The Experts below are selected from a list of 168 Experts worldwide ranked by ideXlab platform

Farzad Hadaegh - One of the best experts on this subject based on the ideXlab platform.

  • Prehypertension Tsunami: A Decade Follow-Up of an Iranian Adult Population
    PLOS ONE, 2015
    Co-Authors: Farzad Hadaegh, Davood Khalili, Mitra Hasheminia, Hengameh Abdi, Mohammadreza Bozorgmanesh, Banafsheh Arshi, Fereidoun Azizi
    Abstract:

    Objective Prehypertension is associated with cardiovascular disease (CVD). There is no study to examine the incidence and risk factors of prehypertension in a sex stratified setting. The aim of this study was to examine the effect modification of sex for different risk factors which predicts the progression from normotension to prehypertension in a Middle East Population-based cohort, during a median follow-up of 9.2 years. Methods A multivariate Cox analysis was performed among 1466 and 2131 Iranian men and women, respectively, who were free of prehypertension, hypertension, CVD and diabetes at baseline and free of incident hypertension without preceding prehypertension at follow-up. Incident prehypertension at follow-up was defined as systolic blood pressure (SBP) of 120–139 mmHg and/or diastolic blood pressure (DBP) of 80–89 mmHg. Results Overall, 1440 new cases of prehypertension were identified resulting in an incidence rate of 593/10000 person-years; the corresponding values for women and men were 489/10000 and 764/10000person-years, respectively. There were significant interactions between gender with age, DBP, waist-to-hip-ratio (WHpR) and estimated glomerular filtration rate (eGFR) (all P-values

  • distribution of ideal cardiovascular health in a community based cohort of Middle East Population
    Annals of Saudi Medicine, 2014
    Co-Authors: Mariam Maleki Moghaddam, Fereidoun Azizi, Reza Mohebi, Firoozeh Hosseini, Mojtaba Lotfaliany, Navid Saadat, Farzad Hadaegh
    Abstract:

    BACKGROUND AND OBJECTIVES: To improve cardiovascular (CV) health of American Population, the American Heart Association (AHA) developed definitions of ideal, intermediate, and poor CV health based ...

  • does an electrocardiogram add predictive value to the rose angina questionnaire for future coronary heart disease 10 year follow up in a Middle East Population
    Journal of Epidemiology and Community Health, 2012
    Co-Authors: Davood Khalili, Farzad Hadaegh, Nooshin Fahimfar, Farhad Sheikholeslami, Gita Shafiee, Arash Ghanbarian, Fereidoun Azizi
    Abstract:

    Background To evaluate the power of abnormal resting ECG versus Rose Questionnaire angina and its additive value in predicting 10-year coronary heart disease (CHD) risk in an Iranian urban Population with high prevalence of CHD. Methods There were 5101 subjects ≥30 years (2900 women), free of CHD at baseline; they were categorised in to four groups according to their Rose Angina and ECG status for ischaemia as Rose−/ECG−, Rose+/ECG−, Rose−/ECG+ and Rose+/ECG+. HR of CHD was estimated using Cox regression analysis, given Rose−/ECG− as the reference. The authors used Akaike information criterion, C-index and integrated discrimination improvement indices to evaluate the prognostic value of ECG when would be added to Rose Questionnaire. Results During follow-up, 387 CHD events (169 women) were observed. Multivariate analysis showed a HR of 2.59 (95% CI 1.71 to 3.91) and 2.26 (1.48 to 3.44) for Rose+/ECG− group in men and women, respectively. These figures for Rose−/ECG+ were 1.36 (0.90 to 2.05) in men and 2.09 (1.40 to 3.12) in women. There was no any interaction between Rose Questionnaire and gender to predict incident CHD, in age-adjusted analysis. Akaike information criterion, C-index and relative integrated discrimination improvement did not show any difference between models including Rose alone and Rose plus ECG to predict CHD events especially in men. Conclusions Rose Questionnaire as a simple screening tool is equally important to predict incident CHD in both genders. Adding abnormal ECG to angina did not culminate in higher risk for future CHD events.

  • Incidence of chronic kidney disease and its risk factors, results of over 10 year follow up in an Iranian cohort.
    PLOS ONE, 2012
    Co-Authors: Maryam Tohidi, Davood Khalili, Fereidoun Azizi, Reza Mohebi, Mitra Hasheminia, Farhad Hosseinpanah, Babak Yazdani, Amir Ahmad Nasiri, Farzad Hadaegh
    Abstract:

    To examine, the predictors of incident chronic kidney disease (CKD) in a community-based cohort of Middle East Population, during a mean follow-up of 9.9 years. In a sample of 3313 non-CKD Iranian adults ≥20 years the estimated glomerular filtration rate (eGFR) was calculated at baseline and at three year intervals during three consecutive phases. The eGFR 2% of individuals develops CKD each year. Our findings confirmed that sex- specific risk predictors should be considered in primary prevention for incident CKD.

  • adolescent lipoprotein classifications according to national health and nutrition examination survey nhanes vs national cholesterol education program ncep for predicting abnormal lipid levels in adulthood in a Middle East Population
    Lipids in Health and Disease, 2012
    Co-Authors: Masumeh Hatami, Davood Khalili, Fereidoun Azizi, Reza Mohebi, Maryam Tohidi, Farzad Hadaegh
    Abstract:

    Background: To compare the predictive ability of adolescent lipoprotein classification using the National Examination Survey (NHANES) cut points and those of the National Cholesterol Education Program (NCEP) for predicting abnormal levels in adulthood. Method: From 1032 adolescents, aged 14–19 years, participants of the Tehran Lipid and Glucose Study, all lipid measures were determined at baseline and again after 6 years. Multivariable Odds Ratios (ORs) were calculated for borderline and high categories of lipids to predict dyslipidemia in adulthood, considering the normal level as a reference. Area under the receiving characteristics curve (AUC) was used to assess the predictive ability of each adolescent lipid classification. Result: Applying the NCEP classification, the prevalences of high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides and low high density lipoprotein cholesterol (HDL-C) in males were 12.1%, 12.9%, 26.1% and 34.2% respectively; in females the corresponding prevalences were 15.4%, 17.9%, 21.4% and 25.0%, respectively. Using NHANES cut points, the prevalence of high TC, LDL-C and triglycerides were lower, than those defined by NCEP; the ORs of high categories of lipids (defined by NHANES) were higher than ORs based on the NECP classification, except for HDL-C. For all lipid measures, both classifications had similar predictive abilities, except for TC/HDL-C, which had higher predictive power applying the NHANES classification rather than the NCEP one (AUC 71% vs. 68%, respectively). Conclusion: No differences were found between NCEP and NHANES classifications for prediction of adult dyslipidemia, except for TC/HDL-C. Because of their simple application, NCEP cut points can be used in clinical settings.

Fereidoun Azizi - One of the best experts on this subject based on the ideXlab platform.

  • Prehypertension Tsunami: A Decade Follow-Up of an Iranian Adult Population
    PLOS ONE, 2015
    Co-Authors: Farzad Hadaegh, Davood Khalili, Mitra Hasheminia, Hengameh Abdi, Mohammadreza Bozorgmanesh, Banafsheh Arshi, Fereidoun Azizi
    Abstract:

    Objective Prehypertension is associated with cardiovascular disease (CVD). There is no study to examine the incidence and risk factors of prehypertension in a sex stratified setting. The aim of this study was to examine the effect modification of sex for different risk factors which predicts the progression from normotension to prehypertension in a Middle East Population-based cohort, during a median follow-up of 9.2 years. Methods A multivariate Cox analysis was performed among 1466 and 2131 Iranian men and women, respectively, who were free of prehypertension, hypertension, CVD and diabetes at baseline and free of incident hypertension without preceding prehypertension at follow-up. Incident prehypertension at follow-up was defined as systolic blood pressure (SBP) of 120–139 mmHg and/or diastolic blood pressure (DBP) of 80–89 mmHg. Results Overall, 1440 new cases of prehypertension were identified resulting in an incidence rate of 593/10000 person-years; the corresponding values for women and men were 489/10000 and 764/10000person-years, respectively. There were significant interactions between gender with age, DBP, waist-to-hip-ratio (WHpR) and estimated glomerular filtration rate (eGFR) (all P-values

  • distribution of ideal cardiovascular health in a community based cohort of Middle East Population
    Annals of Saudi Medicine, 2014
    Co-Authors: Mariam Maleki Moghaddam, Fereidoun Azizi, Reza Mohebi, Firoozeh Hosseini, Mojtaba Lotfaliany, Navid Saadat, Farzad Hadaegh
    Abstract:

    BACKGROUND AND OBJECTIVES: To improve cardiovascular (CV) health of American Population, the American Heart Association (AHA) developed definitions of ideal, intermediate, and poor CV health based ...

  • does an electrocardiogram add predictive value to the rose angina questionnaire for future coronary heart disease 10 year follow up in a Middle East Population
    Journal of Epidemiology and Community Health, 2012
    Co-Authors: Davood Khalili, Farzad Hadaegh, Nooshin Fahimfar, Farhad Sheikholeslami, Gita Shafiee, Arash Ghanbarian, Fereidoun Azizi
    Abstract:

    Background To evaluate the power of abnormal resting ECG versus Rose Questionnaire angina and its additive value in predicting 10-year coronary heart disease (CHD) risk in an Iranian urban Population with high prevalence of CHD. Methods There were 5101 subjects ≥30 years (2900 women), free of CHD at baseline; they were categorised in to four groups according to their Rose Angina and ECG status for ischaemia as Rose−/ECG−, Rose+/ECG−, Rose−/ECG+ and Rose+/ECG+. HR of CHD was estimated using Cox regression analysis, given Rose−/ECG− as the reference. The authors used Akaike information criterion, C-index and integrated discrimination improvement indices to evaluate the prognostic value of ECG when would be added to Rose Questionnaire. Results During follow-up, 387 CHD events (169 women) were observed. Multivariate analysis showed a HR of 2.59 (95% CI 1.71 to 3.91) and 2.26 (1.48 to 3.44) for Rose+/ECG− group in men and women, respectively. These figures for Rose−/ECG+ were 1.36 (0.90 to 2.05) in men and 2.09 (1.40 to 3.12) in women. There was no any interaction between Rose Questionnaire and gender to predict incident CHD, in age-adjusted analysis. Akaike information criterion, C-index and relative integrated discrimination improvement did not show any difference between models including Rose alone and Rose plus ECG to predict CHD events especially in men. Conclusions Rose Questionnaire as a simple screening tool is equally important to predict incident CHD in both genders. Adding abnormal ECG to angina did not culminate in higher risk for future CHD events.

  • Incidence of chronic kidney disease and its risk factors, results of over 10 year follow up in an Iranian cohort.
    PLOS ONE, 2012
    Co-Authors: Maryam Tohidi, Davood Khalili, Fereidoun Azizi, Reza Mohebi, Mitra Hasheminia, Farhad Hosseinpanah, Babak Yazdani, Amir Ahmad Nasiri, Farzad Hadaegh
    Abstract:

    To examine, the predictors of incident chronic kidney disease (CKD) in a community-based cohort of Middle East Population, during a mean follow-up of 9.9 years. In a sample of 3313 non-CKD Iranian adults ≥20 years the estimated glomerular filtration rate (eGFR) was calculated at baseline and at three year intervals during three consecutive phases. The eGFR 2% of individuals develops CKD each year. Our findings confirmed that sex- specific risk predictors should be considered in primary prevention for incident CKD.

  • adolescent lipoprotein classifications according to national health and nutrition examination survey nhanes vs national cholesterol education program ncep for predicting abnormal lipid levels in adulthood in a Middle East Population
    Lipids in Health and Disease, 2012
    Co-Authors: Masumeh Hatami, Davood Khalili, Fereidoun Azizi, Reza Mohebi, Maryam Tohidi, Farzad Hadaegh
    Abstract:

    Background: To compare the predictive ability of adolescent lipoprotein classification using the National Examination Survey (NHANES) cut points and those of the National Cholesterol Education Program (NCEP) for predicting abnormal levels in adulthood. Method: From 1032 adolescents, aged 14–19 years, participants of the Tehran Lipid and Glucose Study, all lipid measures were determined at baseline and again after 6 years. Multivariable Odds Ratios (ORs) were calculated for borderline and high categories of lipids to predict dyslipidemia in adulthood, considering the normal level as a reference. Area under the receiving characteristics curve (AUC) was used to assess the predictive ability of each adolescent lipid classification. Result: Applying the NCEP classification, the prevalences of high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides and low high density lipoprotein cholesterol (HDL-C) in males were 12.1%, 12.9%, 26.1% and 34.2% respectively; in females the corresponding prevalences were 15.4%, 17.9%, 21.4% and 25.0%, respectively. Using NHANES cut points, the prevalence of high TC, LDL-C and triglycerides were lower, than those defined by NCEP; the ORs of high categories of lipids (defined by NHANES) were higher than ORs based on the NECP classification, except for HDL-C. For all lipid measures, both classifications had similar predictive abilities, except for TC/HDL-C, which had higher predictive power applying the NHANES classification rather than the NCEP one (AUC 71% vs. 68%, respectively). Conclusion: No differences were found between NCEP and NHANES classifications for prediction of adult dyslipidemia, except for TC/HDL-C. Because of their simple application, NCEP cut points can be used in clinical settings.

Davood Khalili - One of the best experts on this subject based on the ideXlab platform.

  • Prehypertension Tsunami: A Decade Follow-Up of an Iranian Adult Population
    PLOS ONE, 2015
    Co-Authors: Farzad Hadaegh, Davood Khalili, Mitra Hasheminia, Hengameh Abdi, Mohammadreza Bozorgmanesh, Banafsheh Arshi, Fereidoun Azizi
    Abstract:

    Objective Prehypertension is associated with cardiovascular disease (CVD). There is no study to examine the incidence and risk factors of prehypertension in a sex stratified setting. The aim of this study was to examine the effect modification of sex for different risk factors which predicts the progression from normotension to prehypertension in a Middle East Population-based cohort, during a median follow-up of 9.2 years. Methods A multivariate Cox analysis was performed among 1466 and 2131 Iranian men and women, respectively, who were free of prehypertension, hypertension, CVD and diabetes at baseline and free of incident hypertension without preceding prehypertension at follow-up. Incident prehypertension at follow-up was defined as systolic blood pressure (SBP) of 120–139 mmHg and/or diastolic blood pressure (DBP) of 80–89 mmHg. Results Overall, 1440 new cases of prehypertension were identified resulting in an incidence rate of 593/10000 person-years; the corresponding values for women and men were 489/10000 and 764/10000person-years, respectively. There were significant interactions between gender with age, DBP, waist-to-hip-ratio (WHpR) and estimated glomerular filtration rate (eGFR) (all P-values

  • does an electrocardiogram add predictive value to the rose angina questionnaire for future coronary heart disease 10 year follow up in a Middle East Population
    Journal of Epidemiology and Community Health, 2012
    Co-Authors: Davood Khalili, Farzad Hadaegh, Nooshin Fahimfar, Farhad Sheikholeslami, Gita Shafiee, Arash Ghanbarian, Fereidoun Azizi
    Abstract:

    Background To evaluate the power of abnormal resting ECG versus Rose Questionnaire angina and its additive value in predicting 10-year coronary heart disease (CHD) risk in an Iranian urban Population with high prevalence of CHD. Methods There were 5101 subjects ≥30 years (2900 women), free of CHD at baseline; they were categorised in to four groups according to their Rose Angina and ECG status for ischaemia as Rose−/ECG−, Rose+/ECG−, Rose−/ECG+ and Rose+/ECG+. HR of CHD was estimated using Cox regression analysis, given Rose−/ECG− as the reference. The authors used Akaike information criterion, C-index and integrated discrimination improvement indices to evaluate the prognostic value of ECG when would be added to Rose Questionnaire. Results During follow-up, 387 CHD events (169 women) were observed. Multivariate analysis showed a HR of 2.59 (95% CI 1.71 to 3.91) and 2.26 (1.48 to 3.44) for Rose+/ECG− group in men and women, respectively. These figures for Rose−/ECG+ were 1.36 (0.90 to 2.05) in men and 2.09 (1.40 to 3.12) in women. There was no any interaction between Rose Questionnaire and gender to predict incident CHD, in age-adjusted analysis. Akaike information criterion, C-index and relative integrated discrimination improvement did not show any difference between models including Rose alone and Rose plus ECG to predict CHD events especially in men. Conclusions Rose Questionnaire as a simple screening tool is equally important to predict incident CHD in both genders. Adding abnormal ECG to angina did not culminate in higher risk for future CHD events.

  • Incidence of chronic kidney disease and its risk factors, results of over 10 year follow up in an Iranian cohort.
    PLOS ONE, 2012
    Co-Authors: Maryam Tohidi, Davood Khalili, Fereidoun Azizi, Reza Mohebi, Mitra Hasheminia, Farhad Hosseinpanah, Babak Yazdani, Amir Ahmad Nasiri, Farzad Hadaegh
    Abstract:

    To examine, the predictors of incident chronic kidney disease (CKD) in a community-based cohort of Middle East Population, during a mean follow-up of 9.9 years. In a sample of 3313 non-CKD Iranian adults ≥20 years the estimated glomerular filtration rate (eGFR) was calculated at baseline and at three year intervals during three consecutive phases. The eGFR 2% of individuals develops CKD each year. Our findings confirmed that sex- specific risk predictors should be considered in primary prevention for incident CKD.

  • adolescent lipoprotein classifications according to national health and nutrition examination survey nhanes vs national cholesterol education program ncep for predicting abnormal lipid levels in adulthood in a Middle East Population
    Lipids in Health and Disease, 2012
    Co-Authors: Masumeh Hatami, Davood Khalili, Fereidoun Azizi, Reza Mohebi, Maryam Tohidi, Farzad Hadaegh
    Abstract:

    Background: To compare the predictive ability of adolescent lipoprotein classification using the National Examination Survey (NHANES) cut points and those of the National Cholesterol Education Program (NCEP) for predicting abnormal levels in adulthood. Method: From 1032 adolescents, aged 14–19 years, participants of the Tehran Lipid and Glucose Study, all lipid measures were determined at baseline and again after 6 years. Multivariable Odds Ratios (ORs) were calculated for borderline and high categories of lipids to predict dyslipidemia in adulthood, considering the normal level as a reference. Area under the receiving characteristics curve (AUC) was used to assess the predictive ability of each adolescent lipid classification. Result: Applying the NCEP classification, the prevalences of high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides and low high density lipoprotein cholesterol (HDL-C) in males were 12.1%, 12.9%, 26.1% and 34.2% respectively; in females the corresponding prevalences were 15.4%, 17.9%, 21.4% and 25.0%, respectively. Using NHANES cut points, the prevalence of high TC, LDL-C and triglycerides were lower, than those defined by NCEP; the ORs of high categories of lipids (defined by NHANES) were higher than ORs based on the NECP classification, except for HDL-C. For all lipid measures, both classifications had similar predictive abilities, except for TC/HDL-C, which had higher predictive power applying the NHANES classification rather than the NCEP one (AUC 71% vs. 68%, respectively). Conclusion: No differences were found between NCEP and NHANES classifications for prediction of adult dyslipidemia, except for TC/HDL-C. Because of their simple application, NCEP cut points can be used in clinical settings.

  • new and known type 2 diabetes as coronary heart disease equivalent results from 7 6 year follow up in a Middle East Population
    Cardiovascular Diabetology, 2010
    Co-Authors: Farzad Hadaegh, Nooshin Fahimfar, Davood Khalili, Farhad Sheikholeslami, Fereidoun Azizi
    Abstract:

    Background To investigate whether the known diabetes mellitus (KDM) or newly diagnosed diabetes mellitus (NDM) could be regarded as a coronary heart disease (CHD) risk equivalent among a relatively young Middle East Population with high prevalence of diabetes mellitus (DM).

Zainab Shather - One of the best experts on this subject based on the ideXlab platform.

  • prevalence of metabolic syndrome and prediction of diabetes using idf versus atpiii criteria in a Middle East Population
    Diabetes Research and Clinical Practice, 2012
    Co-Authors: Cother Hajat, Zainab Shather
    Abstract:

    Abstract This study investigates the prevalence and predictive value of metabolic syndrome in Abu Dhabi, using data from the Population-based, programme, ‘Weqaya'. The Weqaya screen included family history of cardiovascular disease (CVD), CVD risk factors, random blood glucose (RBG) and HbA1c. Those not previously diabetic but at high risk of diabetes (RBG≥11.1mmol/l or HbA1c≥6.1%) and randomly selected normal subjects were followed-up with fasting glucose, oral glucose tolerance test (OGTT), HbA1c and fasting triglycerides. In 760 subjects, 325 (42.8%) were male with a mean age of 41.9 years (SD 13.8). Using World Health Organisation (WHO) criteria, 149 (20.2%) were newly diagnosed diabetics. Using International Diabetes Foundation (IDF) and Adult Treatment Panel III (ATPIII) criteria, metabolic syndrome was present in 29.0% vs. 31.5% of non-diabetics, 63.4% vs. 64.2% with impaired glucose handling and 78.6% vs. 79.8% with new-onset diabetes using OGTT ( P P P P

Farhad Sheikholeslami - One of the best experts on this subject based on the ideXlab platform.

  • does an electrocardiogram add predictive value to the rose angina questionnaire for future coronary heart disease 10 year follow up in a Middle East Population
    Journal of Epidemiology and Community Health, 2012
    Co-Authors: Davood Khalili, Farzad Hadaegh, Nooshin Fahimfar, Farhad Sheikholeslami, Gita Shafiee, Arash Ghanbarian, Fereidoun Azizi
    Abstract:

    Background To evaluate the power of abnormal resting ECG versus Rose Questionnaire angina and its additive value in predicting 10-year coronary heart disease (CHD) risk in an Iranian urban Population with high prevalence of CHD. Methods There were 5101 subjects ≥30 years (2900 women), free of CHD at baseline; they were categorised in to four groups according to their Rose Angina and ECG status for ischaemia as Rose−/ECG−, Rose+/ECG−, Rose−/ECG+ and Rose+/ECG+. HR of CHD was estimated using Cox regression analysis, given Rose−/ECG− as the reference. The authors used Akaike information criterion, C-index and integrated discrimination improvement indices to evaluate the prognostic value of ECG when would be added to Rose Questionnaire. Results During follow-up, 387 CHD events (169 women) were observed. Multivariate analysis showed a HR of 2.59 (95% CI 1.71 to 3.91) and 2.26 (1.48 to 3.44) for Rose+/ECG− group in men and women, respectively. These figures for Rose−/ECG+ were 1.36 (0.90 to 2.05) in men and 2.09 (1.40 to 3.12) in women. There was no any interaction between Rose Questionnaire and gender to predict incident CHD, in age-adjusted analysis. Akaike information criterion, C-index and relative integrated discrimination improvement did not show any difference between models including Rose alone and Rose plus ECG to predict CHD events especially in men. Conclusions Rose Questionnaire as a simple screening tool is equally important to predict incident CHD in both genders. Adding abnormal ECG to angina did not culminate in higher risk for future CHD events.

  • new and known type 2 diabetes as coronary heart disease equivalent results from 7 6 year follow up in a Middle East Population
    Cardiovascular Diabetology, 2010
    Co-Authors: Farzad Hadaegh, Nooshin Fahimfar, Davood Khalili, Farhad Sheikholeslami, Fereidoun Azizi
    Abstract:

    Background To investigate whether the known diabetes mellitus (KDM) or newly diagnosed diabetes mellitus (NDM) could be regarded as a coronary heart disease (CHD) risk equivalent among a relatively young Middle East Population with high prevalence of diabetes mellitus (DM).