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Olivier Bouchaud - One of the best experts on this subject based on the ideXlab platform.
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Travel-related health events and their risk factors in HIV-infected sub-Saharan migrants living in France and visiting their Native Country: The ANRS VIHVO cohort study.
Travel medicine and infectious disease, 2019Co-Authors: Thierry Pistone, Sophie Abgrall, Nathalie Lele, Olivier Bouchaud, Eric Ouattara, Delphine Gabillard, Alexandre Duvignaud, H. Cordel, Denis Malvy, Michelle BentataAbstract:Abstract Background Literature on health events in HIV-infected travellers is scarce, particularly in sub-Saharan African (SSA) migrants. Methods We investigated health events in HIV-infected SSA migrants living in France during and after travel to their Native Country. All had a pre-travel plasma viral load (pVL) below 200 copies/mL and were on stable combined antiretroviral therapy (cART). Logistic regression models were used to assess the risk factors for at least one adverse health event or febrile event. Results Among 264 HIV migrants, pre-travel median CD4 count was 439/mm3 and 27 migrants (6%) experienced a low-level viremia between 50 and 200 copies/mL. One hundred (38%) experienced at least one event (13 experienced two events). The most common events were gastrointestinal, including diarrhoea (n = 29, 26%), respiratory events (n = 20, 18%), and malaria (n = 17, 15%; 1 death). In multivariable analysis, a pre-travel low-level viremia and a lack of pre-travel medical advice significantly increased the risk for any event (OR 4.31, 95% CI, 1.41–13.1; and OR 3.62, 95% CI, 1.38–9.47; respectively). A lack of pre-travel advice significantly increased the risk for febrile event. Conclusions Early and tailored counselling on pre-travel medical advice regarding diarrhoea and vector-borne diseases prophylactic measures in HIV-infected SSA migrants should be emphasised before travel to Africa.
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factors associated with virological rebound in hiv positive sub saharan migrants living in france after traveling back to their Native Country anrs vihvo 2006 2009 study
Journal of Immigrant and Minority Health, 2019Co-Authors: Jeanmedard Kankou, Nathalie Lele, Bruno Spire, Olivier Bouchaud, Marguerite Guiguet, Maria Patrizia Carrieri, Sophie AbgrallAbstract:In France, around 25% of the estimated number of people living with HIV are migrants, of whom three quarters are from sub-Saharan Africa (SSA). Our objective was to determine factors associated with virological rebound (VR) at the occasion of a transient stay to the Country of origin. HIV-positive migrants from SSA participating to the ANRS-VIHVO adherence study between 2006 and 2009, on effective ART with controlled pre-travel HIV-1 plasma viral load (VL), were included. Outcome was VR, defined as VL ≥ 50 copies/ml at the post-travel visit during the week following the return to France. Among 237 persons (61.6% female, median age 41 years (IQR, 35–47), median time on ART 4.2 years (IQR, 2.2–7.1), 27 (11.4%) experienced VR. The main purpose of the travel was to visit family and median time spent abroad was 5.3 weeks (IQR, 4.1–8.8). The travel was extended longer than anticipated by at least 1 week in 42 individuals (17.7%). In multivariable logistic model, risk factors for VR were male sex [adjusted OR (aOR) 5.1; 95% CI 1.6–16.2)], no employment in France (aOR 2.0; 1.2–3.5), self-reported non-adherence during the trip (aOR 14.9; 4.9–45.9) and PI-containing regimen (aOR 4.6; 1.2–17.6). In another analysis not including self-reported adherence, traveling during Ramadan while respecting the fast (aOR 3.3; 1.2–9.6) and extension of the stay (aOR 3.0; 1.1–7.8) were associated with VR. Virological rebound was partly explained by structural barriers to adherence such as extension of the travel and inadequate management of Ramadan fasting. Individuals’ journeys should be carefully planned with health care providers.
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Visiting one's Native Country: the risks of nonadherence in HIV-infected sub-Saharan migrants--ANRS VIHVO study.
Journal of the International Association of Providers of AIDS Care, 2013Co-Authors: Sophie Abgrall, Lionel Fugon, Nathalie Lele, Estelle Carde, Michelle Bentata, Olivier Patey, Marie-aude Khuong, Bruno Spire, Patrizia Carrieri, Olivier BouchaudAbstract:The aim of this study was to evaluate to what extent travel-related factors may cause adherence failure to antiretroviral therapy (ART) in otherwise adherent migrants when traveling back to Africa. HIV-infected sub-Saharian migrants living in France with a plasma HIV viral load < 200 copies/mL, with no change in ART for ≥3 months and who were about to visit their Native Country for between 2 weeks and 6 months were enrolled for the study. Patients completed a self-administered adherence questionnaire both at enrollment and during the week following their return to France. Adherence failure occurred in 23 (11.5%) of 200 patients. Negative perception about ART effectiveness (adjusted odds ratio = 4.3; 95% confidence interval = 1.3-13.7), unexpected traumatic events during their stay in their Native Country (7.8; 2.3-26.1), and a prolongation of their stay (5.2; 1.4-20.4) were independently associated with a higher likelihood of adherence failure. Owning/renting one’s house in France (0.30; 0.10-0.96), singl...
Sophie Abgrall - One of the best experts on this subject based on the ideXlab platform.
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Travel-related health events and their risk factors in HIV-infected sub-Saharan migrants living in France and visiting their Native Country: The ANRS VIHVO cohort study.
Travel medicine and infectious disease, 2019Co-Authors: Thierry Pistone, Sophie Abgrall, Nathalie Lele, Olivier Bouchaud, Eric Ouattara, Delphine Gabillard, Alexandre Duvignaud, H. Cordel, Denis Malvy, Michelle BentataAbstract:Abstract Background Literature on health events in HIV-infected travellers is scarce, particularly in sub-Saharan African (SSA) migrants. Methods We investigated health events in HIV-infected SSA migrants living in France during and after travel to their Native Country. All had a pre-travel plasma viral load (pVL) below 200 copies/mL and were on stable combined antiretroviral therapy (cART). Logistic regression models were used to assess the risk factors for at least one adverse health event or febrile event. Results Among 264 HIV migrants, pre-travel median CD4 count was 439/mm3 and 27 migrants (6%) experienced a low-level viremia between 50 and 200 copies/mL. One hundred (38%) experienced at least one event (13 experienced two events). The most common events were gastrointestinal, including diarrhoea (n = 29, 26%), respiratory events (n = 20, 18%), and malaria (n = 17, 15%; 1 death). In multivariable analysis, a pre-travel low-level viremia and a lack of pre-travel medical advice significantly increased the risk for any event (OR 4.31, 95% CI, 1.41–13.1; and OR 3.62, 95% CI, 1.38–9.47; respectively). A lack of pre-travel advice significantly increased the risk for febrile event. Conclusions Early and tailored counselling on pre-travel medical advice regarding diarrhoea and vector-borne diseases prophylactic measures in HIV-infected SSA migrants should be emphasised before travel to Africa.
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factors associated with virological rebound in hiv positive sub saharan migrants living in france after traveling back to their Native Country anrs vihvo 2006 2009 study
Journal of Immigrant and Minority Health, 2019Co-Authors: Jeanmedard Kankou, Nathalie Lele, Bruno Spire, Olivier Bouchaud, Marguerite Guiguet, Maria Patrizia Carrieri, Sophie AbgrallAbstract:In France, around 25% of the estimated number of people living with HIV are migrants, of whom three quarters are from sub-Saharan Africa (SSA). Our objective was to determine factors associated with virological rebound (VR) at the occasion of a transient stay to the Country of origin. HIV-positive migrants from SSA participating to the ANRS-VIHVO adherence study between 2006 and 2009, on effective ART with controlled pre-travel HIV-1 plasma viral load (VL), were included. Outcome was VR, defined as VL ≥ 50 copies/ml at the post-travel visit during the week following the return to France. Among 237 persons (61.6% female, median age 41 years (IQR, 35–47), median time on ART 4.2 years (IQR, 2.2–7.1), 27 (11.4%) experienced VR. The main purpose of the travel was to visit family and median time spent abroad was 5.3 weeks (IQR, 4.1–8.8). The travel was extended longer than anticipated by at least 1 week in 42 individuals (17.7%). In multivariable logistic model, risk factors for VR were male sex [adjusted OR (aOR) 5.1; 95% CI 1.6–16.2)], no employment in France (aOR 2.0; 1.2–3.5), self-reported non-adherence during the trip (aOR 14.9; 4.9–45.9) and PI-containing regimen (aOR 4.6; 1.2–17.6). In another analysis not including self-reported adherence, traveling during Ramadan while respecting the fast (aOR 3.3; 1.2–9.6) and extension of the stay (aOR 3.0; 1.1–7.8) were associated with VR. Virological rebound was partly explained by structural barriers to adherence such as extension of the travel and inadequate management of Ramadan fasting. Individuals’ journeys should be carefully planned with health care providers.
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Visiting one's Native Country: the risks of nonadherence in HIV-infected sub-Saharan migrants--ANRS VIHVO study.
Journal of the International Association of Providers of AIDS Care, 2013Co-Authors: Sophie Abgrall, Lionel Fugon, Nathalie Lele, Estelle Carde, Michelle Bentata, Olivier Patey, Marie-aude Khuong, Bruno Spire, Patrizia Carrieri, Olivier BouchaudAbstract:The aim of this study was to evaluate to what extent travel-related factors may cause adherence failure to antiretroviral therapy (ART) in otherwise adherent migrants when traveling back to Africa. HIV-infected sub-Saharian migrants living in France with a plasma HIV viral load < 200 copies/mL, with no change in ART for ≥3 months and who were about to visit their Native Country for between 2 weeks and 6 months were enrolled for the study. Patients completed a self-administered adherence questionnaire both at enrollment and during the week following their return to France. Adherence failure occurred in 23 (11.5%) of 200 patients. Negative perception about ART effectiveness (adjusted odds ratio = 4.3; 95% confidence interval = 1.3-13.7), unexpected traumatic events during their stay in their Native Country (7.8; 2.3-26.1), and a prolongation of their stay (5.2; 1.4-20.4) were independently associated with a higher likelihood of adherence failure. Owning/renting one’s house in France (0.30; 0.10-0.96), singl...
Michelle Bentata - One of the best experts on this subject based on the ideXlab platform.
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Travel-related health events and their risk factors in HIV-infected sub-Saharan migrants living in France and visiting their Native Country: The ANRS VIHVO cohort study.
Travel medicine and infectious disease, 2019Co-Authors: Thierry Pistone, Sophie Abgrall, Nathalie Lele, Olivier Bouchaud, Eric Ouattara, Delphine Gabillard, Alexandre Duvignaud, H. Cordel, Denis Malvy, Michelle BentataAbstract:Abstract Background Literature on health events in HIV-infected travellers is scarce, particularly in sub-Saharan African (SSA) migrants. Methods We investigated health events in HIV-infected SSA migrants living in France during and after travel to their Native Country. All had a pre-travel plasma viral load (pVL) below 200 copies/mL and were on stable combined antiretroviral therapy (cART). Logistic regression models were used to assess the risk factors for at least one adverse health event or febrile event. Results Among 264 HIV migrants, pre-travel median CD4 count was 439/mm3 and 27 migrants (6%) experienced a low-level viremia between 50 and 200 copies/mL. One hundred (38%) experienced at least one event (13 experienced two events). The most common events were gastrointestinal, including diarrhoea (n = 29, 26%), respiratory events (n = 20, 18%), and malaria (n = 17, 15%; 1 death). In multivariable analysis, a pre-travel low-level viremia and a lack of pre-travel medical advice significantly increased the risk for any event (OR 4.31, 95% CI, 1.41–13.1; and OR 3.62, 95% CI, 1.38–9.47; respectively). A lack of pre-travel advice significantly increased the risk for febrile event. Conclusions Early and tailored counselling on pre-travel medical advice regarding diarrhoea and vector-borne diseases prophylactic measures in HIV-infected SSA migrants should be emphasised before travel to Africa.
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Visiting one's Native Country: the risks of nonadherence in HIV-infected sub-Saharan migrants--ANRS VIHVO study.
Journal of the International Association of Providers of AIDS Care, 2013Co-Authors: Sophie Abgrall, Lionel Fugon, Nathalie Lele, Estelle Carde, Michelle Bentata, Olivier Patey, Marie-aude Khuong, Bruno Spire, Patrizia Carrieri, Olivier BouchaudAbstract:The aim of this study was to evaluate to what extent travel-related factors may cause adherence failure to antiretroviral therapy (ART) in otherwise adherent migrants when traveling back to Africa. HIV-infected sub-Saharian migrants living in France with a plasma HIV viral load < 200 copies/mL, with no change in ART for ≥3 months and who were about to visit their Native Country for between 2 weeks and 6 months were enrolled for the study. Patients completed a self-administered adherence questionnaire both at enrollment and during the week following their return to France. Adherence failure occurred in 23 (11.5%) of 200 patients. Negative perception about ART effectiveness (adjusted odds ratio = 4.3; 95% confidence interval = 1.3-13.7), unexpected traumatic events during their stay in their Native Country (7.8; 2.3-26.1), and a prolongation of their stay (5.2; 1.4-20.4) were independently associated with a higher likelihood of adherence failure. Owning/renting one’s house in France (0.30; 0.10-0.96), singl...
Francois Marchal - One of the best experts on this subject based on the ideXlab platform.
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Specific airway resistance in healthy young Vietnamese and Caucasian adults.
Respiratory Physiology & Neurobiology, 2015Co-Authors: Thanh Le Tuan, Ngoc Minh Nguyen, Bruno Demoulin, Claude Bonabel, Phi Linh Nguyen-thi, Cyril Schweitzer, Huyen Thi Nguyen, Silvia Varechova, Iulia Ioan, Francois MarchalAbstract:Abstract In healthy Vietnamese children the respiratory resistance has been suggested to be similar at 110 cm height but larger at 130 cm when compared with data in Caucasians from the literature, suggesting smaller airways in older Vietnamese children ( Vu et al., 2008 ). The hypothesis tested here is whether the difference in airway resistance remains consistent throughout growth, and if it is larger in adult Vietnamese than in Caucasians. Airway resistance and Functional Residual Capacity were measured in healthy young Caucasian and Vietnamese adults in their respective Native Country using identical equipment and protocols. Ninety five subjects in Vietnam (60 males) and 101 in France (41 males) were recruited. Airway resistance was significantly larger in Vietnamese than in Caucasians and in females than in males, consistent with difference in body dimensions. Specific airway resistance however was not different by ethnicity or gender. The findings do not support the hypothesis that airway size at adult age – once normalized for lung volume – differs between Vietnamese and Caucasians.
Nathalie Lele - One of the best experts on this subject based on the ideXlab platform.
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Travel-related health events and their risk factors in HIV-infected sub-Saharan migrants living in France and visiting their Native Country: The ANRS VIHVO cohort study.
Travel medicine and infectious disease, 2019Co-Authors: Thierry Pistone, Sophie Abgrall, Nathalie Lele, Olivier Bouchaud, Eric Ouattara, Delphine Gabillard, Alexandre Duvignaud, H. Cordel, Denis Malvy, Michelle BentataAbstract:Abstract Background Literature on health events in HIV-infected travellers is scarce, particularly in sub-Saharan African (SSA) migrants. Methods We investigated health events in HIV-infected SSA migrants living in France during and after travel to their Native Country. All had a pre-travel plasma viral load (pVL) below 200 copies/mL and were on stable combined antiretroviral therapy (cART). Logistic regression models were used to assess the risk factors for at least one adverse health event or febrile event. Results Among 264 HIV migrants, pre-travel median CD4 count was 439/mm3 and 27 migrants (6%) experienced a low-level viremia between 50 and 200 copies/mL. One hundred (38%) experienced at least one event (13 experienced two events). The most common events were gastrointestinal, including diarrhoea (n = 29, 26%), respiratory events (n = 20, 18%), and malaria (n = 17, 15%; 1 death). In multivariable analysis, a pre-travel low-level viremia and a lack of pre-travel medical advice significantly increased the risk for any event (OR 4.31, 95% CI, 1.41–13.1; and OR 3.62, 95% CI, 1.38–9.47; respectively). A lack of pre-travel advice significantly increased the risk for febrile event. Conclusions Early and tailored counselling on pre-travel medical advice regarding diarrhoea and vector-borne diseases prophylactic measures in HIV-infected SSA migrants should be emphasised before travel to Africa.
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factors associated with virological rebound in hiv positive sub saharan migrants living in france after traveling back to their Native Country anrs vihvo 2006 2009 study
Journal of Immigrant and Minority Health, 2019Co-Authors: Jeanmedard Kankou, Nathalie Lele, Bruno Spire, Olivier Bouchaud, Marguerite Guiguet, Maria Patrizia Carrieri, Sophie AbgrallAbstract:In France, around 25% of the estimated number of people living with HIV are migrants, of whom three quarters are from sub-Saharan Africa (SSA). Our objective was to determine factors associated with virological rebound (VR) at the occasion of a transient stay to the Country of origin. HIV-positive migrants from SSA participating to the ANRS-VIHVO adherence study between 2006 and 2009, on effective ART with controlled pre-travel HIV-1 plasma viral load (VL), were included. Outcome was VR, defined as VL ≥ 50 copies/ml at the post-travel visit during the week following the return to France. Among 237 persons (61.6% female, median age 41 years (IQR, 35–47), median time on ART 4.2 years (IQR, 2.2–7.1), 27 (11.4%) experienced VR. The main purpose of the travel was to visit family and median time spent abroad was 5.3 weeks (IQR, 4.1–8.8). The travel was extended longer than anticipated by at least 1 week in 42 individuals (17.7%). In multivariable logistic model, risk factors for VR were male sex [adjusted OR (aOR) 5.1; 95% CI 1.6–16.2)], no employment in France (aOR 2.0; 1.2–3.5), self-reported non-adherence during the trip (aOR 14.9; 4.9–45.9) and PI-containing regimen (aOR 4.6; 1.2–17.6). In another analysis not including self-reported adherence, traveling during Ramadan while respecting the fast (aOR 3.3; 1.2–9.6) and extension of the stay (aOR 3.0; 1.1–7.8) were associated with VR. Virological rebound was partly explained by structural barriers to adherence such as extension of the travel and inadequate management of Ramadan fasting. Individuals’ journeys should be carefully planned with health care providers.
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Visiting one's Native Country: the risks of nonadherence in HIV-infected sub-Saharan migrants--ANRS VIHVO study.
Journal of the International Association of Providers of AIDS Care, 2013Co-Authors: Sophie Abgrall, Lionel Fugon, Nathalie Lele, Estelle Carde, Michelle Bentata, Olivier Patey, Marie-aude Khuong, Bruno Spire, Patrizia Carrieri, Olivier BouchaudAbstract:The aim of this study was to evaluate to what extent travel-related factors may cause adherence failure to antiretroviral therapy (ART) in otherwise adherent migrants when traveling back to Africa. HIV-infected sub-Saharian migrants living in France with a plasma HIV viral load < 200 copies/mL, with no change in ART for ≥3 months and who were about to visit their Native Country for between 2 weeks and 6 months were enrolled for the study. Patients completed a self-administered adherence questionnaire both at enrollment and during the week following their return to France. Adherence failure occurred in 23 (11.5%) of 200 patients. Negative perception about ART effectiveness (adjusted odds ratio = 4.3; 95% confidence interval = 1.3-13.7), unexpected traumatic events during their stay in their Native Country (7.8; 2.3-26.1), and a prolongation of their stay (5.2; 1.4-20.4) were independently associated with a higher likelihood of adherence failure. Owning/renting one’s house in France (0.30; 0.10-0.96), singl...