The Experts below are selected from a list of 5289 Experts worldwide ranked by ideXlab platform
Bhumika T Venkatesh - One of the best experts on this subject based on the ideXlab platform.
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Factors associated with Neonatal Pneumonia in India: protocol for a systematic review and planned meta-analysis.
BMJ open, 2018Co-Authors: Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounts for more Neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of Pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of Pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on Neonatal Pneumonia in India. English language observational studies which report risk factors and determinants of Neonatal Pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using ‘Assessing the Methodological quality of Systematic Reviews’ and ‘Grades of Recommendation, Assessment, Development and Evaluation’. Ethics and dissemination The protocol of the entire project has been approved by the host institution’s ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the ‘Health Ministry Screening Committee’ under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.
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Risk factors and barriers to case management of Neonatal Pneumonia: protocol for a pan-India qualitative study of stakeholder perceptions
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounted for more Neonatal deaths (estimated at 696 000) than any other country, as of 2015. Of these , most Neonatal deaths due to infections can be attributed to Pneumonia which accounts for 16% of all Neonatal mortalities (2010). Despite simple, inexpensive case management strategies being available, Pneumonia continues to cause significant mortality and morbidity among neonates. Understanding the perceptions and experiences of stakeholders of Neonatal care can help find solutions to barriers to care and design tailored strategies for controlling Neonatal Pneumonia. Methods and analysis A pan-India qualitative study will be conducted. Participants include healthcare providers, programme officers, academicians, representatives of non-governmental organisations/bilateral agencies and policy makers. They will be recruited purposively from rural and urban, public and private, and facility and community healthcare settings across six Indian regions. Within each region, a minimum of one state will be selected. Districts will be based on Neonatal mortality indicators, and will be subject to feasibility at the time of conducting the study. We plan to conduct in-depth interviews (IDI) and focus group discussions focusing on (a) burden, (b) risk factors, (c) case management, (d) treatment guidelines, (e) barriers to case management, (f) recommendations. The number of interviews will depend on the information saturation. Interviews will be audio-recorded with prior written consent and transcribed verbatim. Principles of thematic analysis will be applied for qualitative data analysis using R package for Qualitative Data Analysis (RQDA). Ethics and dissemination The protocol has been approved by the Health Ministry Screening Committee, Government of India and the Institutional Ethics Committee at the host institution. Confidentiality and privacy of the participants will be maintained. The findings of the study will be shared with all stakeholders of this research including the participants. Knowledge dissemination workshops will be conducted to ultimately transfer the evidence tailored to the stakeholders9 need.
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Treatment options and barriers to case management of Neonatal Pneumonia in India: a protocol for a scoping review
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest Neonatal deaths globally. Case management is said to be the cornerstone of Pneumonia control. Much of the published evidence focuses on children aged 1 to 59 months. This scoping review, thus, aims to identify the treatment options for and barriers to case management of Neonatal Pneumonia in India. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Studies addressing treatment of or barriers to case management of Neonatal Pneumonia in Indian context, published in English in peer-reviewed and indexed journals will be eligible for inclusion. Electronic search will be conducted on nine databases. Hand searching and snowballing will be done for published and grey literature. Selection of studies will be done in title, abstract and full-text stages. A narrative summary will be performed to summarise the details of evidence. Ethics and dissemination As this is a review involving analysis of secondary data which is available in the public domain and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to ultimately transfer the evidence tailored to the stakeholder (eg, policy briefs, publications, information booklets and so on). PROSPERO 2016 CRD42016045449
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Factors associated with mortality due to Neonatal Pneumonia in India: a protocol for systematic review and planned meta-analysis
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest number of Neonatal deaths globally. It also has the greatest number of Pneumonia-related Neonatal deaths in the developing world. We aim to systematically review the evidence for the factors associated with mortality due to Neonatal Pneumonia in the Indian context, to address the lack of consolidated evidence on this important issue. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Observational studies reporting on outcome of Neonatal Pneumonia in the Indian context, and published in English in peer-reviewed and indexed journals will be eligible for inclusion. Outcomes of this review will be the factors determining mortality due to Neonatal Pneumonia. A total of nine databases will be searched. Electronic and hand searching of published and grey literature will be performed. Selection of studies will be done in title, abstract and full text screening stages. Risk of bias, independently assessed by two authors, will be evaluated. Meta-analysis will be performed and heterogeneity assessed. Pooled effect estimates will be stated with 95% confidence intervals. Narrative synthesis will be done where meta-analysis cannot be performed. Publication bias will be evaluated and sensitivity analysis performed according to study quality. Quality of this review will be evaluated using AMSTAR (Assessing the Methodological quality of Systematic Reviews) and GRADE (Grades of Recommendation, Assessment, Development & Evaluation). A summary of findings table will be reported using GRADEPro. Ethics and dissemination Since this is a review involving analysis of secondary data which is available in the public domain, and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to transfer the evidence, tailored to the stakeholder (eg, policy briefs, publications, information booklets, etc).
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A scoping review on barriers to case management of Neonatal Pneumonia in India
Clinical Epidemiology and Global Health, 1Co-Authors: N Sreekumaran Nair, Leslie Lewis, Vijay Shree Dhyani, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Prachi Pundir, Bhumika T VenkateshAbstract:Abstract Background Neonatal Pneumonia is one of the leading factors contributing to Neonatal mortality. The objective of this review was to identify the barriers associated with case management of Neonatal Pneumonia in India by conducting a scoping review. Methods Nine databases (PubMed, ProQuest, Ovid Medline, CINAHL, Web of Science, EMBASE, IndMED, SCOPUS and WHOLIS) were searched to identify relevant studies in India. The population of interest were neonates. Outcome of interest was barriers associated with case management of Neonatal Pneumonia. Data was charted and reported in accordance with the ‘guidance for conducting systematic scoping reviews'. Results From 5942 citations screened, 244 articles underwent full text screening and two studies with qualitative information met the eligibility criteria. Barriers were classified as patient-related, caregiver-related and healthcare delivery system-related. Delay in seeking care was due to spiritual healers being first point of contact in addition to traditional and home remedies tried by mothers at home and inaccessible healthcare mostly owing to healthcare delivery system were some of the major barriers associated with case management of Neonatal Pneumonia. Conclusion This scoping review concludes that there is a paucity of studies on Neonatal Pneumonia in India particularly with respect to barriers to case management and that many of the barriers described here are applicable to a broad range of Neonatal disease conditions which occur in the community and not just specific to Neonatal Pneumonia.
N Sreekumaran Nair - One of the best experts on this subject based on the ideXlab platform.
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Risk factors and barriers to case management of Neonatal Pneumonia: protocol for a pan-India qualitative study of stakeholder perceptions
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounted for more Neonatal deaths (estimated at 696 000) than any other country, as of 2015. Of these , most Neonatal deaths due to infections can be attributed to Pneumonia which accounts for 16% of all Neonatal mortalities (2010). Despite simple, inexpensive case management strategies being available, Pneumonia continues to cause significant mortality and morbidity among neonates. Understanding the perceptions and experiences of stakeholders of Neonatal care can help find solutions to barriers to care and design tailored strategies for controlling Neonatal Pneumonia. Methods and analysis A pan-India qualitative study will be conducted. Participants include healthcare providers, programme officers, academicians, representatives of non-governmental organisations/bilateral agencies and policy makers. They will be recruited purposively from rural and urban, public and private, and facility and community healthcare settings across six Indian regions. Within each region, a minimum of one state will be selected. Districts will be based on Neonatal mortality indicators, and will be subject to feasibility at the time of conducting the study. We plan to conduct in-depth interviews (IDI) and focus group discussions focusing on (a) burden, (b) risk factors, (c) case management, (d) treatment guidelines, (e) barriers to case management, (f) recommendations. The number of interviews will depend on the information saturation. Interviews will be audio-recorded with prior written consent and transcribed verbatim. Principles of thematic analysis will be applied for qualitative data analysis using R package for Qualitative Data Analysis (RQDA). Ethics and dissemination The protocol has been approved by the Health Ministry Screening Committee, Government of India and the Institutional Ethics Committee at the host institution. Confidentiality and privacy of the participants will be maintained. The findings of the study will be shared with all stakeholders of this research including the participants. Knowledge dissemination workshops will be conducted to ultimately transfer the evidence tailored to the stakeholders9 need.
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Treatment options and barriers to case management of Neonatal Pneumonia in India: a protocol for a scoping review
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest Neonatal deaths globally. Case management is said to be the cornerstone of Pneumonia control. Much of the published evidence focuses on children aged 1 to 59 months. This scoping review, thus, aims to identify the treatment options for and barriers to case management of Neonatal Pneumonia in India. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Studies addressing treatment of or barriers to case management of Neonatal Pneumonia in Indian context, published in English in peer-reviewed and indexed journals will be eligible for inclusion. Electronic search will be conducted on nine databases. Hand searching and snowballing will be done for published and grey literature. Selection of studies will be done in title, abstract and full-text stages. A narrative summary will be performed to summarise the details of evidence. Ethics and dissemination As this is a review involving analysis of secondary data which is available in the public domain and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to ultimately transfer the evidence tailored to the stakeholder (eg, policy briefs, publications, information booklets and so on). PROSPERO 2016 CRD42016045449
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Factors associated with mortality due to Neonatal Pneumonia in India: a protocol for systematic review and planned meta-analysis
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest number of Neonatal deaths globally. It also has the greatest number of Pneumonia-related Neonatal deaths in the developing world. We aim to systematically review the evidence for the factors associated with mortality due to Neonatal Pneumonia in the Indian context, to address the lack of consolidated evidence on this important issue. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Observational studies reporting on outcome of Neonatal Pneumonia in the Indian context, and published in English in peer-reviewed and indexed journals will be eligible for inclusion. Outcomes of this review will be the factors determining mortality due to Neonatal Pneumonia. A total of nine databases will be searched. Electronic and hand searching of published and grey literature will be performed. Selection of studies will be done in title, abstract and full text screening stages. Risk of bias, independently assessed by two authors, will be evaluated. Meta-analysis will be performed and heterogeneity assessed. Pooled effect estimates will be stated with 95% confidence intervals. Narrative synthesis will be done where meta-analysis cannot be performed. Publication bias will be evaluated and sensitivity analysis performed according to study quality. Quality of this review will be evaluated using AMSTAR (Assessing the Methodological quality of Systematic Reviews) and GRADE (Grades of Recommendation, Assessment, Development & Evaluation). A summary of findings table will be reported using GRADEPro. Ethics and dissemination Since this is a review involving analysis of secondary data which is available in the public domain, and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to transfer the evidence, tailored to the stakeholder (eg, policy briefs, publications, information booklets, etc).
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A scoping review on barriers to case management of Neonatal Pneumonia in India
Clinical Epidemiology and Global Health, 1Co-Authors: N Sreekumaran Nair, Leslie Lewis, Vijay Shree Dhyani, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Prachi Pundir, Bhumika T VenkateshAbstract:Abstract Background Neonatal Pneumonia is one of the leading factors contributing to Neonatal mortality. The objective of this review was to identify the barriers associated with case management of Neonatal Pneumonia in India by conducting a scoping review. Methods Nine databases (PubMed, ProQuest, Ovid Medline, CINAHL, Web of Science, EMBASE, IndMED, SCOPUS and WHOLIS) were searched to identify relevant studies in India. The population of interest were neonates. Outcome of interest was barriers associated with case management of Neonatal Pneumonia. Data was charted and reported in accordance with the ‘guidance for conducting systematic scoping reviews'. Results From 5942 citations screened, 244 articles underwent full text screening and two studies with qualitative information met the eligibility criteria. Barriers were classified as patient-related, caregiver-related and healthcare delivery system-related. Delay in seeking care was due to spiritual healers being first point of contact in addition to traditional and home remedies tried by mothers at home and inaccessible healthcare mostly owing to healthcare delivery system were some of the major barriers associated with case management of Neonatal Pneumonia. Conclusion This scoping review concludes that there is a paucity of studies on Neonatal Pneumonia in India particularly with respect to barriers to case management and that many of the barriers described here are applicable to a broad range of Neonatal disease conditions which occur in the community and not just specific to Neonatal Pneumonia.
Myron Anthony Godinho - One of the best experts on this subject based on the ideXlab platform.
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Factors associated with Neonatal Pneumonia in India: protocol for a systematic review and planned meta-analysis.
BMJ open, 2018Co-Authors: Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounts for more Neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of Pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of Pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on Neonatal Pneumonia in India. English language observational studies which report risk factors and determinants of Neonatal Pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using ‘Assessing the Methodological quality of Systematic Reviews’ and ‘Grades of Recommendation, Assessment, Development and Evaluation’. Ethics and dissemination The protocol of the entire project has been approved by the host institution’s ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the ‘Health Ministry Screening Committee’ under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.
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Risk factors and barriers to case management of Neonatal Pneumonia: protocol for a pan-India qualitative study of stakeholder perceptions
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounted for more Neonatal deaths (estimated at 696 000) than any other country, as of 2015. Of these , most Neonatal deaths due to infections can be attributed to Pneumonia which accounts for 16% of all Neonatal mortalities (2010). Despite simple, inexpensive case management strategies being available, Pneumonia continues to cause significant mortality and morbidity among neonates. Understanding the perceptions and experiences of stakeholders of Neonatal care can help find solutions to barriers to care and design tailored strategies for controlling Neonatal Pneumonia. Methods and analysis A pan-India qualitative study will be conducted. Participants include healthcare providers, programme officers, academicians, representatives of non-governmental organisations/bilateral agencies and policy makers. They will be recruited purposively from rural and urban, public and private, and facility and community healthcare settings across six Indian regions. Within each region, a minimum of one state will be selected. Districts will be based on Neonatal mortality indicators, and will be subject to feasibility at the time of conducting the study. We plan to conduct in-depth interviews (IDI) and focus group discussions focusing on (a) burden, (b) risk factors, (c) case management, (d) treatment guidelines, (e) barriers to case management, (f) recommendations. The number of interviews will depend on the information saturation. Interviews will be audio-recorded with prior written consent and transcribed verbatim. Principles of thematic analysis will be applied for qualitative data analysis using R package for Qualitative Data Analysis (RQDA). Ethics and dissemination The protocol has been approved by the Health Ministry Screening Committee, Government of India and the Institutional Ethics Committee at the host institution. Confidentiality and privacy of the participants will be maintained. The findings of the study will be shared with all stakeholders of this research including the participants. Knowledge dissemination workshops will be conducted to ultimately transfer the evidence tailored to the stakeholders9 need.
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Treatment options and barriers to case management of Neonatal Pneumonia in India: a protocol for a scoping review
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest Neonatal deaths globally. Case management is said to be the cornerstone of Pneumonia control. Much of the published evidence focuses on children aged 1 to 59 months. This scoping review, thus, aims to identify the treatment options for and barriers to case management of Neonatal Pneumonia in India. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Studies addressing treatment of or barriers to case management of Neonatal Pneumonia in Indian context, published in English in peer-reviewed and indexed journals will be eligible for inclusion. Electronic search will be conducted on nine databases. Hand searching and snowballing will be done for published and grey literature. Selection of studies will be done in title, abstract and full-text stages. A narrative summary will be performed to summarise the details of evidence. Ethics and dissemination As this is a review involving analysis of secondary data which is available in the public domain and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to ultimately transfer the evidence tailored to the stakeholder (eg, policy briefs, publications, information booklets and so on). PROSPERO 2016 CRD42016045449
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Factors associated with mortality due to Neonatal Pneumonia in India: a protocol for systematic review and planned meta-analysis
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest number of Neonatal deaths globally. It also has the greatest number of Pneumonia-related Neonatal deaths in the developing world. We aim to systematically review the evidence for the factors associated with mortality due to Neonatal Pneumonia in the Indian context, to address the lack of consolidated evidence on this important issue. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Observational studies reporting on outcome of Neonatal Pneumonia in the Indian context, and published in English in peer-reviewed and indexed journals will be eligible for inclusion. Outcomes of this review will be the factors determining mortality due to Neonatal Pneumonia. A total of nine databases will be searched. Electronic and hand searching of published and grey literature will be performed. Selection of studies will be done in title, abstract and full text screening stages. Risk of bias, independently assessed by two authors, will be evaluated. Meta-analysis will be performed and heterogeneity assessed. Pooled effect estimates will be stated with 95% confidence intervals. Narrative synthesis will be done where meta-analysis cannot be performed. Publication bias will be evaluated and sensitivity analysis performed according to study quality. Quality of this review will be evaluated using AMSTAR (Assessing the Methodological quality of Systematic Reviews) and GRADE (Grades of Recommendation, Assessment, Development & Evaluation). A summary of findings table will be reported using GRADEPro. Ethics and dissemination Since this is a review involving analysis of secondary data which is available in the public domain, and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to transfer the evidence, tailored to the stakeholder (eg, policy briefs, publications, information booklets, etc).
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A scoping review on barriers to case management of Neonatal Pneumonia in India
Clinical Epidemiology and Global Health, 1Co-Authors: N Sreekumaran Nair, Leslie Lewis, Vijay Shree Dhyani, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Prachi Pundir, Bhumika T VenkateshAbstract:Abstract Background Neonatal Pneumonia is one of the leading factors contributing to Neonatal mortality. The objective of this review was to identify the barriers associated with case management of Neonatal Pneumonia in India by conducting a scoping review. Methods Nine databases (PubMed, ProQuest, Ovid Medline, CINAHL, Web of Science, EMBASE, IndMED, SCOPUS and WHOLIS) were searched to identify relevant studies in India. The population of interest were neonates. Outcome of interest was barriers associated with case management of Neonatal Pneumonia. Data was charted and reported in accordance with the ‘guidance for conducting systematic scoping reviews'. Results From 5942 citations screened, 244 articles underwent full text screening and two studies with qualitative information met the eligibility criteria. Barriers were classified as patient-related, caregiver-related and healthcare delivery system-related. Delay in seeking care was due to spiritual healers being first point of contact in addition to traditional and home remedies tried by mothers at home and inaccessible healthcare mostly owing to healthcare delivery system were some of the major barriers associated with case management of Neonatal Pneumonia. Conclusion This scoping review concludes that there is a paucity of studies on Neonatal Pneumonia in India particularly with respect to barriers to case management and that many of the barriers described here are applicable to a broad range of Neonatal disease conditions which occur in the community and not just specific to Neonatal Pneumonia.
Leslie Lewis - One of the best experts on this subject based on the ideXlab platform.
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Factors associated with Neonatal Pneumonia in India: protocol for a systematic review and planned meta-analysis.
BMJ open, 2018Co-Authors: Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounts for more Neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of Pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of Pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on Neonatal Pneumonia in India. English language observational studies which report risk factors and determinants of Neonatal Pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using ‘Assessing the Methodological quality of Systematic Reviews’ and ‘Grades of Recommendation, Assessment, Development and Evaluation’. Ethics and dissemination The protocol of the entire project has been approved by the host institution’s ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the ‘Health Ministry Screening Committee’ under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.
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Risk factors and barriers to case management of Neonatal Pneumonia: protocol for a pan-India qualitative study of stakeholder perceptions
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounted for more Neonatal deaths (estimated at 696 000) than any other country, as of 2015. Of these , most Neonatal deaths due to infections can be attributed to Pneumonia which accounts for 16% of all Neonatal mortalities (2010). Despite simple, inexpensive case management strategies being available, Pneumonia continues to cause significant mortality and morbidity among neonates. Understanding the perceptions and experiences of stakeholders of Neonatal care can help find solutions to barriers to care and design tailored strategies for controlling Neonatal Pneumonia. Methods and analysis A pan-India qualitative study will be conducted. Participants include healthcare providers, programme officers, academicians, representatives of non-governmental organisations/bilateral agencies and policy makers. They will be recruited purposively from rural and urban, public and private, and facility and community healthcare settings across six Indian regions. Within each region, a minimum of one state will be selected. Districts will be based on Neonatal mortality indicators, and will be subject to feasibility at the time of conducting the study. We plan to conduct in-depth interviews (IDI) and focus group discussions focusing on (a) burden, (b) risk factors, (c) case management, (d) treatment guidelines, (e) barriers to case management, (f) recommendations. The number of interviews will depend on the information saturation. Interviews will be audio-recorded with prior written consent and transcribed verbatim. Principles of thematic analysis will be applied for qualitative data analysis using R package for Qualitative Data Analysis (RQDA). Ethics and dissemination The protocol has been approved by the Health Ministry Screening Committee, Government of India and the Institutional Ethics Committee at the host institution. Confidentiality and privacy of the participants will be maintained. The findings of the study will be shared with all stakeholders of this research including the participants. Knowledge dissemination workshops will be conducted to ultimately transfer the evidence tailored to the stakeholders9 need.
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Treatment options and barriers to case management of Neonatal Pneumonia in India: a protocol for a scoping review
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest Neonatal deaths globally. Case management is said to be the cornerstone of Pneumonia control. Much of the published evidence focuses on children aged 1 to 59 months. This scoping review, thus, aims to identify the treatment options for and barriers to case management of Neonatal Pneumonia in India. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Studies addressing treatment of or barriers to case management of Neonatal Pneumonia in Indian context, published in English in peer-reviewed and indexed journals will be eligible for inclusion. Electronic search will be conducted on nine databases. Hand searching and snowballing will be done for published and grey literature. Selection of studies will be done in title, abstract and full-text stages. A narrative summary will be performed to summarise the details of evidence. Ethics and dissemination As this is a review involving analysis of secondary data which is available in the public domain and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to ultimately transfer the evidence tailored to the stakeholder (eg, policy briefs, publications, information booklets and so on). PROSPERO 2016 CRD42016045449
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Factors associated with mortality due to Neonatal Pneumonia in India: a protocol for systematic review and planned meta-analysis
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest number of Neonatal deaths globally. It also has the greatest number of Pneumonia-related Neonatal deaths in the developing world. We aim to systematically review the evidence for the factors associated with mortality due to Neonatal Pneumonia in the Indian context, to address the lack of consolidated evidence on this important issue. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Observational studies reporting on outcome of Neonatal Pneumonia in the Indian context, and published in English in peer-reviewed and indexed journals will be eligible for inclusion. Outcomes of this review will be the factors determining mortality due to Neonatal Pneumonia. A total of nine databases will be searched. Electronic and hand searching of published and grey literature will be performed. Selection of studies will be done in title, abstract and full text screening stages. Risk of bias, independently assessed by two authors, will be evaluated. Meta-analysis will be performed and heterogeneity assessed. Pooled effect estimates will be stated with 95% confidence intervals. Narrative synthesis will be done where meta-analysis cannot be performed. Publication bias will be evaluated and sensitivity analysis performed according to study quality. Quality of this review will be evaluated using AMSTAR (Assessing the Methodological quality of Systematic Reviews) and GRADE (Grades of Recommendation, Assessment, Development & Evaluation). A summary of findings table will be reported using GRADEPro. Ethics and dissemination Since this is a review involving analysis of secondary data which is available in the public domain, and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to transfer the evidence, tailored to the stakeholder (eg, policy briefs, publications, information booklets, etc).
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A scoping review on barriers to case management of Neonatal Pneumonia in India
Clinical Epidemiology and Global Health, 1Co-Authors: N Sreekumaran Nair, Leslie Lewis, Vijay Shree Dhyani, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Prachi Pundir, Bhumika T VenkateshAbstract:Abstract Background Neonatal Pneumonia is one of the leading factors contributing to Neonatal mortality. The objective of this review was to identify the barriers associated with case management of Neonatal Pneumonia in India by conducting a scoping review. Methods Nine databases (PubMed, ProQuest, Ovid Medline, CINAHL, Web of Science, EMBASE, IndMED, SCOPUS and WHOLIS) were searched to identify relevant studies in India. The population of interest were neonates. Outcome of interest was barriers associated with case management of Neonatal Pneumonia. Data was charted and reported in accordance with the ‘guidance for conducting systematic scoping reviews'. Results From 5942 citations screened, 244 articles underwent full text screening and two studies with qualitative information met the eligibility criteria. Barriers were classified as patient-related, caregiver-related and healthcare delivery system-related. Delay in seeking care was due to spiritual healers being first point of contact in addition to traditional and home remedies tried by mothers at home and inaccessible healthcare mostly owing to healthcare delivery system were some of the major barriers associated with case management of Neonatal Pneumonia. Conclusion This scoping review concludes that there is a paucity of studies on Neonatal Pneumonia in India particularly with respect to barriers to case management and that many of the barriers described here are applicable to a broad range of Neonatal disease conditions which occur in the community and not just specific to Neonatal Pneumonia.
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Factors associated with Neonatal Pneumonia in India: protocol for a systematic review and planned meta-analysis.
BMJ open, 2018Co-Authors: Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounts for more Neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of Pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of Pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on Neonatal Pneumonia in India. English language observational studies which report risk factors and determinants of Neonatal Pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using ‘Assessing the Methodological quality of Systematic Reviews’ and ‘Grades of Recommendation, Assessment, Development and Evaluation’. Ethics and dissemination The protocol of the entire project has been approved by the host institution’s ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the ‘Health Ministry Screening Committee’ under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.
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Risk factors and barriers to case management of Neonatal Pneumonia: protocol for a pan-India qualitative study of stakeholder perceptions
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India accounted for more Neonatal deaths (estimated at 696 000) than any other country, as of 2015. Of these , most Neonatal deaths due to infections can be attributed to Pneumonia which accounts for 16% of all Neonatal mortalities (2010). Despite simple, inexpensive case management strategies being available, Pneumonia continues to cause significant mortality and morbidity among neonates. Understanding the perceptions and experiences of stakeholders of Neonatal care can help find solutions to barriers to care and design tailored strategies for controlling Neonatal Pneumonia. Methods and analysis A pan-India qualitative study will be conducted. Participants include healthcare providers, programme officers, academicians, representatives of non-governmental organisations/bilateral agencies and policy makers. They will be recruited purposively from rural and urban, public and private, and facility and community healthcare settings across six Indian regions. Within each region, a minimum of one state will be selected. Districts will be based on Neonatal mortality indicators, and will be subject to feasibility at the time of conducting the study. We plan to conduct in-depth interviews (IDI) and focus group discussions focusing on (a) burden, (b) risk factors, (c) case management, (d) treatment guidelines, (e) barriers to case management, (f) recommendations. The number of interviews will depend on the information saturation. Interviews will be audio-recorded with prior written consent and transcribed verbatim. Principles of thematic analysis will be applied for qualitative data analysis using R package for Qualitative Data Analysis (RQDA). Ethics and dissemination The protocol has been approved by the Health Ministry Screening Committee, Government of India and the Institutional Ethics Committee at the host institution. Confidentiality and privacy of the participants will be maintained. The findings of the study will be shared with all stakeholders of this research including the participants. Knowledge dissemination workshops will be conducted to ultimately transfer the evidence tailored to the stakeholders9 need.
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Treatment options and barriers to case management of Neonatal Pneumonia in India: a protocol for a scoping review
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest Neonatal deaths globally. Case management is said to be the cornerstone of Pneumonia control. Much of the published evidence focuses on children aged 1 to 59 months. This scoping review, thus, aims to identify the treatment options for and barriers to case management of Neonatal Pneumonia in India. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Studies addressing treatment of or barriers to case management of Neonatal Pneumonia in Indian context, published in English in peer-reviewed and indexed journals will be eligible for inclusion. Electronic search will be conducted on nine databases. Hand searching and snowballing will be done for published and grey literature. Selection of studies will be done in title, abstract and full-text stages. A narrative summary will be performed to summarise the details of evidence. Ethics and dissemination As this is a review involving analysis of secondary data which is available in the public domain and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to ultimately transfer the evidence tailored to the stakeholder (eg, policy briefs, publications, information booklets and so on). PROSPERO 2016 CRD42016045449
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Factors associated with mortality due to Neonatal Pneumonia in India: a protocol for systematic review and planned meta-analysis
BMJ open, 2017Co-Authors: N Sreekumaran Nair, Leslie Lewis, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Bhumika T VenkateshAbstract:Introduction India contributes to the highest number of Neonatal deaths globally. It also has the greatest number of Pneumonia-related Neonatal deaths in the developing world. We aim to systematically review the evidence for the factors associated with mortality due to Neonatal Pneumonia in the Indian context, to address the lack of consolidated evidence on this important issue. Methods and analysis This protocol is part of a series of three reviews on Neonatal Pneumonia in India. Observational studies reporting on outcome of Neonatal Pneumonia in the Indian context, and published in English in peer-reviewed and indexed journals will be eligible for inclusion. Outcomes of this review will be the factors determining mortality due to Neonatal Pneumonia. A total of nine databases will be searched. Electronic and hand searching of published and grey literature will be performed. Selection of studies will be done in title, abstract and full text screening stages. Risk of bias, independently assessed by two authors, will be evaluated. Meta-analysis will be performed and heterogeneity assessed. Pooled effect estimates will be stated with 95% confidence intervals. Narrative synthesis will be done where meta-analysis cannot be performed. Publication bias will be evaluated and sensitivity analysis performed according to study quality. Quality of this review will be evaluated using AMSTAR (Assessing the Methodological quality of Systematic Reviews) and GRADE (Grades of Recommendation, Assessment, Development & Evaluation). A summary of findings table will be reported using GRADEPro. Ethics and dissemination Since this is a review involving analysis of secondary data which is available in the public domain, and does not involve human participants, ethical approval was not required. The findings of the study will be shared with all stakeholders of this research. Knowledge dissemination workshops will be conducted with relevant stakeholders to transfer the evidence, tailored to the stakeholder (eg, policy briefs, publications, information booklets, etc).
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A scoping review on barriers to case management of Neonatal Pneumonia in India
Clinical Epidemiology and Global Health, 1Co-Authors: N Sreekumaran Nair, Leslie Lewis, Vijay Shree Dhyani, Shruti Murthy, Myron Anthony Godinho, Theophilus Lakiang, Prachi Pundir, Bhumika T VenkateshAbstract:Abstract Background Neonatal Pneumonia is one of the leading factors contributing to Neonatal mortality. The objective of this review was to identify the barriers associated with case management of Neonatal Pneumonia in India by conducting a scoping review. Methods Nine databases (PubMed, ProQuest, Ovid Medline, CINAHL, Web of Science, EMBASE, IndMED, SCOPUS and WHOLIS) were searched to identify relevant studies in India. The population of interest were neonates. Outcome of interest was barriers associated with case management of Neonatal Pneumonia. Data was charted and reported in accordance with the ‘guidance for conducting systematic scoping reviews'. Results From 5942 citations screened, 244 articles underwent full text screening and two studies with qualitative information met the eligibility criteria. Barriers were classified as patient-related, caregiver-related and healthcare delivery system-related. Delay in seeking care was due to spiritual healers being first point of contact in addition to traditional and home remedies tried by mothers at home and inaccessible healthcare mostly owing to healthcare delivery system were some of the major barriers associated with case management of Neonatal Pneumonia. Conclusion This scoping review concludes that there is a paucity of studies on Neonatal Pneumonia in India particularly with respect to barriers to case management and that many of the barriers described here are applicable to a broad range of Neonatal disease conditions which occur in the community and not just specific to Neonatal Pneumonia.
