The Experts below are selected from a list of 312 Experts worldwide ranked by ideXlab platform

Jianhua Wang - One of the best experts on this subject based on the ideXlab platform.

  • Clinical significance of tear Menisci in dry eye
    Eye and Contact Lens, 2012
    Co-Authors: Jianhua Li, Huixiang Ma, Aizhu Tao, Suzhong Xu, Meixiao Shen, Jianhua Wang, Fan Lu
    Abstract:

    PURPOSE: To determine the relationships among tear Menisci variables and clinical tests used in the diagnosis of dry eye patients.\n\nMETHODS: Dry eye patients (n=50; age, 35.2 years) and healthy subjects (n=48; age, 33.3 years) were recruited. Upper and lower tear Menisci were imaged noninvasively by optical coherence tomography (OCT) immediately after normal and delayed blinking in both eyes. Tear meniscus heights, areas, and radius of curvatures were obtained by custom software. Tear film break-up time was measured by fluorescein (fluorescein film tear break-up time, FTBUT) and tearscope (noninvasive tear film break-up time), ocular surface vital staining was evaluated with fluorescein (FS), and secretion was measured by Schirmer I test without and with anesthesia.\n\nRESULTS: In dry eye patients, all lower tear meniscus variables during normal blinking were correlated with all clinical tests except Schirmer I test without anesthesia. Upper tear meniscus variables were correlated with FTBUT and Schirmer I test with anesthesia. During delayed blinking, upper and lower tear Menisci variables were correlated with Schirmer I test without anesthesia and FS; however, there were no correlations between Menisci variables and FTBUT or Schirmer I test with anesthesia. In healthy subjects, only lower meniscus variables were correlated with Schirmer I test with anesthesia during normal blinking. During delayed blinking, the lower meniscus variables were correlated with only the Schirmer I test without anesthesia.\n\nCONCLUSIONS: Lower tear Menisci were correlated more strongly with the clinical tests than were upper Menisci. The tear Menisci were associated with the basic tear secretion during normal blinking. Delayed blinking may affect reflex tearing levels.

  • Diurnal Variation of Upper and Lower Tear Menisci
    American journal of ophthalmology, 2008
    Co-Authors: Meixiao Shen, Aizhu Tao, Jianhua Wang, Qi Chen, Shichu Lin
    Abstract:

    Purpose To determine diurnal variation of tear Menisci around upper and lower eyelids in normal subjects. Design Prospective laboratory investigation. Methods Twenty young healthy Chinese subjects (10 women and 10 men; mean age, 21.3 years; range, 20 to 26 years) with no history of contact lens wear or previously diagnosed dry eye were recruited. A custom-built, real-time anterior segment optical coherence tomography (OCT) instrument was used simultaneously to image the upper and lower tear Menisci. Repeated measurements immediately after blinking were conducted on both eyes during a 24-hour period, including immediately before and after sleeping. Dimensional information of the tear Menisci were obtained from the OCT images using custom software. Results There were no significant differences between right and left Menisci, nor were there any differences between females and males in the lower tear meniscus ( P > .05, repeated-measurement analysis of variance [ANOVA]). Although the lower tear meniscus variables were correlated strongly with upper meniscus variables, the lower meniscus was significantly greater than the upper one. Significant diurnal variations ( P P P Conclusions Real-time OCT can provide useful information regarding the dynamics of the tear system. Diurnal variation of the upper and lower tear Menisci occur.

  • relationships between central tear film thickness and tear Menisci of the upper and lower eyelids
    Investigative Ophthalmology & Visual Science, 2006
    Co-Authors: Jianhua Wang, James V Aquavella, Jayachandra R Palakuru, Suk Chung, Changyong Feng
    Abstract:

    PURPOSE. To investigate the relationship between central tear film thickness (TFT) and tear Menisci of the upper and lower eyelids using real-time optical coherence tomography (OCT). METHODS. Both eyes of healthy subjects were imaged with a real-time OCT to obtain height, curvature, and area of upper and lower tear Menisci simultaneously. Central TFT was indirectly measured by calculating the difference between baseline measurements of the central corneal thickness plus tear film and the true corneal thickness obtained after instillation of artificial tears. Results from two normal blinks were obtained from one eye at each visit and repeated the next day. RESULTS. The average central TFT was 3.4 2.6 m. The upper tear meniscus curvature, height, and area were 239 112 m, 268 68 m, and 22,732 11,974 m 2 respectively. There were no significant differences in curvatures, heights, or areas between upper and lower tear Menisci, nor were there any differences in measured variables between the two blinks at each visit or between the two repeated visits in the right and left eye groups (P 0.05). The upper and lower tear Menisci in each eye group on each day correlated strongly with curvature, height, and area (all P 0.03). However, no tear meniscus variable was a significant predictor of TFT (all P 0.44). CONCLUSIONS. OCT is a promising tool in the measurements of TFT and dimensional variables of tear Menisci. Upper and lower tear Menisci have nearly identical dimensions. (Invest Ophthalmol Vis Sci. 2006;47:4349‐4355) DOI:10.1167/

Meixiao Shen - One of the best experts on this subject based on the ideXlab platform.

  • Clinical significance of tear Menisci in dry eye
    Eye and Contact Lens, 2012
    Co-Authors: Jianhua Li, Huixiang Ma, Aizhu Tao, Suzhong Xu, Meixiao Shen, Jianhua Wang, Fan Lu
    Abstract:

    PURPOSE: To determine the relationships among tear Menisci variables and clinical tests used in the diagnosis of dry eye patients.\n\nMETHODS: Dry eye patients (n=50; age, 35.2 years) and healthy subjects (n=48; age, 33.3 years) were recruited. Upper and lower tear Menisci were imaged noninvasively by optical coherence tomography (OCT) immediately after normal and delayed blinking in both eyes. Tear meniscus heights, areas, and radius of curvatures were obtained by custom software. Tear film break-up time was measured by fluorescein (fluorescein film tear break-up time, FTBUT) and tearscope (noninvasive tear film break-up time), ocular surface vital staining was evaluated with fluorescein (FS), and secretion was measured by Schirmer I test without and with anesthesia.\n\nRESULTS: In dry eye patients, all lower tear meniscus variables during normal blinking were correlated with all clinical tests except Schirmer I test without anesthesia. Upper tear meniscus variables were correlated with FTBUT and Schirmer I test with anesthesia. During delayed blinking, upper and lower tear Menisci variables were correlated with Schirmer I test without anesthesia and FS; however, there were no correlations between Menisci variables and FTBUT or Schirmer I test with anesthesia. In healthy subjects, only lower meniscus variables were correlated with Schirmer I test with anesthesia during normal blinking. During delayed blinking, the lower meniscus variables were correlated with only the Schirmer I test without anesthesia.\n\nCONCLUSIONS: Lower tear Menisci were correlated more strongly with the clinical tests than were upper Menisci. The tear Menisci were associated with the basic tear secretion during normal blinking. Delayed blinking may affect reflex tearing levels.

  • Diurnal Variation of Upper and Lower Tear Menisci
    American journal of ophthalmology, 2008
    Co-Authors: Meixiao Shen, Aizhu Tao, Jianhua Wang, Qi Chen, Shichu Lin
    Abstract:

    Purpose To determine diurnal variation of tear Menisci around upper and lower eyelids in normal subjects. Design Prospective laboratory investigation. Methods Twenty young healthy Chinese subjects (10 women and 10 men; mean age, 21.3 years; range, 20 to 26 years) with no history of contact lens wear or previously diagnosed dry eye were recruited. A custom-built, real-time anterior segment optical coherence tomography (OCT) instrument was used simultaneously to image the upper and lower tear Menisci. Repeated measurements immediately after blinking were conducted on both eyes during a 24-hour period, including immediately before and after sleeping. Dimensional information of the tear Menisci were obtained from the OCT images using custom software. Results There were no significant differences between right and left Menisci, nor were there any differences between females and males in the lower tear meniscus ( P > .05, repeated-measurement analysis of variance [ANOVA]). Although the lower tear meniscus variables were correlated strongly with upper meniscus variables, the lower meniscus was significantly greater than the upper one. Significant diurnal variations ( P P P Conclusions Real-time OCT can provide useful information regarding the dynamics of the tear system. Diurnal variation of the upper and lower tear Menisci occur.

Shichu Lin - One of the best experts on this subject based on the ideXlab platform.

  • Diurnal Variation of Upper and Lower Tear Menisci
    American journal of ophthalmology, 2008
    Co-Authors: Meixiao Shen, Aizhu Tao, Jianhua Wang, Qi Chen, Shichu Lin
    Abstract:

    Purpose To determine diurnal variation of tear Menisci around upper and lower eyelids in normal subjects. Design Prospective laboratory investigation. Methods Twenty young healthy Chinese subjects (10 women and 10 men; mean age, 21.3 years; range, 20 to 26 years) with no history of contact lens wear or previously diagnosed dry eye were recruited. A custom-built, real-time anterior segment optical coherence tomography (OCT) instrument was used simultaneously to image the upper and lower tear Menisci. Repeated measurements immediately after blinking were conducted on both eyes during a 24-hour period, including immediately before and after sleeping. Dimensional information of the tear Menisci were obtained from the OCT images using custom software. Results There were no significant differences between right and left Menisci, nor were there any differences between females and males in the lower tear meniscus ( P > .05, repeated-measurement analysis of variance [ANOVA]). Although the lower tear meniscus variables were correlated strongly with upper meniscus variables, the lower meniscus was significantly greater than the upper one. Significant diurnal variations ( P P P Conclusions Real-time OCT can provide useful information regarding the dynamics of the tear system. Diurnal variation of the upper and lower tear Menisci occur.

Changyong Feng - One of the best experts on this subject based on the ideXlab platform.

  • relationships between central tear film thickness and tear Menisci of the upper and lower eyelids
    Investigative Ophthalmology & Visual Science, 2006
    Co-Authors: Jianhua Wang, James V Aquavella, Jayachandra R Palakuru, Suk Chung, Changyong Feng
    Abstract:

    PURPOSE. To investigate the relationship between central tear film thickness (TFT) and tear Menisci of the upper and lower eyelids using real-time optical coherence tomography (OCT). METHODS. Both eyes of healthy subjects were imaged with a real-time OCT to obtain height, curvature, and area of upper and lower tear Menisci simultaneously. Central TFT was indirectly measured by calculating the difference between baseline measurements of the central corneal thickness plus tear film and the true corneal thickness obtained after instillation of artificial tears. Results from two normal blinks were obtained from one eye at each visit and repeated the next day. RESULTS. The average central TFT was 3.4 2.6 m. The upper tear meniscus curvature, height, and area were 239 112 m, 268 68 m, and 22,732 11,974 m 2 respectively. There were no significant differences in curvatures, heights, or areas between upper and lower tear Menisci, nor were there any differences in measured variables between the two blinks at each visit or between the two repeated visits in the right and left eye groups (P 0.05). The upper and lower tear Menisci in each eye group on each day correlated strongly with curvature, height, and area (all P 0.03). However, no tear meniscus variable was a significant predictor of TFT (all P 0.44). CONCLUSIONS. OCT is a promising tool in the measurements of TFT and dimensional variables of tear Menisci. Upper and lower tear Menisci have nearly identical dimensions. (Invest Ophthalmol Vis Sci. 2006;47:4349‐4355) DOI:10.1167/

Aizhu Tao - One of the best experts on this subject based on the ideXlab platform.

  • Clinical significance of tear Menisci in dry eye
    Eye and Contact Lens, 2012
    Co-Authors: Jianhua Li, Huixiang Ma, Aizhu Tao, Suzhong Xu, Meixiao Shen, Jianhua Wang, Fan Lu
    Abstract:

    PURPOSE: To determine the relationships among tear Menisci variables and clinical tests used in the diagnosis of dry eye patients.\n\nMETHODS: Dry eye patients (n=50; age, 35.2 years) and healthy subjects (n=48; age, 33.3 years) were recruited. Upper and lower tear Menisci were imaged noninvasively by optical coherence tomography (OCT) immediately after normal and delayed blinking in both eyes. Tear meniscus heights, areas, and radius of curvatures were obtained by custom software. Tear film break-up time was measured by fluorescein (fluorescein film tear break-up time, FTBUT) and tearscope (noninvasive tear film break-up time), ocular surface vital staining was evaluated with fluorescein (FS), and secretion was measured by Schirmer I test without and with anesthesia.\n\nRESULTS: In dry eye patients, all lower tear meniscus variables during normal blinking were correlated with all clinical tests except Schirmer I test without anesthesia. Upper tear meniscus variables were correlated with FTBUT and Schirmer I test with anesthesia. During delayed blinking, upper and lower tear Menisci variables were correlated with Schirmer I test without anesthesia and FS; however, there were no correlations between Menisci variables and FTBUT or Schirmer I test with anesthesia. In healthy subjects, only lower meniscus variables were correlated with Schirmer I test with anesthesia during normal blinking. During delayed blinking, the lower meniscus variables were correlated with only the Schirmer I test without anesthesia.\n\nCONCLUSIONS: Lower tear Menisci were correlated more strongly with the clinical tests than were upper Menisci. The tear Menisci were associated with the basic tear secretion during normal blinking. Delayed blinking may affect reflex tearing levels.

  • Diurnal Variation of Upper and Lower Tear Menisci
    American journal of ophthalmology, 2008
    Co-Authors: Meixiao Shen, Aizhu Tao, Jianhua Wang, Qi Chen, Shichu Lin
    Abstract:

    Purpose To determine diurnal variation of tear Menisci around upper and lower eyelids in normal subjects. Design Prospective laboratory investigation. Methods Twenty young healthy Chinese subjects (10 women and 10 men; mean age, 21.3 years; range, 20 to 26 years) with no history of contact lens wear or previously diagnosed dry eye were recruited. A custom-built, real-time anterior segment optical coherence tomography (OCT) instrument was used simultaneously to image the upper and lower tear Menisci. Repeated measurements immediately after blinking were conducted on both eyes during a 24-hour period, including immediately before and after sleeping. Dimensional information of the tear Menisci were obtained from the OCT images using custom software. Results There were no significant differences between right and left Menisci, nor were there any differences between females and males in the lower tear meniscus ( P > .05, repeated-measurement analysis of variance [ANOVA]). Although the lower tear meniscus variables were correlated strongly with upper meniscus variables, the lower meniscus was significantly greater than the upper one. Significant diurnal variations ( P P P Conclusions Real-time OCT can provide useful information regarding the dynamics of the tear system. Diurnal variation of the upper and lower tear Menisci occur.