The Experts below are selected from a list of 237 Experts worldwide ranked by ideXlab platform

Farabi Hussain - One of the best experts on this subject based on the ideXlab platform.

Jung Hyun Choi - One of the best experts on this subject based on the ideXlab platform.

Marcus B. Nashelsky - One of the best experts on this subject based on the ideXlab platform.

  • Cholesterol granulomas of the lungs associated with Microangiopathic Hemolytic Anemia and thrombocytopenia in pulmonary hypertension.
    Archives of pathology & laboratory medicine, 2000
    Co-Authors: Edgar G. Fischer, John Marek, Amy Morris, Marcus B. Nashelsky
    Abstract:

    Abstract Cholesterol granulomas unrelated to endogenous lipoid pneumonia, pulmonary alveolar proteinosis, or cholesterol pneumonia are a rare finding during pneumectomy or autopsy. They have been occasionally reported in association with pulmonary hypertension. We report a case where these lesions were associated with long-standing pulmonary hypertension and Microangiopathic Hemolytic Anemia and thrombocytopenia. Plexiform lesions were present in the pulmonary vasculature secondary to pulmonary hypertension, causing hemolysis and thrombocytopenia. We suggest that destruction of red blood cells and platelets could provide membrane lipids that are taken up by phagocytic cells, which promotes the formation of these cholesterol deposits.

Young Joo Park - One of the best experts on this subject based on the ideXlab platform.

Edgar G. Fischer - One of the best experts on this subject based on the ideXlab platform.

  • Cholesterol granulomas of the lungs associated with Microangiopathic Hemolytic Anemia and thrombocytopenia in pulmonary hypertension.
    Archives of pathology & laboratory medicine, 2000
    Co-Authors: Edgar G. Fischer, John Marek, Amy Morris, Marcus B. Nashelsky
    Abstract:

    Abstract Cholesterol granulomas unrelated to endogenous lipoid pneumonia, pulmonary alveolar proteinosis, or cholesterol pneumonia are a rare finding during pneumectomy or autopsy. They have been occasionally reported in association with pulmonary hypertension. We report a case where these lesions were associated with long-standing pulmonary hypertension and Microangiopathic Hemolytic Anemia and thrombocytopenia. Plexiform lesions were present in the pulmonary vasculature secondary to pulmonary hypertension, causing hemolysis and thrombocytopenia. We suggest that destruction of red blood cells and platelets could provide membrane lipids that are taken up by phagocytic cells, which promotes the formation of these cholesterol deposits.