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Ahmad Ghanizadeh - One of the best experts on this subject based on the ideXlab platform.
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2016Co-Authors: Ahmad Ghanizadeh, Amir Bazrafshan, Ali Firoozabadi, Gholamreza Dehbozorgi MscAbstract:Objective: This is a parallel, three group, randomized, controlled clinical trial, with outcomes evaluated up to three months after randomization for children and adolescents with chronic Nail Biting. The current study investigates the efficacy of habit reversal training (HRT) and compares its effect with object manipulation training (OMT) considering the limitations of the current literature. Method: Ninety one children and adolescents with Nail Biting were randomly allocated to one of the three groups. The three groups were HRT (n=30), OMT (n=30), and wait-list or control group (n=31). The mean length of Nail was considered as the main outcome. Results: The mean length of the Nails after one month in HRT and OMT groups increased compared to the waiting list group (P<0.001, P<0.001, respectively). In long term, both OMT and HRT increased the mean length of Nails (P<0.01), but HRT was more effective than OMT (P<0.021). The parent-reported frequency of Nail Biting did show similar results as to the mean length of Nails assessment in long term. The number of children who completely stopped Nail Biting in HRT and OMT groups during three months was 8 and 7, respectively. This number was zero during one month for the wait-list group. Conclusion: This trial showed that HRT is more effective than wait-list and OMT in increasing the mean length of Nails of children and adolescents in long terms
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a survey of marital satisfaction parenting styles and parent attachment styles in parent of preschool and school children with Nail Biting in compare with control group
2014Co-Authors: Fatemeh Gholami, Ahmad Ghanizadeh, Gholamreza DehbozorgiAbstract:The purpose of this study was to survey the parent-oriented factors such as marital satisfaction, parenting styles and attachment styles in parent of preschool and school children with Nail Biting problem and compare with control group. 400 preschool and school student from 4 district education in Shiraz was selected by available sampling method and their parent were asked to fill in thequestionnaires. Then, data were evaluated by SPSS descriptive, MANOVA and Pearson correlation. Statistical analysis demonstrated that there is no significant differences in parent’s marital satisfaction status and general health status of both groups. The dominant parenting style of both groups was authoritarian style and the dominant attachment style was closeness style.The difference of marital satisfaction, parenting style and attachment style in parent of two groups (Nail Biting and control) is not significant. This factors may not be a interfere variable in children’s Nail Biting.
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n acetylcysteine versus placebo for treating Nail Biting a double blind randomized placebo controlled clinical trial
Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2013Co-Authors: Ahmad Ghanizadeh, Nima Derakhshan, Michael BerkAbstract:Nail Biting is a common behavioral problem. While there are established behavioral interventions for management, they are of modest efficacy, and there is minimal evidence for effective pharmacotherapy. This study investigated the role of N-acetylcysteine (NAC) a potent glutathione and glutamate modulator for the treatment of pathological Nail Biting in children and adolescents. This pilot randomized, double-blind, placebo-controlled clinical trial of NAC (800 mg/day) or placebo enrolled 42 children and adolescents with chronic Nail Biting. Nail length was the objective outcome. Evaluations were carried out three times; before treatment, one month after enrollment in the study, and two months after enrollment. The duration (chronicity) of Nail Biting in the NAC and placebo groups was 3.63(2.45) and 5.09(3.74) years (P=0.14). The mean Nail length gradually increased in both the NAC and placebo groups during this trial. There was a statistically significant difference between the two groups regarding increased Nail length after the first month of trial [(5.21(5.75) and 1.18(3.02) millimeters], however no difference after two months was observed. Two patients in the NAC group discontinued medication due to adverse events. One patient experienced headache, agitation, and social withdrawal, and another patient expressed severe aggression after taking medication and was withdrawn from the study. This study supports the hypothesis that NAC decreases Nail Biting behavior in children and adolescents over the short term. NAC is relatively well tolerated and severe adverse effects are rare. However, there was a high rate of dropout. Further studies with longer durations that build on these preliminary data are recommended. This study is registered at the Iranian Registry of Clinical Trials (Irct registration number: IRCT201103023930N3).
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Habit Reversal Versus Object Manipulation Training for Treating Nail Biting: A Randomized Controlled Clinical Trial
Tehran University of Medical Sciences, 2013Co-Authors: Amir Bazrafshan, Ali Firoozabadi, Gholamreza Dehbozorgi, Ahmad GhanizadehAbstract:Objective:This is a parallel, three group, randomized, controlled clinical trial, with outcomes evaluated up to three months after randomization for children and adolescents with chronic Nail Biting. The current study investigates the efficacy of habit reversal training (HRT) and compares its effect with object manipulation training (OMT) considering the limitations of the current literature .Method:Ninety one children and adolescents with Nail Biting were randomly allocated to one of the three groups. The three groups were HRT (n=30), OMT (n=30), and wait-list or control group (n=31). The mean length of Nail was considered as the main outcome .Results:The mean length of the Nails after one month in HRT and OMT groups increased compared to the waiting list group (P
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Nail Biting etiology consequences and management
Iranian Journal of Medical Sciences, 2011Co-Authors: Ahmad GhanizadehAbstract:Nail Biting (NB) is a common, but unresolved, problem in psychiatry, psychology, medicine and dentistry. While it seems that NB is a simple behavior that can be stopped easily, many of the children with NB have already tried to stop it, but they have not been successful. The frustrations due to failed attempt involve others such as parents and siblings. The present review aims at providing an overview of prevalence, co-morbidities, education and counseling, and management for NB. Overall, the reviewed literatures suggest that co-morbidities of psychiatric disorders and other stereotypic behaviors in clinical sample of children with NB is more than 80%, and more than half of the parents suffer from psychiatric disorders mainly depression. Treatment of NB, however, is not as easy as it seems. The management of NB is much more complicated than just focusing on stopping it. Nail Biting cannot be managed without considering its co-morbidities, antecedents and consequences. It might be concluded form the reviewed literature that children with NB, parents, siblings, and teachers should be educated about what to do and what not to do about NB. Punishment is not effective. Moreover, clinical randomized controlled trials are required to make available evidence-based behavioral and pharmacologic treatment protocols.
Gurveen Chawla - One of the best experts on this subject based on the ideXlab platform.
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chronic Nail Biting orthodontic treatment and enterobacteriaceae in the oral cavity
Journal of Clinical and Experimental Dentistry, 2019Co-Authors: Alagesan Chinnasamy, Karthikeyan Ramalingam, Pallu Chopra, Vidhya Gopinath, Gyanprakash Bishnoi, Gurveen ChawlaAbstract:Background Chronic Nail Biting is common in children and young adults. Auto inoculation of environmental pathogens can manifest as infection in distant organs. Multi-drug resistance gram negative bacteria are on the rise globally. Several of the foodborne bacteria fall within the Enterobacteriaceae family but very few studies have explored these microbes in the oral cavity of children with chronic Nail-Biting habit or orthodontic treatment. The study aims to investigate oral load of Enterobacteriaceae in children with chronic Nail-Biting habit and or those undergoing orthodontic treatment. Material and methods 150 children (no Nail-Biting n=30, Nail Biting n=60, fixed orthodontic treatment n =30 and a combination of fixed orthodontic appliance use and Nail-Biting habit n =30) were assessed for culture based microbiological investigation. The concentrated oral rinse technique was used. The rinse was inoculated in MacConkey's and Blood Agar. The gram stained culture was subjected to biochemical tests for sub-species identification using Biomerieux Vitek 2 Compact Automated Microbiological Analyzer. Fisher's exact and Kruskal Wallis with post hoc analysis using Dunn method was performed to test association and difference between groups. Results Enterobacteriaceae was positive for 72% of the children. Of them, Nail Biting or orthodontic treatment group comprised 89%. Those with a combination of Nail Biting and undergoing orthodontic treatment exhibited highest CFU/ml and those without Nail Biting or orthodontic treatment exhibited the lowest. Three of the four organisms isolated tested positive in the orthodontic treatment group. E. coli was positive in 38% of the children while Klebsiella and E. cloacae were isolated exclusively in the orthodontic treatment group. Conclusions Chronic Nail Biting or the use of fixed orthodontic appliances is associated with higher incidence of Enterobacteriaceae in the oral cavity. Oral health professionals play an important role in preventing multi drug resistance infectious diseases. Key words:Enterobacteriaceae, Nail-Biting, Onychophagia, orthodontic treatment.
Alagesan Chinnasamy - One of the best experts on this subject based on the ideXlab platform.
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chronic Nail Biting orthodontic treatment and enterobacteriaceae in the oral cavity
Journal of Clinical and Experimental Dentistry, 2019Co-Authors: Alagesan Chinnasamy, Karthikeyan Ramalingam, Pallu Chopra, Vidhya Gopinath, Gyanprakash Bishnoi, Gurveen ChawlaAbstract:Background Chronic Nail Biting is common in children and young adults. Auto inoculation of environmental pathogens can manifest as infection in distant organs. Multi-drug resistance gram negative bacteria are on the rise globally. Several of the foodborne bacteria fall within the Enterobacteriaceae family but very few studies have explored these microbes in the oral cavity of children with chronic Nail-Biting habit or orthodontic treatment. The study aims to investigate oral load of Enterobacteriaceae in children with chronic Nail-Biting habit and or those undergoing orthodontic treatment. Material and methods 150 children (no Nail-Biting n=30, Nail Biting n=60, fixed orthodontic treatment n =30 and a combination of fixed orthodontic appliance use and Nail-Biting habit n =30) were assessed for culture based microbiological investigation. The concentrated oral rinse technique was used. The rinse was inoculated in MacConkey's and Blood Agar. The gram stained culture was subjected to biochemical tests for sub-species identification using Biomerieux Vitek 2 Compact Automated Microbiological Analyzer. Fisher's exact and Kruskal Wallis with post hoc analysis using Dunn method was performed to test association and difference between groups. Results Enterobacteriaceae was positive for 72% of the children. Of them, Nail Biting or orthodontic treatment group comprised 89%. Those with a combination of Nail Biting and undergoing orthodontic treatment exhibited highest CFU/ml and those without Nail Biting or orthodontic treatment exhibited the lowest. Three of the four organisms isolated tested positive in the orthodontic treatment group. E. coli was positive in 38% of the children while Klebsiella and E. cloacae were isolated exclusively in the orthodontic treatment group. Conclusions Chronic Nail Biting or the use of fixed orthodontic appliances is associated with higher incidence of Enterobacteriaceae in the oral cavity. Oral health professionals play an important role in preventing multi drug resistance infectious diseases. Key words:Enterobacteriaceae, Nail-Biting, Onychophagia, orthodontic treatment.
David R. Stukus - One of the best experts on this subject based on the ideXlab platform.
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Thumb-Sucking, Nail-Biting, and Atopic Sensitization, Asthma, and Hay Fever
Pediatrics, 2017Co-Authors: Deepa D. Patadia, David R. StukusAbstract:SJ Lynch, MR Sears, RJ Hancox. Pediatrics. 2016;138(2):e20160443 Thumb-sucking and Nail-Biting are common behaviors in children that likely increase exposure to microbes. The hygiene hypothesis suggests that children with early exposure to a more diverse array of microbes may have a decreased risk of developing atopic diseases. The authors of this study examine the relationship between thumb-sucking and Nail-Biting habits in children and the development of atopy. This was a population-based birth cohort with 1037 subjects born in Dunedin, New Zealand. Subjects were managed to age 38 years. Parents were asked to report their children’s thumb-sucking and Nail-Biting behaviors at ages 5, 7, 9, and 11 years. Skin prick testing for common aeroallergens was completed at age 13 years and again at age 32 years. Participants were regarded as having atopic sensitization if …
Gyanprakash Bishnoi - One of the best experts on this subject based on the ideXlab platform.
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chronic Nail Biting orthodontic treatment and enterobacteriaceae in the oral cavity
Journal of Clinical and Experimental Dentistry, 2019Co-Authors: Alagesan Chinnasamy, Karthikeyan Ramalingam, Pallu Chopra, Vidhya Gopinath, Gyanprakash Bishnoi, Gurveen ChawlaAbstract:Background Chronic Nail Biting is common in children and young adults. Auto inoculation of environmental pathogens can manifest as infection in distant organs. Multi-drug resistance gram negative bacteria are on the rise globally. Several of the foodborne bacteria fall within the Enterobacteriaceae family but very few studies have explored these microbes in the oral cavity of children with chronic Nail-Biting habit or orthodontic treatment. The study aims to investigate oral load of Enterobacteriaceae in children with chronic Nail-Biting habit and or those undergoing orthodontic treatment. Material and methods 150 children (no Nail-Biting n=30, Nail Biting n=60, fixed orthodontic treatment n =30 and a combination of fixed orthodontic appliance use and Nail-Biting habit n =30) were assessed for culture based microbiological investigation. The concentrated oral rinse technique was used. The rinse was inoculated in MacConkey's and Blood Agar. The gram stained culture was subjected to biochemical tests for sub-species identification using Biomerieux Vitek 2 Compact Automated Microbiological Analyzer. Fisher's exact and Kruskal Wallis with post hoc analysis using Dunn method was performed to test association and difference between groups. Results Enterobacteriaceae was positive for 72% of the children. Of them, Nail Biting or orthodontic treatment group comprised 89%. Those with a combination of Nail Biting and undergoing orthodontic treatment exhibited highest CFU/ml and those without Nail Biting or orthodontic treatment exhibited the lowest. Three of the four organisms isolated tested positive in the orthodontic treatment group. E. coli was positive in 38% of the children while Klebsiella and E. cloacae were isolated exclusively in the orthodontic treatment group. Conclusions Chronic Nail Biting or the use of fixed orthodontic appliances is associated with higher incidence of Enterobacteriaceae in the oral cavity. Oral health professionals play an important role in preventing multi drug resistance infectious diseases. Key words:Enterobacteriaceae, Nail-Biting, Onychophagia, orthodontic treatment.
