Nerve Lesion

14,000,000 Leading Edge Experts on the ideXlab platform

Scan Science and Technology

Contact Leading Edge Experts & Companies

Scan Science and Technology

Contact Leading Edge Experts & Companies

The Experts below are selected from a list of 303 Experts worldwide ranked by ideXlab platform

Yeliz Terzi - One of the best experts on this subject based on the ideXlab platform.

  • winged scapula caused by a dorsal scapular Nerve Lesion a case report
    Archives of Physical Medicine and Rehabilitation, 2008
    Co-Authors: Kenan Akgun, Ilknur Aktas, Yeliz Terzi
    Abstract:

    Akgun K, Aktas I, Terzi Y. Winged scapula caused by a dorsal scapular Nerve Lesion: a case report. Arch Phys Med Rehabil 2008;89:2017-20. Dorsal scapular Nerve Lesions are quite rare. A case of a 51-year-old man who had right shoulder pain, weakness of right arm elevation, and prominence of right scapula for 6 months is presented. The condition had been abruptly devel- oped after lifting a heavy box overhead on which he felt a sharp pain in the right shoulder. On clinical examination, there was a prominence of the lower medial border and inferior angle of the right scapula compared with the left. In addition, the right scapula was located more lateral. Magnetic resonance imaging of the thorax revealed the presence of a thinner rhomboid major muscle with a pathologic signal compared with the other side. Needle electromyography of the right rhomboid muscle re- vealed a long duration, polyphasic motor unit potential with reinnervation potentials, and spontaneous activity. According to these findings, the patient was diagnosed as having a winged scapula because of dorsal scapular Nerve Lesion.

  • Winged Scapula Caused by a Dorsal Scapular Nerve Lesion: A Case Report
    Archives of physical medicine and rehabilitation, 2008
    Co-Authors: Kenan Akgun, Ilknur Aktas, Yeliz Terzi
    Abstract:

    Dorsal scapular Nerve Lesions are quite rare. A case of a 51-year-old man who had right shoulder pain, weakness of right arm elevation, and prominence of right scapula for 6 months is presented. The condition had been abruptly developed after lifting a heavy box overhead on which he felt a sharp pain in the right shoulder. On clinical examination, there was a prominence of the lower medial border and inferior angle of the right scapula compared with the left. In addition, the right scapula was located more lateral. Magnetic resonance imaging of the thorax revealed the presence of a thinner rhomboid major muscle with a pathologic signal compared with the other side. Needle electromyography of the right rhomboid muscle revealed a long duration, polyphasic motor unit potential with reinnervation potentials, and spontaneous activity. According to these findings, the patient was diagnosed as having a winged scapula because of dorsal scapular Nerve Lesion.

Kenan Akgun - One of the best experts on this subject based on the ideXlab platform.

  • winged scapula caused by a dorsal scapular Nerve Lesion a case report
    Archives of Physical Medicine and Rehabilitation, 2008
    Co-Authors: Kenan Akgun, Ilknur Aktas, Yeliz Terzi
    Abstract:

    Akgun K, Aktas I, Terzi Y. Winged scapula caused by a dorsal scapular Nerve Lesion: a case report. Arch Phys Med Rehabil 2008;89:2017-20. Dorsal scapular Nerve Lesions are quite rare. A case of a 51-year-old man who had right shoulder pain, weakness of right arm elevation, and prominence of right scapula for 6 months is presented. The condition had been abruptly devel- oped after lifting a heavy box overhead on which he felt a sharp pain in the right shoulder. On clinical examination, there was a prominence of the lower medial border and inferior angle of the right scapula compared with the left. In addition, the right scapula was located more lateral. Magnetic resonance imaging of the thorax revealed the presence of a thinner rhomboid major muscle with a pathologic signal compared with the other side. Needle electromyography of the right rhomboid muscle re- vealed a long duration, polyphasic motor unit potential with reinnervation potentials, and spontaneous activity. According to these findings, the patient was diagnosed as having a winged scapula because of dorsal scapular Nerve Lesion.

  • Winged Scapula Caused by a Dorsal Scapular Nerve Lesion: A Case Report
    Archives of physical medicine and rehabilitation, 2008
    Co-Authors: Kenan Akgun, Ilknur Aktas, Yeliz Terzi
    Abstract:

    Dorsal scapular Nerve Lesions are quite rare. A case of a 51-year-old man who had right shoulder pain, weakness of right arm elevation, and prominence of right scapula for 6 months is presented. The condition had been abruptly developed after lifting a heavy box overhead on which he felt a sharp pain in the right shoulder. On clinical examination, there was a prominence of the lower medial border and inferior angle of the right scapula compared with the left. In addition, the right scapula was located more lateral. Magnetic resonance imaging of the thorax revealed the presence of a thinner rhomboid major muscle with a pathologic signal compared with the other side. Needle electromyography of the right rhomboid muscle revealed a long duration, polyphasic motor unit potential with reinnervation potentials, and spontaneous activity. According to these findings, the patient was diagnosed as having a winged scapula because of dorsal scapular Nerve Lesion.

Roland Nau - One of the best experts on this subject based on the ideXlab platform.

W Janig - One of the best experts on this subject based on the ideXlab platform.

  • ectopic activity in cutaneous regenerating afferent Nerve fibers following Nerve Lesion in the rat
    European Journal of Neuroscience, 2003
    Co-Authors: Natalia Gorodetskaya, Cristina Constantin, W Janig
    Abstract:

    Spontaneous activity, and mechanical and thermal sensitivity were investigated in regenerating afferent Nerve fibers within 4-21 days post sural Nerve Lesion (crush or transection and resuturing) in anaesthetized rats. About 33-40% of the myelinated (A) and 22-27% of the unmyelinated (C) fibers excited by electrical Nerve stimulation exhibited at least one of these ectopic discharge properties. In total 177 A- and 169 C-fibers with ectopic activity were analysed. Most A-fibers (161/177) were mechanosensitive. Spontaneous activity (median 1 imp/s) was present in 23/177 and thermosensitivity in 14/177 A-fibers (13 of them being activated by heat stimuli). Almost all A-fibers (159/177) exhibited only one type of ectopic discharge property. Most C-fibers (94/169) were thermosensitive responding either to cold (n = 45) or to heat stimuli (n = 33) or to both (n = 16). Eighty-four of 169 C-fibers were spontaneously active (median 0.3 imp/s) and 75/169 C-fibers were mechanosensitive. Both the proportion and the discharge rate of spontaneously active C-fibers were significantly higher after crush than after section and resuturing of the Nerve. About 60% of the C-fibers (101/169) had only one ectopic discharge property and 40% two or three. In conclusion, regenerating cutaneous afferent A- and C-fibers may develop mechano- and/or thermosensitivity as well as spontaneous activity. We suggest that spontaneous and evoked ectopic activity in regenerating cutaneous afferents are a function of the intrinsic functional properties of these neurons and of the interaction between the regenerating Nerve fibers and non-neural cells during Wallerian degeneration in the Nerve distal to the Nerve Lesion.

  • sympathetic sensory coupling after l5 spinal Nerve Lesion in the rat and its relation to changes in dorsal root ganglion blood flow
    Pain, 2000
    Co-Authors: Heinz-joachim Häbler, Sebastian Eschenfelder, Xianguo Liu, W Janig
    Abstract:

    Abstract Transection of the L5 spinal Nerve in rats results in allodynia- and hyperalgesia-like behavior to mechanical stimulation which are thought to be mediated by ectopic activity arising in Lesioned afferent neurons mainly in the dorsal root ganglion (DRG). It has been suggested that the neuropathic pain behavior is dependent on the sympathetic nervous system. In rats 3–56 days after L5 spinal Nerve Lesion, we tested responses of axotomized afferent fibers recorded in the dorsal root of the Lesioned segment to norepinephrine (NE, 0.5 μg/kg) injected intravenously and to selective electrical stimulation of the lumbar sympathetic trunk (LST). In some experiments we measured blood flow in the DRG by laser Doppler flowmetry. The majority of Lesioned afferent fibers with spontaneous activity responded to neither LST stimulation (82.4%) nor NE (71.4%). In those which did react to LST stimulation, responses occurred only at high stimulation frequencies (likely to be above the physiological range), and they could be mimicked by non-adrenergic vasoconstrictor drugs (angiotensin II, vasopressin). Excitatory responses to LST stimulation were closely correlated with the stimulation-induced phasic vasoconstrictions in the DRG. We therefore hypothesized that the activation of Lesioned afferents might be brought about indirectly by an impaired blood supply to the DRG. To test this hypothesis we induced a strong and sustained baseline vasoconstriction in the DRG by blocking endothelial nitric oxide synthesis with NG-nitro- l -arginine methyl ester ( l -NAME) applied systemically. l -NAME enhanced baseline vascular resistance in the DRG about threefold and also increased stimulation-induced vasoconstrictions. After l -NAME, the majority of axotomized neurons with spontaneous activity were activated by LST stimulation (76%) or NE (75%). Again, activations closely followed stimulation-induced phasic vasoconstrictions in the DRG provided that a critical level of vasoconstriction was exceeded. In the present study, inhibitory responses to LST stimulation were generally rare and could be reversed to activation by prolonged stimulation or after l -NAME. These results show that sympathetic-sensory coupling occurs only in a minority of axotomized afferents after L5 spinal Nerve injury. Like previous studies, they cast doubt on the notion that the L5 spinal Nerve Lesion is a good model for sympathetically maintained pain. Since responses of Lesioned afferent neurons to LST stimulation and NE could be provoked with high reliability after inducing vasoconstriction in the DRG, and since they mirrored stimulation-induced vasoconstrictions in the DRG, it appears that in this model the association of sympathetic activity with afferent discharge occurs mainly when perfusion of the DRG is impaired.

  • dorsal root section elicits signs of neuropathic pain rather than reversing them in rats with l5 spinal Nerve injury
    Pain, 2000
    Co-Authors: Sebastian Eschenfelder, Heinz-joachim Häbler, W Janig
    Abstract:

    Mechanical allodynia- and hyperalgesia-like behavior which develops in rats after L5 spinal Nerve Lesion has been suggested to be due to ectopic activity in the Lesioned afferent neurons originating at the Lesion site and/or in the dorsal root ganglion because it is eliminated by section of the dorsal root. Here we reevaluated the effect of a dorsal rhizotomy in rats after L5 spinal Nerve Lesion. Using calibrated von Frey hairs, paw withdrawal threshold to single stimuli and paw withdrawal incidence to repetitive stimulation were tested before and after Nerve section. Neuropathic pain behavior of similar time course and magnitude also developed after cutting the L5 dorsal root, and L5 spinal Nerve Lesion-induced abnormal behavior could not be reversed by dorsal rhizotomy. The neuropathic pain behavior elicited by dorsal root section also developed when impulse conduction in the dorsal root axons was blocked during rhizotomy by a local anesthetic, i.e. when the immediate injury discharge was prevented from reaching the spinal cord. These results challenge the widely accepted idea that neuropathic pain behavior developing after spinal Nerve Lesion is dependent on ectopic activity in the Lesioned afferent neurons. However, the present results do not rule out the possibility that after the two Nerve Lesions the mechanisms generating neuropathic pain behavior are different. After dorsal rhizotomy neuropathic pain behavior may be related to deafferentation whereas after spinal Nerve Lesion it may be caused by ectopic activity.

Ilknur Aktas - One of the best experts on this subject based on the ideXlab platform.

  • winged scapula caused by a dorsal scapular Nerve Lesion a case report
    Archives of Physical Medicine and Rehabilitation, 2008
    Co-Authors: Kenan Akgun, Ilknur Aktas, Yeliz Terzi
    Abstract:

    Akgun K, Aktas I, Terzi Y. Winged scapula caused by a dorsal scapular Nerve Lesion: a case report. Arch Phys Med Rehabil 2008;89:2017-20. Dorsal scapular Nerve Lesions are quite rare. A case of a 51-year-old man who had right shoulder pain, weakness of right arm elevation, and prominence of right scapula for 6 months is presented. The condition had been abruptly devel- oped after lifting a heavy box overhead on which he felt a sharp pain in the right shoulder. On clinical examination, there was a prominence of the lower medial border and inferior angle of the right scapula compared with the left. In addition, the right scapula was located more lateral. Magnetic resonance imaging of the thorax revealed the presence of a thinner rhomboid major muscle with a pathologic signal compared with the other side. Needle electromyography of the right rhomboid muscle re- vealed a long duration, polyphasic motor unit potential with reinnervation potentials, and spontaneous activity. According to these findings, the patient was diagnosed as having a winged scapula because of dorsal scapular Nerve Lesion.

  • Winged Scapula Caused by a Dorsal Scapular Nerve Lesion: A Case Report
    Archives of physical medicine and rehabilitation, 2008
    Co-Authors: Kenan Akgun, Ilknur Aktas, Yeliz Terzi
    Abstract:

    Dorsal scapular Nerve Lesions are quite rare. A case of a 51-year-old man who had right shoulder pain, weakness of right arm elevation, and prominence of right scapula for 6 months is presented. The condition had been abruptly developed after lifting a heavy box overhead on which he felt a sharp pain in the right shoulder. On clinical examination, there was a prominence of the lower medial border and inferior angle of the right scapula compared with the left. In addition, the right scapula was located more lateral. Magnetic resonance imaging of the thorax revealed the presence of a thinner rhomboid major muscle with a pathologic signal compared with the other side. Needle electromyography of the right rhomboid muscle revealed a long duration, polyphasic motor unit potential with reinnervation potentials, and spontaneous activity. According to these findings, the patient was diagnosed as having a winged scapula because of dorsal scapular Nerve Lesion.