The Experts below are selected from a list of 57 Experts worldwide ranked by ideXlab platform
Parthasarathi Das - One of the best experts on this subject based on the ideXlab platform.
-
Stereoselective Preparationof C1-C10 and C11-O14 Fragments of Narbonolide:Exploiting the Versatility of Thiazolidinethione Chiral Auxiliary
Synthesis, 2009Co-Authors: C. Prasad Narasimhulu, Parthasarathi DasAbstract:An efficient stereoselective synthesis of the C1-C10 and C 11-O14 fragments ofnarbonolide, have been accomplished by using a thiazolidinonethione as chiral auxiliary. The stereocenters at C2, C3, C4, C5, C8, and C9 in C1-C10 fragment and C12 and C13 in Cl 1-C14 fragment were generated via asymmetric acyl-thiazolidinethione aldol reactions whereas the stereocenter at C6 was installed by means of Myers Alkylation.
-
Studies towards the total synthesis of narbonolide: stereoselective preparation of the C1–C10 fragment
Tetrahedron Letters, 2008Co-Authors: C. Prasad Narasimhulu, Javed Iqbal, Khagga Mukkanti, Parthasarathi DasAbstract:Abstract An efficient stereoselective synthesis of the C1–C10 fragment of narbonolide is reported. The stereocentres at C2, 3, 4, 5, 8 and 9 in fragment 5 can be generated via an iterative asymmetric acyl-thiazolidinethione aldol reaction, whereas the stereocentre at C6 is installed by means of Myers Alkylation.
C. Prasad Narasimhulu - One of the best experts on this subject based on the ideXlab platform.
-
Stereoselective Preparationof C1-C10 and C11-O14 Fragments of Narbonolide:Exploiting the Versatility of Thiazolidinethione Chiral Auxiliary
Synthesis, 2009Co-Authors: C. Prasad Narasimhulu, Parthasarathi DasAbstract:An efficient stereoselective synthesis of the C1-C10 and C 11-O14 fragments ofnarbonolide, have been accomplished by using a thiazolidinonethione as chiral auxiliary. The stereocenters at C2, C3, C4, C5, C8, and C9 in C1-C10 fragment and C12 and C13 in Cl 1-C14 fragment were generated via asymmetric acyl-thiazolidinethione aldol reactions whereas the stereocenter at C6 was installed by means of Myers Alkylation.
-
Studies towards the total synthesis of narbonolide: stereoselective preparation of the C1–C10 fragment
Tetrahedron Letters, 2008Co-Authors: C. Prasad Narasimhulu, Javed Iqbal, Khagga Mukkanti, Parthasarathi DasAbstract:Abstract An efficient stereoselective synthesis of the C1–C10 fragment of narbonolide is reported. The stereocentres at C2, 3, 4, 5, 8 and 9 in fragment 5 can be generated via an iterative asymmetric acyl-thiazolidinethione aldol reaction, whereas the stereocentre at C6 is installed by means of Myers Alkylation.
Dirk Trauner - One of the best experts on this subject based on the ideXlab platform.
-
Total Synthesis of Sandresolide B and Amphilectolide
Organic letters, 2013Co-Authors: Ingrid Chen, Irina Baitinger, Lucas Schreyer, Dirk TraunerAbstract:The total synthesis of the diterpenoids sandresolide B and amphilectolide from a common furan building block is presented. Key steps include palladium-mediated carbonylation, lanthanide catalyzed ring closure, Myers Alkylation, intramolecular Friedel–Crafts acylation, photooxygenation, and a Kornblum–DeLaMare rearrangement.
Subhash Ghosh - One of the best experts on this subject based on the ideXlab platform.
-
The first total synthesis of (−)-bitungolide E
Tetrahedron Letters, 2011Co-Authors: J. Shashidhar, K. Mahender Reddy, Subhash GhoshAbstract:Abstract The first total synthesis of (−)-bitungolide E is described. The key steps include a Myers’ Alkylation, modified Evans’ syn aldol-reaction, using Crimmins protocol, Sharpless asymmetric epoxidation and ring-closing metathesis reaction.
Emmanuel A. Theodorakis - One of the best experts on this subject based on the ideXlab platform.
-
Synthetic studies on borrelidin: enantioselective synthesis of the C1-C12 fragment.
Organic letters, 2003Co-Authors: Binh G. Vong, Sunny Abraham, And Alan X. Xiang, Emmanuel A. TheodorakisAbstract:An efficient, enantioselective synthesis of the C1−C12 fragment 2 of borrelidin is presented. Construction of the “skipped” polymethylene chain of 2 was accomplished by iteration of Myers' Alkylation, while formation of the C3 stereocenter was achieved by Roush's asymmetric allylboration methodology.
