The Experts below are selected from a list of 519552 Experts worldwide ranked by ideXlab platform
Xavier Rognon - One of the best experts on this subject based on the ideXlab platform.
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genetic diversity of dog breeds within breed diversity comparing genealogical and molecular data
Animal Genetics, 2009Co-Authors: Gregoire Leroy, Etienne Verrier, J C Meriaux, Xavier RognonAbstract:Summary The genetic diversity of 61 dog breeds raised in France was investigated. Genealogical analyses were performed on the pedigree file of the French kennel club. A total of 1514 dogs were also genotyped using 21 microsatellite markers. For animals born from 2001 to 2005, the average coefficient of inbreeding ranged from 0.2% to 8.8% and the effective number of ancestors ranged from 9 to 209, according to the breed. The Mean value of heterozygosity was 0.62 over all breeds (range 0.37‐0.77). At the breed level, few Correlations were found between genealogical and molecular parameters. Kinship coefficients and individual similarity estimators were, however, significantly correlated, with the best Mean Correlation being found for the Lynch & Ritland estimator (r = 0.43). According to both approaches, it was concluded that special efforts should be made to maintain diversity for three breeds,
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genetic diversity of dog breeds within breed diversity comparing genealogical and molecular data
Animal Genetics, 2009Co-Authors: Gregoire Leroy, Etienne Verrier, J C Meriaux, Xavier RognonAbstract:The genetic diversity of 61 dog breeds raised in France was investigated. Genealogical analyses were performed on the pedigree file of the French kennel club. A total of 1514 dogs were also genotyped using 21 microsatellite markers. For animals born from 2001 to 2005, the average coefficient of inbreeding ranged from 0.2% to 8.8% and the effective number of ancestors ranged from 9 to 209, according to the breed. The Mean value of heterozygosity was 0.62 over all breeds (range 0.37-0.77). At the breed level, few Correlations were found between genealogical and molecular parameters. Kinship coefficients and individual similarity estimators were, however, significantly correlated, with the best Mean Correlation being found for the Lynch & Ritland estimator (r = 0.43). According to both approaches, it was concluded that special efforts should be made to maintain diversity for three breeds, namely the Berger des Pyrenees, Braque Saint-Germain and Bull Terrier.
David J. Schlegel - One of the best experts on this subject based on the ideXlab platform.
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the velocity dispersion function of early type galaxies
The Astrophysical Journal, 2003Co-Authors: Ravi K Sheth, Mariangela Bernardi, Paul L Schechter, Scott Burles, Daniel J Eisenstein, Douglas P Finkbeiner, J Frieman, Robert H Lupton, David J. SchlegelAbstract:The distribution of early-type galaxy velocity dispersions, (?), is measured using a sample drawn from the Sloan Digital Sky Survey database. Its shape differs significantly from that obtained by simply using the Mean Correlation between luminosity L and velocity dispersion ? to transform the luminosity function into a velocity function: ignoring the scatter around the Mean ?-L relation is a bad approximation. An estimate of the contribution from late-type galaxies is also made, which suggests that (?) is dominated by early-type galaxies at velocities larger than ~200 km s-1.
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the velocity dispersion function of early type galaxies
arXiv: Astrophysics, 2003Co-Authors: Ravi K Sheth, Mariangela Bernardi, Paul L Schechter, Scott Burles, Daniel J Eisenstein, Douglas P Finkbeiner, J Frieman, Robert H Lupton, David W Hogg, David J. SchlegelAbstract:The distribution of early-type galaxy velocity dispersions, phi(sigma), is measured using a sample drawn from the SDSS database. Its shape differs significantly from that which one obtains by simply using the Mean Correlation between luminosity, L, and velocity dispersion, sigma, to transform the luminosity function into a velocity function: ignoring the scatter around the Mean sigma-L relation is a bad approximation. An estimate of the contribution from late-type galaxies is also made, which suggests that phi(sigma) is dominated by early-type galaxies at velocities larger than ~ 200 km/s.
Douglas P Finkbeiner - One of the best experts on this subject based on the ideXlab platform.
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the velocity dispersion function of early type galaxies
The Astrophysical Journal, 2003Co-Authors: Ravi K Sheth, Mariangela Bernardi, Paul L Schechter, Scott Burles, Daniel J Eisenstein, Douglas P Finkbeiner, J Frieman, Robert H Lupton, David J. SchlegelAbstract:The distribution of early-type galaxy velocity dispersions, (?), is measured using a sample drawn from the Sloan Digital Sky Survey database. Its shape differs significantly from that obtained by simply using the Mean Correlation between luminosity L and velocity dispersion ? to transform the luminosity function into a velocity function: ignoring the scatter around the Mean ?-L relation is a bad approximation. An estimate of the contribution from late-type galaxies is also made, which suggests that (?) is dominated by early-type galaxies at velocities larger than ~200 km s-1.
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the velocity dispersion function of early type galaxies
arXiv: Astrophysics, 2003Co-Authors: Ravi K Sheth, Mariangela Bernardi, Paul L Schechter, Scott Burles, Daniel J Eisenstein, Douglas P Finkbeiner, J Frieman, Robert H Lupton, David W Hogg, David J. SchlegelAbstract:The distribution of early-type galaxy velocity dispersions, phi(sigma), is measured using a sample drawn from the SDSS database. Its shape differs significantly from that which one obtains by simply using the Mean Correlation between luminosity, L, and velocity dispersion, sigma, to transform the luminosity function into a velocity function: ignoring the scatter around the Mean sigma-L relation is a bad approximation. An estimate of the contribution from late-type galaxies is also made, which suggests that phi(sigma) is dominated by early-type galaxies at velocities larger than ~ 200 km/s.
Gregoire Leroy - One of the best experts on this subject based on the ideXlab platform.
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genetic diversity of dog breeds within breed diversity comparing genealogical and molecular data
Animal Genetics, 2009Co-Authors: Gregoire Leroy, Etienne Verrier, J C Meriaux, Xavier RognonAbstract:Summary The genetic diversity of 61 dog breeds raised in France was investigated. Genealogical analyses were performed on the pedigree file of the French kennel club. A total of 1514 dogs were also genotyped using 21 microsatellite markers. For animals born from 2001 to 2005, the average coefficient of inbreeding ranged from 0.2% to 8.8% and the effective number of ancestors ranged from 9 to 209, according to the breed. The Mean value of heterozygosity was 0.62 over all breeds (range 0.37‐0.77). At the breed level, few Correlations were found between genealogical and molecular parameters. Kinship coefficients and individual similarity estimators were, however, significantly correlated, with the best Mean Correlation being found for the Lynch & Ritland estimator (r = 0.43). According to both approaches, it was concluded that special efforts should be made to maintain diversity for three breeds,
-
genetic diversity of dog breeds within breed diversity comparing genealogical and molecular data
Animal Genetics, 2009Co-Authors: Gregoire Leroy, Etienne Verrier, J C Meriaux, Xavier RognonAbstract:The genetic diversity of 61 dog breeds raised in France was investigated. Genealogical analyses were performed on the pedigree file of the French kennel club. A total of 1514 dogs were also genotyped using 21 microsatellite markers. For animals born from 2001 to 2005, the average coefficient of inbreeding ranged from 0.2% to 8.8% and the effective number of ancestors ranged from 9 to 209, according to the breed. The Mean value of heterozygosity was 0.62 over all breeds (range 0.37-0.77). At the breed level, few Correlations were found between genealogical and molecular parameters. Kinship coefficients and individual similarity estimators were, however, significantly correlated, with the best Mean Correlation being found for the Lynch & Ritland estimator (r = 0.43). According to both approaches, it was concluded that special efforts should be made to maintain diversity for three breeds, namely the Berger des Pyrenees, Braque Saint-Germain and Bull Terrier.
Mostafa A Shehata - One of the best experts on this subject based on the ideXlab platform.
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comparative study between univariate spectrophotometry and multivariate calibration as analytical tools for simultaneous quantitation of moexipril and hydrochlorothiazide
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014Co-Authors: Shereen M Tawakkol, Maha Farouk, Omar Abd Elaziz, A Hemdan, Mostafa A ShehataAbstract:Three simple, accurate, reproducible, and selective methods have been developed and subsequently validated for the simultaneous determination of Moexipril (MOX) and Hydrochlorothiazide (HCTZ) in pharmaceutical dosage form. The first method is the new extended ratio subtraction method (EXRSM) coupled to ratio subtraction method (RSM) for determination of both drugs in commercial dosage form. The second and third methods are multivariate calibration which include Principal Component Regression (PCR) and Partial Least Squares (PLSs). A detailed validation of the methods was performed following the ICH guidelines and the standard curves were found to be linear in the range of 10–60 and 2–30 for MOX and HCTZ in EXRSM method, respectively, with well accepted Mean Correlation coefficient for each analyte. The intra-day and inter-day precision and accuracy results were well within the acceptable limits.
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comparative study between univariate spectrophotometry and multivariate calibration as analytical tools for quantitation of benazepril alone and in combination with amlodipine
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014Co-Authors: Maha Farouk, Shereen M Tawakkol, Omar Abd Elaziz, A Hemdan, Mostafa A ShehataAbstract:Abstract Four simple, accurate, reproducible, and selective methods have been developed and subsequently validated for the determination of Benazepril (BENZ) alone and in combination with Amlodipine (AML) in pharmaceutical dosage form. The first method is pH induced difference spectrophotometry, where BENZ can be measured in presence of AML as it showed maximum absorption at 237 nm and 241 nm in 0.1 N HCl and 0.1 N NaOH, respectively, while AML has no wavelength shift in both solvents. The second method is the new Extended Ratio Subtraction Method (EXRSM) coupled to Ratio Subtraction Method (RSM) for determination of both drugs in commercial dosage form. The third and fourth methods are multivariate calibration which include Principal Component Regression (PCR) and Partial Least Squares (PLSs). A detailed validation of the methods was performed following the ICH guidelines and the standard curves were found to be linear in the range of 2–30 μg/mL for BENZ in difference and extended ratio subtraction spectrophotometric method, and 5–30 for AML in EXRSM method, with well accepted Mean Correlation coefficient for each analyte. The intra-day and inter-day precision and accuracy results were well within the acceptable limits.
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comparative study between univariate spectrophotometry and multivariate calibration as analytical tools for quantitation of benazepril alone and in combination with amlodipine
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014Co-Authors: Maha Farouk, Shereen M Tawakkol, Omar Abd Elaziz, A Hemdan, Mostafa A ShehataAbstract:Abstract Four simple, accurate, reproducible, and selective methods have been developed and subsequently validated for the determination of Benazepril (BENZ) alone and in combination with Amlodipine (AML) in pharmaceutical dosage form. The first method is pH induced difference spectrophotometry, where BENZ can be measured in presence of AML as it showed maximum absorption at 237 nm and 241 nm in 0.1 N HCl and 0.1 N NaOH, respectively, while AML has no wavelength shift in both solvents. The second method is the new Extended Ratio Subtraction Method (EXRSM) coupled to Ratio Subtraction Method (RSM) for determination of both drugs in commercial dosage form. The third and fourth methods are multivariate calibration which include Principal Component Regression (PCR) and Partial Least Squares (PLSs). A detailed validation of the methods was performed following the ICH guidelines and the standard curves were found to be linear in the range of 2–30 μg/mL for BENZ in difference and extended ratio subtraction spectrophotometric method, and 5–30 for AML in EXRSM method, with well accepted Mean Correlation coefficient for each analyte. The intra-day and inter-day precision and accuracy results were well within the acceptable limits.
