The Experts below are selected from a list of 273 Experts worldwide ranked by ideXlab platform
M L Price - One of the best experts on this subject based on the ideXlab platform.
-
primary systemic amyloid with Nail Dystrophy
Journal of the Royal Society of Medicine, 1995Co-Authors: E K Derrick, M L PriceAbstract:We report a patient with the classical cutaneous findings of primary systemic amyloidosis, due to myeloma. He had developed a Nail Dystrophy, which is a recognized, but rare, feature in systemic amyloid.
Antonella Tosti - One of the best experts on this subject based on the ideXlab platform.
-
trachyonychia and twenty Nail Dystrophy a comprehensive review and discussion of diagnostic accuracy
Skin appendage disorders, 2016Co-Authors: Audrey A Jacobsen, Antonella TostiAbstract:Background/Aims: The term trachyonychia, also known as twenty-Nail Dystrophy, is used to describe thin, brittle Nails with excessive longitudinal ridging. The term twenty-Nail Dystrophy has been incorrectly applied to other conditions that can affect all twenty Nails. Therefore, we have conducted a comprehensive review of the clinical features of trachyonychia and have included a discussion regarding the diagnostic accuracy of this condition in the literature. Methods: In November and December 2015, we conducted a thorough literature search using the following search terms: ‘trachyonychia', ‘twenty Nail Dystrophy', and ‘sandpaper Nails'. Articles that reported the epidemiology, disease associations, clinical presentation, histopathology, and treatment options for trachyonychia were included. Particular attention was given to case reports to identify misdiagnosed cases of twenty-Nail Dystrophy. Results: Our preliminary search yielded 184 results with 72 unique articles ultimately selected for review. Excluded articles included 27 articles in languages other than English, 18 commentaries or reviews, and 67 irrelevant articles. Twelve additional articles described Nail abnormalities clinically different from trachyonychia. Conclusion: Many other conditions can cause widespread Nail Dystrophy. The specific characteristics of trachyonychia need to be considered to make the diagnosis of twenty-Nail Dystrophy.
-
Nail cosmetics in Nail disorders
Journal of Cosmetic Dermatology, 2007Co-Authors: Matilde Iorizzo, Bianca Maria Piraccini, Antonella TostiAbstract:The clinical features of Nail dystrophies depend on the part of the Nail that has been damaged. Due to the important functions of fingerNails and toeNails, any abnormality of the Nail causes impaired function of the hand or foot. Moreover, the aesthetic aspect of the Nail may affect employability, self-esteem, and interaction with other people. Because the Nails are often difficult to treat, cosmetology may be an effective support to medical treatment. Nail cosmetics may help the patient to cope with his or her Nail Dystrophy while waiting for treatment to show its efficacy. It may also be the only choice to hide Nail Dystrophy where the Nail is irreversibly damaged. Nail cosmetics may also function at treatment for onychtillomania, Nail biting, and Nail ingrowing.
-
diagnosis systemic sarcoidosis presenting with Nail Dystrophy
European Journal of Dermatology, 2000Co-Authors: Antonella Tosti, A M Peluso, Cosimo Misciali, Liliana GuerraAbstract:A 47-year-old woman consulted us in May 1995 because of a Nail Dystrophy involving the 2nd finger of both hands which had lasted for 14 years. The clinical history revealed that the patient had suffered from Raynaud's phenomenon since the age of 45. At the clinical examination the terminal phalanx of both the index fingers were considerably shortened and showed a tapered appearance. The fingerNails were also shortened and [...]
-
idiopathic trachyonychia twenty Nail Dystrophy a pathological study of 23 patients
British Journal of Dermatology, 1994Co-Authors: Antonella Tosti, Bianca Maria Piraccini, Federico Bardazzi, P A FantiAbstract:Summary We report the clinical features and pathological findings in 23 patients with idiopathic trachyonychia (twenty-Nail Dystrophy). Clinically, the Nail changes in the majority of patients consisted of the typical ‘sandapered’ appearance, with a rough, Iustreless Nail plate. In some, however, the Nail plate abnormality was less severe, with numerous small, superficial pits, which imparted a shiny appearance to the surface of the Nail. Histology of Nail biopsy specimens showed spongiotic changes in 19 patients, psoriasiform features in three, and features of lichen planus in one patient. The mean follow-up of these patients was 2 years, during which time none developed alopecia areata or mucocutaneous lesions. Idiopathic trachyonychia is therefore a consequence of several inflammatory disorders, which produce a disturbance of Nail matrix kinetics. The course of the inflammation and the extent of the inflammatory process within the Nail matrix produce two different patterns of Nail plate surface abnormalities.
E K Derrick - One of the best experts on this subject based on the ideXlab platform.
-
primary systemic amyloid with Nail Dystrophy
Journal of the Royal Society of Medicine, 1995Co-Authors: E K Derrick, M L PriceAbstract:We report a patient with the classical cutaneous findings of primary systemic amyloidosis, due to myeloma. He had developed a Nail Dystrophy, which is a recognized, but rare, feature in systemic amyloid.
Hiroshi Shimizu - One of the best experts on this subject based on the ideXlab platform.
-
Nail Dystrophy and blisters as sole manifestations in myeloma associated amyloidosis
Journal of The American Academy of Dermatology, 2006Co-Authors: Yasuyuki Fujita, Yukiko Tsujiabe, Kazuko C Satomatsumura, Masashi Akiyama, Hiroshi ShimizuAbstract:We report the case of a 61-year-old Japanese man with IgG λ-type multiple myeloma, who presented with Nail Dystrophy as the initial manifestation of systemic amyloidosis. Subsequently he developed bullous amyloidosis. This report documents these two rare signs of systemic amyloidosis and demonstrates the precise location of cutaneous blister formation and amyloid deposition by fluorescence antigen mapping and electron microscopy.
Brent Kelly - One of the best experts on this subject based on the ideXlab platform.
-
Primary amyloidosis-induced Nail Dystrophy - eScholarship
Dermatology Online Journal, 2020Co-Authors: William Tausend, Megan Neill, Brent KellyAbstract:Primary amyloidosis is caused by a monoclonal proliferation of plasma cells and is capable of producing cutaneous lesions. A 56-year-old male was admitted to the hospital for evaluation of chronic back pain and acute lower extremity weakness. On examination, he was noted to have subungual verrucous plaques with overlying Nail Dystrophy on his bilateral thumbs. A biopsy of one subungual lesion showed a deposition of amorphous material in the dermis that stained with Congo red and crystal violet. These cutaneous lesions ultimately led to the diagnosis of plasma cell dyscrasia and primary amyloidosis. Based on the literature search, primary amyloidosis presenting with this degree of subungual thickening and overlying Nail Dystrophy has not been previously reported.
-
primary amyloidosis induced Nail Dystrophy
Dermatology Online Journal, 2014Co-Authors: William Tausend, Megan Neill, Brent KellyAbstract:Primary amyloidosis is caused by a monoclonal proliferation of plasma cells and is capable of producing cutaneous lesions. A 56-year-old male was admitted to the hospital for evaluation of chronic back pain and acute lower extremity weakness. On examination, he was noted to have subungual verrucous plaques with overlying Nail Dystrophy on his bilateral thumbs. A biopsy of one subungual lesion showed a deposition of amorphous material in the dermis that stained with Congo red and crystal violet. These cutaneous lesions ultimately led to the diagnosis of plasma cell dyscrasia and primary amyloidosis. Based on the literature search, primary amyloidosis presenting with this degree of subungual thickening and overlying Nail Dystrophy has not been previously reported.
