The Experts below are selected from a list of 18420 Experts worldwide ranked by ideXlab platform
Masayuki Azuma - One of the best experts on this subject based on the ideXlab platform.
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management of Tooth Extraction in a patient with elane gene mutation induced cyclic neutropenia a case report
2019Co-Authors: Keiko Aota, Koichi Kani, Tomoko Yamanoi, Yukihiro Momota, Masami Ninomiya, Hiromichi Yumoto, Masayuki AzumaAbstract:AbstractIntroduction:Cyclic neutropenia (CyN) is a rare hematological disease, and patients with CyN often experience an early onset of severe periodontitis and are forced to undergo Tooth Extraction. Here, we report a case of a patient with CyN who showed different periodicity and oscillations of n
Reinhard Gruber - One of the best experts on this subject based on the ideXlab platform.
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caspase inhibitor attenuates the shape changes in the alveolar ridge following Tooth Extraction a pilot study in rats
2021Co-Authors: Uwe Yacine Schwarze, Franz Josef Strauss, Reinhard GruberAbstract:OBJECTIVE The aim of the study was to determine whether the inhibition of apoptosis via pan-caspase inhibitors can attenuate the changes in the alveolar ridge upon Tooth Extraction. BACKGROUND Cells undergoing apoptosis might play a central role in the onset of alveolar bone resorption and the ensuing bone atrophy following Tooth Extraction. Caspases are proteases that regulate apoptotic cell death. It is, therefore, reasonable to hypothesize that blocking apoptosis with pan-caspase inhibitors attenuates the changes in the alveolar ridge following Tooth Extraction. METHODS In 16 inbred rats, the mandibular first (M1) and second (M2) molars of one side were extracted. Following random allocation, the rats received either a cell-permeable pan-caspase inhibitor or diluent. After a healing period of 10 days, changes in shape and height of the alveolar ridge were examined using geometric morphometrics and linear measurements based on micro-computed tomography. RESULTS Geometric morphometric analysis revealed that the pan-caspase inhibitor prevented major shape changes of the alveolar ridge following M1 Tooth Extraction (P < .05). Furthermore, linear measurements confirmed that the pan-caspase inhibitor significantly prevented the atrophy of the alveolar ridge height following M1 Tooth Extraction compared to the diluent controls (-0.53 mm vs -0.24 mm; P = .012). M2 Tooth Extraction caused no shape changes of the alveolar ridge, and thus, the pan-caspase inhibitor group did not differ from the control group (-0.14 mm vs -0.05 mm; P = .931). CONCLUSIONS These findings suggest that the inhibition of apoptosis may attenuate shape changes of the alveolar ridge following M1 Tooth Extraction in rodents.
Keiko Aota - One of the best experts on this subject based on the ideXlab platform.
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management of Tooth Extraction in a patient with elane gene mutation induced cyclic neutropenia a case report
2019Co-Authors: Keiko Aota, Koichi Kani, Tomoko Yamanoi, Yukihiro Momota, Masami Ninomiya, Hiromichi Yumoto, Masayuki AzumaAbstract:AbstractIntroduction:Cyclic neutropenia (CyN) is a rare hematological disease, and patients with CyN often experience an early onset of severe periodontitis and are forced to undergo Tooth Extraction. Here, we report a case of a patient with CyN who showed different periodicity and oscillations of n
Sangheng Kok - One of the best experts on this subject based on the ideXlab platform.
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post Tooth Extraction sepsis without locoregional infection a population based study in taiwan
2009Co-Authors: Jangjaer Lee, Haohueng Chang, Shihjung Cheng, Liangjiunn Hahn, T P Kao, C H Liu, Shijung Cheng, Jiianghuei Jeng, Sangheng KokAbstract:Objective To investigate the incidence and risk factors of post-Tooth Extraction sepsis in patients without locoregional infection. Subjects and methods We assessed all claim records of the Taiwanese National Health Insurance program in 2005. Admissions for patients aged > or =16 years containing a discharge diagnosis of sepsis, and who received Tooth Extraction within 14 days before the admission were identified. Patient charts were reviewed to confirm the diagnosis of sepsis and rule out other infection sources. The relationship between postExtraction sepsis (PES) and clinical parameters was analyzed. Results Thirty-three of the 2 223 971 Extraction cases met the criteria of PES, an incidence of 1.48 per 100 000, and seven patients (21.2%) died of the disease. Aging significantly increased the risk of PES (P Conclusion Tooth Extraction is associated with a low but significant risk of postoperative sepsis, especially in the elderly and patients with underlying diseases.
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effectiveness of an educational program in reducing the incidence of wrong site Tooth Extraction
2004Co-Authors: Haohueng Chang, Jangjaer Lee, Shihjung Cheng, Puojen Yang, L J Hahn, Yingshiung Kuo, Wanhong Lan, Sangheng KokAbstract:Abstract Objectives The aim of the study was to investigate the effectiveness of an educational program on the reduction of the incidence of wrong-site Tooth Extraction at the outpatient department of a university hospital in Taiwan. Study design Data collected from cases of wrong-site Tooth Extraction during 1996 to 1998 were used to develop a specific educational intervention that was implemented from 1999 to 2001. The annual incidence of erroneous Extraction was compared between the preintervention and intervention periods. The factors contributing to wrong Tooth Extraction were also analyzed. Results The annual incidence rates of erroneous Extraction from 1996 to 1998 were 0.026%, 0.025%, and 0.046%, respectively. During the intervention period from 1999 to 2001, wrong-site Tooth Extraction did not occur at the department. There was a significant difference in the incidence of erroneous Extraction between the preintervention and intervention periods (P Conclusions Our results suggest the effectiveness of an educational program comprising case-based materials, information feedback, and clinical guidelines in reducing the incidence of wrong-site Tooth Extraction.
Nele Van Assche - One of the best experts on this subject based on the ideXlab platform.
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microbial changes after full mouth Tooth Extraction followed by 2 stage implant placement
2011Co-Authors: Marc Quirynen, Nele Van AsscheAbstract:Quirynen M, Van Assche N. Microbial changes after full-mouth Tooth Extraction, followed by 2-stage implant placement. J Clin Peridontol 2011; doi: 10.1111/j.1600-051X.2011.01728.x. Abstract: Background: Recent studies showed that qPCR could detect bacteria related to periodontitis and peri-implantitis in a low concentration after full-mouth Tooth Extraction. This study monitored the microbiota from Tooth Extraction, over 9 months of full edentulism, up to 1 year after abutment connection. Material and methods: Ten patients with severe periodontitis were recruited. Six months after Tooth Extraction, implants were inserted. Three to 6 months later, they were connected to abutments. Plaque samples were collected from the tongue dorsum, saliva, and subgingival area (teeth/implants) before Extraction up to 1 year after abutment connection, and analysed via culture, qPCR, and checkerboard technology. Results: A reduction in the total amount of aerobic and anaerobic CFU/ml was observed. The concentration of Porphyromonas gingivalis and Tannerella forsythia (qPCR and checkerboard) in the saliva and, to a lower extent, on the tongue dorsum reduced. For Prevotella intermedia, changes were negligible and no changes could be detected for Aggregatibacter actinomycetemcomitans. The pristine subgingival niches were quickly colonized by key pathogens. Their final concentration remained low, while the detection frequencies remained very high over time. Conclusion: Complete edentulation results in a significant reduction of bacteria related to periodontitis and peri-implantitis, with the exception of A. actinomycetemcomitans, which might indicate that key pathogens can survive without pockets.
