The Experts below are selected from a list of 203568 Experts worldwide ranked by ideXlab platform
Mi Jung Kwon - One of the best experts on this subject based on the ideXlab platform.
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invasion Depth Measured in millimeters is a predictor of survival in patients with distal bile duct cancer decision tree approach
World Journal of Surgery, 2017Co-Authors: Kyuengwhan Min, Dong Hoon Kim, Byoung Kwan Son, Eun Kyung Kim, Sang Bong Ahn, Seong Hwan Kim, Young Sook Park, Jinwon Seo, Ho Young Kim, Mi Jung KwonAbstract:Background AJCC staging system is unreliable for predicting survival in distal bile duct (DBD) cancer patients, due to inter-observer variation. Measured Depth of invasion (DOI) is suggested to be more accurate to predict patients’ clinical outcome in extra-hepatic cholangiocarcinomas, but its significance in DBD cancer and cutoff values are still debatable. This study aimed to identify the optimal cutoff value of DOI in relation to prognosis in DBD cancer patients.
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invasion Depth Measured in millimeters is a predictor of survival in patients with distal bile duct cancer decision tree approach
World Journal of Surgery, 2017Co-Authors: Kyuengwhan Min, Dong Hoon Kim, Byoung Kwan Son, Eun Kyung Kim, Sang Bong Ahn, Seong Hwan Kim, Young Sook Park, Jinwon Seo, Ho Young Kim, Mi Jung KwonAbstract:AJCC staging system is unreliable for predicting survival in distal bile duct (DBD) cancer patients, due to inter-observer variation. Measured Depth of invasion (DOI) is suggested to be more accurate to predict patients’ clinical outcome in extra-hepatic cholangiocarcinomas, but its significance in DBD cancer and cutoff values are still debatable. This study aimed to identify the optimal cutoff value of DOI in relation to prognosis in DBD cancer patients. Data of 179 patients with DBD adenocarcinoma treated in three institutions were investigated. Under microscopic review, DOI was Measured. The relationships between the clinicopathological parameters and the groups based on DOI (≤3; 3–10; >10 mm) were evaluated, and the survival times of each group based on DOI and T classification were compared. Deeply invading tumors exhibited a greater tendency toward the infiltrative type, high histological grade, AJCC stage, and pancreatic, duodenal, lymphovascular and perineural invasion. The Measured DOI was significantly correlated with worse relapse-free and overall survival (all p < 0.05). In multivariate analyses, the DOI remained as one of the prognostic factors (all p < 0.05), while T classification was not a significant prognostic factor. The new prognostic models (low, intermediate, and high risk) that applied DOI and nodal metastasis showed significant difference in recurrence and survival rate (all p < 0.05). On the basis of the proposed cutoff value, the DOI could be clear and meaningful, overcoming the vagueness of the T classification for predicting clinical outcomes in patients with DBD carcinoma.
Laurence N Warr - One of the best experts on this subject based on the ideXlab platform.
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nanocoatings of clay and creep of the san andreas fault at parkfield california
Geology, 2010Co-Authors: Anja M Schleicher, B A Van Der Pluijm, Laurence N WarrAbstract:Mudrock samples were investigated from two fault zones at ∼3066 m and ∼3296 m Measured Depth (MD) located outside and within the main damage zone of the San Andreas Fault Observatory at Depth (SAFOD) drillhole at Parkfield, California. All studied fault rocks show features typical of those reported across creep zones with variably spaced and interconnected networks of polished displacement surfaces coated by abundant polished films and occasional striations. Electron microscopy and X-ray diffraction study of the surfaces reveal the occurrence of neocrystallized thin film clay coatings containing illite-smectite (I-S) and chlorite-smectite (C-S) minerals. 40 Ar/ 39 Ar dating of the illitic mix-layered coatings demonstrated Miocene to Pliocene crystallization and revealed an older fault strand (8 ± 1.3 Ma) at 3066 m MD, and a probably younger fault strand (4 ± 4.9 Ma) at 3296 m MD. Today, the younger strand is the site of active creep behavior, reflecting a possible (re)activation of these clay-weakened zones. We propose that the majority of slow fault creep is controlled by the high density of thin (
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constraints on mineralization fluid rock interaction and mass transfer during faulting at 2 3 km Depth from the safod drill hole
Journal of Geophysical Research, 2009Co-Authors: Anja M Schleicher, Sara N Tourscher, Ben A Van Der Pluijm, Laurence N WarrAbstract:[1] Mineralogical and geochemical changes in mudrock cuttings from two segments of the San Andreas Fault Observatory at Depth (SAFOD) drill hole (3066–3169 and 3292–3368 m Measured Depth) are analyzed in this study. Bulk rock samples and hand-picked fault-related grains characterized by polished surfaces and slickensides were investigated by X-ray diffraction, electron microscopy, and geochemical analysis. The elemental changes in fault-related grains along the sampled San Andreas Fault are attributed to dissolution of detrital grains (particularly feldspar and quartz) and local precipitation of illite-smectite and/or chlorite-smectite mixed layers in fractures and veins. Assuming ZrO2 and TiO2 to be immobile elements, systematic differences in element concentrations show that most of the elements are depleted in the fault-related grains compared to the wall rock lithology. Calculated mass loss between the bulk rock and picked fault rock ranges from 17 to 58% with a greater mass transport in the shallow trace of the sampled fault that marks the upper limit the fault core. The relatively large amount of element transport at temperatures of ∼110–114°C recorded throughout the core requires extensive fluid circulation during faulting. Whereas dissolution/precipitation may be partly induced by the disequilibrium between fluids and rocks during diagenetic processes, stress-induced dissolution at grain contacts is proposed as the main mechanism for extensive mineral transformation in the fault rocks and localization of neomineralization along grain interface slip surfaces.
Anja M Schleicher - One of the best experts on this subject based on the ideXlab platform.
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nanocoatings of clay and creep of the san andreas fault at parkfield california
Geology, 2010Co-Authors: Anja M Schleicher, B A Van Der Pluijm, Laurence N WarrAbstract:Mudrock samples were investigated from two fault zones at ∼3066 m and ∼3296 m Measured Depth (MD) located outside and within the main damage zone of the San Andreas Fault Observatory at Depth (SAFOD) drillhole at Parkfield, California. All studied fault rocks show features typical of those reported across creep zones with variably spaced and interconnected networks of polished displacement surfaces coated by abundant polished films and occasional striations. Electron microscopy and X-ray diffraction study of the surfaces reveal the occurrence of neocrystallized thin film clay coatings containing illite-smectite (I-S) and chlorite-smectite (C-S) minerals. 40 Ar/ 39 Ar dating of the illitic mix-layered coatings demonstrated Miocene to Pliocene crystallization and revealed an older fault strand (8 ± 1.3 Ma) at 3066 m MD, and a probably younger fault strand (4 ± 4.9 Ma) at 3296 m MD. Today, the younger strand is the site of active creep behavior, reflecting a possible (re)activation of these clay-weakened zones. We propose that the majority of slow fault creep is controlled by the high density of thin (
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constraints on mineralization fluid rock interaction and mass transfer during faulting at 2 3 km Depth from the safod drill hole
Journal of Geophysical Research, 2009Co-Authors: Anja M Schleicher, Sara N Tourscher, Ben A Van Der Pluijm, Laurence N WarrAbstract:[1] Mineralogical and geochemical changes in mudrock cuttings from two segments of the San Andreas Fault Observatory at Depth (SAFOD) drill hole (3066–3169 and 3292–3368 m Measured Depth) are analyzed in this study. Bulk rock samples and hand-picked fault-related grains characterized by polished surfaces and slickensides were investigated by X-ray diffraction, electron microscopy, and geochemical analysis. The elemental changes in fault-related grains along the sampled San Andreas Fault are attributed to dissolution of detrital grains (particularly feldspar and quartz) and local precipitation of illite-smectite and/or chlorite-smectite mixed layers in fractures and veins. Assuming ZrO2 and TiO2 to be immobile elements, systematic differences in element concentrations show that most of the elements are depleted in the fault-related grains compared to the wall rock lithology. Calculated mass loss between the bulk rock and picked fault rock ranges from 17 to 58% with a greater mass transport in the shallow trace of the sampled fault that marks the upper limit the fault core. The relatively large amount of element transport at temperatures of ∼110–114°C recorded throughout the core requires extensive fluid circulation during faulting. Whereas dissolution/precipitation may be partly induced by the disequilibrium between fluids and rocks during diagenetic processes, stress-induced dissolution at grain contacts is proposed as the main mechanism for extensive mineral transformation in the fault rocks and localization of neomineralization along grain interface slip surfaces.
Rikky Muller - One of the best experts on this subject based on the ideXlab platform.
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a sub mm 3 ultrasonic free floating implant for multi mote neural recording
arXiv: Signal Processing, 2019Co-Authors: Mohammad Meraj Ghanbari, David K Piech, Konlin Shen, Sina Faraji Alamouti, Cem Yalcin, Benjamin C Johnson, Jose M Carmena, Michel M Maharbiz, Rikky MullerAbstract:A 0.8 mm$^3$ wireless, ultrasonically powered, free-floating neural recording implant is presented. The device is comprised only of a 0.25 mm$^2$ recording IC and a single piezoceramic resonator that is used for both power harvesting and data transmission. Uplink data transmission is performed by analog amplitude modulation of the ultrasound echo. Using a 1.78 MHz main carrier, >35 kbps/mote equivalent uplink data rate is achieved. A technique to linearize the echo amplitude modulation is introduced, resulting in 2.5x, resulting in the highest Measured Depth/volume ratio by $\sim$3x. Orthogonal subcarrier modulation enables simultaneous operation of multiple implants, using a single-element ultrasound external transducer. Dual-mote simultaneous power up and data transmission is demonstrated at a rate of 7 kS/s at the Depth of 50 mm.
Kyuengwhan Min - One of the best experts on this subject based on the ideXlab platform.
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invasion Depth Measured in millimeters is a predictor of survival in patients with distal bile duct cancer decision tree approach
World Journal of Surgery, 2017Co-Authors: Kyuengwhan Min, Dong Hoon Kim, Byoung Kwan Son, Eun Kyung Kim, Sang Bong Ahn, Seong Hwan Kim, Young Sook Park, Jinwon Seo, Ho Young Kim, Mi Jung KwonAbstract:Background AJCC staging system is unreliable for predicting survival in distal bile duct (DBD) cancer patients, due to inter-observer variation. Measured Depth of invasion (DOI) is suggested to be more accurate to predict patients’ clinical outcome in extra-hepatic cholangiocarcinomas, but its significance in DBD cancer and cutoff values are still debatable. This study aimed to identify the optimal cutoff value of DOI in relation to prognosis in DBD cancer patients.
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invasion Depth Measured in millimeters is a predictor of survival in patients with distal bile duct cancer decision tree approach
World Journal of Surgery, 2017Co-Authors: Kyuengwhan Min, Dong Hoon Kim, Byoung Kwan Son, Eun Kyung Kim, Sang Bong Ahn, Seong Hwan Kim, Young Sook Park, Jinwon Seo, Ho Young Kim, Mi Jung KwonAbstract:AJCC staging system is unreliable for predicting survival in distal bile duct (DBD) cancer patients, due to inter-observer variation. Measured Depth of invasion (DOI) is suggested to be more accurate to predict patients’ clinical outcome in extra-hepatic cholangiocarcinomas, but its significance in DBD cancer and cutoff values are still debatable. This study aimed to identify the optimal cutoff value of DOI in relation to prognosis in DBD cancer patients. Data of 179 patients with DBD adenocarcinoma treated in three institutions were investigated. Under microscopic review, DOI was Measured. The relationships between the clinicopathological parameters and the groups based on DOI (≤3; 3–10; >10 mm) were evaluated, and the survival times of each group based on DOI and T classification were compared. Deeply invading tumors exhibited a greater tendency toward the infiltrative type, high histological grade, AJCC stage, and pancreatic, duodenal, lymphovascular and perineural invasion. The Measured DOI was significantly correlated with worse relapse-free and overall survival (all p < 0.05). In multivariate analyses, the DOI remained as one of the prognostic factors (all p < 0.05), while T classification was not a significant prognostic factor. The new prognostic models (low, intermediate, and high risk) that applied DOI and nodal metastasis showed significant difference in recurrence and survival rate (all p < 0.05). On the basis of the proposed cutoff value, the DOI could be clear and meaningful, overcoming the vagueness of the T classification for predicting clinical outcomes in patients with DBD carcinoma.
