The Experts below are selected from a list of 1194 Experts worldwide ranked by ideXlab platform
Jonathan S. Abramowitz - One of the best experts on this subject based on the ideXlab platform.
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Fear of Needles and vasovagal reactions among phlebotomy patients
Journal of anxiety disorders, 2006Co-Authors: Brett J. Deacon, Jonathan S. AbramowitzAbstract:Anxiety associated with blood and injections is a common problem in medical settings and, in severe cases, affects sufferers' ability to receive medically essential treatment. The present study was conducted to examine incidence of adverse reactions to venipunctures among phlebotomy patients, as well as to understand the demographic and psychological characteristics associated with such reactions. A large sample of participants undergoing venipuncture (N=3315) was recruited from hospital-based phlebotomy laboratories. Participants completed a brief questionnaire assessing psychological and physiological reactions to having their blood drawn. Results indicated that a small minority of patients experienced significant anxiety symptoms during venipuncture. Vasovagal reactions and vasovagal syncope were extremely infrequent. A tendency to experience pain, disgust, and fear of fainting during injections was associated with anxious responding to the venipuncture and a probable diagnosis of Needle Phobia. Theoretical and practical implications are discussed.
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fear of Needles and vasovagal reactions among phlebotomy patients
Journal of Anxiety Disorders, 2006Co-Authors: Brett J. Deacon, Jonathan S. AbramowitzAbstract:Anxiety associated with blood and injections is a common problem in medical settings and, in severe cases, affects sufferers’ ability to receive medically essential treatment. The present study was conducted to examine incidence of adverse reactions to venipunctures among phlebotomy patients, as well as to understand the demographic and psychological characteristics associated with such reactions. A large sample of participants undergoing venipuncture (N = 3315) was recruited from hospital-based phlebotomy laboratories. Participants completed a brief questionnaire assessing psychological and physiological reactions to having their blood drawn. Results indicated that a small minority of patients experienced significant anxiety symptoms during venipuncture. Vasovagal reactions and vasovagal syncope were extremely infrequent. A tendency to experience pain, disgust, and fear of fainting during injections was associated with anxious responding to the venipuncture and a probable diagnosis of Needle Phobia. Theoretical and practical implications are discussed. # 2006 Elsevier Ltd. All rights reserved.
Samir Mitragotri - One of the best experts on this subject based on the ideXlab platform.
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Micro-scale devices for transdermal drug delivery
International Journal of Pharmaceutics, 2008Co-Authors: Anubhav Arora, Mark R Prausnitz, Samir MitragotriAbstract:Skin makes an excellent site for drug and vaccine delivery due to easy accessibility, immuno-surveillance functions, avoidance of macromolecular degradation in the gastrointestinal tract and possibility of self-administration. However, macromolecular drug delivery across the skin is primarily accomplished using hypodermic Needles, which have several disadvantages including accidental Needle-sticks, pain and Needle Phobia. These limitations have led to extensive research and development of alternative methods for drug and vaccine delivery across the skin. This review focuses on the recent trends and developments in this field of micro-scale devices for transdermal macromolecular delivery. These include liquid jet injectors, powder injectors, microNeedles and thermal microablation. The historical perspective, mechanisms of action, important design parameters, applications and challenges are discussed for each method. ?? 2008.
K. Jenkins - One of the best experts on this subject based on the ideXlab platform.
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doi:10.1093/bja/aeu013 EDITORIAL Needle Phobia: a psychological perspective
2016Co-Authors: K. JenkinsAbstract:Needle Phobia is probably seen as a simple issue in its purest form. Your patient does not like Needles—who does? Use a good topical numbing agent and let’s get on with it. Job done... Or is it? When I first started out as a clinical psychologist in a district general hospital, I have to admit that the anaesthetists were not a group I saw myself having a lot to do with. Since then, I have learned that my colleagues in the anaesthetics depart-ment encounter some of the most difficult situations, the shar-pest edges of human distress. Far from being people who only deal with sedated patients, anaesthetists end up dealing with some of the most extraordinary situations with complex psy-chological trauma involved. I now work regularly with the team in a variety of settings and have an enormous amount of respect for their psychological management skills
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II. Needle Phobia: a psychological perspective
British journal of anaesthesia, 2014Co-Authors: K. JenkinsAbstract:Needle Phobia is probably seen as a simple issue in its purest form. Your patient does not like Needles—who does? Use a good topical numbing agent and let’s get on with it. Job done ... Or is it? When I first started out as a clinical psychologist in a district general hospital, I have to admit that the anaesthetists were not a group I saw myself having a lot to do with. Since then, I have learned that my colleagues in the anaesthetics department encounter some of the most difficult situations, the sharpest edges of human distress. Far from being people who only deal with sedated patients, anaesthetists end up dealing with some of the most extraordinary situations with complex psychological trauma involved. I now work regularly with the team in a variety of settings and have an enormous amount of respect for their psychological management skills. I was heartened to see in the November 2013 Bulletin of the Royal College of Anaesthetists, an article on anaesthesia of the anxious and agitated child. 1 As I hope to discuss below, early experiences in the anaesthetic room can have an enormous impact on a person’s future engagement with the healthcare system. Regardless of the problem that child is being sedated for here and now and the problems with pain, recovery, and behaviour postoperatively, described by Marshall and Courtman, the patient’s experience could make the difference in whether they seek medical help in the future or not, even to the extent of refusing life-saving interventions further down the line. Good management of Needle Phobia can literally save lives. The very nature of Needle Phobia makes it very hard to determine incidence. By definition, people who suffer from Needle Phobia will avoid healthcare settings and so any population estimate is likely to underrate the true number, but estimates range from 3.5 to 10%. 23
Brett J. Deacon - One of the best experts on this subject based on the ideXlab platform.
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Fear of Needles and vasovagal reactions among phlebotomy patients
Journal of anxiety disorders, 2006Co-Authors: Brett J. Deacon, Jonathan S. AbramowitzAbstract:Anxiety associated with blood and injections is a common problem in medical settings and, in severe cases, affects sufferers' ability to receive medically essential treatment. The present study was conducted to examine incidence of adverse reactions to venipunctures among phlebotomy patients, as well as to understand the demographic and psychological characteristics associated with such reactions. A large sample of participants undergoing venipuncture (N=3315) was recruited from hospital-based phlebotomy laboratories. Participants completed a brief questionnaire assessing psychological and physiological reactions to having their blood drawn. Results indicated that a small minority of patients experienced significant anxiety symptoms during venipuncture. Vasovagal reactions and vasovagal syncope were extremely infrequent. A tendency to experience pain, disgust, and fear of fainting during injections was associated with anxious responding to the venipuncture and a probable diagnosis of Needle Phobia. Theoretical and practical implications are discussed.
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fear of Needles and vasovagal reactions among phlebotomy patients
Journal of Anxiety Disorders, 2006Co-Authors: Brett J. Deacon, Jonathan S. AbramowitzAbstract:Anxiety associated with blood and injections is a common problem in medical settings and, in severe cases, affects sufferers’ ability to receive medically essential treatment. The present study was conducted to examine incidence of adverse reactions to venipunctures among phlebotomy patients, as well as to understand the demographic and psychological characteristics associated with such reactions. A large sample of participants undergoing venipuncture (N = 3315) was recruited from hospital-based phlebotomy laboratories. Participants completed a brief questionnaire assessing psychological and physiological reactions to having their blood drawn. Results indicated that a small minority of patients experienced significant anxiety symptoms during venipuncture. Vasovagal reactions and vasovagal syncope were extremely infrequent. A tendency to experience pain, disgust, and fear of fainting during injections was associated with anxious responding to the venipuncture and a probable diagnosis of Needle Phobia. Theoretical and practical implications are discussed. # 2006 Elsevier Ltd. All rights reserved.
Anubhav Arora - One of the best experts on this subject based on the ideXlab platform.
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Liquid and Powder Jet Injectors in Drug Delivery: Mechanisms, Designs, and Applications
Percutaneous Penetration Enhancers Physical Methods in Penetration Enhancement, 2017Co-Authors: Anubhav AroraAbstract:Delivery of macromolecules is primarily achieved by the use of hypodermic Needles, which have several disadvantages including accidental Needlesticks, pain, and Needle Phobia. These limitations have led to extensive research and development of alternative methods for drug and vaccine delivery across the skin, without the use of Needles. Jet injectors are one such class of Needle-free devices, which have been used to deliver both liquid and solid drug and vaccine formulations. In spite of their availability for research and clinical use for the past several decades, these devices have had limited acceptance. The mechanism of operation of these devices, the enhanced skin penetration of drugs, device design parameters, applications, and safety concerns for these two types of injection devices are described. Current developments in the field have also been discussed.
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Micro-scale devices for transdermal drug delivery
International Journal of Pharmaceutics, 2008Co-Authors: Anubhav Arora, Mark R Prausnitz, Samir MitragotriAbstract:Skin makes an excellent site for drug and vaccine delivery due to easy accessibility, immuno-surveillance functions, avoidance of macromolecular degradation in the gastrointestinal tract and possibility of self-administration. However, macromolecular drug delivery across the skin is primarily accomplished using hypodermic Needles, which have several disadvantages including accidental Needle-sticks, pain and Needle Phobia. These limitations have led to extensive research and development of alternative methods for drug and vaccine delivery across the skin. This review focuses on the recent trends and developments in this field of micro-scale devices for transdermal macromolecular delivery. These include liquid jet injectors, powder injectors, microNeedles and thermal microablation. The historical perspective, mechanisms of action, important design parameters, applications and challenges are discussed for each method. ?? 2008.
