The Experts below are selected from a list of 291 Experts worldwide ranked by ideXlab platform
Martin Hoenigl - One of the best experts on this subject based on the ideXlab platform.
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the role of medical Mycology societies in combating invasive fungal infections in low and middle income countries a nigerian model
Mycoses, 2019Co-Authors: Rita O Oladele, Arunaloke Chakrabarti, Iriagbonse I Osaigbovo, Olusola Ayanlowo, Martin Hoenigl, Oliver A Cornely, David W DenningAbstract:: The discipline of medical Mycology has become increasingly relevant in the face of the rising incidence of invasive fungal infections (IFI), which pose diagnostic and therapeutic challenges for contemporary medical practice. While firmly established in developed countries, medical Mycology remains obscure in many low- and middle-income countries (LMICs). With a teeming vulnerable populace and an incidence rate of 11.8%, Nigeria has one of the highest estimated burdens of invasive fungal infections (IFIs) in the world. Regardless, the scourge of IFIs has remained silent due to a combination of factors principal amongst which are a lack of awareness and dearth in personnel skilled in diagnosis. The present narrative examines the status of medical Mycology practice in Nigeria and chronicles the journey to change the status quo spurred by the Leading International Fungal Education (LIFE)-facilitated burden estimate paper and culminating in the birth of the Medical Mycology Society of Nigeria (MMSN), the pioneer national medical Mycology society in Africa. The prospects of tackling the IFI challenge are highlighted from the perspective of the nascent society.
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global guidelines and initiatives from the european confederation of medical Mycology to improve patient care and research worldwide new leadership is about working together
Mycoses, 2018Co-Authors: Arunaloke Chakrabarti, Martin Hoenigl, Nelesh P Govender, Jeanpierre Gangneux, Esther Segal, Alexandre Alanio, Sharon C A Chen, Ferry HagenAbstract:Invasive mycoses present a global challenge with expansion into new hosts, emergence of new pathogens, and development of multidrug resistance. In parallel, new antifungal agents and advanced laboratory diagnostic systems are being developed. In response to these evolving challenges, the European Confederation of Medical Mycology (ECMM) is committed to providing international expertise, guidance, and leadership with the key objectives of improving diagnosis, treatment, outcome, and survival of persons with invasive fungal diseases. Representing 25 affiliated National Medical Mycology Societies, the ECMM has developed several major ways to achieving these critical objectives: (a) tasking specific medical Mycology working groups; (b) founding the ECMM Academy and Fellow program (FECMM); (c) expanding the goals of ECMM beyond the European region; (d) implementing the ECMM Excellence Centre Initiative in Europe; and (e) the ECMM Global Guidelines and Neglected Orphan Disease Guidance Initiatives focusing on mucormycosis, rare mould diseases, rare yeast diseases, and endemic mycoses. We believe that these important initiatives and other strategies of the ECMM will advance the field of medical Mycology and improve the outcome of patients with invasive mycoses worldwide.
Arunaloke Chakrabarti - One of the best experts on this subject based on the ideXlab platform.
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the role of medical Mycology societies in combating invasive fungal infections in low and middle income countries a nigerian model
Mycoses, 2019Co-Authors: Rita O Oladele, Arunaloke Chakrabarti, Iriagbonse I Osaigbovo, Olusola Ayanlowo, Martin Hoenigl, Oliver A Cornely, David W DenningAbstract:: The discipline of medical Mycology has become increasingly relevant in the face of the rising incidence of invasive fungal infections (IFI), which pose diagnostic and therapeutic challenges for contemporary medical practice. While firmly established in developed countries, medical Mycology remains obscure in many low- and middle-income countries (LMICs). With a teeming vulnerable populace and an incidence rate of 11.8%, Nigeria has one of the highest estimated burdens of invasive fungal infections (IFIs) in the world. Regardless, the scourge of IFIs has remained silent due to a combination of factors principal amongst which are a lack of awareness and dearth in personnel skilled in diagnosis. The present narrative examines the status of medical Mycology practice in Nigeria and chronicles the journey to change the status quo spurred by the Leading International Fungal Education (LIFE)-facilitated burden estimate paper and culminating in the birth of the Medical Mycology Society of Nigeria (MMSN), the pioneer national medical Mycology society in Africa. The prospects of tackling the IFI challenge are highlighted from the perspective of the nascent society.
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global guidelines and initiatives from the european confederation of medical Mycology to improve patient care and research worldwide new leadership is about working together
Mycoses, 2018Co-Authors: Arunaloke Chakrabarti, Martin Hoenigl, Nelesh P Govender, Jeanpierre Gangneux, Esther Segal, Alexandre Alanio, Sharon C A Chen, Ferry HagenAbstract:Invasive mycoses present a global challenge with expansion into new hosts, emergence of new pathogens, and development of multidrug resistance. In parallel, new antifungal agents and advanced laboratory diagnostic systems are being developed. In response to these evolving challenges, the European Confederation of Medical Mycology (ECMM) is committed to providing international expertise, guidance, and leadership with the key objectives of improving diagnosis, treatment, outcome, and survival of persons with invasive fungal diseases. Representing 25 affiliated National Medical Mycology Societies, the ECMM has developed several major ways to achieving these critical objectives: (a) tasking specific medical Mycology working groups; (b) founding the ECMM Academy and Fellow program (FECMM); (c) expanding the goals of ECMM beyond the European region; (d) implementing the ECMM Excellence Centre Initiative in Europe; and (e) the ECMM Global Guidelines and Neglected Orphan Disease Guidance Initiatives focusing on mucormycosis, rare mould diseases, rare yeast diseases, and endemic mycoses. We believe that these important initiatives and other strategies of the ECMM will advance the field of medical Mycology and improve the outcome of patients with invasive mycoses worldwide.
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Survey of laboratory practices for diagnosis of fungal infection in seven Asian countries: An Asia Fungal Working Group (AFWG) initiative.
Medical mycology, 2018Co-Authors: Ariya Chindamporn, Mitzi Chua, Retno Wahyuningsih, Zhengyin Liu, Pei-lun Sun, Ban Hock Tan, Atul Patel, Ruoyu Li, Arunaloke Chakrabarti, Yee-chun ChenAbstract:An online survey of Mycology laboratories in seven Asian countries was conducted to assess the status, competence, and services available. Country representatives from the Asia Fungal Working Group (AFWG) contacted as many laboratories performing Mycology diagnosis as possible in their respective countries, requesting that the laboratory heads complete the online survey. In total, 241 laboratories responded, including 71 in China, 104 in India, 11 in Indonesia, 26 in the Philippines, four in Singapore, 18 in Taiwan, and seven in Thailand. Overall, 129/241 (53.5%) surveyed Mycology laboratories operate as separate designated Mycology laboratories, 75/241 (31.1%) conduct regular formal staff training, 103/241 (42.7%) are accredited, and 88/157 (56.1%) participate in external quality assurance scheme (EQAS) programs. Microscopy and culture methods are available in nearly all laboratories, although few perform DNA sequencing (37/219; 16.9%) or use matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy (MALDI-TOF MS) (27/219; 12.3%) for isolate identification. Antifungal susceptibility testing is performed in 142/241 (58.9%) laboratories, mainly for yeasts. The most commonly performed nonculture diagnostic is cryptococcal antigen testing (66 laboratories), followed by galactomannan testing (55), polymerase chain reaction (PCR) diagnosis (37), and beta-D-glucan testing (24). Therapeutic drug monitoring is conducted in 21 laboratories. There is almost no access to advanced diagnostic tests, like galactomannan, beta-D-glucan, and PCR, in the surveyed laboratories in Indonesia, the Philippines, and Thailand. These results highlight the need for development of quality laboratories, accreditation and training of manpower in existing laboratories, and access to advanced non-culture-based diagnostic tests to facilitate the diagnosis of fungal infections in Asia.
Rifat Atun - One of the best experts on this subject based on the ideXlab platform.
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systematic analysis of funding awarded for Mycology research to institutions in the uk 1997 2010
BMJ Open, 2014Co-Authors: Michael G Head, Joseph R Fitchett, Rifat AtunAbstract:Objectives Fungal infections cause significant global morbidity and mortality. We have previously described the UK investments in global infectious disease research, and here our objective is to describe the investments awarded to UK institutions for Mycology research and outline potential funding gaps in the UK portfolio. Design Systematic analysis. Setting UK institutions carrying out infectious disease research. Primary and secondary outcome measures Primary outcome is the amount of funding and number of studies related to Mycology research. Secondary outcomes are describing the investments made to specific fungal pathogens and diseases, and also the type of science along the R&D value chain. Methods We systematically searched databases and websites for information on research studies from public and philanthropic funding institutions awarded between 1997 and 2010, and highlighted the Mycology-related projects. Results Of 6165 funded studies, we identified 171 studies related to Mycology (total investment £48.4 million, 1.9% of all infection research, with mean annual funding £3.5 million). Studies related to global health represented 5.1% of this funding (£2.4 million, compared with 35.6% of all infectious diseases). Leading funders were the Biotechnology and Biological Sciences Research Council (£14.8 million, 30.5%) and Wellcome Trust (£12.0 million, 24.7%). Preclinical studies received £42.2 million (87.3%), with clinical trials, intervention studies and implementation research in total receiving £6.2 million (12.7%). By institution, University of Aberdeen received most funding (£16.9 million, 35%). Studies investigating antifungal resistance received £1.5 million (3.2%). Conclusions There is little translation of preclinical research into clinical trials or implementation research in spite of substantial disease burden globally, and there are few UK institutions that carry out significant quantities of Mycology research of any type. In the context of global health and the burden of disease in low-income countries, more investment is required for Mycology research.
Maurice Bensoussan - One of the best experts on this subject based on the ideXlab platform.
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Predictive Mycology: some definitions
Cryptogamie Mycologie, 2020Co-Authors: Philippe Dantigny, Audrey Guilmart, Maurice BensoussanAbstract:Predictive Mycology aims at predicting fungal development in foods and raw products. For 25 years, most of the studies concerned food pathogenic bacteria. Recently, there is a growing concern about food contamination by moulds, especially strains responsible for mycotoxins production. This paper advocates the use of specific models for describing germination and growth of fungi.
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basis of predictive Mycology
International Journal of Food Microbiology, 2005Co-Authors: Philippe Dantigny, Audrey Guilmart, Maurice BensoussanAbstract:Abstract For over 20 years, predictive microbiology focused on food-pathogenic bacteria. Few studies concerned modelling fungal development. On one hand, most of food mycologists are not familiar with modelling techniques; on the other hand, people involved in modelling are developing tools dedicated to bacteria. Therefore, there is a tendency to extend the use of models that were developed for bacteria to moulds. However, some mould specificities should be taken into account. The use of specific models for predicting germination and growth of fungi was advocated previously [ Dantigny, P., Guilmart, A., Bensoussan, M., 2003. Basis of predictive Mycology. In Proceedings of the 4th International Conference of Predictive Modelling in Foods. J.F.M. VanImpe, A.H. Geeraerd, I. Leguerinel, P. Mafart (Eds), 15_19 June, Quimper, pp 117_119. ]. This paper provides a short review of fungal modelling studies.
E. B. Gareth Jones - One of the best experts on this subject based on the ideXlab platform.
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Fifty years of marine Mycology
Fungal Diversity, 2011Co-Authors: E. B. Gareth JonesAbstract:Marine fungi have been widely studied over the past millennium and considerable progress has been made in documenting their phylogeny, biodiversity, ultrastructure, ecology, physiology and their ability to cause decay of lignocellulosic compounds. These studies have generated a wealth of publications and this review will focus primarily on research undertaken since 1995. During this period new topics have attracted marine mycologists especially: algicolous and manglicolous fungi, deep sea fungi, planktonic fungi, endophytes of marine plants, and the screening of taxa for new chemical structures and bioactive compounds. This review will also highlight areas that warrant further investigation, including surveys for marine fungi in Africa, artic waters and south America, more detailed studies of their physiology and biochemistry, and to determine the marine origin of so called “marine derived” fungi.
