The Experts below are selected from a list of 3132 Experts worldwide ranked by ideXlab platform
Dennis B Cornfield - One of the best experts on this subject based on the ideXlab platform.
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small lymphocytic lymphoma chronic lymphocytic leukemia in a pelvic Myelolipoma
International Journal of Clinical and Experimental Pathology, 2009Co-Authors: Shereen M F Gheith, Richard Boulay, Dennis B CornfieldAbstract:Myelolipoma is a rare benign tumor composed of mature adipose tissue and normal hematopoietic elements. Extra-adrenal Myelolipomas are extremely rare, with approximately 50% of cases occurring in the presacral region. We report a case of an 85 year old woman who presented with small bowel obstruction relating to a pelvic mass detected on computed tomography (CT) scan. At laparotomy, a 12-cm. pre-sacral mass was resected. Histologic examination showed a Myelolipoma with dense lymphoid aggregates. On immunostains, the lymphoid aggregates showed positivity for CD20, CD5, and CD23, consistent with small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL). Molecular evaluation confirmed the presence of a clonal B-cell lymphocytic proliferation that did not harbor BCL-2 or BCL-1 gene rearrangements. This case represents the first report of a Myelolipoma involved by a non-Hodgkin lymphoma. The unique combination of these findings raises questions about the relationship between the two observed entities. The likeliest scenario is that an unusual benign tumor (Myelolipoma) was colonized by a relatively common systemic hematopoietic neoplasm SLL/CLL, producing a collision tumor.
Khasnabis S - One of the best experts on this subject based on the ideXlab platform.
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Primary mediastinal Myelolipoma
Cleveland Clinic journal of medicine, 1993Co-Authors: Khasnabis SAbstract:Myelolipomas are benign tumors composed of fat cells and mature bone marrow elements. They usually occur in the adrenal glands; fewer than 20 extra-adrenal Myelolipomas have been reported. Myelolipomas may be found in abdominal, pelvic, or mediastinal sites. We report a patient with a right posterior mediastinal Myelolipoma that was successfully resected.
Shereen M F Gheith - One of the best experts on this subject based on the ideXlab platform.
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small lymphocytic lymphoma chronic lymphocytic leukemia in a pelvic Myelolipoma
International Journal of Clinical and Experimental Pathology, 2009Co-Authors: Shereen M F Gheith, Richard Boulay, Dennis B CornfieldAbstract:Myelolipoma is a rare benign tumor composed of mature adipose tissue and normal hematopoietic elements. Extra-adrenal Myelolipomas are extremely rare, with approximately 50% of cases occurring in the presacral region. We report a case of an 85 year old woman who presented with small bowel obstruction relating to a pelvic mass detected on computed tomography (CT) scan. At laparotomy, a 12-cm. pre-sacral mass was resected. Histologic examination showed a Myelolipoma with dense lymphoid aggregates. On immunostains, the lymphoid aggregates showed positivity for CD20, CD5, and CD23, consistent with small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL). Molecular evaluation confirmed the presence of a clonal B-cell lymphocytic proliferation that did not harbor BCL-2 or BCL-1 gene rearrangements. This case represents the first report of a Myelolipoma involved by a non-Hodgkin lymphoma. The unique combination of these findings raises questions about the relationship between the two observed entities. The likeliest scenario is that an unusual benign tumor (Myelolipoma) was colonized by a relatively common systemic hematopoietic neoplasm SLL/CLL, producing a collision tumor.
Claudio Coco - One of the best experts on this subject based on the ideXlab platform.
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Laparoscopic approach for a presacral Myelolipoma resembling a liposarcoma
Journal of surgical case reports, 2018Co-Authors: Gianluca Rizzo, C Coramusi, G. Pietricola, F. Sionne, F Castri, D.p. Pafundi, R Aversa, Claudio CocoAbstract:Myelolipomas are rare benign tumors that are commonly found in the adrenal glands. Extra-adrenal locations are rare, and presacral Myelolipomas represent the most common extra-adrenal location. The differential diagnosis of malignant presacral neoplasms is very challenging. We present a case of a presacral neoplasm that was completely removed with a laparoscopic approach and diagnosed as a Myelolipoma only after pathological examination.
Simone S Aguiar - One of the best experts on this subject based on the ideXlab platform.
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a unique case of synchronous functional adrenocortical adenoma and Myelolipoma within the ectopic adrenal cortex in a child with beckwith wiedemann syndrome
Pathology Research and Practice, 2012Co-Authors: Izilda A Cardinalli, Antonio Goncalves De Oliveirafilho, Maria Jose Mastellaro, Raul C Ribeiro, Simone S AguiarAbstract:We report a unique case of synchronous functional adrenocortical adenoma and an incidental Myelolipoma within ectopic cortical adrenal tissue located in the renal hilum in a child with Beckwith-Wiedemann syndrome and review the association between adrenal gland disorders and Myelolipomas. To the best of our knowledge, this is the first documented case of a simultaneous occurrence of these three conditions. A 17-month-old child with Beckwith-Wiedemann syndrome was diagnosed with a left adrenal tumor during complementary radiologic studies. Biochemical investigation before surgery showed elevated blood levels of cortisol and dehydroepiandrosterone hormones. The patient underwent a left adrenalectomy with ipsilateral renal hilar and intercaval-aortic lymph node dissection. Pathology findings revealed a left adrenocortical adenoma and an incidental Myelolipoma growing within ectopic cortical adrenal tissue in the renal hilum. The patient is doing well and does not have any current health issues. Patients with adrenal cortex disorders, such as hyperplasias and neoplasms, particularly when associated with hormonal imbalances, may have an increased risk of developing Myelolipomas. Whether Beckwith-Wiedemann syndrome may, by itself, contribute to simultaneous occurrence of adrenocortical adenomas and Myelolipomas remains to be clarified.
