The Experts below are selected from a list of 297 Experts worldwide ranked by ideXlab platform
M Garg - One of the best experts on this subject based on the ideXlab platform.
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radiation therapy Noncompliance and clinical outcomes in an urban academic cancer center
International Journal of Radiation Oncology Biology Physics, 2016Co-Authors: Nitin Ohri, Bruce D Rapkin, Chandan Guha, S Kalnicki, M GargAbstract:Purpose To examine associations between radiation therapy (RT) Noncompliance and clinical outcomes. Methods and Materials We reviewed all patients who completed courses of external beam RT with curative intent in our department from the years 2007 to 2012 for cancers of the head and neck, breast, lung, cervix, uterus, or rectum. Patients who missed 2 or more scheduled RT appointments (excluding planned treatment breaks) were deemed noncompliant. Univariate, multivariable, and propensity-matched analyses were performed to examine associations between RT Noncompliance and clinical outcomes. Results Of 1227 patients, 266 (21.7%) were noncompliant. With median follow-up of 50.9 months, 108 recurrences (8.8%) and 228 deaths (18.6%) occurred. In univariate analyses, RT Noncompliance was associated with increased recurrence risk (5-year cumulative incidence 16% vs 7%, P P P Conclusion For cancer patients being treated with curative intent, RT Noncompliance is associated with inferior clinical outcomes. The magnitudes of these effects demonstrate that RT Noncompliance can serve as a behavioral biomarker to identify high-risk patients who require additional interventions. Treatment compliance may mediate the associations that have been observed linking SES and clinical outcomes.
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predictors of radiation therapy Noncompliance in an urban academic cancer center
International Journal of Radiation Oncology Biology Physics, 2015Co-Authors: Nitin Ohri, Bruce D Rapkin, Debayan Guha, Hilda Hayneslewis, Chandan Guha, S Kalnicki, M GargAbstract:Purpose To quantify the frequency of patient Noncompliance in an urban radiation oncology department and identify predictors of Noncompliance. Methods and Materials We identified patients treated with external beam radiation therapy (RT) with curative intent in our department from 2007 to 2012 for 1 of 7 commonly treated malignancies. Patients who missed 2 or more scheduled RT appointments were deemed "noncompliant." An institutional database was referenced to obtain clinical and demographic information for each patient, as well as a quantitative estimate of each patient's socioeconomic status. Logistic regression was used to identify factors associated with RT Noncompliance. Results A total of 2184 patients met eligibility criteria. Of these, 442 (20.2%) were deemed "noncompliant." On multivariate analysis, statistically significant predictors of Noncompliance included diagnosis of head-and-neck, cervical, or uterine cancer, treatment during winter months, low socioeconomic status, and use of a long treatment course (all P Conclusion This is the first large effort examining patient Noncompliance with daily RT. We have identified demographic, clinical, and treatment-related factors that can be used to identify patients at high risk for Noncompliance. These findings may inform future strategies to improve adherence to prescribed therapy.
Nitin Ohri - One of the best experts on this subject based on the ideXlab platform.
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radiation therapy Noncompliance and clinical outcomes in an urban academic cancer center
International Journal of Radiation Oncology Biology Physics, 2016Co-Authors: Nitin Ohri, Bruce D Rapkin, Chandan Guha, S Kalnicki, M GargAbstract:Purpose To examine associations between radiation therapy (RT) Noncompliance and clinical outcomes. Methods and Materials We reviewed all patients who completed courses of external beam RT with curative intent in our department from the years 2007 to 2012 for cancers of the head and neck, breast, lung, cervix, uterus, or rectum. Patients who missed 2 or more scheduled RT appointments (excluding planned treatment breaks) were deemed noncompliant. Univariate, multivariable, and propensity-matched analyses were performed to examine associations between RT Noncompliance and clinical outcomes. Results Of 1227 patients, 266 (21.7%) were noncompliant. With median follow-up of 50.9 months, 108 recurrences (8.8%) and 228 deaths (18.6%) occurred. In univariate analyses, RT Noncompliance was associated with increased recurrence risk (5-year cumulative incidence 16% vs 7%, P P P Conclusion For cancer patients being treated with curative intent, RT Noncompliance is associated with inferior clinical outcomes. The magnitudes of these effects demonstrate that RT Noncompliance can serve as a behavioral biomarker to identify high-risk patients who require additional interventions. Treatment compliance may mediate the associations that have been observed linking SES and clinical outcomes.
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predictors of radiation therapy Noncompliance in an urban academic cancer center
International Journal of Radiation Oncology Biology Physics, 2015Co-Authors: Nitin Ohri, Bruce D Rapkin, Debayan Guha, Hilda Hayneslewis, Chandan Guha, S Kalnicki, M GargAbstract:Purpose To quantify the frequency of patient Noncompliance in an urban radiation oncology department and identify predictors of Noncompliance. Methods and Materials We identified patients treated with external beam radiation therapy (RT) with curative intent in our department from 2007 to 2012 for 1 of 7 commonly treated malignancies. Patients who missed 2 or more scheduled RT appointments were deemed "noncompliant." An institutional database was referenced to obtain clinical and demographic information for each patient, as well as a quantitative estimate of each patient's socioeconomic status. Logistic regression was used to identify factors associated with RT Noncompliance. Results A total of 2184 patients met eligibility criteria. Of these, 442 (20.2%) were deemed "noncompliant." On multivariate analysis, statistically significant predictors of Noncompliance included diagnosis of head-and-neck, cervical, or uterine cancer, treatment during winter months, low socioeconomic status, and use of a long treatment course (all P Conclusion This is the first large effort examining patient Noncompliance with daily RT. We have identified demographic, clinical, and treatment-related factors that can be used to identify patients at high risk for Noncompliance. These findings may inform future strategies to improve adherence to prescribed therapy.
Anat Gofen - One of the best experts on this subject based on the ideXlab platform.
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Reconciling policy dissonance: patterns of governmental response to policy Noncompliance
Policy Sciences, 2015Co-Authors: Anat GofenAbstract:Noncompliance is most often understood in the public policy literature as a problem of implementation and enforcement. Yet, this perhaps normative focus misses the role of Noncompliance as a source of policy change. To demonstrate this unexplored role, this study conceptualizes Noncompliance and subsequent governmental responses as an interactive, ongoing process, in which Noncompliance may gain social acceptance and governmental reaction changes over time. Manifestations of Noncompliance in health (immunization refusal, needle exchange programs), education (homeschooling), policing (community police), drug use (decriminalization of marijuana) and urban services (community gardening) suggest that governmental reaction is a dynamic, developing process, constituting a series of responses influenced by social acceptance of Noncompliance and by the latter’s implications. Each response may take on one of four patterns of legitimization: embracement (legitimization), adaptation (reluctant legitimization), acceptance (implicit legitimization) and stricter enforcement (delegitimization). A more nuanced portrayal of the interaction between Noncompliance and governmental reaction emphasizes a reciprocal relationship between policy makers and policy targets.
A F Salam - One of the best experts on this subject based on the ideXlab platform.
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AMCIS - Are Conceptualizations of Employee Compliance and Noncompliance in Information Security Research Adequate? Developing Taxonomies of Compliance and Noncompliance
2013Co-Authors: Jeffrey D Wall, Lakshmi S Iyer, A F SalamAbstract:This paper offers a grounded theory approach to a review of behavioral information security research. Behavioral information security research is in a nascent state, yet it is growing rapidly due to the importance of information security in organizations. This review examines a particular problem in security research, namely the lack of clear conceptualizations of employee compliance and Noncompliance with security policies and norms. This review finds that definitions of compliance and Noncompliance are taken-for-granted, which may indicate danger in examining results across studies. Based on existing research of compliance in the information systems field and other fields, this paper identifies four types of compliance and five types of Noncompliance along with dimensions of compliance and Noncompliance using a grounded theory approach.
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are conceptualizations of employee compliance and Noncompliance in information security research adequate developing taxonomies of compliance and Noncompliance
Americas Conference on Information Systems, 2013Co-Authors: Jeffrey D Wall, Lakshmi S Iyer, A F SalamAbstract:This paper offers a grounded theory approach to a review of behavioral information security research. Behavioral information security research is in a nascent state, yet it is growing rapidly due to the importance of information security in organizations. This review examines a particular problem in security research, namely the lack of clear conceptualizations of employee compliance and Noncompliance with security policies and norms. This review finds that definitions of compliance and Noncompliance are taken-for-granted, which may indicate danger in examining results across studies. Based on existing research of compliance in the information systems field and other fields, this paper identifies four types of compliance and five types of Noncompliance along with dimensions of compliance and Noncompliance using a grounded theory approach.
Bruce D Rapkin - One of the best experts on this subject based on the ideXlab platform.
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radiation therapy Noncompliance and clinical outcomes in an urban academic cancer center
International Journal of Radiation Oncology Biology Physics, 2016Co-Authors: Nitin Ohri, Bruce D Rapkin, Chandan Guha, S Kalnicki, M GargAbstract:Purpose To examine associations between radiation therapy (RT) Noncompliance and clinical outcomes. Methods and Materials We reviewed all patients who completed courses of external beam RT with curative intent in our department from the years 2007 to 2012 for cancers of the head and neck, breast, lung, cervix, uterus, or rectum. Patients who missed 2 or more scheduled RT appointments (excluding planned treatment breaks) were deemed noncompliant. Univariate, multivariable, and propensity-matched analyses were performed to examine associations between RT Noncompliance and clinical outcomes. Results Of 1227 patients, 266 (21.7%) were noncompliant. With median follow-up of 50.9 months, 108 recurrences (8.8%) and 228 deaths (18.6%) occurred. In univariate analyses, RT Noncompliance was associated with increased recurrence risk (5-year cumulative incidence 16% vs 7%, P P P Conclusion For cancer patients being treated with curative intent, RT Noncompliance is associated with inferior clinical outcomes. The magnitudes of these effects demonstrate that RT Noncompliance can serve as a behavioral biomarker to identify high-risk patients who require additional interventions. Treatment compliance may mediate the associations that have been observed linking SES and clinical outcomes.
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predictors of radiation therapy Noncompliance in an urban academic cancer center
International Journal of Radiation Oncology Biology Physics, 2015Co-Authors: Nitin Ohri, Bruce D Rapkin, Debayan Guha, Hilda Hayneslewis, Chandan Guha, S Kalnicki, M GargAbstract:Purpose To quantify the frequency of patient Noncompliance in an urban radiation oncology department and identify predictors of Noncompliance. Methods and Materials We identified patients treated with external beam radiation therapy (RT) with curative intent in our department from 2007 to 2012 for 1 of 7 commonly treated malignancies. Patients who missed 2 or more scheduled RT appointments were deemed "noncompliant." An institutional database was referenced to obtain clinical and demographic information for each patient, as well as a quantitative estimate of each patient's socioeconomic status. Logistic regression was used to identify factors associated with RT Noncompliance. Results A total of 2184 patients met eligibility criteria. Of these, 442 (20.2%) were deemed "noncompliant." On multivariate analysis, statistically significant predictors of Noncompliance included diagnosis of head-and-neck, cervical, or uterine cancer, treatment during winter months, low socioeconomic status, and use of a long treatment course (all P Conclusion This is the first large effort examining patient Noncompliance with daily RT. We have identified demographic, clinical, and treatment-related factors that can be used to identify patients at high risk for Noncompliance. These findings may inform future strategies to improve adherence to prescribed therapy.
