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Joost Dekker - One of the best experts on this subject based on the ideXlab platform.
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falls associated with Muscle Strength in patients with knee osteoarthritis and self reported knee instability
The Journal of Rheumatology, 2015Co-Authors: Arjan De Zwart, M Van Der Esch, Willem F Lems, Joost Dekker, Marike Van Der Leeden, L D Roorda, Mirjam Pijnappels, Marco J M Hoozemans, Jaap H Van DieenAbstract:Objective. We aimed to evaluate the associations between knee Muscle Strength (MS) and falls, controlling for knee joint proprioception, varus-valgus knee joint laxity, and knee pain, among patients with knee osteoarthritis (OA) reporting knee instability. Methods. A sample of 301 subjects (203 women, 98 men, 35–82 yrs) with established knee OA and self-reported knee instability was studied. The occurrence of at least 1 fall in the previous 3 months was assessed by questionnaire. Maximum knee extension and flexion Strength were measured isokinetically. Additionally, proprioception, varus-valgus laxity, and pain were assessed. Student t tests were used to assess differences between subgroups. The association of Muscle Strength and falls was calculated using univariate and multivariate logistic regression analysis. Results. Over 10% of the subjects (31 out of 301) reported a fall in the previous 3 months. High knee extension Muscle Strength (crude OR 0.3, 95% CI 0.1–0.8, p = 0.022) and high knee flexion Muscle Strength (crude OR 0.2, 95% CI 0.0–1.0, p = 0.048) were associated with a lower risk of falls. Proprioception and laxity did not confound this relationship. After adjusting for pain, extensor Strength had an adjusted OR of 0.5 (95% CI 0.2–1.4, p = 0.212) for falls and flexor Strength had an adjusted OR of 0.4 (95% CI 0.1–2.3, p = 0.312). Conclusion. High knee extension and flexion Muscle Strength decreased the risk of falls in patients with knee OA and self-reported knee instability. After considering the effect of pain, there was insufficient statistical power to detect an association between Muscle Strength and falls, which might be because of the low number of subjects who fell (n = 31).
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association of serum c reactive protein and erythrocyte sedimentation rate with Muscle Strength in patients with knee osteoarthritis
Rheumatology, 2013Co-Authors: Diana C Sanchezramirez, M Van Der Esch, Joost Dekker, Marike Van Der Leeden, Martijn Gerritsen, L D Roorda, Jaap H Van Dieen, Sabine Verschueren, Willem F LemsAbstract:Objective. To examine the association of serum CRP and ESR with Muscle Strength in patients with knee OA. Methods. Cross-sectional data from 285 patients with knee OA from the Amsterdam Osteoarthritis (AMS-OA) cohort were analysed. CRP (mg/l) and ESR (mm/l) were measured in serum from patients’ blood samples and the values were dichotomized for the analyses. Strength of quadriceps and hamstring Muscles was assessed using an isokinetic dynamometer. Univariable and multivariable linear regression analyses were used to assess the association of CRP and ESR with Muscle Strength, adjusting for relevant confounders. Results. Elevated levels of serum CRP (� = � 0.10; P = 0.04) and ESR (� = � 0.12; P = 0.02) were associated with lower Muscle Strength after adjustment for age, sex, comorbidities and NSAID use. The associations were no longer significant when BMI was incorporated in the adjusted model. Conclusion. Inflammation might influence Muscle Strength in patients with knee OA. Moreover, the link between inflammation and obesity might explain the effect that BMI has in the associations between inflammatory markers (i.e. CRP and ESR) and Muscle Strength.
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association of lower Muscle Strength with self reported knee instability in osteoarthritis of the knee results from the amsterdam osteoarthritis cohort
Arthritis Care and Research, 2012Co-Authors: J Knoop, M Van Der Esch, Willem F Lems, Joost Dekker, Marike Van Der Leeden, R E Voorneman, Martijn Gerritsen, Carina A Thorstensson, L D Roorda, Martijn SteultjensAbstract:Objective To determine whether Muscle Strength, proprioceptive accuracy, and laxity are associated with self-reported knee instability in a large cohort of knee osteoarthritis (OA) patients, and to investigate whether Muscle Strength may compensate for impairment in proprioceptive accuracy or laxity, in order to maintain knee stability. Methods. Data from 283 knee OA patients from the Amsterdam Osteoarthritis cohort were used. Univariable and multivariable logistic regression analyses were performed to assess the association between Muscle Strength, proprioceptive accuracy (motion sense), frontal plane varus-valgus laxity, and self-reported knee instability. Additionally, effect modification between Muscle Strength and proprioceptive accuracy and between Muscle Strength and laxity was determined. Results. Self-reported knee instability was present in 67% of the knee OA patients and mainly occurred during walking. Lower Muscle Strength was significantly associated with the presence of self-reported knee instability, even after adjusting for relevant confounding. Impaired proprioceptive accuracy and high laxity were not associated with self-reported knee instability. No effect modification between Muscle Strength and proprioceptive accuracy or laxity was found. Conclusion. Lower Muscle Strength is strongly associated with self-reported knee instability in knee OA patients, while impairments in proprioceptive accuracy and laxity are not. A compensatory role of Muscle Strength for impaired proprioceptive accuracy or high laxity, in order to stabilize the knee, could not be demonstrated. (Less)
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joint proprioception Muscle Strength and functional ability in patients with osteoarthritis of the knee
Arthritis & Rheumatism, 2007Co-Authors: M Van Der Esch, Martijn P. M. Steultjens, Dirk L Knol, Jaap Harlaar, Willem F Lems, Joost DekkerAbstract:Objective To test the hypotheses that poor knee joint proprioception is related to limitations in functional ability, and poor proprioception aggravates the impact of Muscle weakness on limitations in functional ability in osteoarthritis (OA) of the knee. Methods Sixty-three patients with symptomatic OA of the knee were tested. Proprioceptive acuity was assessed by establishing the joint motion detection threshold (JMDT) in the anteroposterior direction. Muscle Strength was measured using a computer-driven isokinetic dynamometer. Functional ability was assessed by the 100-meter walking test, the Get Up and Go (GUG) test, and the Western Ontario and McMaster Universities Osteoarthritis Index physical function (WOMAC-PF) questionnaire. Correlation analyses were performed to assess the relationship between proprioception, Muscle Strength, and functional ability. Regression analyses were performed to assess the impact of proprioception on the relationship between Muscle Strength and functional ability. Results Poor proprioception (high JMDT) was related to more limitation in functional ability (walking time r = 0.30, P < 0.05; GUG time r = 0.30, P < 0.05; WOMAC-PF r = 0.26, P <0.05). In regression analyses, the interaction between proprioception and Muscle Strength was significantly related to functional ability (walking time, P < 0.001 and GUG time, P < 0.001) but not to WOMAC-PF score (P = 0.625). In patients with poor proprioception, reduction of Muscle Strength was associated with more severe deterioration of functional ability than in patients with accurate proprioception. Conclusion Patients with poor proprioception show more limitation in functional ability, but this relationship is rather weak. In patients with poor proprioception, Muscle weakness has a stronger impact on limitations in functional ability than in patients with accurate proprioception.
Andrea B Maier - One of the best experts on this subject based on the ideXlab platform.
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lower cognitive function in older patients with lower Muscle Strength and Muscle mass
Dementia and Geriatric Cognitive Disorders, 2018Co-Authors: Romee Van Dam, Jeanine M Van Ancum, Sjors Verlaan, Kira Scheerman, Carel G M Meskers, Andrea B MaierAbstract:BACKGROUND: Low Muscle Strength and Muscle mass are associated with adverse outcomes in older hospitalized patients. The aim of this study was to assess the association between cognitive functioning and Muscle Strength and Muscle mass in hospitalized older patients. METHODS: This prospective inception cohort included 378 patients aged 70 years or older. At admission patients were assessed for cognitive functioning by use of the Six-Item Cognitive Impairment Test (6-CIT). Muscle Strength and Muscle mass were assessed using handheld dynamometry and segmental multifrequency bioelectrical impedance analysis, within 48 h after admission and on day 7, or earlier on the day of discharge. RESULTS: The data of 371 patients (mean age ± standard deviation 80.1 ± 6.4 years, 49.3% female) were available for analyses. The median (interquartile range) 6-CIT score was 4 (0-8) points. At admission, lower cognitive functioning was associated with lower Muscle Strength, lower skeletal Muscle mass (SMM), lower appendicular lean mass, and lower SMM index. Cognitive functioning was not associated with change in Muscle Strength and Muscle mass during hospitalization. CONCLUSION: This study further Strengthens evidence for an association between lower cognitive functioning and lower Muscle Strength and Muscle mass, but without a further decline during hospitalization.
Henning Bliddal - One of the best experts on this subject based on the ideXlab platform.
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experimental knee joint pain during Strength training and Muscle Strength gain in healthy subjects a randomized controlled trial
Arthritis Care and Research, 2012Co-Authors: T J Sorensen, Henning Bliddal, Henning Langberg, Paul W Hodges, Marius HenriksenAbstract:Objective Knee joint pain and reduced quadriceps Strength are cardinal symptoms in many knee pathologies. In people with painful knee pathologies, quadriceps exercise reduces pain, improves physical function, and increases Muscle Strength. A general assumption is that pain compromises Muscle function and thus may prevent effective rehabilitation. This study evaluated the effects of experimental knee joint pain during quadriceps Strength training on Muscle Strength gain in healthy individuals. Methods Twenty-seven healthy untrained volunteers participated in a randomized controlled trial of quadriceps Strengthening (3 times per week for 8 weeks). Participants were randomized to perform resistance training either during pain induced by injections of painful hypertonic saline (pain group, n = 13) or during a nonpainful control condition with injection of isotonic saline (control group, n = 14) into the infrapatellar fat pad. The primary outcome measure was change in maximal isokinetic Muscle Strength in knee extension/flexion (60, 120, and 180 degrees/second). Results The group who exercised with pain had a significantly larger improvement in isokinetic Muscle Strength at all angular velocities of knee extension compared to the control group. In knee flexion there were improvements in isokinetic Muscle Strength in both groups with no between-group differences. Conclusion Experimental knee joint pain improved the training-induced gain in Muscle Strength following 8 weeks of quadriceps training. It remains to be studied whether knee joint pain has a positive effect on Strength gain in patients with knee pathology.
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experimental knee pain reduces Muscle Strength
The Journal of Pain, 2011Co-Authors: Marius Henriksen, Sara Rosager, J Aaboe, Thomas Gravennielsen, Henning BliddalAbstract:Abstract Pain is the principal symptom in knee pathologies and reduced Muscle Strength is a common observation among knee patients. However, the relationship between knee joint pain and Muscle Strength remains to be clarified. This study aimed at investigating the changes in knee Muscle Strength following experimental knee pain in healthy volunteers, and if these changes were associated with the pain intensities. In a crossover study, 18 healthy subjects were tested on 2 different days. Using an isokinetic dynamometer, maximal Muscle Strength in knee extension and flexion was measured at angular velocities 0, 60, 120, and 180 degrees/second, before, during, and after experimental pain induced by injections of hypertonic saline into the infrapatellar fat pad. On a separate day, isotonic saline injections were used as control condition. The pain intensity was assessed on a 0- to 100-mm visual analogue scale. Knee pain reduced the Muscle Strength by 5 to 15% compared to the control conditions ( P Perspective This study showed that knee joint pain has a significant impact on Muscle function. The findings provide evidence of a direct inhibition of Muscle function by joint pain, implying that rehabilitative Strengthening exercises may be antagonized by joint pain.
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isokinetic and isometric Muscle Strength in a healthy population with special reference to age and gender
Acta Physiologica, 2009Co-Authors: Bente Danneskioldsamsoe, Else Marie Bartels, P M Bulow, Hans Lund, Anders Stockmarr, C C Holm, I Watjen, Merete Appleyard, Henning BliddalAbstract:Aim: Muscle Strength is an excellent indicator of general health when based on reliable measurements. Muscle Strength data for a healthy population are rare or non-existent. The aim of the present study was to measure a set of normal values for isometric and isokinetic Muscle Strength for all the major joint movements of the body and, from these data, to create a basis for comparison of the Muscle Strength of an individual with the expected value in a normal population. Methods: A randomly selected group, aged 20–80 years, from the Copenhagen City Heart Study were studied. The group was subgrouped according to age and gender. Isometric and isokinetic Muscle Strength was measured in each subject across the main joints in the body. A statistical model was developed that encompassed the three main Muscle groups: upper limbs, trunk and lower limbs. Results: Muscle Strength in healthy men decreases in a linear fashion from the age of 25 years down to between 54% and 89% at the age of 75 years, and seems not highly dependent on any other parameter than age. For women, the Muscle Strength is dependent on weight and is only related to age from around 40 years of age. The decrease in Muscle Strength from the age around 40 to 75 years is 48–92%. For most Muscle groups, men are 1.5–2 times stronger than women, with the oldest men having Strength similar to that observed among the youngest women. Conclusion: We developed a model to compare the isometric and isokinetic Muscle Strength of all the major joint movements of an individual with values for a healthy man or woman at any age in the range of 20–80 years. In all age groups, women have lower Muscle Strength than men. Men’s Muscle Strength declines with age, while women’s Muscle Strength declines from the age of 41 years.
M Van Der Esch - One of the best experts on this subject based on the ideXlab platform.
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falls associated with Muscle Strength in patients with knee osteoarthritis and self reported knee instability
The Journal of Rheumatology, 2015Co-Authors: Arjan De Zwart, M Van Der Esch, Willem F Lems, Joost Dekker, Marike Van Der Leeden, L D Roorda, Mirjam Pijnappels, Marco J M Hoozemans, Jaap H Van DieenAbstract:Objective. We aimed to evaluate the associations between knee Muscle Strength (MS) and falls, controlling for knee joint proprioception, varus-valgus knee joint laxity, and knee pain, among patients with knee osteoarthritis (OA) reporting knee instability. Methods. A sample of 301 subjects (203 women, 98 men, 35–82 yrs) with established knee OA and self-reported knee instability was studied. The occurrence of at least 1 fall in the previous 3 months was assessed by questionnaire. Maximum knee extension and flexion Strength were measured isokinetically. Additionally, proprioception, varus-valgus laxity, and pain were assessed. Student t tests were used to assess differences between subgroups. The association of Muscle Strength and falls was calculated using univariate and multivariate logistic regression analysis. Results. Over 10% of the subjects (31 out of 301) reported a fall in the previous 3 months. High knee extension Muscle Strength (crude OR 0.3, 95% CI 0.1–0.8, p = 0.022) and high knee flexion Muscle Strength (crude OR 0.2, 95% CI 0.0–1.0, p = 0.048) were associated with a lower risk of falls. Proprioception and laxity did not confound this relationship. After adjusting for pain, extensor Strength had an adjusted OR of 0.5 (95% CI 0.2–1.4, p = 0.212) for falls and flexor Strength had an adjusted OR of 0.4 (95% CI 0.1–2.3, p = 0.312). Conclusion. High knee extension and flexion Muscle Strength decreased the risk of falls in patients with knee OA and self-reported knee instability. After considering the effect of pain, there was insufficient statistical power to detect an association between Muscle Strength and falls, which might be because of the low number of subjects who fell (n = 31).
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association of serum c reactive protein and erythrocyte sedimentation rate with Muscle Strength in patients with knee osteoarthritis
Rheumatology, 2013Co-Authors: Diana C Sanchezramirez, M Van Der Esch, Joost Dekker, Marike Van Der Leeden, Martijn Gerritsen, L D Roorda, Jaap H Van Dieen, Sabine Verschueren, Willem F LemsAbstract:Objective. To examine the association of serum CRP and ESR with Muscle Strength in patients with knee OA. Methods. Cross-sectional data from 285 patients with knee OA from the Amsterdam Osteoarthritis (AMS-OA) cohort were analysed. CRP (mg/l) and ESR (mm/l) were measured in serum from patients’ blood samples and the values were dichotomized for the analyses. Strength of quadriceps and hamstring Muscles was assessed using an isokinetic dynamometer. Univariable and multivariable linear regression analyses were used to assess the association of CRP and ESR with Muscle Strength, adjusting for relevant confounders. Results. Elevated levels of serum CRP (� = � 0.10; P = 0.04) and ESR (� = � 0.12; P = 0.02) were associated with lower Muscle Strength after adjustment for age, sex, comorbidities and NSAID use. The associations were no longer significant when BMI was incorporated in the adjusted model. Conclusion. Inflammation might influence Muscle Strength in patients with knee OA. Moreover, the link between inflammation and obesity might explain the effect that BMI has in the associations between inflammatory markers (i.e. CRP and ESR) and Muscle Strength.
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association of lower Muscle Strength with self reported knee instability in osteoarthritis of the knee results from the amsterdam osteoarthritis cohort
Arthritis Care and Research, 2012Co-Authors: J Knoop, M Van Der Esch, Willem F Lems, Joost Dekker, Marike Van Der Leeden, R E Voorneman, Martijn Gerritsen, Carina A Thorstensson, L D Roorda, Martijn SteultjensAbstract:Objective To determine whether Muscle Strength, proprioceptive accuracy, and laxity are associated with self-reported knee instability in a large cohort of knee osteoarthritis (OA) patients, and to investigate whether Muscle Strength may compensate for impairment in proprioceptive accuracy or laxity, in order to maintain knee stability. Methods. Data from 283 knee OA patients from the Amsterdam Osteoarthritis cohort were used. Univariable and multivariable logistic regression analyses were performed to assess the association between Muscle Strength, proprioceptive accuracy (motion sense), frontal plane varus-valgus laxity, and self-reported knee instability. Additionally, effect modification between Muscle Strength and proprioceptive accuracy and between Muscle Strength and laxity was determined. Results. Self-reported knee instability was present in 67% of the knee OA patients and mainly occurred during walking. Lower Muscle Strength was significantly associated with the presence of self-reported knee instability, even after adjusting for relevant confounding. Impaired proprioceptive accuracy and high laxity were not associated with self-reported knee instability. No effect modification between Muscle Strength and proprioceptive accuracy or laxity was found. Conclusion. Lower Muscle Strength is strongly associated with self-reported knee instability in knee OA patients, while impairments in proprioceptive accuracy and laxity are not. A compensatory role of Muscle Strength for impaired proprioceptive accuracy or high laxity, in order to stabilize the knee, could not be demonstrated. (Less)
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joint proprioception Muscle Strength and functional ability in patients with osteoarthritis of the knee
Arthritis & Rheumatism, 2007Co-Authors: M Van Der Esch, Martijn P. M. Steultjens, Dirk L Knol, Jaap Harlaar, Willem F Lems, Joost DekkerAbstract:Objective To test the hypotheses that poor knee joint proprioception is related to limitations in functional ability, and poor proprioception aggravates the impact of Muscle weakness on limitations in functional ability in osteoarthritis (OA) of the knee. Methods Sixty-three patients with symptomatic OA of the knee were tested. Proprioceptive acuity was assessed by establishing the joint motion detection threshold (JMDT) in the anteroposterior direction. Muscle Strength was measured using a computer-driven isokinetic dynamometer. Functional ability was assessed by the 100-meter walking test, the Get Up and Go (GUG) test, and the Western Ontario and McMaster Universities Osteoarthritis Index physical function (WOMAC-PF) questionnaire. Correlation analyses were performed to assess the relationship between proprioception, Muscle Strength, and functional ability. Regression analyses were performed to assess the impact of proprioception on the relationship between Muscle Strength and functional ability. Results Poor proprioception (high JMDT) was related to more limitation in functional ability (walking time r = 0.30, P < 0.05; GUG time r = 0.30, P < 0.05; WOMAC-PF r = 0.26, P <0.05). In regression analyses, the interaction between proprioception and Muscle Strength was significantly related to functional ability (walking time, P < 0.001 and GUG time, P < 0.001) but not to WOMAC-PF score (P = 0.625). In patients with poor proprioception, reduction of Muscle Strength was associated with more severe deterioration of functional ability than in patients with accurate proprioception. Conclusion Patients with poor proprioception show more limitation in functional ability, but this relationship is rather weak. In patients with poor proprioception, Muscle weakness has a stronger impact on limitations in functional ability than in patients with accurate proprioception.
Willem F Lems - One of the best experts on this subject based on the ideXlab platform.
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falls associated with Muscle Strength in patients with knee osteoarthritis and self reported knee instability
The Journal of Rheumatology, 2015Co-Authors: Arjan De Zwart, M Van Der Esch, Willem F Lems, Joost Dekker, Marike Van Der Leeden, L D Roorda, Mirjam Pijnappels, Marco J M Hoozemans, Jaap H Van DieenAbstract:Objective. We aimed to evaluate the associations between knee Muscle Strength (MS) and falls, controlling for knee joint proprioception, varus-valgus knee joint laxity, and knee pain, among patients with knee osteoarthritis (OA) reporting knee instability. Methods. A sample of 301 subjects (203 women, 98 men, 35–82 yrs) with established knee OA and self-reported knee instability was studied. The occurrence of at least 1 fall in the previous 3 months was assessed by questionnaire. Maximum knee extension and flexion Strength were measured isokinetically. Additionally, proprioception, varus-valgus laxity, and pain were assessed. Student t tests were used to assess differences between subgroups. The association of Muscle Strength and falls was calculated using univariate and multivariate logistic regression analysis. Results. Over 10% of the subjects (31 out of 301) reported a fall in the previous 3 months. High knee extension Muscle Strength (crude OR 0.3, 95% CI 0.1–0.8, p = 0.022) and high knee flexion Muscle Strength (crude OR 0.2, 95% CI 0.0–1.0, p = 0.048) were associated with a lower risk of falls. Proprioception and laxity did not confound this relationship. After adjusting for pain, extensor Strength had an adjusted OR of 0.5 (95% CI 0.2–1.4, p = 0.212) for falls and flexor Strength had an adjusted OR of 0.4 (95% CI 0.1–2.3, p = 0.312). Conclusion. High knee extension and flexion Muscle Strength decreased the risk of falls in patients with knee OA and self-reported knee instability. After considering the effect of pain, there was insufficient statistical power to detect an association between Muscle Strength and falls, which might be because of the low number of subjects who fell (n = 31).
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association of serum c reactive protein and erythrocyte sedimentation rate with Muscle Strength in patients with knee osteoarthritis
Rheumatology, 2013Co-Authors: Diana C Sanchezramirez, M Van Der Esch, Joost Dekker, Marike Van Der Leeden, Martijn Gerritsen, L D Roorda, Jaap H Van Dieen, Sabine Verschueren, Willem F LemsAbstract:Objective. To examine the association of serum CRP and ESR with Muscle Strength in patients with knee OA. Methods. Cross-sectional data from 285 patients with knee OA from the Amsterdam Osteoarthritis (AMS-OA) cohort were analysed. CRP (mg/l) and ESR (mm/l) were measured in serum from patients’ blood samples and the values were dichotomized for the analyses. Strength of quadriceps and hamstring Muscles was assessed using an isokinetic dynamometer. Univariable and multivariable linear regression analyses were used to assess the association of CRP and ESR with Muscle Strength, adjusting for relevant confounders. Results. Elevated levels of serum CRP (� = � 0.10; P = 0.04) and ESR (� = � 0.12; P = 0.02) were associated with lower Muscle Strength after adjustment for age, sex, comorbidities and NSAID use. The associations were no longer significant when BMI was incorporated in the adjusted model. Conclusion. Inflammation might influence Muscle Strength in patients with knee OA. Moreover, the link between inflammation and obesity might explain the effect that BMI has in the associations between inflammatory markers (i.e. CRP and ESR) and Muscle Strength.
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association of lower Muscle Strength with self reported knee instability in osteoarthritis of the knee results from the amsterdam osteoarthritis cohort
Arthritis Care and Research, 2012Co-Authors: J Knoop, M Van Der Esch, Willem F Lems, Joost Dekker, Marike Van Der Leeden, R E Voorneman, Martijn Gerritsen, Carina A Thorstensson, L D Roorda, Martijn SteultjensAbstract:Objective To determine whether Muscle Strength, proprioceptive accuracy, and laxity are associated with self-reported knee instability in a large cohort of knee osteoarthritis (OA) patients, and to investigate whether Muscle Strength may compensate for impairment in proprioceptive accuracy or laxity, in order to maintain knee stability. Methods. Data from 283 knee OA patients from the Amsterdam Osteoarthritis cohort were used. Univariable and multivariable logistic regression analyses were performed to assess the association between Muscle Strength, proprioceptive accuracy (motion sense), frontal plane varus-valgus laxity, and self-reported knee instability. Additionally, effect modification between Muscle Strength and proprioceptive accuracy and between Muscle Strength and laxity was determined. Results. Self-reported knee instability was present in 67% of the knee OA patients and mainly occurred during walking. Lower Muscle Strength was significantly associated with the presence of self-reported knee instability, even after adjusting for relevant confounding. Impaired proprioceptive accuracy and high laxity were not associated with self-reported knee instability. No effect modification between Muscle Strength and proprioceptive accuracy or laxity was found. Conclusion. Lower Muscle Strength is strongly associated with self-reported knee instability in knee OA patients, while impairments in proprioceptive accuracy and laxity are not. A compensatory role of Muscle Strength for impaired proprioceptive accuracy or high laxity, in order to stabilize the knee, could not be demonstrated. (Less)
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joint proprioception Muscle Strength and functional ability in patients with osteoarthritis of the knee
Arthritis & Rheumatism, 2007Co-Authors: M Van Der Esch, Martijn P. M. Steultjens, Dirk L Knol, Jaap Harlaar, Willem F Lems, Joost DekkerAbstract:Objective To test the hypotheses that poor knee joint proprioception is related to limitations in functional ability, and poor proprioception aggravates the impact of Muscle weakness on limitations in functional ability in osteoarthritis (OA) of the knee. Methods Sixty-three patients with symptomatic OA of the knee were tested. Proprioceptive acuity was assessed by establishing the joint motion detection threshold (JMDT) in the anteroposterior direction. Muscle Strength was measured using a computer-driven isokinetic dynamometer. Functional ability was assessed by the 100-meter walking test, the Get Up and Go (GUG) test, and the Western Ontario and McMaster Universities Osteoarthritis Index physical function (WOMAC-PF) questionnaire. Correlation analyses were performed to assess the relationship between proprioception, Muscle Strength, and functional ability. Regression analyses were performed to assess the impact of proprioception on the relationship between Muscle Strength and functional ability. Results Poor proprioception (high JMDT) was related to more limitation in functional ability (walking time r = 0.30, P < 0.05; GUG time r = 0.30, P < 0.05; WOMAC-PF r = 0.26, P <0.05). In regression analyses, the interaction between proprioception and Muscle Strength was significantly related to functional ability (walking time, P < 0.001 and GUG time, P < 0.001) but not to WOMAC-PF score (P = 0.625). In patients with poor proprioception, reduction of Muscle Strength was associated with more severe deterioration of functional ability than in patients with accurate proprioception. Conclusion Patients with poor proprioception show more limitation in functional ability, but this relationship is rather weak. In patients with poor proprioception, Muscle weakness has a stronger impact on limitations in functional ability than in patients with accurate proprioception.
