The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Alberto Pasetto - One of the best experts on this subject based on the ideXlab platform.
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muscle perfusion and oxygen consumption by Near Infrared Spectroscopy in septic shock and non septic shock patients
Intensive Care Medicine, 2003Co-Authors: Massimo Girardis, L Rinaldi, S Busani, Ivana Flore, Stefano Mauro, Alberto PasettoAbstract:Objective To measure muscle blood flow (Qtis) and oxygen consumption (VO2tis) in septic and non-septic critically ill patients by Near-Infrared Spectroscopy (NIRS).
Luisa Murer - One of the best experts on this subject based on the ideXlab platform.
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Near-Infrared Spectroscopy as continuous real-time monitoring for kidney graft perfusion
Pediatric Nephrology, 2013Co-Authors: Enrico Vidal, Angela Amigoni, Valentina Brugnolaro, Giulia Ghirardo, Piergiorgio Gamba, Andrea Pettenazzo, Giovanni Franco Zanon, Mario Plebani, Chiara Cosma, Luisa MurerAbstract:Background Near-Infrared Spectroscopy (NIRS) is a non-invasive technique designed to study regional oxygenation (rSO2) by measuring the absorption of chromophores. This study investigated the role of NIRS in the real-time monitoring of kidney graft perfusion for 72 h post-transplantation.
Clare E Elwell - One of the best experts on this subject based on the ideXlab platform.
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multi wavelength depth resolved scattering and pathlength corrected in vivo Near Infrared Spectroscopy of brain tissue
IEEE Transactions on Biomedical Engineering, 2010Co-Authors: Ilias Tachtsidis, Chris E Cooper, Terence S Leung, Arnab Ghosh, Martin Smith, Clare E ElwellAbstract:For resolving concentrations of tissue chromophores in the human adult brain with Near-Infrared Spectroscopy it is advantageous to calculate the light scattering and absorption, at multiple wavelengths with some depth resolution. We report a novel methodology that combines multi-distance frequency and broadband spectrometers and we show preliminary results in a healthy young adult during hypo- and hypercapnia.
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illuminating the developing brain the past present and future of functional Near Infrared Spectroscopy
Neuroscience & Biobehavioral Reviews, 2010Co-Authors: Sarah Lloydfox, Anna Blasi, Clare E ElwellAbstract:A decade has passed since Near Infrared Spectroscopy (NIRS) was first applied to functional brain imaging in infants. As part of the team that published the first functional Near Infrared Spectroscopy (fNIRS) infant study in 1998, we have continued to develop and refine both the technology and methods associated with these measurements. The increasing international interest that this technology is generating among neurodevelopmental researchers and the recent technical developments in biomedical optics have prompted us to compile this review of the challenges that have been overcome in this field, and the practicalities of performing fNIRS in infants. We highlight the increasingly diverse and ambitious studies that have been undertaken and review the technological and methodological advances that have been made in the study design, optical probe development, and interpretation and analyses of the haemodynamic response. A strong emphasis is placed on the potential of the technology and future prospects of fNIRS in the field of developmental neuroscience.
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continuous measurement of cerebral oxygenation by Near Infrared Spectroscopy during induction of anesthesia
Anesthesia & Analgesia, 1999Co-Authors: A T Lovell, H Owenreece, M. Smith, Clare E Elwell, Jerry GoldstoneAbstract:UNLABELLED Near Infrared Spectroscopy (NIRS) measures tissue oxygenation continuously at the bedside. Major disturbances of cerebral oxygenation can be detected by using NIRS, but the ability to observe smaller changes is poorly documented. Although anesthetics generally depress cerebral metabolism and enhance oxygen delivery, the administration of etomidate has been associated with cerebral desaturation. We used this difference to study the ability of NIRS to detect the small changes associated with the onset of anesthesia. Thirty-six healthy patients were randomly allocated to have anesthesia induced with either etomidate, propofol, or thiopental. We found that there was a temporal association between the onset of anesthesia and NIRS-derived indices of cerebral oxygenation. Etomidate was associated with a decrease in cerebral oxygenation, whereas propofol and thiopental were associated with an increase in cerebral oxygenation. We conclude that NIRS is capable of detecting the small changes in cerebral oxygenation associated with the induction of general anesthesia and shows promise as a bedside investigational tool for the noninvasive assessment of cerebral oxygenation. IMPLICATIONS We conclude that Near Infrared Spectroscopy is capable of detecting the small changes in cerebral oxygenation associated with the induction of general anesthesia and shows promise as a bedside investigational tool for the noninvasive assessment of cerebral oxygenation.
Kevin K. Mccully - One of the best experts on this subject based on the ideXlab platform.
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skeletal muscle metabolism in endurance athletes with Near Infrared Spectroscopy
Medicine and Science in Sports and Exercise, 2013Co-Authors: Jared T Brizendine, Rebecca D Larson, Terence E Ryan, Kevin K. MccullyAbstract:BRIZENDINE, J. T., T. E. RYAN, R. D. LARSON, and K. K. MCCULLY. Skeletal Muscle Metabolism in Endurance Athletes with Near-Infrared Spectroscopy. Med. Sci. Sports Exerc., Vol. 45, No. 5, pp. 869-875, 2013. Purpose: To determine whether Near-Infrared Spectroscopy (NIRS) measurements of muscle mitochondrial function could detect the expected differences between endurance-trained athletes (n = 8) and inactive subjects (n = 8). Methods: Muscle oxygen consumption (mVO2) of the vastus lateralis was measured with continuous-wave NIRS using transient arterial occlusions. The recovery rate of mVO2 after electrical stimulation was fit to an expo- nential curve, with the time constant (Tc) used as an index of mitochondrial capacity. Whole-body peak oxygen uptake was determined by indirect calorimetry during a continuous ramp protocol on a cycle ergometer. Results: Whole-body peak oxygen uptake values for endurance-trained and inactive controls were 73.5 T 9.1 and 33.7 T 5.9 mLIkg j1 Imin j1 , respectively (P G 0.001). The recovery rates of mVO2 after exercise for endurance training were 18.4 T 3.2 and 18.8 T 2.5 s, whereas those for inactive controls were 32.4 T 5.2 and 34.9 T 5.9 s for the shallow and deep channels, respectively (P G 0.001 for comparison between groups). Resting mVO2 was 0.52%Is j1 T 0.22%Is j1 for endurance athletes and 0.77%Is j1 T 0.82%Is j1 for inactive controls (P = 0.42). Conclusions: The recovery rates of mVO2 after exercise in endurance athletes were almost twofold faster than inactive subjects measured with NIRS, consistent with previous studies using muscle biopsies and magnetic resonance Spectroscopy. Our results support the use of NIRS measurements of the recovery of oxygen consumption to assess muscle oxidative capacity. Key Words: NIRS, MITOCHONDRIAL CAPACITY, ELECTRICAL STIMULATION, OXIDATIVE METABOLISM, ENDURANCE TRAINING, MAXIMAL OXYGEN UPTAKE, COMPETITIVE CYCLISTS
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a comparison of exercise type and intensity on the noninvasive assessment of skeletal muscle mitochondrial function using Near Infrared Spectroscopy
Journal of Applied Physiology, 2013Co-Authors: Terence E Ryan, Jared T Brizendine, Kevin K. MccullyAbstract:Near-Infrared Spectroscopy (NIRS) can be used to measure muscle oxygen consumption (mVO2) using arterial occlusions. The recovery rate of mVO2 after exercise can provide an index of skeletal muscle...
Charles W Hogue - One of the best experts on this subject based on the ideXlab platform.
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cerebral Near Infrared Spectroscopy monitoring and neurologic outcomes in adult cardiac surgery patients a systematic review
Anesthesia & Analgesia, 2013Co-Authors: Fei Zheng, Rosanne Sheinberg, May Sann Yee, Masa Ono, Yueyging Zheng, Charles W HogueAbstract:Background Near-Infrared Spectroscopy is used during cardiac surgery to monitor the adequacy of cerebral perfusion. In this systematic review, we evaluated available data for adult patients to determine (1) whether decrements in cerebral oximetry during cardiac surgery are associated with stroke, postoperative cognitive dysfunction (POCD), or delirium and (2) whether interventions aimed at correcting cerebral oximetry decrements improve neurologic outcomes.
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real time continuous monitoring of cerebral blood flow autoregulation using Near Infrared Spectroscopy in patients undergoing cardiopulmonary bypass
Stroke, 2010Co-Authors: Kenneth Martin Brady, Peter Smielewski, Marek Czosnyka, Christian Zweifel, Brijen Joshi, Blaine R Easley, Charles W HogueAbstract:Background and Purpose—Individualizing mean arterial blood pressure targets to a patient’s cerebral blood flow autoregulatory range might prevent brain ischemia for patients undergoing cardiopulmonary bypass (CPB). This study compares the accuracy of real-time cerebral blood flow autoregulation monitoring using Near-Infrared Spectroscopy with that of transcranial Doppler. Methods—Sixty adult patients undergoing CPB had transcranial Doppler monitoring of middle cerebral artery blood flow velocity and Near-Infrared Spectroscopy monitoring. The mean velocity index (Mx) was calculated as a moving, liNear correlation coefficient between slow waves of middle cerebral artery blood flow velocity and mean arterial blood pressure. The cerebral oximetry index was calculated as a similar coefficient between slow waves of cerebral oximetry and mean arterial blood pressure. When cerebral blood flow is autoregulated, Mx and cerebral oximetry index vary around zero. Loss of autoregulation results in progressively more po...
