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Dong Won Kim - One of the best experts on this subject based on the ideXlab platform.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway
    Clinical Neuroradiology, 2020
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography. Methods Diffusion-tensor tractography imaging was performed using a 3T magnetic resonance imaging system to evaluate structural alterations in the auditory Neural Pathway of patients with unilateral sensoriNeural hearing loss. The two diffusion-tensor tractography parameters, fractional anisotropy and the apparent diffusion coefficient were compared between the ipsilateral side and the contralateral side in patients and controls. Additionally, correlations between the parameter values and the hearing loss level in patients were evaluated. Results A total of 24 sensoriNeural hearing loss patients (14 males; age range, 17–65 years; average age, 45.3 years) and 24 age and sex-matched control subjects were enrolled. Fractional anisotropy values on the ipsilateral and contralateral sides were significantly lower in patients than in the control group ( p  = 0.004 and 0.001, respectively). The differences in the apparent diffusion coefficient values for the ipsilateral and contralateral sides between the two groups were not significant ( p  = 0.279 and 0.248, respectively). There was an inverse relationship between fractional anisotropy and the severity of hearing impairment on the ipsilateral and contralateral sides (r = −0.519, p  = 0.005 and r = −0.454, p  = 0.015, respectively). No significant correlation was found between the apparent diffusion coefficient and hearing loss level on the ipsilateral and contralateral sides (r = 0.172, p  = 0.380 and r = 0.131, p  = 0.508, respectively). Conclusion Quantitative diffusion-tensor tractography can be used to detect microstructural alterations in the auditory Neural Pathway in sensoriNeural hearing loss patients with normal results in standard imaging studies.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway : Clinical Usefulness in Patients with Unilateral SensoriNeural Hearing Loss.
    Clinical neuroradiology, 2018
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography.

Sanghyeon Kim - One of the best experts on this subject based on the ideXlab platform.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway
    Clinical Neuroradiology, 2020
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography. Methods Diffusion-tensor tractography imaging was performed using a 3T magnetic resonance imaging system to evaluate structural alterations in the auditory Neural Pathway of patients with unilateral sensoriNeural hearing loss. The two diffusion-tensor tractography parameters, fractional anisotropy and the apparent diffusion coefficient were compared between the ipsilateral side and the contralateral side in patients and controls. Additionally, correlations between the parameter values and the hearing loss level in patients were evaluated. Results A total of 24 sensoriNeural hearing loss patients (14 males; age range, 17–65 years; average age, 45.3 years) and 24 age and sex-matched control subjects were enrolled. Fractional anisotropy values on the ipsilateral and contralateral sides were significantly lower in patients than in the control group ( p  = 0.004 and 0.001, respectively). The differences in the apparent diffusion coefficient values for the ipsilateral and contralateral sides between the two groups were not significant ( p  = 0.279 and 0.248, respectively). There was an inverse relationship between fractional anisotropy and the severity of hearing impairment on the ipsilateral and contralateral sides (r = −0.519, p  = 0.005 and r = −0.454, p  = 0.015, respectively). No significant correlation was found between the apparent diffusion coefficient and hearing loss level on the ipsilateral and contralateral sides (r = 0.172, p  = 0.380 and r = 0.131, p  = 0.508, respectively). Conclusion Quantitative diffusion-tensor tractography can be used to detect microstructural alterations in the auditory Neural Pathway in sensoriNeural hearing loss patients with normal results in standard imaging studies.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway : Clinical Usefulness in Patients with Unilateral SensoriNeural Hearing Loss.
    Clinical neuroradiology, 2018
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography.

Hee Jin Kwon - One of the best experts on this subject based on the ideXlab platform.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway
    Clinical Neuroradiology, 2020
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography. Methods Diffusion-tensor tractography imaging was performed using a 3T magnetic resonance imaging system to evaluate structural alterations in the auditory Neural Pathway of patients with unilateral sensoriNeural hearing loss. The two diffusion-tensor tractography parameters, fractional anisotropy and the apparent diffusion coefficient were compared between the ipsilateral side and the contralateral side in patients and controls. Additionally, correlations between the parameter values and the hearing loss level in patients were evaluated. Results A total of 24 sensoriNeural hearing loss patients (14 males; age range, 17–65 years; average age, 45.3 years) and 24 age and sex-matched control subjects were enrolled. Fractional anisotropy values on the ipsilateral and contralateral sides were significantly lower in patients than in the control group ( p  = 0.004 and 0.001, respectively). The differences in the apparent diffusion coefficient values for the ipsilateral and contralateral sides between the two groups were not significant ( p  = 0.279 and 0.248, respectively). There was an inverse relationship between fractional anisotropy and the severity of hearing impairment on the ipsilateral and contralateral sides (r = −0.519, p  = 0.005 and r = −0.454, p  = 0.015, respectively). No significant correlation was found between the apparent diffusion coefficient and hearing loss level on the ipsilateral and contralateral sides (r = 0.172, p  = 0.380 and r = 0.131, p  = 0.508, respectively). Conclusion Quantitative diffusion-tensor tractography can be used to detect microstructural alterations in the auditory Neural Pathway in sensoriNeural hearing loss patients with normal results in standard imaging studies.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway : Clinical Usefulness in Patients with Unilateral SensoriNeural Hearing Loss.
    Clinical neuroradiology, 2018
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography.

Eun-ju Kang - One of the best experts on this subject based on the ideXlab platform.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway
    Clinical Neuroradiology, 2020
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography. Methods Diffusion-tensor tractography imaging was performed using a 3T magnetic resonance imaging system to evaluate structural alterations in the auditory Neural Pathway of patients with unilateral sensoriNeural hearing loss. The two diffusion-tensor tractography parameters, fractional anisotropy and the apparent diffusion coefficient were compared between the ipsilateral side and the contralateral side in patients and controls. Additionally, correlations between the parameter values and the hearing loss level in patients were evaluated. Results A total of 24 sensoriNeural hearing loss patients (14 males; age range, 17–65 years; average age, 45.3 years) and 24 age and sex-matched control subjects were enrolled. Fractional anisotropy values on the ipsilateral and contralateral sides were significantly lower in patients than in the control group ( p  = 0.004 and 0.001, respectively). The differences in the apparent diffusion coefficient values for the ipsilateral and contralateral sides between the two groups were not significant ( p  = 0.279 and 0.248, respectively). There was an inverse relationship between fractional anisotropy and the severity of hearing impairment on the ipsilateral and contralateral sides (r = −0.519, p  = 0.005 and r = −0.454, p  = 0.015, respectively). No significant correlation was found between the apparent diffusion coefficient and hearing loss level on the ipsilateral and contralateral sides (r = 0.172, p  = 0.380 and r = 0.131, p  = 0.508, respectively). Conclusion Quantitative diffusion-tensor tractography can be used to detect microstructural alterations in the auditory Neural Pathway in sensoriNeural hearing loss patients with normal results in standard imaging studies.

  • Diffusion-Tensor Tractography of the Auditory Neural Pathway : Clinical Usefulness in Patients with Unilateral SensoriNeural Hearing Loss.
    Clinical neuroradiology, 2018
    Co-Authors: Sanghyeon Kim, Hee Jin Kwon, Eun-ju Kang, Dong Won Kim
    Abstract:

    Purpose The purpose of this study was to evaluate the structural integrity of the auditory Neural Pathway in patients with unilateral sensoriNeural hearing loss using quantitative diffusion-tensor tractography.

Rogier B Mars - One of the best experts on this subject based on the ideXlab platform.

  • causal manipulation of functional connectivity in a specific Neural Pathway during behaviour and at rest
    eLife, 2015
    Co-Authors: Vanessa M Johnen, Franzxaver Neubert, Ethan R Buch, Lennart Verhagen, Jill X Oreilly, Rogier B Mars
    Abstract:

    Correlations in brain activity between two areas (functional connectivity) have been shown to relate to their underlying structural connections. We examine the possibility that functional connectivity also reflects short-term changes in synaptic efficacy. We demonstrate that paired transcranial magnetic stimulation (TMS) near ventral premotor cortex (PMv) and primary motor cortex (M1) with a short 8-ms inter-pulse interval evoking synchronous pre- and post-synaptic activity and which strengthens interregional connectivity between the two areas in a pattern consistent with Hebbian plasticity, leads to increased functional connectivity between PMv and M1 as measured with functional magnetic resonance imaging (fMRI). Moreover, we show that strengthening connectivity between these nodes has effects on a wider network of areas, such as decreasing coupling in a parallel motor programming stream. A control experiment revealed that identical TMS pulses at identical frequencies caused no change in fMRI-measured functional connectivity when the inter-pulse-interval was too long for Hebbian-like plasticity.