The Experts below are selected from a list of 618 Experts worldwide ranked by ideXlab platform

Alexander Deiters - One of the best experts on this subject based on the ideXlab platform.

  • synthesis and investigation of the 5 formylcytidine modified anticodon stem and loop of the human mitochondrial tRNAmet
    Nucleic Acids Research, 2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA (hmtRNAMetCAU) has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f5C34). The role of this modification in (hmtRNAMetCAU) for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA's anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA's anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

  • Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human
    2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA ðhmtRNA Met Þ has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f 5 C34). The role of this modification in hmtRNA Met for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA’s anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA’s anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

Hrvoje Lusic - One of the best experts on this subject based on the ideXlab platform.

  • synthesis and investigation of the 5 formylcytidine modified anticodon stem and loop of the human mitochondrial tRNAmet
    Nucleic Acids Research, 2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA (hmtRNAMetCAU) has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f5C34). The role of this modification in (hmtRNAMetCAU) for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA's anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA's anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

  • Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human
    2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA ðhmtRNA Met Þ has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f 5 C34). The role of this modification in hmtRNA Met for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA’s anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA’s anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

Estella M Gustilo - One of the best experts on this subject based on the ideXlab platform.

  • synthesis and investigation of the 5 formylcytidine modified anticodon stem and loop of the human mitochondrial tRNAmet
    Nucleic Acids Research, 2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA (hmtRNAMetCAU) has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f5C34). The role of this modification in (hmtRNAMetCAU) for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA's anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA's anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

  • Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human
    2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA ðhmtRNA Met Þ has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f 5 C34). The role of this modification in hmtRNA Met for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA’s anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA’s anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

Franck A P Vendeix - One of the best experts on this subject based on the ideXlab platform.

  • synthesis and investigation of the 5 formylcytidine modified anticodon stem and loop of the human mitochondrial tRNAmet
    Nucleic Acids Research, 2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA (hmtRNAMetCAU) has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f5C34). The role of this modification in (hmtRNAMetCAU) for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA's anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA's anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

  • Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human
    2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA ðhmtRNA Met Þ has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f 5 C34). The role of this modification in hmtRNA Met for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA’s anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA’s anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

Robert J Kaiser - One of the best experts on this subject based on the ideXlab platform.

  • synthesis and investigation of the 5 formylcytidine modified anticodon stem and loop of the human mitochondrial tRNAmet
    Nucleic Acids Research, 2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA (hmtRNAMetCAU) has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f5C34). The role of this modification in (hmtRNAMetCAU) for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA's anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA's anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.

  • Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human
    2008
    Co-Authors: Hrvoje Lusic, Estella M Gustilo, Franck A P Vendeix, Robert J Kaiser, Michael O Delaney, William D Graham, Virginia A Moye, William A Cantara, Paul F Agris, Alexander Deiters
    Abstract:

    Human mitochondrial Methionine Transfer RNA ðhmtRNA Met Þ has a unique post-transcriptional modification, 5-formylcytidine, at the wobble position-34 (f 5 C34). The role of this modification in hmtRNA Met for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. We report the first synthesis and analyses of the tRNA’s anticodon stem and loop domain containing the 5-formylcytidine modification. The modification contributes to the tRNA’s anticodon domain structure, thermodynamic properties and its ability to bind codons AUA and AUG in translational initiation and elongation.