 1 or between clinical success rate at EoT and level of bacteriuria on Day 1. Conclusion The American-English ACSS showed high predictive ability and responsiveness, and excellent levels of reliability and validity. It can now be recommended as the new Master Version in clinical and epidemiological studies, in clinical practice or for self-diagnosis of women with symptoms of UC.

Adrian Pilatz - One of the best experts on this subject based on the ideXlab platform.

  • Greek Version of the Acute Cystitis Symptom Score. Part I: Linguistic Validation
    2020
    Co-Authors: Konstantinos Stamatiou, Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Evangelia Samara, Florian M. E. Wagenlehner
    Abstract:

    Objective: The Acute Cystitis Symptom Score (ACSS) was developed and validated as a self-reporting questionnaire for diagnosing and monitoring acute, uncomplicated cystitis (AC) in female patients. The study aims at the translation of the ACSS into Greek from original Russian as a source and American English as a new Master Version and at its linguistic validation. Material and Methods: Three independent professional native Greek translators, two of them experts in Russian and one in English, translated the ACSS from Russian and American English into Greek. The second group of three translators translated each of the three Versions back into the original language to detect or correct any important discrepancies. These three Greek Versions were then used for linguistic validation. Results: The English to Greek translation reflected more the spoken language, the two Russian to Greek translations more the written, formal language. A total of 60 randomly selected females and 30 healthcare professionals was asked about their preferences and to comment on each of the three translations. Considering all comments the scientific committee (SC) developed the Greek consensus Version. For cognitive assessment additional 30 healthcare professionals and 30 females were asked to comment on the intelligibility of all items. Considering their comments the linguistically validated Greek study Version was established by the SC. Conclusion: The linguistically validated Greek Version of the ACSS can now be used for the clinical validation study.

  • Validation of the American English Acute Cystitis Symptom Score
    Antibiotics (Basel Switzerland), 2020
    Co-Authors: Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Florian M. E. Wagenlehner
    Abstract:

    The diagnosis of acute uncomplicated cystitis (UC) is usually based on clinical symptoms. The study aims to develop and validate the American-English Acute Cystitis Symptom Score (ACSS), a self-reporting questionnaire for diagnosis and patient-reported outcome in women with acute uncomplicated cystitis (UC). After certified translation into American-English and cognitive assessment, the clinical validation of the ACSS was performed embedded in a US phase-II trial. 167 female patients with typical symptoms of UC were included in the study following US Food and Drug Administration (FDA) guidance. At Day 1 (diagnosis), the mean (SD) sum score of the six ACSS typical symptoms reached 10.60 (2.51). Of 100 patients followed-up last time on Day 5 or 6 (End-of-treatment, EoT), 91 patients showed clinical success according to the favored ACSS criteria (sum score of typical symptoms 0.98 (1.94)). There was no correlation between the severity of symptoms on Day 1 or between clinical success rate at EoT and level of bacteriuria on Day 1. The American-English ACSS showed high predictive ability and responsiveness and excellent levels of reliability and validity. It can now be recommended as the new Master Version in clinical and epidemiological studies, in clinical practice, or for self-diagnosis of women with symptoms of UC.

  • Validation of the American English Version of The Acute Cystitis Symptom Score
    2020
    Co-Authors: Jakhongir F. Alidjanov, Kurt G. Naber, Adrian Pilatz, Florian M. E. Wagenlehner
    Abstract:

    Background To develop and validate the American-English Version of the self-reporting Acute Cystitis Symptom Score (ACSS), a suitable tool for diagnosis and patient-reported outcome in female patients with acute uncomplicated cystitis (UC). Methods After certified translation into American-English and cognitive assessment, the clinical validation of the ACSS was performed as an embedded study in a US phase II trial (ClinicalTrials.gov Identifier: NCT03129295). Results A total of 167 female patients with typical symptoms of UC were included in the study following FDA guidance. At Day 1 (diagnosis) the mean(SD) sum score of the six ACSS typical symptoms reached 10.60(2.51). Of 100 patients followed-up last time on Day 5 or 6 (End-of-treatment, EoT), 91 patients showed clinical success according to the favoured ACSS criteria (sum score of typical symptoms 0.98(1.94)). There was no correlation between the severity of symptoms on Day 1 or between clinical success rate at EoT and level of bacteriuria on Day 1. Conclusion The American-English ACSS showed high predictive ability and responsiveness, and excellent levels of reliability and validity. It can now be recommended as the new Master Version in clinical and epidemiological studies, in clinical practice or for self-diagnosis of women with symptoms of UC.