The Experts below are selected from a list of 126 Experts worldwide ranked by ideXlab platform
Phillip Hay - One of the best experts on this subject based on the ideXlab platform.
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interleukin 8 levels in seminal plasma in chronic prostatitis chronic pelvic pain syndrome and Nonspecific Urethritis
BJUI, 2006Co-Authors: Abbas Khadra, Patricia S. Fletcher, Graz Luzzi, Robin J. Shattock, Phillip HayAbstract:OBJECTIVE To investigate whether a range of cytokines were detectable in the seminal plasma and urine of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and Nonspecific Urethritis (NSU), and whether cytokine levels correlated with symptom severity in CP/CPPS. PATIENTS AND METHODS In all, 87 men participated, 33 with CP/CPPS, 31 with NSU, and 23 controls. Interleukin (IL)-1β, IL-2, IL-6, IL-8 and IL-10 were measured in seminal plasma and first pass urine, and the results were correlated with scores for pain, urinary symptoms and quality-of-life impact using a validated symptom index, the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). RESULTS Seminal plasma levels of IL-8 were higher in men with CP/CPPS and NSU than in controls (P < 0.001), and the levels correlated with NIH-CPSI symptom scores in men with CP/CPPS. There were no significant differences in urinary IL-8 levels in the three groups, and no significant differences in levels of the other cytokines in either semen or urine. CONCLUSION Semen IL-8 levels correlate with subjective symptoms in men with CP/CPPS. IL-8 might contribute to the pathophysiology of CP/CPPS and NSU, and elevated levels might be a useful marker of the condition.
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Interleukin-8 levels in seminal plasma in chronic prostatitis/chronic pelvic pain syndrome and Nonspecific Urethritis.
BJU international, 2006Co-Authors: Abbas Khadra, Patricia S. Fletcher, Graz Luzzi, Robin J. Shattock, Phillip HayAbstract:OBJECTIVE To investigate whether a range of cytokines were detectable in the seminal plasma and urine of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and Nonspecific Urethritis (NSU), and whether cytokine levels correlated with symptom severity in CP/CPPS. PATIENTS AND METHODS In all, 87 men participated, 33 with CP/CPPS, 31 with NSU, and 23 controls. Interleukin (IL)-1β, IL-2, IL-6, IL-8 and IL-10 were measured in seminal plasma and first pass urine, and the results were correlated with scores for pain, urinary symptoms and quality-of-life impact using a validated symptom index, the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). RESULTS Seminal plasma levels of IL-8 were higher in men with CP/CPPS and NSU than in controls (P
Chinyelu C. Ekweozor - One of the best experts on this subject based on the ideXlab platform.
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Isolation of herpes simplex virus from sexually transmitted disease patients in Ibadan, Nigeria.
Sexually transmitted diseases, 1994Co-Authors: Festus D. Adu, Chinyelu C. EkweozorAbstract:In Nigeria the sexually transmitted disease clinic staff at the hospital of the University of Ibadan collected 153 urethral vaginal and endocervical samples from 116 patients between November 1991 and November 1992 so researchers could isolate identify and type the herpes simplex virus (HSV). They used the complete fixation test and the indirect immunofluorescent antibody technique to confirm HSV. The patients also had genital herpes (31.6%) Neisseria gonorrhoeae Urethritis (15.8%) Nonspecific Urethritis (15.8%) candidiasis (21%) genital warts (10.5%) and trichomoniasis (1%). No one had syphilis. The laboratory staff isolated HSV from only 7 samples (4.6% of all samples). All 7 isolates were from males (genital ulcer and urethral samples). Five of the isolates were HSV-2 and 2 were HSV-1. This study was the first documented isolation of HSV in Nigeria. These findings provide baseline data on genital herpes for projected studies. Further research should examine the significance of these findings for other areas particularly HIV transmission and immunocompromised patients.
Abbas Khadra - One of the best experts on this subject based on the ideXlab platform.
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interleukin 8 levels in seminal plasma in chronic prostatitis chronic pelvic pain syndrome and Nonspecific Urethritis
BJUI, 2006Co-Authors: Abbas Khadra, Patricia S. Fletcher, Graz Luzzi, Robin J. Shattock, Phillip HayAbstract:OBJECTIVE To investigate whether a range of cytokines were detectable in the seminal plasma and urine of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and Nonspecific Urethritis (NSU), and whether cytokine levels correlated with symptom severity in CP/CPPS. PATIENTS AND METHODS In all, 87 men participated, 33 with CP/CPPS, 31 with NSU, and 23 controls. Interleukin (IL)-1β, IL-2, IL-6, IL-8 and IL-10 were measured in seminal plasma and first pass urine, and the results were correlated with scores for pain, urinary symptoms and quality-of-life impact using a validated symptom index, the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). RESULTS Seminal plasma levels of IL-8 were higher in men with CP/CPPS and NSU than in controls (P < 0.001), and the levels correlated with NIH-CPSI symptom scores in men with CP/CPPS. There were no significant differences in urinary IL-8 levels in the three groups, and no significant differences in levels of the other cytokines in either semen or urine. CONCLUSION Semen IL-8 levels correlate with subjective symptoms in men with CP/CPPS. IL-8 might contribute to the pathophysiology of CP/CPPS and NSU, and elevated levels might be a useful marker of the condition.
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Interleukin-8 levels in seminal plasma in chronic prostatitis/chronic pelvic pain syndrome and Nonspecific Urethritis.
BJU international, 2006Co-Authors: Abbas Khadra, Patricia S. Fletcher, Graz Luzzi, Robin J. Shattock, Phillip HayAbstract:OBJECTIVE To investigate whether a range of cytokines were detectable in the seminal plasma and urine of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and Nonspecific Urethritis (NSU), and whether cytokine levels correlated with symptom severity in CP/CPPS. PATIENTS AND METHODS In all, 87 men participated, 33 with CP/CPPS, 31 with NSU, and 23 controls. Interleukin (IL)-1β, IL-2, IL-6, IL-8 and IL-10 were measured in seminal plasma and first pass urine, and the results were correlated with scores for pain, urinary symptoms and quality-of-life impact using a validated symptom index, the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). RESULTS Seminal plasma levels of IL-8 were higher in men with CP/CPPS and NSU than in controls (P
Festus D. Adu - One of the best experts on this subject based on the ideXlab platform.
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Isolation of herpes simplex virus from sexually transmitted disease patients in Ibadan, Nigeria.
Sexually transmitted diseases, 1994Co-Authors: Festus D. Adu, Chinyelu C. EkweozorAbstract:In Nigeria the sexually transmitted disease clinic staff at the hospital of the University of Ibadan collected 153 urethral vaginal and endocervical samples from 116 patients between November 1991 and November 1992 so researchers could isolate identify and type the herpes simplex virus (HSV). They used the complete fixation test and the indirect immunofluorescent antibody technique to confirm HSV. The patients also had genital herpes (31.6%) Neisseria gonorrhoeae Urethritis (15.8%) Nonspecific Urethritis (15.8%) candidiasis (21%) genital warts (10.5%) and trichomoniasis (1%). No one had syphilis. The laboratory staff isolated HSV from only 7 samples (4.6% of all samples). All 7 isolates were from males (genital ulcer and urethral samples). Five of the isolates were HSV-2 and 2 were HSV-1. This study was the first documented isolation of HSV in Nigeria. These findings provide baseline data on genital herpes for projected studies. Further research should examine the significance of these findings for other areas particularly HIV transmission and immunocompromised patients.
Robin J. Shattock - One of the best experts on this subject based on the ideXlab platform.
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interleukin 8 levels in seminal plasma in chronic prostatitis chronic pelvic pain syndrome and Nonspecific Urethritis
BJUI, 2006Co-Authors: Abbas Khadra, Patricia S. Fletcher, Graz Luzzi, Robin J. Shattock, Phillip HayAbstract:OBJECTIVE To investigate whether a range of cytokines were detectable in the seminal plasma and urine of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and Nonspecific Urethritis (NSU), and whether cytokine levels correlated with symptom severity in CP/CPPS. PATIENTS AND METHODS In all, 87 men participated, 33 with CP/CPPS, 31 with NSU, and 23 controls. Interleukin (IL)-1β, IL-2, IL-6, IL-8 and IL-10 were measured in seminal plasma and first pass urine, and the results were correlated with scores for pain, urinary symptoms and quality-of-life impact using a validated symptom index, the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). RESULTS Seminal plasma levels of IL-8 were higher in men with CP/CPPS and NSU than in controls (P < 0.001), and the levels correlated with NIH-CPSI symptom scores in men with CP/CPPS. There were no significant differences in urinary IL-8 levels in the three groups, and no significant differences in levels of the other cytokines in either semen or urine. CONCLUSION Semen IL-8 levels correlate with subjective symptoms in men with CP/CPPS. IL-8 might contribute to the pathophysiology of CP/CPPS and NSU, and elevated levels might be a useful marker of the condition.
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Interleukin-8 levels in seminal plasma in chronic prostatitis/chronic pelvic pain syndrome and Nonspecific Urethritis.
BJU international, 2006Co-Authors: Abbas Khadra, Patricia S. Fletcher, Graz Luzzi, Robin J. Shattock, Phillip HayAbstract:OBJECTIVE To investigate whether a range of cytokines were detectable in the seminal plasma and urine of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and Nonspecific Urethritis (NSU), and whether cytokine levels correlated with symptom severity in CP/CPPS. PATIENTS AND METHODS In all, 87 men participated, 33 with CP/CPPS, 31 with NSU, and 23 controls. Interleukin (IL)-1β, IL-2, IL-6, IL-8 and IL-10 were measured in seminal plasma and first pass urine, and the results were correlated with scores for pain, urinary symptoms and quality-of-life impact using a validated symptom index, the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). RESULTS Seminal plasma levels of IL-8 were higher in men with CP/CPPS and NSU than in controls (P
