The Experts below are selected from a list of 11547 Experts worldwide ranked by ideXlab platform
Morten Kildal - One of the best experts on this subject based on the ideXlab platform.
-
importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis
Plastic and Reconstructive Surgery, 2004Co-Authors: Yangming Chang, Chiying Tsai, Morten KildalAbstract:Importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis.
-
importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis
Plastic and Reconstructive Surgery, 2004Co-Authors: Yangming Chang, Chiying Tsai, Morten Kildal, Fuchan WeiAbstract:Thirty patients with trismus resulting from betel nut chewing-induced oral submucous fibrosis were treated with either fibrotic tissue release only (group I) or fibrotic tissue release in combination with Masticatory Muscle myotomy and coronoidotomy (group II). The latter procedures were only performed in patients whose intraoperative interincisal distance remained less than 35 mm immediately after submucous fibrous tissue release. There were eight and 22 patients in groups I and II, respectively. In group I patients, the average intraoperative interincisal distance improved from 19.5 mm to 42 mm. In group II patients, the average intraoperative interincisal distance improved from 13.5 mm to 27 mm after fibrotic tissue release and further improved to 40 mm after Masticatory Muscle myotomy and coronoidotomy. At an average follow-up of 22.1 months (range, 7 to 70 months), the group I and II patients had an average interincisal distance of 41.5 mm (range, 35 to 50 mm) and 32.9 mm (range, 20 to 42 mm), respectively. These results demonstrate the efficacy of submucous fibrotic tissue release in treating trismus resulting from betel nut chewing-induced submucous fibrosis and confirm the role of additional Masticatory Muscle and coronoidotomy in treating its severe forms.
Yangming Chang - One of the best experts on this subject based on the ideXlab platform.
-
importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis
Plastic and Reconstructive Surgery, 2004Co-Authors: Yangming Chang, Chiying Tsai, Morten KildalAbstract:Importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis.
-
importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis
Plastic and Reconstructive Surgery, 2004Co-Authors: Yangming Chang, Chiying Tsai, Morten Kildal, Fuchan WeiAbstract:Thirty patients with trismus resulting from betel nut chewing-induced oral submucous fibrosis were treated with either fibrotic tissue release only (group I) or fibrotic tissue release in combination with Masticatory Muscle myotomy and coronoidotomy (group II). The latter procedures were only performed in patients whose intraoperative interincisal distance remained less than 35 mm immediately after submucous fibrous tissue release. There were eight and 22 patients in groups I and II, respectively. In group I patients, the average intraoperative interincisal distance improved from 19.5 mm to 42 mm. In group II patients, the average intraoperative interincisal distance improved from 13.5 mm to 27 mm after fibrotic tissue release and further improved to 40 mm after Masticatory Muscle myotomy and coronoidotomy. At an average follow-up of 22.1 months (range, 7 to 70 months), the group I and II patients had an average interincisal distance of 41.5 mm (range, 35 to 50 mm) and 32.9 mm (range, 20 to 42 mm), respectively. These results demonstrate the efficacy of submucous fibrotic tissue release in treating trismus resulting from betel nut chewing-induced submucous fibrosis and confirm the role of additional Masticatory Muscle and coronoidotomy in treating its severe forms.
Chiying Tsai - One of the best experts on this subject based on the ideXlab platform.
-
importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis
Plastic and Reconstructive Surgery, 2004Co-Authors: Yangming Chang, Chiying Tsai, Morten KildalAbstract:Importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis.
-
importance of coronoidotomy and Masticatory Muscle myotomy in surgical release of trismus caused by submucous fibrosis
Plastic and Reconstructive Surgery, 2004Co-Authors: Yangming Chang, Chiying Tsai, Morten Kildal, Fuchan WeiAbstract:Thirty patients with trismus resulting from betel nut chewing-induced oral submucous fibrosis were treated with either fibrotic tissue release only (group I) or fibrotic tissue release in combination with Masticatory Muscle myotomy and coronoidotomy (group II). The latter procedures were only performed in patients whose intraoperative interincisal distance remained less than 35 mm immediately after submucous fibrous tissue release. There were eight and 22 patients in groups I and II, respectively. In group I patients, the average intraoperative interincisal distance improved from 19.5 mm to 42 mm. In group II patients, the average intraoperative interincisal distance improved from 13.5 mm to 27 mm after fibrotic tissue release and further improved to 40 mm after Masticatory Muscle myotomy and coronoidotomy. At an average follow-up of 22.1 months (range, 7 to 70 months), the group I and II patients had an average interincisal distance of 41.5 mm (range, 35 to 50 mm) and 32.9 mm (range, 20 to 42 mm), respectively. These results demonstrate the efficacy of submucous fibrotic tissue release in treating trismus resulting from betel nut chewing-induced submucous fibrosis and confirm the role of additional Masticatory Muscle and coronoidotomy in treating its severe forms.
Robert Slater - One of the best experts on this subject based on the ideXlab platform.
-
painful unilateral temporalis Muscle enlargement reactive Masticatory Muscle hypertrophy
Head and Neck Pathology, 2014Co-Authors: Christos D Katsetos, Michael Bianchi, Fizza Jaffery, Sirma H Koutzaki, Mark D Zarella, Robert SlaterAbstract:An instance of isolated unilateral temporalis Muscle hypertrophy (reactive Masticatory Muscle hypertrophy with fiber type 1 predominance) confirmed by Muscle biopsy with histochemical fiber typing and image analysis in a 62 year-old man is reported. The patient presented with bruxism and a painful swelling of the temple. Absence of asymmetry or other abnormalities of the craniofacial skeleton was confirmed by magnetic resonance imaging and cephalometric analyses. The patient achieved symptomatic improvement only after undergoing botulinum toxin injections. Muscle biopsy is key in the diagnosis of reactive Masticatory Muscle hypertrophy and its distinction from Masticatory Muscle myopathy (hypertrophic branchial myopathy) and other non-reactive causes of painful asymmetric temporalis Muscle enlargement.
Tsuyoshi Sato - One of the best experts on this subject based on the ideXlab platform.
-
possible association of oestrogen and cryba4 with Masticatory Muscle tendon aponeurosis hyperplasia
Oral Diseases, 2019Co-Authors: Naoki Hayashi, Tsuyoshi Sato, Shoichiro Kokabu, Michihiko Usui, Megumi Yumoto, Eiji Ikami, Y Sakamoto, Akira Nifuji, Tadayoshi HayataAbstract:OBJECTIVE: Masticatory Muscle tendon-aponeurosis hyperplasia, which is associated with limited mouth opening, progresses very slowly from adolescence. The prevalence rates of this disease are higher among women than among men, suggesting oestrogen involvement. As parafunctional habits are frequently observed, mechanical stress is likely involved in the pathogenesis and advancement of this disease. To elucidate the pathological condition, we examined the effect of oestrogen on tenocyte function and the relationship between mechanical stress and crystallin beta A4 (Cryba4), using murine TT-D6 tenocytes. MATERIALS AND METHODS: Cell proliferation assays, RT-PCR, real-time RT-PCR, Western blot analysis and mechanical loading experiments were performed. RESULTS: The physiological dose of oestrogen increased the levels of scleraxis and tenomodulin in TT-D6 tenocytes. In contrast, forced expression of Cryba4 inhibited scleraxis expression in these cells. Surprisingly, oestrogen significantly promoted cell differentiation in the Cryba4-overexpressing TT-D6 tenocytes. Moreover, tensile force induced Cryba4 expression in these tendon cells. CONCLUSION: Oestrogen and Cryba4 may be associated with the progression of Masticatory Muscle tendon-aponeurosis hyperplasia.
-
Masticatory Muscle tendon aponeurosis hyperplasia exhibits heterotopic calcification in tendons
Oral Diseases, 2014Co-Authors: Tsuyoshi Sato, Naoko Hori, Norimichi Nakamoto, M Akita, Tetsuya YodaAbstract:Objective Masticatory Muscle tendon-aponeurosis hyperplasia is a new disease entity associated with limited mouth opening. In this study, we analyzed the microstructural characteristics of Muscles and tendons in Masticatory Muscle tendon-aponeurosis hyperplasia by electron microscopy and energy-dispersive X-ray analysis to determine the elemental composition. Methods Histological analysis was performed to detect the calcification. Transmission electron microscopy and scanning electron microscopy were conducted to clarify the microstructural characteristics of Muscles and tendons. Energy-dispersive X-ray microanalysis was performed to identify the distribution of elements. Results Mineralized nodules were observed in tendon tissues of Masticatory Muscle tendon-aponeurosis hyperplasia as compared with facial deformity. Electron microscopy revealed that the Muscle and tendon tissues in Masticatory Muscle tendon-aponeurosis hyperplasia showed degenerative changes and distinctive histological findings as compared with tissues in facial deformity. We found that Ca, P, and Si were detected only in Masticatory Muscle tendon-aponeurosis hyperplasia. Conclusion We demonstrated that Masticatory Muscle tendon-aponeurosis hyperplasia exhibits heterotopic calcification in tendon tissues.
-
proteomics based identification of novel proteins in temporal tendons of patients with Masticatory Muscle tendon aponeurosis hyperplasia
International Journal of Oral and Maxillofacial Surgery, 2014Co-Authors: Aya Nakamoto, Tsuyoshi Sato, Norimichi Nakamoto, Michihiko Usui, Yuichiro Enoki, Dai Chida, N Hirosawa, Shu Takeda, T Nagai, A SasakiAbstract:Abstract Masticatory Muscle tendon–aponeurosis hyperplasia (MMTAH) is a new disease associated with limited mouth opening that is often misdiagnosed as a temporomandibular disorder; subsequently, patients are mistakenly treated with irreversible operations. Due to the poor presentation and characterization of symptoms, the underlying pathological conditions remain unclear. We have previously conducted a proteomic analysis of tendons derived from one MMTAH subject and one facial deformity subject using two-dimensional fluorescence difference gel electrophoresis and liquid chromatography coupled with tandem mass spectrometry. However, the results were obtained for only one subject. The aim of the present study was to confirm the expression of specific molecules in tendon tissues from multiple subjects with MMTAH by applying two-dimensional polyacrylamide gel electrophoresis with matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Of the 19 proteins identified in tendons from both MMTAH and facial deformity patients, fibrinogen fragment D and beta-crystallin A4 were up-regulated, whereas myosin light chain 4 was down-regulated in MMTAH. We also found fibrinogen to be expressed robustly in tendon tissues of MMTAH patients. Our data provide the possibility that the distinctive expression of these novel proteins is associated with the pathology of MMTAH.
-
proteomic analysis of Masticatory Muscle tendon aponeurosis hyperplasia a preliminary study using a 2d dige system
Journal of Oral and Maxillofacial Surgery Medicine and Pathology, 2012Co-Authors: Tsuyoshi Sato, Naoko Hori, Norimichi Nakamoto, Aya Nakamoto, Yuichiro Enoki, Yousuke Fukushima, Yasuaki Sakata, Hidenori Yamanaka, Dai Chida, Tetsuya YodaAbstract:Abstract Masticatory Muscle tendon–aponeurosis hyperplasia (MATAPHY) exhibits hyperplasia on tendon and aponeurosis of the Masticatory Muscles histopathologically. This disease is characterized by a palpable dense band of the anterior border of the masseter Muscle on maximum mouth opening, strike root appearance on MR imaging and square mandible configuration. However, the common useful diagnostic markers of this disease are still unknown. Here we performed a preliminary study to identify potential therapeutic targets and diagnostic markers that may indicate disease progression of MATAPHY using a proteomic analysis method, two-dimensional fluorescence difference gel electrophoresis and liquid chromatography coupled with tandem mass spectrometry. We have found that myosin regulatory light chain 2 and myosin regulatory light chain 3 were down-regulated in MATAPHY. This result is consistent with the observation that Muscle tissues showed atrophic changes. We have also demonstrated that aortic smooth Muscle actin was down-regulated in MATAPHY, suggesting that this down-regulation is due to decreasing in Muscle tissues that blood vessels are abundant and increasing in tendon tissues that blood vessels are exiguous. Furthermore, collagen alpha-1(VI) chain (COL6A1) was up-regulated in MATAPHY. COL6A1, which is essential for tendon fibrillogenesis, expressed in the Masticatory Muscle, indicating that tendon-aponeurosis hyperplasia is due to the overexpression of COL6A1. Facial deformity, which we choose as a control in this study, is sometimes congenital and may be complicated with deficiency of the skeletal proteins. Although this report has some limitations, this is the first report to describe the relationship between the variation of specific molecules and histopathological observation in MATAPHY.
-
long term results of surgical therapy for Masticatory Muscle tendon aponeurosis hyperplasia accompanied by limited mouth opening
International Journal of Oral and Maxillofacial Surgery, 2009Co-Authors: Tetsuya Yoda, Tsuyoshi Sato, I Sakamoto, Yasuhisa Tomaru, Ken Omura, Noriko Hatano, Tsuyoshi Takato, Yoshimasa IshiiAbstract:Abstract Masticatory Muscle tendon-aponeurosis hyperplasia is a new disease entity characterized by limited mouth opening due to contracture of the Masticatory Muscles, resulting from hyperplasia of tendons and aponeuroses. In the case of masseter Muscle type, the face displays a square mandible configuration. Pharmacotherapy, occlusal splints and physical therapy are ineffective. This study evaluated the long-term results of aponeurectomy of the masseter Muscle with coronoidectomy to release the temporal Muscle tendon. The subjects were 10 patients who underwent surgery between 2000 and 2005. Mean maximum mouth opening before surgery was 21.8 mm (range 17–29 mm). All patients received bilateral aponeurectomy of the masseter Muscle and coronoidectomy. Three patients additionally underwent bilateral anglectomy for esthetic reasons. After discharge, one patient did not return to the hospital. Data from the other nine patients were analyzed. The mean duration of follow-up was 4 years. At final follow-up, the maximum mouth opening was >44 mm in four patients, 40–44 mm in three patients, and 35–39 mm in two patients. Overall satisfaction was excellent or good in all patients.
