The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform

Tejraj M. Aminabhavi - One of the best experts on this subject based on the ideXlab platform.

Yongchuan Wong - One of the best experts on this subject based on the ideXlab platform.

  • lignans isolated from campylotropis hirtella franch schindl decreased prostate specific antigen and androgen receptor expression in lncap cells
    Journal of Agricultural and Food Chemistry, 2008
    Co-Authors: Xianghong Wang, Mingtat Ling, Naili Wang, Yongchuan Wong
    Abstract:

    Accumulating epidemiological data suggest that Asian men have lower incidences of prostate cancer and benign prostate hyperplasia (BPH) compared with American and European populations and may have benefited from their higher intake of phytoestrogens in their diet. However, how these phytochemicals affect prostatic diseases is still unclear. In this study, we isolated six lignans from a plant, Campylotropis hirtella (Franch.) Schindl., which has been used as a folk medicine for treatment of BPH in China, through bioassay guided fractionation. They were dehydrodiconiferyl alcohol (C1), 4-[(-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl)methyl]-5-Methoxybenzene-1,3-diol (C2), erythro-guaiacylglycerol-β-O-4′-coniferyl ether (C3), threo-guaiacylglycerol-β-O-4′-coniferyl ether (C4), secoisolariciresinol (C5), and prupaside (C6), where C2 was identified as a new lignan analog. Their IC50 values for inhibition of prostate specific antigen (PSA) secretion were 19, 45, 110, 128, 137, and 186 μM, respectively, from C1 to ...

  • lignans isolated from campylotropis hirtella franch schindl decreased prostate specific antigen and androgen receptor expression in lncap cells
    Journal of Agricultural and Food Chemistry, 2008
    Co-Authors: Xianghong Wang, Mingtat Ling, Naili Wang, Yongchuan Wong
    Abstract:

    Accumulating epidemiological data suggest that Asian men have lower incidences of prostate cancer and benign prostate hyperplasia (BPH) compared with American and European populations and may have benefited from their higher intake of phytoestrogens in their diet. However, how these phytochemicals affect prostatic diseases is still unclear. In this study, we isolated six lignans from a plant, Campylotropis hirtella (Franch.) Schindl., which has been used as a folk medicine for treatment of BPH in China, through bioassay guided fractionation. They were dehydrodiconiferyl alcohol (C1), 4-[(-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl)methyl]-5-Methoxybenzene-1,3-diol (C2), erythro-guaiacylglycerol-β-O-4′-coniferyl ether (C3), threo-guaiacylglycerol-β-O-4′-coniferyl ether (C4), secoisolariciresinol (C5), and prupaside (C6), where C2 was identified as a new lignan analog. Their IC50 values for inhibition of prostate specific antigen (PSA) secretion were 19, 45, 110, 128, 137, and 186 μM, respectively, from C1 to ...

Xianghong Wang - One of the best experts on this subject based on the ideXlab platform.

  • lignans isolated from campylotropis hirtella franch schindl decreased prostate specific antigen and androgen receptor expression in lncap cells
    Journal of Agricultural and Food Chemistry, 2008
    Co-Authors: Xianghong Wang, Mingtat Ling, Naili Wang, Yongchuan Wong
    Abstract:

    Accumulating epidemiological data suggest that Asian men have lower incidences of prostate cancer and benign prostate hyperplasia (BPH) compared with American and European populations and may have benefited from their higher intake of phytoestrogens in their diet. However, how these phytochemicals affect prostatic diseases is still unclear. In this study, we isolated six lignans from a plant, Campylotropis hirtella (Franch.) Schindl., which has been used as a folk medicine for treatment of BPH in China, through bioassay guided fractionation. They were dehydrodiconiferyl alcohol (C1), 4-[(-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl)methyl]-5-Methoxybenzene-1,3-diol (C2), erythro-guaiacylglycerol-β-O-4′-coniferyl ether (C3), threo-guaiacylglycerol-β-O-4′-coniferyl ether (C4), secoisolariciresinol (C5), and prupaside (C6), where C2 was identified as a new lignan analog. Their IC50 values for inhibition of prostate specific antigen (PSA) secretion were 19, 45, 110, 128, 137, and 186 μM, respectively, from C1 to ...

  • lignans isolated from campylotropis hirtella franch schindl decreased prostate specific antigen and androgen receptor expression in lncap cells
    Journal of Agricultural and Food Chemistry, 2008
    Co-Authors: Xianghong Wang, Mingtat Ling, Naili Wang, Yongchuan Wong
    Abstract:

    Accumulating epidemiological data suggest that Asian men have lower incidences of prostate cancer and benign prostate hyperplasia (BPH) compared with American and European populations and may have benefited from their higher intake of phytoestrogens in their diet. However, how these phytochemicals affect prostatic diseases is still unclear. In this study, we isolated six lignans from a plant, Campylotropis hirtella (Franch.) Schindl., which has been used as a folk medicine for treatment of BPH in China, through bioassay guided fractionation. They were dehydrodiconiferyl alcohol (C1), 4-[(-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl)methyl]-5-Methoxybenzene-1,3-diol (C2), erythro-guaiacylglycerol-β-O-4′-coniferyl ether (C3), threo-guaiacylglycerol-β-O-4′-coniferyl ether (C4), secoisolariciresinol (C5), and prupaside (C6), where C2 was identified as a new lignan analog. Their IC50 values for inhibition of prostate specific antigen (PSA) secretion were 19, 45, 110, 128, 137, and 186 μM, respectively, from C1 to ...

M. I. Aralaguppi - One of the best experts on this subject based on the ideXlab platform.

Kamalika Banerjee - One of the best experts on this subject based on the ideXlab platform.