The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
Issam Hanna - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of the Tricyclic Core of Colchicine via a Dienyne Tandem Ring-Closing Metathesis Reaction
Organic Letters, 2007Co-Authors: François-didier Boyer† And, Issam HannaAbstract:The synthesis of the tricyclic framework of colchicine has been achieved using a tandem ring-closing Metathesis Reaction of dienynes as the key step. In this process, both seven-membered rings B and C were formed in one step. Oxidation of tertiary allylic alcohol derived from the tandem Metathesis product furnished an intermediate in the total synthesis of colchicine.
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Synthesis of the tricyclic core of colchicine via a dienyne tandem ring-closing Metathesis Reaction
Organic Letters, 2007Co-Authors: François-didier Boyer, Issam HannaAbstract:The synthesis of the tricyclic framework of colchicine has been achieved using a tandem ring-closing Metathesis Reaction of dienynes as the key step. In this process, both seven-membered rings B and C were formed in one step. Oxidation of tertiary allylic alcohol derived from the tandem Metathesis product furnished an intermediate in the total synthesis of colchicine. © 2007 American Chemical Society.
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Synthesis of a highly functionalized tricyclic ring system related to guanacastepene via a tandem ring-closing Metathesis Reaction
Tetrahedron Letters, 2002Co-Authors: François-didier Boyer, Issam HannaAbstract:A new approach to a highly functionalized 5,7,6-tricyclic core structure of guanacastepene has been developed using the tandem ring-closing Metathesis Reaction of dienynes as the key step. © 2002 Elsevier Science Ltd. All rights reserved.
François-didier Boyer - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of the tricyclic core of colchicine via a dienyne tandem ring-closing Metathesis Reaction
Organic Letters, 2007Co-Authors: François-didier Boyer, Issam HannaAbstract:The synthesis of the tricyclic framework of colchicine has been achieved using a tandem ring-closing Metathesis Reaction of dienynes as the key step. In this process, both seven-membered rings B and C were formed in one step. Oxidation of tertiary allylic alcohol derived from the tandem Metathesis product furnished an intermediate in the total synthesis of colchicine. © 2007 American Chemical Society.
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Synthesis of a highly functionalized tricyclic ring system related to guanacastepene via a tandem ring-closing Metathesis Reaction
Tetrahedron Letters, 2002Co-Authors: François-didier Boyer, Issam HannaAbstract:A new approach to a highly functionalized 5,7,6-tricyclic core structure of guanacastepene has been developed using the tandem ring-closing Metathesis Reaction of dienynes as the key step. © 2002 Elsevier Science Ltd. All rights reserved.
James Samanen - One of the best experts on this subject based on the ideXlab platform.
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Combinatorial chemistry. Use of an intramolecular ruthenium catalyzed olefin/alkyne Metathesis Reaction in tandem with a Diels-Alder cycloaddition Reaction to construct functionalized hexahydroisoindoles
Tetrahedron Letters, 1998Co-Authors: Dirk A. Heerding, Dennis T. Takata, Chet Kwon, William F. Huffman, James SamanenAbstract:Abstract We show here the first example of a ruthenium catalyzed ene-yne Metathesis Reaction in tandem with a Diels-Alder cycloaddition Reaction to efficiently form highly substituted hexahydroisoindole ring systems on Wang resin. This approach was used to prepare a 4200 membered combinatorial library.
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combinatorial chemistry use of an intramolecular ruthenium catalyzed olefin alkyne Metathesis Reaction in tandem with a diels alder cycloaddition Reaction to construct functionalized hexahydroisoindoles
Tetrahedron Letters, 1998Co-Authors: Dirk A. Heerding, Dennis T. Takata, Chet Kwon, William F. Huffman, James SamanenAbstract:Abstract We show here the first example of a ruthenium catalyzed ene-yne Metathesis Reaction in tandem with a Diels-Alder cycloaddition Reaction to efficiently form highly substituted hexahydroisoindole ring systems on Wang resin. This approach was used to prepare a 4200 membered combinatorial library.
Frederic Lamaty - One of the best experts on this subject based on the ideXlab platform.
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preparation of nhc ruthenium complexes and their catalytic activity in Metathesis Reaction
Coordination Chemistry Reviews, 2007Co-Authors: Evelina Colacino, Jean Martinez, Frederic LamatyAbstract:Abstract A detailed overview on the synthesis of four-, five- and six-membered, saturated and unsaturated N -heterocyclic carbenes used in the preparation of their corresponding ruthenium complexes (Grubbs’ second-generation, Fischer-type, Hoveyda–Grubbs, homo and hetero-bimetallic) is presented both in solution and on solid support. The catalytic activity of the different complexes in ruthenium-catalyzed Metathesis Reaction is compared and explained by their structural features.
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Preparation of NHC-ruthenium complexes and their catalytic activity in Metathesis Reaction
Coordination Chemistry Reviews, 2007Co-Authors: Evelina Colacino, Jean Martinez, Frederic LamatyAbstract:A detailed overview on the synthesis of four-, five- and six-membered, saturated and unsaturated N-heterocyclic carbenes used in the preparation of their corresponding ruthenium complexes (Grubbs' second-generation, Fischer-type, Hoveyda-Grubbs, homo and hetero-bimetallic) is presented both in solution and on solid support. The catalytic activity of the different complexes in ruthenium-catalyzed Metathesis Reaction is compared and explained by their structural features. (c) 2006 Elsevier B.V. All rights reserved.
Carlmagnus Andersson - One of the best experts on this subject based on the ideXlab platform.
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solution phase combinatorial synthesis via the olefin Metathesis Reaction
Bioorganic & Medicinal Chemistry Letters, 1997Co-Authors: Dale L Boger, Wenying Chai, Rachel S Ozer, Carlmagnus AnderssonAbstract:Abstract The preparation of C2-symmetric and unsymmetric chemical libraries by solution-phase techniques including the use of the olefin Metathesis Reaction to join and combinatorially randomize the length of a linking tether is detailed.