The Experts below are selected from a list of 2289 Experts worldwide ranked by ideXlab platform

Fitria Rahmitasari - One of the best experts on this subject based on the ideXlab platform.

  • PEMBERIAN GEL SPIRULINA (Blue Green Algae) TERHADAP JUMLAH SEL FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI MARMUT (Cavia Cobaya)
    2012
    Co-Authors: Fitria Rahmitasari
    Abstract:

    Background: Wound healing treatment after tooth extraction should be an important consideration due to Mouth Discomfort and pain. Spirulina (blue green algae) consists of C-phycocyanin, β–Carotenoids, vitamin E, zinc, and some other trace elements and natural phytochemical which are belived to act as antioxidant and take part in wound healing process. Purpose: To differ the effect of Spirulina gel towards Cavia cobaya fibroblast cell number over wound healing process after tooth extraction. Methods: Have their left incisive tooth extracted, research animals are then divided into 4 groups based on concentrations: 0%, 3%, 6%, and 12%. All samples are executed on the 5th day of application to perform histopathological evaluation as well as to count fibroblast cell among groups. Result: The research has proven the relation between the increased growth of fibroblast cell and Spirulina gel application. The higher the doses, the more cell growth. Hence, hhere has been significant different (p

  • The effect of spirulina gel on fibroblast cell number after wound healing
    Dental Journal: Majalah Kedokteran Gigi, 2011
    Co-Authors: Fitria Rahmitasari, Wisnu Setyari J, Ester Arijani Rachmat
    Abstract:

    Background: Wound healing treatment after tooth extraction should be an important consideration due to Mouth Discomfort and pain. Spirulina (blue green algae) consists of C-phycocyanin, b –carotenoids, vitamin E, zinc, some other trace elements and natural phytochemical which are believed to act as antioxidant and takes part in wound healing process. Purpose: The purpose of this study was to examine the effect of spirulina gel on fibroblast cell number after wound healing process. Methods: Twenty eight males guinea pig are devided into four group, 7 guinea pig each. They are control group and treatment group which is given 0%, 3%, 6%, and 12% spirulina gel. After tooth extraction, histopathological evaluation was done to count fibroblast cell. The data was analyzed by One-Way ANOVA and Tukey HSD. Results: The research has proven the relation between the increased growth of fibroblast cell and spirulina gel application. The higher the doses, the more cell growth. Hence, there has been significant different (p < 0.05) among groups. Conclusion: Spirulina gel increases the number of fibroblast in wound after tooth extraction and 12% spirulina gel has the most potential ability. Latar Belakang: Proses penyembuhan luka pasca pencabutan gigi merupakan salah satu hal yang penting karena akan menimbulkan rasa nyeri dan tidak nyaman dalam rongga mulut. Spirulina (Blue green Algae) mengandung C-phycocyanin, b -carotenoids, vitamin E, seng, beberapa trace elemen lainnya, dan phytochemical alami yang terbukti dapat berperan sebagai antioksidan dalam proses penyembuhan luka. Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui efek pemberian gel spirulina terhadap jumlah sel fibroblas pada proses penyembuhan luka pasca pencabutan gigi. Metode: Dua puluh delapan ekor guinea pig jantan dibagi dalam 7 kelompok, masing-masing terdiri dari 4 ekor. Kelompok tersebut adalah kelompok kontrol dan kelompok perlakuan yang diberikan gel spirulina dengan konsentrasi 0%, 3%, 6%, dan 12%. Setelah pencabutan gigi, dilakukan penghitungan sel fibroblas dengan metode histopatologi. Hasil: Penelitian ini menunjukkan adanya hubungan antara pemberian gel spirulina terhadap peningkatan jumlah sel fibroblas. Semakin tinggi dosis gel spirulina akan semakin meningkatkan jumlah sel fibroblas pula. Didapatkan perbedaan yang signifikan antar kelompok (p < 0,05). Kesimpulan: Gel spirulina meningkatkan jumlah sel fibroblas pada luka bekas pencabutan dan gel spirulina dengan konsentrasi 12% mempunyai kemampuan yang paling potensial.

Adi Kristanto Tandjaja - One of the best experts on this subject based on the ideXlab platform.

  • PENINGKATAN JUMLAH SEL FIBROBLAS AKIBAT PEMBERIAN EKSTRAK BIJI SEMANGKA (Citrullus lanatus) PADA PENYEMBUHAN LUKA
    2013
    Co-Authors: Adi Kristanto Tandjaja
    Abstract:

    Background: Wound healing treatment is an important thing because it can cause pain and Mouth Discomfort. Watermelon seed contain arginine and glutamate acid. Both are conditionally essential amino acid that is needed in wound healing, especially in proliferation fase. Purpose: The aim of this study is to examine the effect of watermelon seed extract on fibroblast cell number in wound healing process. Material and methods : 28 male cavia cobaya are divided into 4 groups: the first group, KK-I (on the third day HPA evaluation is taken , it is not given any treatment), KP1 ( is given watermelon seed extract orally for three days and on the third day HPA evaluation is taken, KK2 (on the 7th day, HPA evaluation is taken, it is not given watermelon seed extract), KP2 (on the 7th day, HPA evaluation is taken, and watermelon seed extract is given) 1 cm wound is made on dorsal cavia cobaya. Result: There is significant difference of the amount of fibroblast cell in wound healing in the group with and without the consumption of watermelon seed extract. Conclusion: The consumption of watermelon seed extract with 100 % consentration can increase the amount of fibroblas in wound healing.

Deepa Guruanthan - One of the best experts on this subject based on the ideXlab platform.

  • Postoperative Discomfort of Children Following Dental Treatment under General Anaesthesia
    2016
    Co-Authors: Sudha Dharshini, Deepa Guruanthan
    Abstract:

    Postoperative Discomfort of Children Following Dental Treatment under General Anaesthesia Aim: The aim of this study is to evaluate the post-operative Discomfort in children undergoing dental treatment under General anaesthesia. Background: Post-operative Discomfort in children is an undesirable outcome of paediatric anaesthesia. The purpose of this study to investigate post-operative Discomfort associated with dental care under General anaesthesia. Materials and Methods: This study involves healthy patients who were scheduled for General anaesthesia who required extensive dental treatment due severe caries and behavioural management problems .The study is involves a questionnaire which consist of questions related to postoperative problems experienced by the patients. Complications were assessed through telephone calls to the patient’s mother /guardian, which was made on the same day.Results: The incidence of postoperative problems was found in 45 out of 50 children. Some of the patients have more than one reported problem. The most common experienced postoperative symptom after Dental Rehabilitation under administration of general anaesthesia was changes in face (60%) and (48% ) had fever, Mouth Discomfort (40%) ,problems while eating (34%)and throat Discomfort (14%).The least common Discomfort was diarrhoea (8%) and constipation (2%). Conclusion: Changes in the face such as swelling was the most common observation seen in children treated under general Anaesthesia.

Ester Arijani Rachmat - One of the best experts on this subject based on the ideXlab platform.

  • The effect of spirulina gel on fibroblast cell number after wound healing
    Dental Journal: Majalah Kedokteran Gigi, 2011
    Co-Authors: Fitria Rahmitasari, Wisnu Setyari J, Ester Arijani Rachmat
    Abstract:

    Background: Wound healing treatment after tooth extraction should be an important consideration due to Mouth Discomfort and pain. Spirulina (blue green algae) consists of C-phycocyanin, b –carotenoids, vitamin E, zinc, some other trace elements and natural phytochemical which are believed to act as antioxidant and takes part in wound healing process. Purpose: The purpose of this study was to examine the effect of spirulina gel on fibroblast cell number after wound healing process. Methods: Twenty eight males guinea pig are devided into four group, 7 guinea pig each. They are control group and treatment group which is given 0%, 3%, 6%, and 12% spirulina gel. After tooth extraction, histopathological evaluation was done to count fibroblast cell. The data was analyzed by One-Way ANOVA and Tukey HSD. Results: The research has proven the relation between the increased growth of fibroblast cell and spirulina gel application. The higher the doses, the more cell growth. Hence, there has been significant different (p < 0.05) among groups. Conclusion: Spirulina gel increases the number of fibroblast in wound after tooth extraction and 12% spirulina gel has the most potential ability. Latar Belakang: Proses penyembuhan luka pasca pencabutan gigi merupakan salah satu hal yang penting karena akan menimbulkan rasa nyeri dan tidak nyaman dalam rongga mulut. Spirulina (Blue green Algae) mengandung C-phycocyanin, b -carotenoids, vitamin E, seng, beberapa trace elemen lainnya, dan phytochemical alami yang terbukti dapat berperan sebagai antioksidan dalam proses penyembuhan luka. Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui efek pemberian gel spirulina terhadap jumlah sel fibroblas pada proses penyembuhan luka pasca pencabutan gigi. Metode: Dua puluh delapan ekor guinea pig jantan dibagi dalam 7 kelompok, masing-masing terdiri dari 4 ekor. Kelompok tersebut adalah kelompok kontrol dan kelompok perlakuan yang diberikan gel spirulina dengan konsentrasi 0%, 3%, 6%, dan 12%. Setelah pencabutan gigi, dilakukan penghitungan sel fibroblas dengan metode histopatologi. Hasil: Penelitian ini menunjukkan adanya hubungan antara pemberian gel spirulina terhadap peningkatan jumlah sel fibroblas. Semakin tinggi dosis gel spirulina akan semakin meningkatkan jumlah sel fibroblas pula. Didapatkan perbedaan yang signifikan antar kelompok (p < 0,05). Kesimpulan: Gel spirulina meningkatkan jumlah sel fibroblas pada luka bekas pencabutan dan gel spirulina dengan konsentrasi 12% mempunyai kemampuan yang paling potensial.

Raditya Arrdhi Sradhana - One of the best experts on this subject based on the ideXlab platform.

  • PENURUNAN EKSPRESI TNF-α DAN PENINGKATANJUMLAH PEMBULUH DARAH PADA PROSESPENYEMBUHAN LUKA PENCABUTAN GIGI SETELAHPEMBERIAN EKSTRAK GARDENIA JASMINOIDES(Penelitian Eksperimental dengan menggunakan binatang cobaTikus Wistar)
    2015
    Co-Authors: Raditya Arrdhi Sradhana
    Abstract:

    Background : Wound healing after tooth extraction treatment should be an important consideration because the Mouth Discomfort and pain. Gardenia jasminoides composed of geniposide and chlorogenic acid acts as an anti-inflammatory in the wound healing process. Purpose : To prove that the extract of Gardenia jasminoides 3% potentially decrease wound healing. Methods : This experimental research design with post test only control group identified the effect of topical application of 3% of Gardenia jasminoides leaves water extract on wound healing by checking the appearance hitopathological of TNF alpha and blood vessels. Tooth extraction performed on insisive Mandibule of 28 rats were divided into control and test groups where the test group received a topical application of 3% of Gardenia jasminoides water extract of leaves. Wound examined on days 3 and 5 using a light microscope. Result : The results showed the tendency of better wound healing in the test group for all parameters based on data on day 3 and 5. One Way ANOVA l Independent t test (p 0.05). The results are statistically significant. Conclusion : topical application of 3% of Gardenia jasminoides leaves water extracts effectively decreased the expression of TNF alpha and increase the number of blood vessels that will help the wound healing process.