The Experts below are selected from a list of 171 Experts worldwide ranked by ideXlab platform
Muhammad Chaudhry - One of the best experts on this subject based on the ideXlab platform.
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Myxedema heart disease a rare disease entity case report and brief review of the literature
Current Hypertension Reviews, 2019Co-Authors: Muhammad Chaudhry, Luanda Grazette, Michael W FongAbstract:BACKGROUND: Myxedema heart disease is an extremely rare disease entity and should be suspected in patients with unexplained heart failure refractory to conventional treatment. Myxedema coma with co- existent heart disease is not well known and very few cases have been reported. CONCLUSION: Here, we present an interesting case of Myxedema coma with severe valvular cardiomyopathy followed by a concise review of the literature with special emphasis on epidemiology, pathophysiology, diagnosis and therapeutic modalities.
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Myxedema coma with Myxedema heart disease
Journal of the American College of Cardiology, 2015Co-Authors: Muhammad Chaudhry, Luanda Grazette, Michael Fong, Digant Bhatt, Pradeepto Ghosh, Nagapradeep NagajothiAbstract:Myxedema heart disease is a rare and potentially fatal disease entity. A high index of suspicion in cases of unexplained heart failure with early administration of thyroxine can be potentially lifesaving. A 58 year old woman was admitted with three days of worsening volume overload and marked
F Trimarchi - One of the best experts on this subject based on the ideXlab platform.
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Myxedema coma of both primary and secondary origin with non classic presentation and extremely elevated creatine kinase
Hormone and Metabolic Research, 2000Co-Authors: Salvatore Benvenga, S Squadrito, F Saporito, A Cimino, F Arrigo, F TrimarchiAbstract:: Myxedema coma is a rare, often fatal endocrine emergency that concerns elderly patients with long-standing primary hypothyroidism; Myxedema coma of central origin is exceedingly rare. Here, we report a 37-year-old woman in whom classical symptoms of hypothyroidism had been absent. Six years earlier, she had severe obstetric hemorrhage and, shortly after, two subsequent episodes of pericardial effusion. On the day of admission, pericardiocentesis was performed for the third episode of pericardial effusion. Because of the subsequent grave arrhythmias and unconsciousness, she was transferred to our ICU. Prior to the endocrine consultation, a silent myocardial infarction had been suspected, based on the extremely high serum levels of creatine kinase (CK) and isoenzyme CK-MB. However, based on thyroid sonography, pituitary computed tomography, elevated titers of antithyroid antibodies and pituitary stimulation tests, the final diagnosis was Myxedema coma of dual origin: an atrophic variant of Hashimoto's thyroiditis and post-necrotic pituitary atrophy (Sheehan syndrome). Substitutive therapy caused a prompt clinical amelioration and normalization of CK levels. Our patient is the first case of Myxedema coma of double etiology, and illustrates how its presentation deviates markedly from the one endocrinologists and physicians at ICU are prepared to encounter. In addition, cardiac problems as those of our patient should not discourage from substitutive treatment (using L-thyroxine and the gastrointestinal route of absorption), if the age is relatively low.
Luanda Grazette - One of the best experts on this subject based on the ideXlab platform.
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Myxedema heart disease a rare disease entity case report and brief review of the literature
Current Hypertension Reviews, 2019Co-Authors: Muhammad Chaudhry, Luanda Grazette, Michael W FongAbstract:BACKGROUND: Myxedema heart disease is an extremely rare disease entity and should be suspected in patients with unexplained heart failure refractory to conventional treatment. Myxedema coma with co- existent heart disease is not well known and very few cases have been reported. CONCLUSION: Here, we present an interesting case of Myxedema coma with severe valvular cardiomyopathy followed by a concise review of the literature with special emphasis on epidemiology, pathophysiology, diagnosis and therapeutic modalities.
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Myxedema coma with Myxedema heart disease
Journal of the American College of Cardiology, 2015Co-Authors: Muhammad Chaudhry, Luanda Grazette, Michael Fong, Digant Bhatt, Pradeepto Ghosh, Nagapradeep NagajothiAbstract:Myxedema heart disease is a rare and potentially fatal disease entity. A high index of suspicion in cases of unexplained heart failure with early administration of thyroxine can be potentially lifesaving. A 58 year old woman was admitted with three days of worsening volume overload and marked
Michael W Fong - One of the best experts on this subject based on the ideXlab platform.
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Myxedema heart disease a rare disease entity case report and brief review of the literature
Current Hypertension Reviews, 2019Co-Authors: Muhammad Chaudhry, Luanda Grazette, Michael W FongAbstract:BACKGROUND: Myxedema heart disease is an extremely rare disease entity and should be suspected in patients with unexplained heart failure refractory to conventional treatment. Myxedema coma with co- existent heart disease is not well known and very few cases have been reported. CONCLUSION: Here, we present an interesting case of Myxedema coma with severe valvular cardiomyopathy followed by a concise review of the literature with special emphasis on epidemiology, pathophysiology, diagnosis and therapeutic modalities.
Nagapradeep Nagajothi - One of the best experts on this subject based on the ideXlab platform.
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Myxedema coma with Myxedema heart disease
Journal of the American College of Cardiology, 2015Co-Authors: Muhammad Chaudhry, Luanda Grazette, Michael Fong, Digant Bhatt, Pradeepto Ghosh, Nagapradeep NagajothiAbstract:Myxedema heart disease is a rare and potentially fatal disease entity. A high index of suspicion in cases of unexplained heart failure with early administration of thyroxine can be potentially lifesaving. A 58 year old woman was admitted with three days of worsening volume overload and marked