The Experts below are selected from a list of 6558 Experts worldwide ranked by ideXlab platform

Bince Mani - One of the best experts on this subject based on the ideXlab platform.

  • evaluation of antibacterial potential of silver nanoparticles snps produced using rhizome extract of hedychium coronarium j koenig
    International Journal of Pharmacy and Pharmaceutical Sciences, 2014
    Co-Authors: Sinjumol Thomas, John S Britto, Silvy Mathew, Bince Mani
    Abstract:

    Objective: The bio-reduction of silver ions in solution into silver nanoparticles by rhizome extract of Hedychium coronarium as capping, reducing and stabilizing agent. Further, to evaluate the antibacterial activity of the phytosynthesized silver nanoparticles. Methods: Aqueous extract of dried rhizome powder of Hedychium coronarium were used for the green synthesis of silver nanoparticles. The synthesized nanoparticle was characterized by UV-vis spectroscopy, Scanning Electron Microscopy (SEM), X-ray diffraction (XRD) and Fourier Transform Infrared spectroscopy (FTIR) studies. Antibacterial activity of silver nanoparticles was carried out by disc diffusion method. Results: The observation of the peak at 428 nm in the UV-vis spectrum for phytosynthesized silver nanoparticles reveals the reduction of silver metal ions into silver nanoparticles. The FTIR analysis was performed to identify the possible functional groups involved in the synthesis of silver nanoparticles. The SEM image shows that most of the phytosynthesized silver nanoparticles have spherical morphology. The average diameter of the particles was calculated from the XRD pattern and it was found to be 24 nm. Further, it was observed that silver nanoparticles have high antibacterial activity especially against gram negative organisms. Conclusion: The rhizome extract of Hedychium coronarium could be a good candidate for the green synthesis of silver nanoparticles. The antibacterial property of silver nanoparticles is a beneficial application in the field of Medical Nanotechnology.

Sandip Kumar Khurana - One of the best experts on this subject based on the ideXlab platform.

  • nanotherapeutics an insight into healthcare and multi dimensional applications in Medical sector of the modern world
    Biomedicine & Pharmacotherapy, 2018
    Co-Authors: Minakshi Prasad, Upendra P Lambe, Basanti Brar, Ikbal Shah, J Manimegalai, Koushlesh Ranjan, Rekha Rao, Sunil Kumar, Sheefali Mahant, Sandip Kumar Khurana
    Abstract:

    Abstract In recent years Nanotechnology has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. In this context, Medical Nanotechnology involves design, fabrication, regulation, and application of therapeutic drugs and devices having a size in nano-range (1–100 nm). Owing to the revolutionary implications in drug delivery and gene therapy, nanotherapeutics has gained increasing research interest in the current Medical sector of the modern world. The areas which anticipate benefits from nano-based drug delivery systems are cancer, diabetes, infectious diseases, neurodegenerative diseases, blood disorders and orthopedic problems. The development of nanotherapeutics with multi-functionalities has considerable potential to fill the lacunae existing in the present therapeutic domain. Nanomedicines in the field of cancer management have enhanced permeability and retention of drugs thereby effectively targeting the affected tissues. Polymeric conjugates of asparaginase, polymeric micelles of paclitaxel have been recmended for various types of cancer treatment .The advancement of nano therapeutics and diagnostics can provide the improved effectiveness of the drug with less or no toxicity concerns. Similarly, diagnostic imaging is having potential future applications with newer imaging elements at nano level. The newly emerging field of nanorobotics can provide new directions in the field of healthcare. In this article, an attempt has been made to highlight the novel nanotherapeutic potentialities of polymeric nanoparticles, nanoemulsion, solid lipid nanoparticle, nanostructured lipid carriers, dendrimers, nanocapsules and nanosponges based approaches. The useful applications of these nano-medicines in the field of cancer, nutrition, and health have been discussed in details. Regulatory and safety concerns along with the commercial status of nanosystems have also been presented. In summary, a successful translation of emerging nanotherapeutics into commercial products may lead to an expansion of bioMedical science. Towards the end of the review, future perspectives of this important field have been introduced briefly.

  • Not Available
    Not Available, 2017
    Co-Authors: Minakshi Prasad, Upendra P Lambe, Basanti Brar, Ikbal Shah, Koushlesh Ranjan, Rekha Rao, Sunil Kumar, Sheefali Mahant, Manimegalai J, Sandip Kumar Khurana
    Abstract:

    Not AvailableIn recent years Nanotechnology has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. In this context, Medical Nanotechnology involves design, fabrication, regulation, and application of therapeutic drugs and devices having a size in nano-range (1–100 nm). Owing to the revolutionary implications in drug delivery and gene therapy, nanotherapeutics has gained increasing research interest in the current Medical sector of the modern world. The areas which anticipate benefits from nano-based drug delivery systems are cancer, diabetes, infectious diseases, neurodegenerative diseases, blood disorders and orthopedic problems. The development of nanotherapeutics with multi-functionalities has considerable potential to fill the lacunae existing in the present therapeutic domain. Nanomedicines in the field of cancer management have enhanced permeability and retention of drugs thereby effectively targeting the affected tissues. Polymeric conjugates of asparaginase, polymeric micelles of paclitaxel have been recmended for various types of cancer treatment .The advancement of nano therapeutics and diagnostics can provide the improved effectiveness of the drug with less or no toxicity concerns. Similarly, diagnostic imaging is having potential future applications with newer imaging elements at nano level. The newly emerging field of nanorobotics can provide new directions in the field of healthcare. In this article, an attempt has been made to highlight the novel nanotherapeutic potentialities of polymeric nanoparticles, nanoemulsion, solid lipid nanoparticle, nanostructured lipid carriers, dendrimers, nanocapsules and nanosponges based approaches. The useful applications of these nano-medicines in the field of cancer, nutrition, and health have been discussed in details. Regulatory and safety concerns along with the commercial status of nanosystems have also been presented. In summary, a successful translation of emerging nanotherapeutics into commercial products may lead to an expansion of bioMedical science. Towards the end of the review, future perspectives of this important field have been introduced briefly.Not Availabl

Sinjumol Thomas - One of the best experts on this subject based on the ideXlab platform.

  • evaluation of antibacterial potential of silver nanoparticles snps produced using rhizome extract of hedychium coronarium j koenig
    International Journal of Pharmacy and Pharmaceutical Sciences, 2014
    Co-Authors: Sinjumol Thomas, John S Britto, Silvy Mathew, Bince Mani
    Abstract:

    Objective: The bio-reduction of silver ions in solution into silver nanoparticles by rhizome extract of Hedychium coronarium as capping, reducing and stabilizing agent. Further, to evaluate the antibacterial activity of the phytosynthesized silver nanoparticles. Methods: Aqueous extract of dried rhizome powder of Hedychium coronarium were used for the green synthesis of silver nanoparticles. The synthesized nanoparticle was characterized by UV-vis spectroscopy, Scanning Electron Microscopy (SEM), X-ray diffraction (XRD) and Fourier Transform Infrared spectroscopy (FTIR) studies. Antibacterial activity of silver nanoparticles was carried out by disc diffusion method. Results: The observation of the peak at 428 nm in the UV-vis spectrum for phytosynthesized silver nanoparticles reveals the reduction of silver metal ions into silver nanoparticles. The FTIR analysis was performed to identify the possible functional groups involved in the synthesis of silver nanoparticles. The SEM image shows that most of the phytosynthesized silver nanoparticles have spherical morphology. The average diameter of the particles was calculated from the XRD pattern and it was found to be 24 nm. Further, it was observed that silver nanoparticles have high antibacterial activity especially against gram negative organisms. Conclusion: The rhizome extract of Hedychium coronarium could be a good candidate for the green synthesis of silver nanoparticles. The antibacterial property of silver nanoparticles is a beneficial application in the field of Medical Nanotechnology.

Minakshi Prasad - One of the best experts on this subject based on the ideXlab platform.

  • nanotherapeutics an insight into healthcare and multi dimensional applications in Medical sector of the modern world
    Biomedicine & Pharmacotherapy, 2018
    Co-Authors: Minakshi Prasad, Upendra P Lambe, Basanti Brar, Ikbal Shah, J Manimegalai, Koushlesh Ranjan, Rekha Rao, Sunil Kumar, Sheefali Mahant, Sandip Kumar Khurana
    Abstract:

    Abstract In recent years Nanotechnology has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. In this context, Medical Nanotechnology involves design, fabrication, regulation, and application of therapeutic drugs and devices having a size in nano-range (1–100 nm). Owing to the revolutionary implications in drug delivery and gene therapy, nanotherapeutics has gained increasing research interest in the current Medical sector of the modern world. The areas which anticipate benefits from nano-based drug delivery systems are cancer, diabetes, infectious diseases, neurodegenerative diseases, blood disorders and orthopedic problems. The development of nanotherapeutics with multi-functionalities has considerable potential to fill the lacunae existing in the present therapeutic domain. Nanomedicines in the field of cancer management have enhanced permeability and retention of drugs thereby effectively targeting the affected tissues. Polymeric conjugates of asparaginase, polymeric micelles of paclitaxel have been recmended for various types of cancer treatment .The advancement of nano therapeutics and diagnostics can provide the improved effectiveness of the drug with less or no toxicity concerns. Similarly, diagnostic imaging is having potential future applications with newer imaging elements at nano level. The newly emerging field of nanorobotics can provide new directions in the field of healthcare. In this article, an attempt has been made to highlight the novel nanotherapeutic potentialities of polymeric nanoparticles, nanoemulsion, solid lipid nanoparticle, nanostructured lipid carriers, dendrimers, nanocapsules and nanosponges based approaches. The useful applications of these nano-medicines in the field of cancer, nutrition, and health have been discussed in details. Regulatory and safety concerns along with the commercial status of nanosystems have also been presented. In summary, a successful translation of emerging nanotherapeutics into commercial products may lead to an expansion of bioMedical science. Towards the end of the review, future perspectives of this important field have been introduced briefly.

  • Not Available
    Not Available, 2017
    Co-Authors: Minakshi Prasad, Upendra P Lambe, Basanti Brar, Ikbal Shah, Koushlesh Ranjan, Rekha Rao, Sunil Kumar, Sheefali Mahant, Manimegalai J, Sandip Kumar Khurana
    Abstract:

    Not AvailableIn recent years Nanotechnology has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. In this context, Medical Nanotechnology involves design, fabrication, regulation, and application of therapeutic drugs and devices having a size in nano-range (1–100 nm). Owing to the revolutionary implications in drug delivery and gene therapy, nanotherapeutics has gained increasing research interest in the current Medical sector of the modern world. The areas which anticipate benefits from nano-based drug delivery systems are cancer, diabetes, infectious diseases, neurodegenerative diseases, blood disorders and orthopedic problems. The development of nanotherapeutics with multi-functionalities has considerable potential to fill the lacunae existing in the present therapeutic domain. Nanomedicines in the field of cancer management have enhanced permeability and retention of drugs thereby effectively targeting the affected tissues. Polymeric conjugates of asparaginase, polymeric micelles of paclitaxel have been recmended for various types of cancer treatment .The advancement of nano therapeutics and diagnostics can provide the improved effectiveness of the drug with less or no toxicity concerns. Similarly, diagnostic imaging is having potential future applications with newer imaging elements at nano level. The newly emerging field of nanorobotics can provide new directions in the field of healthcare. In this article, an attempt has been made to highlight the novel nanotherapeutic potentialities of polymeric nanoparticles, nanoemulsion, solid lipid nanoparticle, nanostructured lipid carriers, dendrimers, nanocapsules and nanosponges based approaches. The useful applications of these nano-medicines in the field of cancer, nutrition, and health have been discussed in details. Regulatory and safety concerns along with the commercial status of nanosystems have also been presented. In summary, a successful translation of emerging nanotherapeutics into commercial products may lead to an expansion of bioMedical science. Towards the end of the review, future perspectives of this important field have been introduced briefly.Not Availabl

Michael G Tyshenko - One of the best experts on this subject based on the ideXlab platform.

  • Medical Nanotechnology using genetic material and the need for precaution in design and risk assessments
    International Journal of Nanotechnology, 2008
    Co-Authors: Michael G Tyshenko
    Abstract:

    As a new field of research, Medical Nanotechnology promises a suite of potential applications for drug delivery, diagnostics and gene therapy. Deoxyribonucleic acid (DNA) is ideal at the nanoscale for use as a backbone when making scaffolded structures and more complex dendrimer constructions owing to its properties as a rigid, linear molecule. Much attention has focused on benefits from scaffolded nanoscale constructs but little has been mentioned about the risks associated with such material once inside the human body. The public is starting to focus on the health impacts of Nanotechnology including the toxic effects of nanoparticles to living systems. Even though degraded nano-scale genetic material is unlikely to present any significant problems when used therapeutically, the potential risks may be avoided by using bioinformatics database resources when designing these kinds of Nanotechnology-based therapeutics.