The Experts below are selected from a list of 3294 Experts worldwide ranked by ideXlab platform

Takayoshi Nakano - One of the best experts on this subject based on the ideXlab platform.

  • design and development of ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Materials & Design, 2021
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Pan Wang, Takayoshi Nakano
    Abstract:

    Abstract Applying empirical alloy parameters (including Mo equivalent), the predicted ground state diagram, and thermodynamic calculations, noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys for Metallic Biomaterials (BioHEAs) were designed and newly developed. It is found that the Moeq and valence electron concentration (VEC) parameters are useful for alloy design involving BCC structure formation in bio medium-entropy alloys and BioHEAs. Finally, we find a Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at.%) BioHEA that exhibits biocompatibility comparable to that of CP–Ti, higher mechanical strength than CP–Ti, and an appreciable room-temperature tensile ductility. The current findings pave the way for new Ti–Zr–Hf–Nb–Ta–Mo BioHEAs development and are applicable for another BioHEA alloys system.

  • novel ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Social Science Research Network, 2020
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys (HEAs) for Metallic Biomaterials (BioHEAs) were designed and developed. Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at%) BioHEA exhibits biocompatibility that is comparable to that of commercial-purity Ti (CP–Ti), with higher mechanical strength than CP–Ti and appropriate room-temperature ductility available for tensile tests. The Moeq, as well as the VEC parameters, were useful for alloy design with body-centered cubic (BCC) structure formation in bio medium-entropy alloys and BioHEAs.

  • design and fabrication of ti zr hf cr mo and ti zr hf co cr mo high entropy alloys as Metallic Biomaterials
    Materials Science and Engineering: C, 2020
    Co-Authors: Takeshi Nagase, Yuuka Iijima, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Novel TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo high-entropy alloys for Metallic Biomaterials (bio-HEAs) were developed based on the combination of Ti-Nb-Ta-Zr-Mo alloy system and Co-Cr-Mo alloy system as commercially-used Metallic Biomaterials. Ti-Zr-Hf-Cr-Mo and Ti-Zr-Hf-Co-Cr-Mo bio-HEAs were designed using (a) a tree-like diagram for alloy development, (b) empirical alloy parameters for solid-solution-phase formation, and (c) thermodynamic calculations focused on solidification. The newly-developed bio-HEAs overcomes the limitation of classical Metallic Biomaterials by the improvement of (i) mechanical hardness and (ii) biocompatibility all together. The TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs showed superior biocompatibility comparable to that of commercial-purity Ti. The superior biocompatibility, high mechanical hardness and low liquidus temperature for the material processing in TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs compared with the Ti-Nb-Ta-Zr-Mo bio-HEAs gave the authenticity of the application of bio-HEAs for orthopedic implants with multiple functions.

  • development of non equiatomic ti nb ta zr mo high entropy alloys for Metallic Biomaterials
    Scripta Materialia, 2019
    Co-Authors: Takao Hori, Takeshi Nagase, Aira Matsugaki, Mitsuharu Todai, Takayoshi Nakano
    Abstract:

    Abstract Nobel non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys (HEAs) for Metallic Biomaterials (bio-HEAs) were designed and developed. The pseudo-binary phase diagrams focusing on solidification were constructed by thermodynamic calculations. The shifting the alloy composition of the equiatomic TiNbTaZrMo bio-HEA can realize the drastic improvement of the deformability. Notably, the non-equiatomic Ti, Zr-rich composition stimulated the molecular interaction between biological cells and bio-HEA, indicating the possibility of the proposed non-equiatomic Ti-Nb-Ta-Zr-Mo HEAs as an advanced biomaterial for bone tissue engineering applications. This is the first achievement for the alloy design including the control of alloy composition for the development of new bio-HEAs.

  • physical and mechanical properties of Metallic Biomaterials
    2019
    Co-Authors: Takayoshi Nakano
    Abstract:

    Abstract Almost all Metallic Biomaterials are crystalline with a regular and periodic atomic arrangement, and their mechanical properties are dominantly controlled by dislocation motion and twinning closely related to the crystal structure. Metals for biomedical applications are substantially understood in Metallic materials science, and the mechanical properties can be improved by controlling the lattice defects or phase transformations at the atomic level. In this chapter, selected Metallic materials applied in the biomedical field such as stainless steel, cobalt-chromium (Co Cr) alloys, pure titanium (Ti), titanium alloys and alloys of noble metals, including products by metal additive manufacturing from that are simultaneously controlled by controlling their shape, and microstructural parameters are considered. The basic principles that govern the mechanical properties of Metallic materials used in biomedical applications are described from the viewpoint of their crystal structure, slip deformation, dislocation, phase diagram, and recrystallization. The relationship between the microstructure and mechanical properties, and the methodologies for strengthening these metals are briefly mentioned. In addition, the requirements with which Metallic Biomaterials for implantation would need to comply are discussed with respect to the bone microstructure. Strategies for improving the in vivo mechanical properties by combining Metallic Biomaterials and bones are also considered. These strategies are designed to suppress stress shielding by using materials with low Young's modulus comparable to that in bone.

Takeshi Nagase - One of the best experts on this subject based on the ideXlab platform.

  • design and development of ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Materials & Design, 2021
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Pan Wang, Takayoshi Nakano
    Abstract:

    Abstract Applying empirical alloy parameters (including Mo equivalent), the predicted ground state diagram, and thermodynamic calculations, noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys for Metallic Biomaterials (BioHEAs) were designed and newly developed. It is found that the Moeq and valence electron concentration (VEC) parameters are useful for alloy design involving BCC structure formation in bio medium-entropy alloys and BioHEAs. Finally, we find a Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at.%) BioHEA that exhibits biocompatibility comparable to that of CP–Ti, higher mechanical strength than CP–Ti, and an appreciable room-temperature tensile ductility. The current findings pave the way for new Ti–Zr–Hf–Nb–Ta–Mo BioHEAs development and are applicable for another BioHEA alloys system.

  • novel ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Social Science Research Network, 2020
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys (HEAs) for Metallic Biomaterials (BioHEAs) were designed and developed. Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at%) BioHEA exhibits biocompatibility that is comparable to that of commercial-purity Ti (CP–Ti), with higher mechanical strength than CP–Ti and appropriate room-temperature ductility available for tensile tests. The Moeq, as well as the VEC parameters, were useful for alloy design with body-centered cubic (BCC) structure formation in bio medium-entropy alloys and BioHEAs.

  • design and fabrication of ti zr hf cr mo and ti zr hf co cr mo high entropy alloys as Metallic Biomaterials
    Materials Science and Engineering: C, 2020
    Co-Authors: Takeshi Nagase, Yuuka Iijima, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Novel TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo high-entropy alloys for Metallic Biomaterials (bio-HEAs) were developed based on the combination of Ti-Nb-Ta-Zr-Mo alloy system and Co-Cr-Mo alloy system as commercially-used Metallic Biomaterials. Ti-Zr-Hf-Cr-Mo and Ti-Zr-Hf-Co-Cr-Mo bio-HEAs were designed using (a) a tree-like diagram for alloy development, (b) empirical alloy parameters for solid-solution-phase formation, and (c) thermodynamic calculations focused on solidification. The newly-developed bio-HEAs overcomes the limitation of classical Metallic Biomaterials by the improvement of (i) mechanical hardness and (ii) biocompatibility all together. The TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs showed superior biocompatibility comparable to that of commercial-purity Ti. The superior biocompatibility, high mechanical hardness and low liquidus temperature for the material processing in TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs compared with the Ti-Nb-Ta-Zr-Mo bio-HEAs gave the authenticity of the application of bio-HEAs for orthopedic implants with multiple functions.

  • development of non equiatomic ti nb ta zr mo high entropy alloys for Metallic Biomaterials
    Scripta Materialia, 2019
    Co-Authors: Takao Hori, Takeshi Nagase, Aira Matsugaki, Mitsuharu Todai, Takayoshi Nakano
    Abstract:

    Abstract Nobel non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys (HEAs) for Metallic Biomaterials (bio-HEAs) were designed and developed. The pseudo-binary phase diagrams focusing on solidification were constructed by thermodynamic calculations. The shifting the alloy composition of the equiatomic TiNbTaZrMo bio-HEA can realize the drastic improvement of the deformability. Notably, the non-equiatomic Ti, Zr-rich composition stimulated the molecular interaction between biological cells and bio-HEA, indicating the possibility of the proposed non-equiatomic Ti-Nb-Ta-Zr-Mo HEAs as an advanced biomaterial for bone tissue engineering applications. This is the first achievement for the alloy design including the control of alloy composition for the development of new bio-HEAs.

  • microstructure of equiatomic and non equiatomic ti nb ta zr mo high entropy alloys for Metallic Biomaterials
    Journal of Alloys and Compounds, 2018
    Co-Authors: Takeshi Nagase, Mitsuharu Todai, Takao Hori, Takayoshi Nakano
    Abstract:

    Abstract The microstructures of equiatomic TiNbTaZrMo (Ti20Nb20Ta20Zr20Mo20—subscript numerals denote at.%) and non-equiatomic Ti2.6NbTaZrMo (Ti39.4Nb15.2Ta15.2Zr15.2Mo15.2) high-entropy alloys (HEAs) were investigated for use in Metallic Biomaterials, and discussed based on their thermodynamics. Equiaxial dendrite structures were observed in the as-cast specimens. Ta, Nb, and Mo were abundant in the main dendrite phase with a body centered cubic (bcc) structure, while Ti and Zr showed a tendency to be abundant in the inter-dendrite region with a bcc structure. The distribution of the constituent elements can be explained through the distribution coefficients during solidification estimated using thermodynamic calculations. The thermodynamic calculations focusing on the solidification process were effective not only for the evaluation of the solidification microstructure, but also for the design of Ti-Nb-Ta-Zr-Mo-based HEAs. The non-equiatomic Ti2.6NbTaZrMo HEA (Ti39.4Nb15.2Ta15.2Zr15.2Mo15.2) was designed based on thermodynamic calculations and the solidification microstructure was studied.

Aira Matsugaki - One of the best experts on this subject based on the ideXlab platform.

  • design and development of ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Materials & Design, 2021
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Pan Wang, Takayoshi Nakano
    Abstract:

    Abstract Applying empirical alloy parameters (including Mo equivalent), the predicted ground state diagram, and thermodynamic calculations, noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys for Metallic Biomaterials (BioHEAs) were designed and newly developed. It is found that the Moeq and valence electron concentration (VEC) parameters are useful for alloy design involving BCC structure formation in bio medium-entropy alloys and BioHEAs. Finally, we find a Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at.%) BioHEA that exhibits biocompatibility comparable to that of CP–Ti, higher mechanical strength than CP–Ti, and an appreciable room-temperature tensile ductility. The current findings pave the way for new Ti–Zr–Hf–Nb–Ta–Mo BioHEAs development and are applicable for another BioHEA alloys system.

  • novel ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Social Science Research Network, 2020
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys (HEAs) for Metallic Biomaterials (BioHEAs) were designed and developed. Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at%) BioHEA exhibits biocompatibility that is comparable to that of commercial-purity Ti (CP–Ti), with higher mechanical strength than CP–Ti and appropriate room-temperature ductility available for tensile tests. The Moeq, as well as the VEC parameters, were useful for alloy design with body-centered cubic (BCC) structure formation in bio medium-entropy alloys and BioHEAs.

  • design and fabrication of ti zr hf cr mo and ti zr hf co cr mo high entropy alloys as Metallic Biomaterials
    Materials Science and Engineering: C, 2020
    Co-Authors: Takeshi Nagase, Yuuka Iijima, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Novel TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo high-entropy alloys for Metallic Biomaterials (bio-HEAs) were developed based on the combination of Ti-Nb-Ta-Zr-Mo alloy system and Co-Cr-Mo alloy system as commercially-used Metallic Biomaterials. Ti-Zr-Hf-Cr-Mo and Ti-Zr-Hf-Co-Cr-Mo bio-HEAs were designed using (a) a tree-like diagram for alloy development, (b) empirical alloy parameters for solid-solution-phase formation, and (c) thermodynamic calculations focused on solidification. The newly-developed bio-HEAs overcomes the limitation of classical Metallic Biomaterials by the improvement of (i) mechanical hardness and (ii) biocompatibility all together. The TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs showed superior biocompatibility comparable to that of commercial-purity Ti. The superior biocompatibility, high mechanical hardness and low liquidus temperature for the material processing in TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs compared with the Ti-Nb-Ta-Zr-Mo bio-HEAs gave the authenticity of the application of bio-HEAs for orthopedic implants with multiple functions.

  • development of non equiatomic ti nb ta zr mo high entropy alloys for Metallic Biomaterials
    Scripta Materialia, 2019
    Co-Authors: Takao Hori, Takeshi Nagase, Aira Matsugaki, Mitsuharu Todai, Takayoshi Nakano
    Abstract:

    Abstract Nobel non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys (HEAs) for Metallic Biomaterials (bio-HEAs) were designed and developed. The pseudo-binary phase diagrams focusing on solidification were constructed by thermodynamic calculations. The shifting the alloy composition of the equiatomic TiNbTaZrMo bio-HEA can realize the drastic improvement of the deformability. Notably, the non-equiatomic Ti, Zr-rich composition stimulated the molecular interaction between biological cells and bio-HEA, indicating the possibility of the proposed non-equiatomic Ti-Nb-Ta-Zr-Mo HEAs as an advanced biomaterial for bone tissue engineering applications. This is the first achievement for the alloy design including the control of alloy composition for the development of new bio-HEAs.

  • novel tinbtazrmo high entropy alloys for Metallic Biomaterials
    Scripta Materialia, 2017
    Co-Authors: Mitsuharu Todai, Takeshi Nagase, Aira Matsugaki, Takao Hori, Aiko Sekita, Takayoshi Nakano
    Abstract:

    Abstract A novel equiatomic TiNbTaZrMo high-entropy alloy (HEA) was developed as a new Metallic biomaterial. The constituent elements of the HEA were biocomparable, and the HEA was designed based on parameters such as the mixing enthalpy (Δ H mix ), the omega parameter ( Ω ), the delta parameter ( δ ), and the valence electron concentration (VEC) theory. The bcc solid solution phases with the different lattice constants were obtained in as-cast and annealed states. The HEA showed considerable strength with deformability and superior biocompatibility comparable to pure Ti. This study demonstrated the possibility of using HEAs as a new class of Metallic Biomaterials.

Yuuka Iijima - One of the best experts on this subject based on the ideXlab platform.

  • design and development of ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Materials & Design, 2021
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Pan Wang, Takayoshi Nakano
    Abstract:

    Abstract Applying empirical alloy parameters (including Mo equivalent), the predicted ground state diagram, and thermodynamic calculations, noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys for Metallic Biomaterials (BioHEAs) were designed and newly developed. It is found that the Moeq and valence electron concentration (VEC) parameters are useful for alloy design involving BCC structure formation in bio medium-entropy alloys and BioHEAs. Finally, we find a Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at.%) BioHEA that exhibits biocompatibility comparable to that of CP–Ti, higher mechanical strength than CP–Ti, and an appreciable room-temperature tensile ductility. The current findings pave the way for new Ti–Zr–Hf–Nb–Ta–Mo BioHEAs development and are applicable for another BioHEA alloys system.

  • novel ti zr hf nb ta mo high entropy alloys for Metallic Biomaterials
    Social Science Research Network, 2020
    Co-Authors: Yuuka Iijima, Takeshi Nagase, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Noble nonequiatomic Ti–Zr–Hf–Nb–Ta–Mo high-entropy alloys (HEAs) for Metallic Biomaterials (BioHEAs) were designed and developed. Ti28.33Zr28.33Hf28.33Nb6.74Ta6.74Mo1.55 (at%) BioHEA exhibits biocompatibility that is comparable to that of commercial-purity Ti (CP–Ti), with higher mechanical strength than CP–Ti and appropriate room-temperature ductility available for tensile tests. The Moeq, as well as the VEC parameters, were useful for alloy design with body-centered cubic (BCC) structure formation in bio medium-entropy alloys and BioHEAs.

  • design and fabrication of ti zr hf cr mo and ti zr hf co cr mo high entropy alloys as Metallic Biomaterials
    Materials Science and Engineering: C, 2020
    Co-Authors: Takeshi Nagase, Yuuka Iijima, Aira Matsugaki, Kei Ameyama, Takayoshi Nakano
    Abstract:

    Novel TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo high-entropy alloys for Metallic Biomaterials (bio-HEAs) were developed based on the combination of Ti-Nb-Ta-Zr-Mo alloy system and Co-Cr-Mo alloy system as commercially-used Metallic Biomaterials. Ti-Zr-Hf-Cr-Mo and Ti-Zr-Hf-Co-Cr-Mo bio-HEAs were designed using (a) a tree-like diagram for alloy development, (b) empirical alloy parameters for solid-solution-phase formation, and (c) thermodynamic calculations focused on solidification. The newly-developed bio-HEAs overcomes the limitation of classical Metallic Biomaterials by the improvement of (i) mechanical hardness and (ii) biocompatibility all together. The TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs showed superior biocompatibility comparable to that of commercial-purity Ti. The superior biocompatibility, high mechanical hardness and low liquidus temperature for the material processing in TiZrHfCr0.2Mo and TiZrHfCo0.07Cr0.07Mo bio-HEAs compared with the Ti-Nb-Ta-Zr-Mo bio-HEAs gave the authenticity of the application of bio-HEAs for orthopedic implants with multiple functions.

Takao Hori - One of the best experts on this subject based on the ideXlab platform.

  • development of non equiatomic ti nb ta zr mo high entropy alloys for Metallic Biomaterials
    Scripta Materialia, 2019
    Co-Authors: Takao Hori, Takeshi Nagase, Aira Matsugaki, Mitsuharu Todai, Takayoshi Nakano
    Abstract:

    Abstract Nobel non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys (HEAs) for Metallic Biomaterials (bio-HEAs) were designed and developed. The pseudo-binary phase diagrams focusing on solidification were constructed by thermodynamic calculations. The shifting the alloy composition of the equiatomic TiNbTaZrMo bio-HEA can realize the drastic improvement of the deformability. Notably, the non-equiatomic Ti, Zr-rich composition stimulated the molecular interaction between biological cells and bio-HEA, indicating the possibility of the proposed non-equiatomic Ti-Nb-Ta-Zr-Mo HEAs as an advanced biomaterial for bone tissue engineering applications. This is the first achievement for the alloy design including the control of alloy composition for the development of new bio-HEAs.

  • microstructure of equiatomic and non equiatomic ti nb ta zr mo high entropy alloys for Metallic Biomaterials
    Journal of Alloys and Compounds, 2018
    Co-Authors: Takeshi Nagase, Mitsuharu Todai, Takao Hori, Takayoshi Nakano
    Abstract:

    Abstract The microstructures of equiatomic TiNbTaZrMo (Ti20Nb20Ta20Zr20Mo20—subscript numerals denote at.%) and non-equiatomic Ti2.6NbTaZrMo (Ti39.4Nb15.2Ta15.2Zr15.2Mo15.2) high-entropy alloys (HEAs) were investigated for use in Metallic Biomaterials, and discussed based on their thermodynamics. Equiaxial dendrite structures were observed in the as-cast specimens. Ta, Nb, and Mo were abundant in the main dendrite phase with a body centered cubic (bcc) structure, while Ti and Zr showed a tendency to be abundant in the inter-dendrite region with a bcc structure. The distribution of the constituent elements can be explained through the distribution coefficients during solidification estimated using thermodynamic calculations. The thermodynamic calculations focusing on the solidification process were effective not only for the evaluation of the solidification microstructure, but also for the design of Ti-Nb-Ta-Zr-Mo-based HEAs. The non-equiatomic Ti2.6NbTaZrMo HEA (Ti39.4Nb15.2Ta15.2Zr15.2Mo15.2) was designed based on thermodynamic calculations and the solidification microstructure was studied.

  • novel tinbtazrmo high entropy alloys for Metallic Biomaterials
    Scripta Materialia, 2017
    Co-Authors: Mitsuharu Todai, Takeshi Nagase, Aira Matsugaki, Takao Hori, Aiko Sekita, Takayoshi Nakano
    Abstract:

    Abstract A novel equiatomic TiNbTaZrMo high-entropy alloy (HEA) was developed as a new Metallic biomaterial. The constituent elements of the HEA were biocomparable, and the HEA was designed based on parameters such as the mixing enthalpy (Δ H mix ), the omega parameter ( Ω ), the delta parameter ( δ ), and the valence electron concentration (VEC) theory. The bcc solid solution phases with the different lattice constants were obtained in as-cast and annealed states. The HEA showed considerable strength with deformability and superior biocompatibility comparable to pure Ti. This study demonstrated the possibility of using HEAs as a new class of Metallic Biomaterials.