The Experts below are selected from a list of 18 Experts worldwide ranked by ideXlab platform
Cathy Mead - One of the best experts on this subject based on the ideXlab platform.
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An outbreak of Measles in a highly immunised population: immunisation status and Vaccine efficacy
Australian journal of public health, 2010Co-Authors: Ana Herceg, Irene Passaris, Cathy MeadAbstract:: An outbreak of 18 cases of Measles in a primary school in the Australian Capital Territory in August and September 1993 provided the opportunity to study Measles immunisation status and Measles Vaccine efficacy. Parents of 384 (78 per cent) of 491 children answered a questionnaire on recent illness consistent with Measles and Measles immunisation. Parents transcribed details of Measles immunisation from the personal health record of the child to the questionnaire. Thirty-three per cent of cases and 3.4 per cent of the other children had not been immunised. Overall, 95 per cent of children had been immunised. The efficacy for all Measles Vaccines was estimated to be 90 per cent (95 per cent confidence interval (CI) 75 to 96) and for Measles-Mumps Vaccine 87 per cent (CI 70 to 95). All of the immunised cases had received Measles-Mumps Vaccine. There was no increased risk of Measles infection in those who had been immunised at under 15 months of age compared with those immunised at 15 months or older, or in those who could not provide a date of immunisation compared with those who could. None of the children who had received two doses of Vaccine caught Measles. The date of immunisation was provided by 65 per cent of the respondents who said their children had been immunised. Asking parents to provide this date instead of viewing the health record is a less expensive way of assessing immunisation status but this method needs to be evaluated. Measles outbreaks still occur in highly immunised populations when Vaccine efficacy appears to be acceptable.
Fang Wei-hua - One of the best experts on this subject based on the ideXlab platform.
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Studies on Safety and Immune Efficacy of Domestic Live Attenuated Lyophilized Measles-Mumps Combined Vaccine
Chinese Journal of Vaccines and Immunization, 2001Co-Authors: Fang Wei-huaAbstract:The clinical reaction and immune effect of the lyophilized live attenuated Measles-Mumps combined Vaccine firstly produced in China were observed in Jiangxi Province in 1998-1999. Infants ≥8 months old with Measles and Mumps antibodies negative were selected to vaccinate MM Vaccine, other infants of same condition were vaccinated with Measles Vaccine, Mumps Vaccine and imported Measles-Mumps-rubella (MMR) Vaccine separately as controls. Antibodies of Measles and Mumps were tested by micro-neutralization and HI tests. The results showed that 136 infants after vaccinated with Measles-Mumps Vaccine, had no signs of rashes and swelling of parotid gland, fever were graded by low (15.44%), medium (5.88%) and no high fever was seen. The positive seroconversion rates and GMTs of Mumps and Measles were 81.82%~86.00%, 1∶3.88~1∶6.79 and 95.12%~100%, 1∶63.79~1∶76.11 respectively, that were similar to those of the controls vaccinated separately with Measles, Mumps and MMR Vaccines. The safety and immune efficacy of domestic lyophilized Measles-Mumps combined Vaccine is satisfactory and it may be popularized.
Ana Herceg - One of the best experts on this subject based on the ideXlab platform.
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An outbreak of Measles in a highly immunised population: immunisation status and Vaccine efficacy
Australian journal of public health, 2010Co-Authors: Ana Herceg, Irene Passaris, Cathy MeadAbstract:: An outbreak of 18 cases of Measles in a primary school in the Australian Capital Territory in August and September 1993 provided the opportunity to study Measles immunisation status and Measles Vaccine efficacy. Parents of 384 (78 per cent) of 491 children answered a questionnaire on recent illness consistent with Measles and Measles immunisation. Parents transcribed details of Measles immunisation from the personal health record of the child to the questionnaire. Thirty-three per cent of cases and 3.4 per cent of the other children had not been immunised. Overall, 95 per cent of children had been immunised. The efficacy for all Measles Vaccines was estimated to be 90 per cent (95 per cent confidence interval (CI) 75 to 96) and for Measles-Mumps Vaccine 87 per cent (CI 70 to 95). All of the immunised cases had received Measles-Mumps Vaccine. There was no increased risk of Measles infection in those who had been immunised at under 15 months of age compared with those immunised at 15 months or older, or in those who could not provide a date of immunisation compared with those who could. None of the children who had received two doses of Vaccine caught Measles. The date of immunisation was provided by 65 per cent of the respondents who said their children had been immunised. Asking parents to provide this date instead of viewing the health record is a less expensive way of assessing immunisation status but this method needs to be evaluated. Measles outbreaks still occur in highly immunised populations when Vaccine efficacy appears to be acceptable.
Irene Passaris - One of the best experts on this subject based on the ideXlab platform.
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An outbreak of Measles in a highly immunised population: immunisation status and Vaccine efficacy
Australian journal of public health, 2010Co-Authors: Ana Herceg, Irene Passaris, Cathy MeadAbstract:: An outbreak of 18 cases of Measles in a primary school in the Australian Capital Territory in August and September 1993 provided the opportunity to study Measles immunisation status and Measles Vaccine efficacy. Parents of 384 (78 per cent) of 491 children answered a questionnaire on recent illness consistent with Measles and Measles immunisation. Parents transcribed details of Measles immunisation from the personal health record of the child to the questionnaire. Thirty-three per cent of cases and 3.4 per cent of the other children had not been immunised. Overall, 95 per cent of children had been immunised. The efficacy for all Measles Vaccines was estimated to be 90 per cent (95 per cent confidence interval (CI) 75 to 96) and for Measles-Mumps Vaccine 87 per cent (CI 70 to 95). All of the immunised cases had received Measles-Mumps Vaccine. There was no increased risk of Measles infection in those who had been immunised at under 15 months of age compared with those immunised at 15 months or older, or in those who could not provide a date of immunisation compared with those who could. None of the children who had received two doses of Vaccine caught Measles. The date of immunisation was provided by 65 per cent of the respondents who said their children had been immunised. Asking parents to provide this date instead of viewing the health record is a less expensive way of assessing immunisation status but this method needs to be evaluated. Measles outbreaks still occur in highly immunised populations when Vaccine efficacy appears to be acceptable.
H. Woollett - One of the best experts on this subject based on the ideXlab platform.
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School health nurse interventions to increaseimmunisation uptake in school entrants
Public health, 1995Co-Authors: M.j. Ferson, G. Fitzsimmons, D. Christie, H. WoollettAbstract:Abstract In New South Wales, health screening of school entrants provides the only mechanism for routine monitoring of immunisation uptake in children. School health nurses are in the best position to improve the compliance with immunisation at this age. We compared two interventions to be used by the nurses to increase immunisation uptake in school entrants who reported missing either the Measles-Mumps Vaccine and/or the pre-school diphtheria-tetanus toxoid and oral polio Vaccine boosters. Parents in the passive intervention group were sent a letter and leaflet encouraging immunisation; the active intervention group received a telephone reminder from the nurse in addition to the written materials. Both groups were followed up at a later date to assess final immunisation outcome. Of 817 children screened, 88.2% had been immunised against Measles and 73.6% had received the booster; 239 children were randomised to the two interventions. Excluding children lost to follow up and those fully immunised at the start of the study, 20 (37%) of 54 were immunised following the passive intervention, and 35 (71%) out of 49 following the active intervention ( P =0.001). Receipt of the letter and leaflet was associated with an increased uptake of booster vaccination ( P =0.036). The active intervention required 14.7 telephone calls and 1.6 uses of the interpreter service per completed immunisation. The passive intervention resulted in worthwhile increases in immunisation rate with minimum cost. A greater improvement in immunisation outcome was achieved by the active intervention, but its use was labour intensive and may only be warranted if high immunisation rates in this age-group are given priority.