The Experts below are selected from a list of 1854 Experts worldwide ranked by ideXlab platform

Michael Murphy - One of the best experts on this subject based on the ideXlab platform.

  • Spinal Metallosis: a systematic review
    European Spine Journal, 2016
    Co-Authors: Yoni Goldenberg, Jin W. Tee, Cesar M. Salinas-la Rosa, Michael Murphy
    Abstract:

    Purpose To document a rarely reported complication associated with spinal instrumentation and to evaluate the current literature on spinal Metallosis and spinal metalloma. Methods A local case report is presented. EBSCOhost, PubMed and ScienceDirect databases were used to conduct a systematic review for articles describing spinal Metallosis and spinal metalloma. Results A total of 836 articles were identified using the terms “metalloma” or “Metallosis”. Exclusion of arthroplasty-related abstracts retrieved 46 articles of which 3 full text articles presenting spinal metalloma as a causative pathological finding responsible for neurological signs and symptoms in patients with previous spinal fusion instrumentation were reviewed. Our case is the first described with titanium-composed posterior instrumentation and fifth reported, demonstrating the phenomena of neurological symptoms and signs attributed directly to neural tissue compression by spinal metalloma after spinal instrumentation. Conclusion Spinal Metallosis can present weeks to years after spinal instrumentation surgery and is a potential cause of neural compression. This process appears to be independent of the instrument composition as Metallosis has now been demonstrated in both titanium and stainless steel constructs.

  • Spinal Metallosis: a systematic review.
    European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2016
    Co-Authors: Yoni Goldenberg, Jin W. Tee, Cesar M. Salinas-la Rosa, Michael Murphy
    Abstract:

    Purpose To document a rarely reported complication associated with spinal instrumentation and to evaluate the current literature on spinal Metallosis and spinal metalloma.

Pedro Xavier - One of the best experts on this subject based on the ideXlab platform.

  • Metallosis: A New Form of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants Syndrome (ASIA)?
    European Journal of Case Reports in Internal Medicine, 2019
    Co-Authors: Pedro Xavier, Sergio Brito, Jorge Dantas, Sofía Duque, José Guimarães Consciência, Luis Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition. LEARNING POINTS Asia syndrome is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is an uncommon condition with local and systemic presentation. A high level of suspicion and close monitoring is needed in patients with vague systemic complaints. Keywords: ASIA syndrome, Metallosis BACKGROUND Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity, described in 2011, in which exposure to an adjuvant triggers an aberrant autoimmune response. Initially, ASIA was associated with different conditions such as siliconosis, Gulf war syndrome (GWS), macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena. The diagnosis is made when two major criteria or one major criterion and two minor criteria are present (Table 1). Table 1 Proposed criteria for the diagnosis of autoimmune/autoinflammatory syndrome induced by adjuvants syndrome (ASIA)

  • Metallosis a new form of autoimmune autoinflammatory syndrome induced by adjuvants syndrome asia
    European Journal of Case Reports in Internal Medicine, 2019
    Co-Authors: Rita Vaz, Sergio Brito, Jorge Dantas, Pedro Xavier, Sofía Duque, José Guimarães Consciência, Luis Antonio Monteiro Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition. LEARNING POINTS Asia syndrome is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is an uncommon condition with local and systemic presentation. A high level of suspicion and close monitoring is needed in patients with vague systemic complaints. Keywords: ASIA syndrome, Metallosis BACKGROUND Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity, described in 2011, in which exposure to an adjuvant triggers an aberrant autoimmune response. Initially, ASIA was associated with different conditions such as siliconosis, Gulf war syndrome (GWS), macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena. The diagnosis is made when two major criteria or one major criterion and two minor criteria are present (Table 1). Table 1 Proposed criteria for the diagnosis of autoimmune/autoinflammatory syndrome induced by adjuvants syndrome (ASIA)

  • Metallosis: A New Form of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants Syndrome (ASIA)?
    SMC MEDIA SRL, 2019
    Co-Authors: Rita Alexandra Vaz, Sergio Brito, Jorge Dantas, Pedro Xavier, Sofía Duque, José Guimarães Consciência, Luis Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition

Luis Campos - One of the best experts on this subject based on the ideXlab platform.

  • Metallosis: A New Form of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants Syndrome (ASIA)?
    European Journal of Case Reports in Internal Medicine, 2019
    Co-Authors: Pedro Xavier, Sergio Brito, Jorge Dantas, Sofía Duque, José Guimarães Consciência, Luis Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition. LEARNING POINTS Asia syndrome is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is an uncommon condition with local and systemic presentation. A high level of suspicion and close monitoring is needed in patients with vague systemic complaints. Keywords: ASIA syndrome, Metallosis BACKGROUND Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity, described in 2011, in which exposure to an adjuvant triggers an aberrant autoimmune response. Initially, ASIA was associated with different conditions such as siliconosis, Gulf war syndrome (GWS), macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena. The diagnosis is made when two major criteria or one major criterion and two minor criteria are present (Table 1). Table 1 Proposed criteria for the diagnosis of autoimmune/autoinflammatory syndrome induced by adjuvants syndrome (ASIA)

  • Metallosis: A New Form of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants Syndrome (ASIA)?
    SMC MEDIA SRL, 2019
    Co-Authors: Rita Alexandra Vaz, Sergio Brito, Jorge Dantas, Pedro Xavier, Sofía Duque, José Guimarães Consciência, Luis Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition

Yoni Goldenberg - One of the best experts on this subject based on the ideXlab platform.

  • Spinal Metallosis: a systematic review
    European Spine Journal, 2016
    Co-Authors: Yoni Goldenberg, Jin W. Tee, Cesar M. Salinas-la Rosa, Michael Murphy
    Abstract:

    Purpose To document a rarely reported complication associated with spinal instrumentation and to evaluate the current literature on spinal Metallosis and spinal metalloma. Methods A local case report is presented. EBSCOhost, PubMed and ScienceDirect databases were used to conduct a systematic review for articles describing spinal Metallosis and spinal metalloma. Results A total of 836 articles were identified using the terms “metalloma” or “Metallosis”. Exclusion of arthroplasty-related abstracts retrieved 46 articles of which 3 full text articles presenting spinal metalloma as a causative pathological finding responsible for neurological signs and symptoms in patients with previous spinal fusion instrumentation were reviewed. Our case is the first described with titanium-composed posterior instrumentation and fifth reported, demonstrating the phenomena of neurological symptoms and signs attributed directly to neural tissue compression by spinal metalloma after spinal instrumentation. Conclusion Spinal Metallosis can present weeks to years after spinal instrumentation surgery and is a potential cause of neural compression. This process appears to be independent of the instrument composition as Metallosis has now been demonstrated in both titanium and stainless steel constructs.

  • Spinal Metallosis: a systematic review.
    European spine journal : official publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cerv, 2016
    Co-Authors: Yoni Goldenberg, Jin W. Tee, Cesar M. Salinas-la Rosa, Michael Murphy
    Abstract:

    Purpose To document a rarely reported complication associated with spinal instrumentation and to evaluate the current literature on spinal Metallosis and spinal metalloma.

José Guimarães Consciência - One of the best experts on this subject based on the ideXlab platform.

  • Metallosis: A New Form of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants Syndrome (ASIA)?
    European Journal of Case Reports in Internal Medicine, 2019
    Co-Authors: Pedro Xavier, Sergio Brito, Jorge Dantas, Sofía Duque, José Guimarães Consciência, Luis Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition. LEARNING POINTS Asia syndrome is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is an uncommon condition with local and systemic presentation. A high level of suspicion and close monitoring is needed in patients with vague systemic complaints. Keywords: ASIA syndrome, Metallosis BACKGROUND Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity, described in 2011, in which exposure to an adjuvant triggers an aberrant autoimmune response. Initially, ASIA was associated with different conditions such as siliconosis, Gulf war syndrome (GWS), macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena. The diagnosis is made when two major criteria or one major criterion and two minor criteria are present (Table 1). Table 1 Proposed criteria for the diagnosis of autoimmune/autoinflammatory syndrome induced by adjuvants syndrome (ASIA)

  • Metallosis a new form of autoimmune autoinflammatory syndrome induced by adjuvants syndrome asia
    European Journal of Case Reports in Internal Medicine, 2019
    Co-Authors: Rita Vaz, Sergio Brito, Jorge Dantas, Pedro Xavier, Sofía Duque, José Guimarães Consciência, Luis Antonio Monteiro Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition. LEARNING POINTS Asia syndrome is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is an uncommon condition with local and systemic presentation. A high level of suspicion and close monitoring is needed in patients with vague systemic complaints. Keywords: ASIA syndrome, Metallosis BACKGROUND Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity, described in 2011, in which exposure to an adjuvant triggers an aberrant autoimmune response. Initially, ASIA was associated with different conditions such as siliconosis, Gulf war syndrome (GWS), macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena. The diagnosis is made when two major criteria or one major criterion and two minor criteria are present (Table 1). Table 1 Proposed criteria for the diagnosis of autoimmune/autoinflammatory syndrome induced by adjuvants syndrome (ASIA)

  • Metallosis: A New Form of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants Syndrome (ASIA)?
    SMC MEDIA SRL, 2019
    Co-Authors: Rita Alexandra Vaz, Sergio Brito, Jorge Dantas, Pedro Xavier, Sofía Duque, José Guimarães Consciência, Luis Campos
    Abstract:

    Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) is a new entity in which exposure to an adjuvant triggers an aberrant autoimmune response. Metallosis is a rare condition characterized by the deposition and build-up of metal debris in the soft tissues of the body associated with metal-on-metal (MOM) prosthetic devices. It can present with local/systemic symptoms and signs due to a chronic inflammatory host response. The authors present the case of a 51-year-old woman with a 6-month history of systemic complaints due to intoxication with metal ions from hip Metallosis. This case highlights the importance of follow-up and continuous monitoring of patients with a hip prosthesis. As this is a rare condition, a patient presenting with unspecific symptoms such as ASIA syndrome induced by Metallosis requires a high level of clinical suspicion as the removal of the adjuvant can resolve the condition