The Experts below are selected from a list of 195 Experts worldwide ranked by ideXlab platform
Pollianna Muniz Alves - One of the best experts on this subject based on the ideXlab platform.
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Clinical and histopathological study of the oral multifocal Melanoacanthoma: A case report.
Journal of Clinical and Experimental Dentistry, 2019Co-Authors: Ingrid-morgana-fernandes Gonçalves, Jozinete Vieira Pereira, Daliana Queiroga De Castro Gomes, Cassiano Francisco Weege Nonaka, Pollianna Muniz AlvesAbstract:Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. After incisional biopsy, the presence of numerous melanin-containing dendritic cells distributed throughout the epithelial thickness, which were S-100 (+), were observed microscopically. Final diagnosis was multifocal oral Melanoacanthoma. Follow-up for 28 months has shown appearing of more lesions in gingiva and upper lip. Therefore, the importance of differential diagnosis of oral melanoma with the group of oral pigmented lesions, and possible associated systemic diseases were evaluated.
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Clinical and histopathological study of the oral multifocal Melanoacanthoma: A case report.
Journal of clinical and experimental dentistry, 2019Co-Authors: Ingrid-morgana-fernandes Gonçalves, Daliana-queiroga-castro Gomes, Jozinete Vieira Pereira, Cassiano Francisco Weege Nonaka, Pollianna Muniz AlvesAbstract:Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. After incisional biopsy, the presence of numerous melanin-containing dendritic cells distributed throughout the epithelial thickness, which were S-100 (+), were observed microscopically. Final diagnosis was multifocal oral Melanoacanthoma. Follow-up for 28 months has shown appearing of more lesions in gingiva and upper lip. Therefore, the importance of differential diagnosis of oral melanoma with the group of oral pigmented lesions, and possible associated systemic diseases were evaluated. Key words:Melanocytes, pigmentation, oral mucosa, gingiva, differential diagnosis.
Ingrid-morgana-fernandes Gonçalves - One of the best experts on this subject based on the ideXlab platform.
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Clinical and histopathological study of the oral multifocal Melanoacanthoma: A case report.
Journal of Clinical and Experimental Dentistry, 2019Co-Authors: Ingrid-morgana-fernandes Gonçalves, Jozinete Vieira Pereira, Daliana Queiroga De Castro Gomes, Cassiano Francisco Weege Nonaka, Pollianna Muniz AlvesAbstract:Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. After incisional biopsy, the presence of numerous melanin-containing dendritic cells distributed throughout the epithelial thickness, which were S-100 (+), were observed microscopically. Final diagnosis was multifocal oral Melanoacanthoma. Follow-up for 28 months has shown appearing of more lesions in gingiva and upper lip. Therefore, the importance of differential diagnosis of oral melanoma with the group of oral pigmented lesions, and possible associated systemic diseases were evaluated.
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Clinical and histopathological study of the oral multifocal Melanoacanthoma: A case report.
Journal of clinical and experimental dentistry, 2019Co-Authors: Ingrid-morgana-fernandes Gonçalves, Daliana-queiroga-castro Gomes, Jozinete Vieira Pereira, Cassiano Francisco Weege Nonaka, Pollianna Muniz AlvesAbstract:Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. After incisional biopsy, the presence of numerous melanin-containing dendritic cells distributed throughout the epithelial thickness, which were S-100 (+), were observed microscopically. Final diagnosis was multifocal oral Melanoacanthoma. Follow-up for 28 months has shown appearing of more lesions in gingiva and upper lip. Therefore, the importance of differential diagnosis of oral melanoma with the group of oral pigmented lesions, and possible associated systemic diseases were evaluated. Key words:Melanocytes, pigmentation, oral mucosa, gingiva, differential diagnosis.
Mark A Scheper - One of the best experts on this subject based on the ideXlab platform.
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oral Melanoacanthoma in an adolescent
Pediatric Dermatology, 2010Co-Authors: John K Brooks, Arnold J Sindler, Mark A ScheperAbstract:The etiopathogenesis of oral pigmentation is diverse. One such process is the oral Melanoacanthoma, a reactive, melanocytic lesion, infrequently found in the pediatric subpopulation. To extend the knowledge of this lesion, we provide a case of gingival Melanoacanthoma in a 17-year-old male patient. In addition, a comprehensive differential diagnosis for gingival hyperpigmentations in young patients is detailed.
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multifocal Melanoacanthoma of the gingiva and hard palate
Journal of Periodontology, 2009Co-Authors: John K Brooks, Arnold J Sindler, John C Papadimitriou, Laurie A P Francis, Mark A ScheperAbstract:Background: Gingival Melanoacanthoma is an uncommon reactive lesion, typically appearing as a solitary pigmented macule. This article reports a previously undescribed case of multifocal Melanoacanthoma affecting the maxillary and mandibular gingiva and the hard palate. A literature review of Melanoacanthoma of the gingiva is also provided.Methods: An otherwise healthy 60-year-old white female sought care for a periodic dental prophylaxis. The intraoral examination was remarkable for numerous painless, brown macular lesions in all four gingival quadrants and on the hard palate (eight on the gingiva and six on the palate). The lesions ranged in size from 2 to 4 mm. The patient had only been aware of one of these lesions, estimating its existence to be <1-year duration. The unusual and widespread presentation of these lesions warranted biopsy.Results: On microscopy, all surgical specimens revealed an acanthotic population of epithelium, with dendritic melanocytes distributed throughout, and numerous melanoph...
Janete Dias Almeida - One of the best experts on this subject based on the ideXlab platform.
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Immunohistochemical features of multifocal Melanoacanthoma in the hard palate: a case report
BMC Research Notes, 2013Co-Authors: Luis Felipe Das Chagas E Silva De Carvalho, Vitor Hugo Farina, Luiz Antonio Guimarães Cabral, Adriana Aigotti Haberbeck Brandão, Ricardo Della Coletta, Janete Dias AlmeidaAbstract:Background Melanoacanthoma (MA) has been described in the oral mucosa as a solitary lesion or, occasionally, as multiple lesions. MA mainly affects dark skinned patients and grows rapidly, showing a plane or slightly raised appearance and a brown to black color. The differential diagnosis includes oral nevi, amalgam tattoos, and melanomas. We report here the case of a 58-year-old black woman who presented multiple pigmented lesions on the hard palate. Case presentation Based on the differential diagnosis of melanoma, a punch biopsy (4 mm in diameter) was performed. The material was fixed in 10% formalin, embedded in paraffin, and stained with hematoxylin-eosin or submitted to immunohistochemical analysis. Immunohistochemistry using antibodies against protein S-100, melan-A, HMB-45, MCM-2, MCM-5, Ki-67 and geminin was performed. Immunohistochemical analysis revealed strong cytoplasmic immunoreactivity of dendritic melanocytes for proteinS-100, HMB-45 and melan-A.Positive staining for proliferative markers (MCM-2, MCM-5, Ki-67) was only observed in basal and suprabasal epithelial cells, confirming the reactive etiology of the lesion. The diagnosis was oral Melanoacanthoma (MA). Conclusion The patient has been followed up for 30 months and shows no clinical alterations. MA should be included in the differential diagnosis of pigmented lesions of the oral cavity.
Cassiano Francisco Weege Nonaka - One of the best experts on this subject based on the ideXlab platform.
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Clinical and histopathological study of the oral multifocal Melanoacanthoma: A case report.
Journal of Clinical and Experimental Dentistry, 2019Co-Authors: Ingrid-morgana-fernandes Gonçalves, Jozinete Vieira Pereira, Daliana Queiroga De Castro Gomes, Cassiano Francisco Weege Nonaka, Pollianna Muniz AlvesAbstract:Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. After incisional biopsy, the presence of numerous melanin-containing dendritic cells distributed throughout the epithelial thickness, which were S-100 (+), were observed microscopically. Final diagnosis was multifocal oral Melanoacanthoma. Follow-up for 28 months has shown appearing of more lesions in gingiva and upper lip. Therefore, the importance of differential diagnosis of oral melanoma with the group of oral pigmented lesions, and possible associated systemic diseases were evaluated.
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Clinical and histopathological study of the oral multifocal Melanoacanthoma: A case report.
Journal of clinical and experimental dentistry, 2019Co-Authors: Ingrid-morgana-fernandes Gonçalves, Daliana-queiroga-castro Gomes, Jozinete Vieira Pereira, Cassiano Francisco Weege Nonaka, Pollianna Muniz AlvesAbstract:Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. After incisional biopsy, the presence of numerous melanin-containing dendritic cells distributed throughout the epithelial thickness, which were S-100 (+), were observed microscopically. Final diagnosis was multifocal oral Melanoacanthoma. Follow-up for 28 months has shown appearing of more lesions in gingiva and upper lip. Therefore, the importance of differential diagnosis of oral melanoma with the group of oral pigmented lesions, and possible associated systemic diseases were evaluated. Key words:Melanocytes, pigmentation, oral mucosa, gingiva, differential diagnosis.