The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Tetsuro Oshika - One of the best experts on this subject based on the ideXlab platform.

  • relationship between Metamorphopsia and inner retinal microstructure following intravitreal ranibizumab injection for branch retinal vein occlusion
    Scientific Reports, 2021
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Fumiki Okamoto, Shohei Morikawa, Tomoya Murakami, Syed Amal Hussnain, Tetsuro Oshika
    Abstract:

    To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO), and to assess the relationship between Metamorphopsia and inner retinal microstructure and other factors. Thirty-three treatment-naive eyes of 33 patients with macular edema caused by BRVO with at least 12 months of follow-up were included. The degree of Metamorphopsia was quantified using the M-CHARTS. Retinal microstructure was assessed with spectral-domain optical coherence tomography. Disorganization of the retinal inner layers (DRIL) at the first month after resolution of the macular edema (early DRIL) and at 12 months after treatment (after DRIL) was studied. Central retinal thickness (CRT), and status of the external limiting membrane as well as ellipsoid zone were also evaluated. IVR treatment significantly improved best-corrected visual acuity (BCVA) and CRT, but the mean Metamorphopsia score did not improve even after 12 months. Post-treatment Metamorphopsia scores showed a significant correlation with pre-treatment Metamorphopsia scores (P < 0.005), the extent of early DRIL (P < 0.05) and after DRIL (P < 0.05), and the number of injections (P < 0.05). Multivariate analysis revealed that the post-treatment mean Metamorphopsia score was significantly correlated with the pre-treatment mean Metamorphopsia score (P < 0.05). IVR treatment significantly improved BCVA and CRT, but not Metamorphopsia. Post-treatment Metamorphopsia scores were significantly associated with pre-treatment Metamorphopsia scores, the extent of DRIL, and the number of injections. Prognostic factor of Metamorphopsia was the degree of pre-treatment Metamorphopsia.

  • TIME COURSE OF CHANGES IN Metamorphopsia FOLLOWING INTRAVITREAL RANIBIZUMAB INJECTION FOR BRANCH RETINAL VEIN OCCLUSION.
    Retina, 2018
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Shohei Morikawa, Tetsuro Oshika
    Abstract:

    PURPOSE To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO) and to assess the relationship between retinal microstructure and Metamorphopsia. METHODS Subjects were 39 eyes of 39 patients with branch retinal vein occlusion. The severity of Metamorphopsia was quantified using the M-CHARTS before and 1, 2, 3, 4, 5, and 6 months after treatment. Based on optical coherence tomography (OCT) images, we assessed central retinal thickness (CRT) and status of the external limiting membrane (ELM) and ellipsoid zone (EZ). The association between retinal microstructure and Metamorphopsia was analyzed in 24 eyes with treatment-naive branch retinal vein occlusion. RESULTS Intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity (BCVA) and central retinal thickness (P < 0.0001, P < 0.0001, respectively), but Metamorphopsia did not improve by treatment. Posttreatment Metamorphopsia scores showed a significant correlation with duration of symptoms (P < 0.05) and pretreatment Metamorphopsia scores (P < 0.01). Posttreatment Metamorphopsia score was significantly worse in patients with disruption of external limiting membrane (P < 0.05). CONCLUSIONS In patients with branch retinal vein occlusion, intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity and central retinal thickness, but not Metamorphopsia. The severity of posttreatment Metamorphopsia was significantly associated with duration of symptoms, degree of pretreatment Metamorphopsia, and posttreatment integrity of external limiting membrane.

  • changes in Metamorphopsia and optical coherence tomography findings after successful retinal detachment surgery
    Retina-the Journal of Retinal and Vitreous Diseases, 2017
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    Purpose:To investigate changes in Metamorphopsia after rhegmatogenous retinal detachment surgery and to evaluate the relationship between Metamorphopsia and retinal microstructures assessed with optical coherence tomography.Methods:The study included 47 eyes of 47 patients undergoing retinal detachm

  • RELATIONSHIP BETWEEN Metamorphopsia AND INTRARETINAL CYSTS WITHIN THE FLUID CUFF AFTER SURGERY FOR IDIOPATHIC MACULAR HOLE.
    Retina, 2017
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    PURPOSE To quantify Metamorphopsia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to investigate the relationship between Metamorphopsia and foveal microstructure. METHODS This is prospective, consecutive, interventional study. Fifty-one eyes of MH were included. Severity of Metamorphopsia was quantified using the M-CHARTS and foveal microstructure was assessed with optical coherence tomography preoperatively and at 3 months, 6 months postoperatively. Based on the optical coherence tomography images, the authors quantified minimum and base diameters of MH, macular thickness, defect lengths of external limiting membrane, ellipsoid zone and interdigitation zone, and the area of intraretinal cysts within the fluid cuff. RESULTS Mean Metamorphopsia score was significantly improved from 0.82 to 0.44. Postoperative mean and horizontal Metamorphopsia scores were correlated with preoperative base diameters of MH, defect lengths of external limiting membrane, and the area of cysts in fluid cuff. Multiple regression analysis revealed that postoperative mean and horizontal Metamorphopsia scores were significantly positively relevant to the area of intraretinal cysts within the fluid cuff. Postoperative vertical Metamorphopsia score was also correlated with the area of intraretinal cysts within the fluid cuff. CONCLUSION Vitrectomy for MH improved Metamorphopsia. Postoperative Metamorphopsia was associated with the preoperative area of intraretinal cysts within the fluid cuff.

  • relationship between Metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema
    Graefes Archive for Clinical and Experimental Ophthalmology, 2016
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Masaharu Iida, Tetsuro Oshika
    Abstract:

    Purpose We aimed to investigate the relationship between the severity of Metamorphopsia and the foveal microstructure measured with spectral-domain optical coherence tomography (SD-OCT) in patients with cystoid macular edema caused by branch retinal vein occlusion (BRVO-CME).

Fumiki Okamoto - One of the best experts on this subject based on the ideXlab platform.

  • relationship between Metamorphopsia and inner retinal microstructure following intravitreal ranibizumab injection for branch retinal vein occlusion
    Scientific Reports, 2021
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Fumiki Okamoto, Shohei Morikawa, Tomoya Murakami, Syed Amal Hussnain, Tetsuro Oshika
    Abstract:

    To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO), and to assess the relationship between Metamorphopsia and inner retinal microstructure and other factors. Thirty-three treatment-naive eyes of 33 patients with macular edema caused by BRVO with at least 12 months of follow-up were included. The degree of Metamorphopsia was quantified using the M-CHARTS. Retinal microstructure was assessed with spectral-domain optical coherence tomography. Disorganization of the retinal inner layers (DRIL) at the first month after resolution of the macular edema (early DRIL) and at 12 months after treatment (after DRIL) was studied. Central retinal thickness (CRT), and status of the external limiting membrane as well as ellipsoid zone were also evaluated. IVR treatment significantly improved best-corrected visual acuity (BCVA) and CRT, but the mean Metamorphopsia score did not improve even after 12 months. Post-treatment Metamorphopsia scores showed a significant correlation with pre-treatment Metamorphopsia scores (P < 0.005), the extent of early DRIL (P < 0.05) and after DRIL (P < 0.05), and the number of injections (P < 0.05). Multivariate analysis revealed that the post-treatment mean Metamorphopsia score was significantly correlated with the pre-treatment mean Metamorphopsia score (P < 0.05). IVR treatment significantly improved BCVA and CRT, but not Metamorphopsia. Post-treatment Metamorphopsia scores were significantly associated with pre-treatment Metamorphopsia scores, the extent of DRIL, and the number of injections. Prognostic factor of Metamorphopsia was the degree of pre-treatment Metamorphopsia.

  • TIME COURSE OF CHANGES IN Metamorphopsia FOLLOWING INTRAVITREAL RANIBIZUMAB INJECTION FOR BRANCH RETINAL VEIN OCCLUSION.
    Retina, 2018
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Shohei Morikawa, Tetsuro Oshika
    Abstract:

    PURPOSE To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO) and to assess the relationship between retinal microstructure and Metamorphopsia. METHODS Subjects were 39 eyes of 39 patients with branch retinal vein occlusion. The severity of Metamorphopsia was quantified using the M-CHARTS before and 1, 2, 3, 4, 5, and 6 months after treatment. Based on optical coherence tomography (OCT) images, we assessed central retinal thickness (CRT) and status of the external limiting membrane (ELM) and ellipsoid zone (EZ). The association between retinal microstructure and Metamorphopsia was analyzed in 24 eyes with treatment-naive branch retinal vein occlusion. RESULTS Intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity (BCVA) and central retinal thickness (P < 0.0001, P < 0.0001, respectively), but Metamorphopsia did not improve by treatment. Posttreatment Metamorphopsia scores showed a significant correlation with duration of symptoms (P < 0.05) and pretreatment Metamorphopsia scores (P < 0.01). Posttreatment Metamorphopsia score was significantly worse in patients with disruption of external limiting membrane (P < 0.05). CONCLUSIONS In patients with branch retinal vein occlusion, intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity and central retinal thickness, but not Metamorphopsia. The severity of posttreatment Metamorphopsia was significantly associated with duration of symptoms, degree of pretreatment Metamorphopsia, and posttreatment integrity of external limiting membrane.

  • changes in Metamorphopsia and optical coherence tomography findings after successful retinal detachment surgery
    Retina-the Journal of Retinal and Vitreous Diseases, 2017
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    Purpose:To investigate changes in Metamorphopsia after rhegmatogenous retinal detachment surgery and to evaluate the relationship between Metamorphopsia and retinal microstructures assessed with optical coherence tomography.Methods:The study included 47 eyes of 47 patients undergoing retinal detachm

  • RELATIONSHIP BETWEEN Metamorphopsia AND INTRARETINAL CYSTS WITHIN THE FLUID CUFF AFTER SURGERY FOR IDIOPATHIC MACULAR HOLE.
    Retina, 2017
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    PURPOSE To quantify Metamorphopsia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to investigate the relationship between Metamorphopsia and foveal microstructure. METHODS This is prospective, consecutive, interventional study. Fifty-one eyes of MH were included. Severity of Metamorphopsia was quantified using the M-CHARTS and foveal microstructure was assessed with optical coherence tomography preoperatively and at 3 months, 6 months postoperatively. Based on the optical coherence tomography images, the authors quantified minimum and base diameters of MH, macular thickness, defect lengths of external limiting membrane, ellipsoid zone and interdigitation zone, and the area of intraretinal cysts within the fluid cuff. RESULTS Mean Metamorphopsia score was significantly improved from 0.82 to 0.44. Postoperative mean and horizontal Metamorphopsia scores were correlated with preoperative base diameters of MH, defect lengths of external limiting membrane, and the area of cysts in fluid cuff. Multiple regression analysis revealed that postoperative mean and horizontal Metamorphopsia scores were significantly positively relevant to the area of intraretinal cysts within the fluid cuff. Postoperative vertical Metamorphopsia score was also correlated with the area of intraretinal cysts within the fluid cuff. CONCLUSION Vitrectomy for MH improved Metamorphopsia. Postoperative Metamorphopsia was associated with the preoperative area of intraretinal cysts within the fluid cuff.

  • relationship between Metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema
    Graefes Archive for Clinical and Experimental Ophthalmology, 2016
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Masaharu Iida, Tetsuro Oshika
    Abstract:

    Purpose We aimed to investigate the relationship between the severity of Metamorphopsia and the foveal microstructure measured with spectral-domain optical coherence tomography (SD-OCT) in patients with cystoid macular edema caused by branch retinal vein occlusion (BRVO-CME).

Takahiro Hiraoka - One of the best experts on this subject based on the ideXlab platform.

  • relationship between Metamorphopsia and inner retinal microstructure following intravitreal ranibizumab injection for branch retinal vein occlusion
    Scientific Reports, 2021
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Fumiki Okamoto, Shohei Morikawa, Tomoya Murakami, Syed Amal Hussnain, Tetsuro Oshika
    Abstract:

    To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO), and to assess the relationship between Metamorphopsia and inner retinal microstructure and other factors. Thirty-three treatment-naive eyes of 33 patients with macular edema caused by BRVO with at least 12 months of follow-up were included. The degree of Metamorphopsia was quantified using the M-CHARTS. Retinal microstructure was assessed with spectral-domain optical coherence tomography. Disorganization of the retinal inner layers (DRIL) at the first month after resolution of the macular edema (early DRIL) and at 12 months after treatment (after DRIL) was studied. Central retinal thickness (CRT), and status of the external limiting membrane as well as ellipsoid zone were also evaluated. IVR treatment significantly improved best-corrected visual acuity (BCVA) and CRT, but the mean Metamorphopsia score did not improve even after 12 months. Post-treatment Metamorphopsia scores showed a significant correlation with pre-treatment Metamorphopsia scores (P < 0.005), the extent of early DRIL (P < 0.05) and after DRIL (P < 0.05), and the number of injections (P < 0.05). Multivariate analysis revealed that the post-treatment mean Metamorphopsia score was significantly correlated with the pre-treatment mean Metamorphopsia score (P < 0.05). IVR treatment significantly improved BCVA and CRT, but not Metamorphopsia. Post-treatment Metamorphopsia scores were significantly associated with pre-treatment Metamorphopsia scores, the extent of DRIL, and the number of injections. Prognostic factor of Metamorphopsia was the degree of pre-treatment Metamorphopsia.

  • TIME COURSE OF CHANGES IN Metamorphopsia FOLLOWING INTRAVITREAL RANIBIZUMAB INJECTION FOR BRANCH RETINAL VEIN OCCLUSION.
    Retina, 2018
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Shohei Morikawa, Tetsuro Oshika
    Abstract:

    PURPOSE To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO) and to assess the relationship between retinal microstructure and Metamorphopsia. METHODS Subjects were 39 eyes of 39 patients with branch retinal vein occlusion. The severity of Metamorphopsia was quantified using the M-CHARTS before and 1, 2, 3, 4, 5, and 6 months after treatment. Based on optical coherence tomography (OCT) images, we assessed central retinal thickness (CRT) and status of the external limiting membrane (ELM) and ellipsoid zone (EZ). The association between retinal microstructure and Metamorphopsia was analyzed in 24 eyes with treatment-naive branch retinal vein occlusion. RESULTS Intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity (BCVA) and central retinal thickness (P < 0.0001, P < 0.0001, respectively), but Metamorphopsia did not improve by treatment. Posttreatment Metamorphopsia scores showed a significant correlation with duration of symptoms (P < 0.05) and pretreatment Metamorphopsia scores (P < 0.01). Posttreatment Metamorphopsia score was significantly worse in patients with disruption of external limiting membrane (P < 0.05). CONCLUSIONS In patients with branch retinal vein occlusion, intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity and central retinal thickness, but not Metamorphopsia. The severity of posttreatment Metamorphopsia was significantly associated with duration of symptoms, degree of pretreatment Metamorphopsia, and posttreatment integrity of external limiting membrane.

  • changes in Metamorphopsia and optical coherence tomography findings after successful retinal detachment surgery
    Retina-the Journal of Retinal and Vitreous Diseases, 2017
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    Purpose:To investigate changes in Metamorphopsia after rhegmatogenous retinal detachment surgery and to evaluate the relationship between Metamorphopsia and retinal microstructures assessed with optical coherence tomography.Methods:The study included 47 eyes of 47 patients undergoing retinal detachm

  • RELATIONSHIP BETWEEN Metamorphopsia AND INTRARETINAL CYSTS WITHIN THE FLUID CUFF AFTER SURGERY FOR IDIOPATHIC MACULAR HOLE.
    Retina, 2017
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    PURPOSE To quantify Metamorphopsia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to investigate the relationship between Metamorphopsia and foveal microstructure. METHODS This is prospective, consecutive, interventional study. Fifty-one eyes of MH were included. Severity of Metamorphopsia was quantified using the M-CHARTS and foveal microstructure was assessed with optical coherence tomography preoperatively and at 3 months, 6 months postoperatively. Based on the optical coherence tomography images, the authors quantified minimum and base diameters of MH, macular thickness, defect lengths of external limiting membrane, ellipsoid zone and interdigitation zone, and the area of intraretinal cysts within the fluid cuff. RESULTS Mean Metamorphopsia score was significantly improved from 0.82 to 0.44. Postoperative mean and horizontal Metamorphopsia scores were correlated with preoperative base diameters of MH, defect lengths of external limiting membrane, and the area of cysts in fluid cuff. Multiple regression analysis revealed that postoperative mean and horizontal Metamorphopsia scores were significantly positively relevant to the area of intraretinal cysts within the fluid cuff. Postoperative vertical Metamorphopsia score was also correlated with the area of intraretinal cysts within the fluid cuff. CONCLUSION Vitrectomy for MH improved Metamorphopsia. Postoperative Metamorphopsia was associated with the preoperative area of intraretinal cysts within the fluid cuff.

  • relationship between Metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema
    Graefes Archive for Clinical and Experimental Ophthalmology, 2016
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Masaharu Iida, Tetsuro Oshika
    Abstract:

    Purpose We aimed to investigate the relationship between the severity of Metamorphopsia and the foveal microstructure measured with spectral-domain optical coherence tomography (SD-OCT) in patients with cystoid macular edema caused by branch retinal vein occlusion (BRVO-CME).

Yoshifumi Okamoto - One of the best experts on this subject based on the ideXlab platform.

  • TIME COURSE OF CHANGES IN Metamorphopsia FOLLOWING INTRAVITREAL RANIBIZUMAB INJECTION FOR BRANCH RETINAL VEIN OCCLUSION.
    Retina, 2018
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Shohei Morikawa, Tetsuro Oshika
    Abstract:

    PURPOSE To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO) and to assess the relationship between retinal microstructure and Metamorphopsia. METHODS Subjects were 39 eyes of 39 patients with branch retinal vein occlusion. The severity of Metamorphopsia was quantified using the M-CHARTS before and 1, 2, 3, 4, 5, and 6 months after treatment. Based on optical coherence tomography (OCT) images, we assessed central retinal thickness (CRT) and status of the external limiting membrane (ELM) and ellipsoid zone (EZ). The association between retinal microstructure and Metamorphopsia was analyzed in 24 eyes with treatment-naive branch retinal vein occlusion. RESULTS Intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity (BCVA) and central retinal thickness (P < 0.0001, P < 0.0001, respectively), but Metamorphopsia did not improve by treatment. Posttreatment Metamorphopsia scores showed a significant correlation with duration of symptoms (P < 0.05) and pretreatment Metamorphopsia scores (P < 0.01). Posttreatment Metamorphopsia score was significantly worse in patients with disruption of external limiting membrane (P < 0.05). CONCLUSIONS In patients with branch retinal vein occlusion, intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity and central retinal thickness, but not Metamorphopsia. The severity of posttreatment Metamorphopsia was significantly associated with duration of symptoms, degree of pretreatment Metamorphopsia, and posttreatment integrity of external limiting membrane.

  • changes in Metamorphopsia and optical coherence tomography findings after successful retinal detachment surgery
    Retina-the Journal of Retinal and Vitreous Diseases, 2017
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    Purpose:To investigate changes in Metamorphopsia after rhegmatogenous retinal detachment surgery and to evaluate the relationship between Metamorphopsia and retinal microstructures assessed with optical coherence tomography.Methods:The study included 47 eyes of 47 patients undergoing retinal detachm

  • RELATIONSHIP BETWEEN Metamorphopsia AND INTRARETINAL CYSTS WITHIN THE FLUID CUFF AFTER SURGERY FOR IDIOPATHIC MACULAR HOLE.
    Retina, 2017
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    PURPOSE To quantify Metamorphopsia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to investigate the relationship between Metamorphopsia and foveal microstructure. METHODS This is prospective, consecutive, interventional study. Fifty-one eyes of MH were included. Severity of Metamorphopsia was quantified using the M-CHARTS and foveal microstructure was assessed with optical coherence tomography preoperatively and at 3 months, 6 months postoperatively. Based on the optical coherence tomography images, the authors quantified minimum and base diameters of MH, macular thickness, defect lengths of external limiting membrane, ellipsoid zone and interdigitation zone, and the area of intraretinal cysts within the fluid cuff. RESULTS Mean Metamorphopsia score was significantly improved from 0.82 to 0.44. Postoperative mean and horizontal Metamorphopsia scores were correlated with preoperative base diameters of MH, defect lengths of external limiting membrane, and the area of cysts in fluid cuff. Multiple regression analysis revealed that postoperative mean and horizontal Metamorphopsia scores were significantly positively relevant to the area of intraretinal cysts within the fluid cuff. Postoperative vertical Metamorphopsia score was also correlated with the area of intraretinal cysts within the fluid cuff. CONCLUSION Vitrectomy for MH improved Metamorphopsia. Postoperative Metamorphopsia was associated with the preoperative area of intraretinal cysts within the fluid cuff.

  • relationship between Metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema
    Graefes Archive for Clinical and Experimental Ophthalmology, 2016
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Masaharu Iida, Tetsuro Oshika
    Abstract:

    Purpose We aimed to investigate the relationship between the severity of Metamorphopsia and the foveal microstructure measured with spectral-domain optical coherence tomography (SD-OCT) in patients with cystoid macular edema caused by branch retinal vein occlusion (BRVO-CME).

  • inner nuclear layer thickness as a prognostic factor for Metamorphopsia after epiretinal membrane surgery
    Retina-the Journal of Retinal and Vitreous Diseases, 2015
    Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro Oshika
    Abstract:

    Purpose:To evaluate prognostic factors for Metamorphopsia in patients undergoing vitrectomy for epiretinal membrane using spectral domain optical coherence tomography.Methods:This study included 53 eyes of 53 patients undergoing vitrectomy for idiopathic epiretinal membrane. The authors examined vis

Yoshimi Sugiura - One of the best experts on this subject based on the ideXlab platform.

  • relationship between Metamorphopsia and inner retinal microstructure following intravitreal ranibizumab injection for branch retinal vein occlusion
    Scientific Reports, 2021
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Fumiki Okamoto, Shohei Morikawa, Tomoya Murakami, Syed Amal Hussnain, Tetsuro Oshika
    Abstract:

    To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO), and to assess the relationship between Metamorphopsia and inner retinal microstructure and other factors. Thirty-three treatment-naive eyes of 33 patients with macular edema caused by BRVO with at least 12 months of follow-up were included. The degree of Metamorphopsia was quantified using the M-CHARTS. Retinal microstructure was assessed with spectral-domain optical coherence tomography. Disorganization of the retinal inner layers (DRIL) at the first month after resolution of the macular edema (early DRIL) and at 12 months after treatment (after DRIL) was studied. Central retinal thickness (CRT), and status of the external limiting membrane as well as ellipsoid zone were also evaluated. IVR treatment significantly improved best-corrected visual acuity (BCVA) and CRT, but the mean Metamorphopsia score did not improve even after 12 months. Post-treatment Metamorphopsia scores showed a significant correlation with pre-treatment Metamorphopsia scores (P < 0.005), the extent of early DRIL (P < 0.05) and after DRIL (P < 0.05), and the number of injections (P < 0.05). Multivariate analysis revealed that the post-treatment mean Metamorphopsia score was significantly correlated with the pre-treatment mean Metamorphopsia score (P < 0.05). IVR treatment significantly improved BCVA and CRT, but not Metamorphopsia. Post-treatment Metamorphopsia scores were significantly associated with pre-treatment Metamorphopsia scores, the extent of DRIL, and the number of injections. Prognostic factor of Metamorphopsia was the degree of pre-treatment Metamorphopsia.

  • TIME COURSE OF CHANGES IN Metamorphopsia FOLLOWING INTRAVITREAL RANIBIZUMAB INJECTION FOR BRANCH RETINAL VEIN OCCLUSION.
    Retina, 2018
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Shohei Morikawa, Tetsuro Oshika
    Abstract:

    PURPOSE To evaluate the effects of intravitreal ranibizumab injection (IVR) on Metamorphopsia in patients with branch retinal vein occlusion (BRVO) and to assess the relationship between retinal microstructure and Metamorphopsia. METHODS Subjects were 39 eyes of 39 patients with branch retinal vein occlusion. The severity of Metamorphopsia was quantified using the M-CHARTS before and 1, 2, 3, 4, 5, and 6 months after treatment. Based on optical coherence tomography (OCT) images, we assessed central retinal thickness (CRT) and status of the external limiting membrane (ELM) and ellipsoid zone (EZ). The association between retinal microstructure and Metamorphopsia was analyzed in 24 eyes with treatment-naive branch retinal vein occlusion. RESULTS Intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity (BCVA) and central retinal thickness (P < 0.0001, P < 0.0001, respectively), but Metamorphopsia did not improve by treatment. Posttreatment Metamorphopsia scores showed a significant correlation with duration of symptoms (P < 0.05) and pretreatment Metamorphopsia scores (P < 0.01). Posttreatment Metamorphopsia score was significantly worse in patients with disruption of external limiting membrane (P < 0.05). CONCLUSIONS In patients with branch retinal vein occlusion, intravitreal ranibizumab injection treatment significantly improved best-corrected visual acuity and central retinal thickness, but not Metamorphopsia. The severity of posttreatment Metamorphopsia was significantly associated with duration of symptoms, degree of pretreatment Metamorphopsia, and posttreatment integrity of external limiting membrane.

  • changes in Metamorphopsia and optical coherence tomography findings after successful retinal detachment surgery
    Retina-the Journal of Retinal and Vitreous Diseases, 2017
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    Purpose:To investigate changes in Metamorphopsia after rhegmatogenous retinal detachment surgery and to evaluate the relationship between Metamorphopsia and retinal microstructures assessed with optical coherence tomography.Methods:The study included 47 eyes of 47 patients undergoing retinal detachm

  • RELATIONSHIP BETWEEN Metamorphopsia AND INTRARETINAL CYSTS WITHIN THE FLUID CUFF AFTER SURGERY FOR IDIOPATHIC MACULAR HOLE.
    Retina, 2017
    Co-Authors: Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro Oshika
    Abstract:

    PURPOSE To quantify Metamorphopsia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to investigate the relationship between Metamorphopsia and foveal microstructure. METHODS This is prospective, consecutive, interventional study. Fifty-one eyes of MH were included. Severity of Metamorphopsia was quantified using the M-CHARTS and foveal microstructure was assessed with optical coherence tomography preoperatively and at 3 months, 6 months postoperatively. Based on the optical coherence tomography images, the authors quantified minimum and base diameters of MH, macular thickness, defect lengths of external limiting membrane, ellipsoid zone and interdigitation zone, and the area of intraretinal cysts within the fluid cuff. RESULTS Mean Metamorphopsia score was significantly improved from 0.82 to 0.44. Postoperative mean and horizontal Metamorphopsia scores were correlated with preoperative base diameters of MH, defect lengths of external limiting membrane, and the area of cysts in fluid cuff. Multiple regression analysis revealed that postoperative mean and horizontal Metamorphopsia scores were significantly positively relevant to the area of intraretinal cysts within the fluid cuff. Postoperative vertical Metamorphopsia score was also correlated with the area of intraretinal cysts within the fluid cuff. CONCLUSION Vitrectomy for MH improved Metamorphopsia. Postoperative Metamorphopsia was associated with the preoperative area of intraretinal cysts within the fluid cuff.

  • relationship between Metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema
    Graefes Archive for Clinical and Experimental Ophthalmology, 2016
    Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Masaharu Iida, Tetsuro Oshika
    Abstract:

    Purpose We aimed to investigate the relationship between the severity of Metamorphopsia and the foveal microstructure measured with spectral-domain optical coherence tomography (SD-OCT) in patients with cystoid macular edema caused by branch retinal vein occlusion (BRVO-CME).