The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform
Swaminathan Sethuraman - One of the best experts on this subject based on the ideXlab platform.
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development of biomaterial scaffold for nerve tissue engineering biomaterial mediated Neural regeneration
Journal of Biomedical Science, 2009Co-Authors: Anuradha Subramanian, Uma Maheswari Krishnan, Swaminathan SethuramanAbstract:Neural tissue repair and regeneration strategies have received a great deal of attention because it directly affects the quality of the patient's life. There are many scientific challenges to regenerate nerve while using conventional autologous nerve grafts and from the newly developed therapeutic strategies for the reconstruction of damaged nerves. Recent advancements in nerve regeneration have involved the application of tissue engineering principles and this has evolved a new perspective to Neural Therapy. The success of Neural tissue engineering is mainly based on the regulation of cell behavior and tissue progression through the development of a synthetic scaffold that is analogous to the natural extracellular matrix and can support three-dimensional cell cultures. As the natural extracellular matrix provides an ideal environment for topographical, electrical and chemical cues to the adhesion and proliferation of Neural cells, there exists a need to develop a synthetic scaffold that would be biocompatible, immunologically inert, conducting, biodegradable, and infection-resistant biomaterial to support neurite outgrowth. This review outlines the rationale for effective Neural tissue engineering through the use of suitable biomaterials and scaffolding techniques for fabrication of a construct that would allow the neurons to adhere, proliferate and eventually form nerves.
Anuradha Subramanian - One of the best experts on this subject based on the ideXlab platform.
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development of biomaterial scaffold for nerve tissue engineering biomaterial mediated Neural regeneration
Journal of Biomedical Science, 2009Co-Authors: Anuradha Subramanian, Uma Maheswari Krishnan, Swaminathan SethuramanAbstract:Neural tissue repair and regeneration strategies have received a great deal of attention because it directly affects the quality of the patient's life. There are many scientific challenges to regenerate nerve while using conventional autologous nerve grafts and from the newly developed therapeutic strategies for the reconstruction of damaged nerves. Recent advancements in nerve regeneration have involved the application of tissue engineering principles and this has evolved a new perspective to Neural Therapy. The success of Neural tissue engineering is mainly based on the regulation of cell behavior and tissue progression through the development of a synthetic scaffold that is analogous to the natural extracellular matrix and can support three-dimensional cell cultures. As the natural extracellular matrix provides an ideal environment for topographical, electrical and chemical cues to the adhesion and proliferation of Neural cells, there exists a need to develop a synthetic scaffold that would be biocompatible, immunologically inert, conducting, biodegradable, and infection-resistant biomaterial to support neurite outgrowth. This review outlines the rationale for effective Neural tissue engineering through the use of suitable biomaterials and scaffolding techniques for fabrication of a construct that would allow the neurons to adhere, proliferate and eventually form nerves.
Maria Luisa Cárdenas - One of the best experts on this subject based on the ideXlab platform.
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PROCAINE, EPIGENETICS AND Neural Therapy, ¿A therapeutic alternative?
2011Co-Authors: Juan Carlos Jiménez Illera, Maria Luisa CárdenasAbstract:SUMMARY Procaine, epigenetics and Neural Therapy, ?a therapeutic alternative? A hallmark of human cancer from epigenetics is the silencing of tumor suppressor genes, along with DNA hypermethylation. This review describes procaine, which can produce epigenetic modification in four studies of cancer in vitro and in vivo and how, when combined with other anticancer drugs, increases the therapeutic index improving antitumor activity. The aim of this review is to present a general perspective of selected data that shows the progress of the investigation of cancer, defined as the study of reversible mechanisms interact on the DNA, altering gene expression without altering the structure genetics epigenetics. In the same way, to explain an usefulness of a drug, procaine, a local anesthetic in the demethylation of DNA and the consequent re-expression of tumor suppressor genes and its possible clinical application from the perspective of Neural Therapy, designed as a therapeutic alternative in that places a non-specific stimulation the patient's body to locate itself self-organize into a state of health. For this, an electronic search of Agora, E-Book, Ovid, Pubmed / Medline, was conducted using this information for analysis. (MED.UIS. 2011;24(2):XX-XX).
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Procaína, epigenética y terapia Neural en el cáncer, ¿una alternativa terapéutica?
2011Co-Authors: Juan Carlos Jiménez Illera, Maria Luisa CárdenasAbstract:Resumen Una marca distintiva del cancer humano desde la epigenetica es el silenciamiento de los genes supresores de tumores,junto con la hipermetilacion del ADN. En esta revision se describe como la procaina es capaz de producir modificacionepigenetica en cuatro estudios de cancer in vitro e in vivo, y como cuando se combina con otros farmacos antineoplasicosaumenta el indice terapeutico mejorando la actividad antitumoral. De esta manera, el objetivo es exponer una vision deconjunto de datos seleccionados que muestran los avances de la investigacion de la epigenetica del cancer, entendidacomo el estudio de los mecanismos reversibles que interactuan sobre el ADN, modificando la expresion de genes sin alterarla estructura genetica. Asi mismo, la utilidad de un medicamento, la procaina, un anestesico local en la desmetilaciondel ADN y la consecuente reexpresion de genes supresores de tumores, asi como su posible aplicacion en la clinica desdela optica de la terapia Neural, una terapeutica alternativa en la cual se coloca un estimulo inespecifico en el organismodel paciente para que el mismo busque autoorganizarse hacia un estado de salud. Para ello, se realizo una busquedaelectronica en Agora, E-Libro, Ovid, Pubmed/Medline. (MED.UIS. 2011;24(2):165-71).Palabras clave: Procaina. Cancer. Medicina alternativa. Metilacion de ADN. SUMARY Procaine, epigenetics and Neural Therapy, a therapeutic alternative?A hallmark of human cancer from epigenetics is the silencing of tumor suppressor genes,along with DNA hypermethylation.This review describes procaine, which can produce epigenetic modification in four studies of cancer in vitro and in vivoand how, when combined with other anticancer drugs, increases the therapeutic index improving antitumor activity. Theaim of this review is to present a general perspective of selected data that shows the progress of the investigation ofcancer, defined as the study of reversible mechanisms interact on the DNA, altering gene expression without altering thestructure genetics epigenetics. In the same way, to explain an usefulness of a drug, procaine, a local anesthetic in thedemethylation of DNA and the consequent re-expression of tumor suppressor genes and its possible clinical applicationfrom the perspective of Neural Therapy, designed as a therapeutic alternative in that places a non-specific stimulationthe patient's body to locate itself self-organize into a state of health. For this, an electronic search of Agora, E-Book,Ovid, Pubmed / Medline, was conducted using this information for analysis.(MED.UIS. 2011;24(2):165-71).Key words: Procaine. Cancer. Alternative medicine. DNA Methylation.
Uma Maheswari Krishnan - One of the best experts on this subject based on the ideXlab platform.
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development of biomaterial scaffold for nerve tissue engineering biomaterial mediated Neural regeneration
Journal of Biomedical Science, 2009Co-Authors: Anuradha Subramanian, Uma Maheswari Krishnan, Swaminathan SethuramanAbstract:Neural tissue repair and regeneration strategies have received a great deal of attention because it directly affects the quality of the patient's life. There are many scientific challenges to regenerate nerve while using conventional autologous nerve grafts and from the newly developed therapeutic strategies for the reconstruction of damaged nerves. Recent advancements in nerve regeneration have involved the application of tissue engineering principles and this has evolved a new perspective to Neural Therapy. The success of Neural tissue engineering is mainly based on the regulation of cell behavior and tissue progression through the development of a synthetic scaffold that is analogous to the natural extracellular matrix and can support three-dimensional cell cultures. As the natural extracellular matrix provides an ideal environment for topographical, electrical and chemical cues to the adhesion and proliferation of Neural cells, there exists a need to develop a synthetic scaffold that would be biocompatible, immunologically inert, conducting, biodegradable, and infection-resistant biomaterial to support neurite outgrowth. This review outlines the rationale for effective Neural tissue engineering through the use of suitable biomaterials and scaffolding techniques for fabrication of a construct that would allow the neurons to adhere, proliferate and eventually form nerves.
Patrick J. Lariccia - One of the best experts on this subject based on the ideXlab platform.
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Successful Treatment of Dyspareunia with an Integrative Medicine Approach: A Case Report.
Integrative medicine (Encinitas Calif.), 2019Co-Authors: Brenda Arthur, Myung Kyu Chung, Tracy Brobyn, Patrick J. LaricciaAbstract:A 50-year-old woman with a five-and-a-half-year history of dyspareunia was successfully treated with an integrative medicine approach, including Neural Therapy, osteopathic Therapy, acupuncture, and trigger point Therapy, resulting in complete resolution which has been maintained to the present day, nineteen years later. Further research is justified and recommended.
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Rapid resolution of concussion related symptoms in an 11-month-old male with integrative medicine assessment and treatment: Case report.
Clinical Case Reports, 2019Co-Authors: Myung Kyu Chung, Patrick J. LaricciaAbstract:Neural Therapy may have promise as a helpful, fast acting, and safe method of treating concussion symptoms.
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Resolving bulimia nervosa using an innovative Neural Therapy approach: two case reports.
Clinical Case Reports, 2017Co-Authors: Michael I. Gurevich, Myung Kyu Chung, Patrick J. LaricciaAbstract:Conventional treatment of Bulimia Nervosa is long term, expensive, and often ineffective. Neural Therapy holds promise for treating Bulimia Nervosa in a shorter term, lower cost, and more effective manner. Much of Neural Therapy involves the superficial injection of local anesthetic injections. Implementation into current practice would be feasible.
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Successful Integrative Medicine Assessment and Treatment of Chronic Pain Associated With Breast Surgery: A Report of 3 Cases.
Holistic Nursing Practice, 2017Co-Authors: Myung Kyu Chung, Patrick J. LaricciaAbstract:Presented is the first reported case series of chronic neck and back pain associated with breast scars from breast surgery and successfully treated with an integrative medicine assessment and treatment approach, which included the assessment technique of autonomic response testing and the scar Therapy technique of Neural Therapy. Implications for nursing practice are discussed.
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Successful treatment of chronic nausea and vomiting related to body piercing and tattooing with integrative medicine interventions.
Holistic Nursing Practice, 2015Co-Authors: M. Kyu Chung, Patrick J. LaricciaAbstract:Chronic nausea and vomiting of uncertain etiology can be debilitating and uncomfortable for patients while frustrating for clinicians. This article presents the case of a young woman with chronic nausea and vomiting of unknown etiology resulting from body piercing and tattoo scars on body areas that Chinese Medicine asserts are related to the gastrointestinal system. The patient had long-term total resolution after 1 treatment session consisting of Neural Therapy for scars resulting from a tongue ring, belly ring, and tattoo near her left wrist along with acupuncture treatment. The research community is called to further evaluate the possible association of body piercing and tattooing with nausea and vomiting along with the possible treatment options of Neural Therapy and acupuncture.
