The Experts below are selected from a list of 3084 Experts worldwide ranked by ideXlab platform
Hyunsik Nam - One of the best experts on this subject based on the ideXlab platform.
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synthesis and pharmacological evaluation of 3 aryl 3 azolylpropan 1 amines as selective triple serotonin norepinephrine dopamine Reuptake Inhibitors
Bioorganic & Medicinal Chemistry Letters, 2010Co-Authors: Kiho Lee, Chuneung Park, Kyunghyun Min, Yongje Shin, Coomin Chung, H S Kim, Haejeoung Yoon, Eunju Ryu, Yujin Shin, Hyunsik NamAbstract:A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine Reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In vivo models were used to evaluate the compound 19r for antidepressive, anxiolytic, and analgesic activity.
Kiho Lee - One of the best experts on this subject based on the ideXlab platform.
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synthesis and pharmacological evaluation of 3 aryl 3 azolylpropan 1 amines as selective triple serotonin norepinephrine dopamine Reuptake Inhibitors
ChemInform, 2011Co-Authors: Kiho LeeAbstract:Compound (IIa) possesses antidepressive, anxiolytic and analgesic activities in animal models.
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synthesis and pharmacological evaluation of 3 aryl 3 azolylpropan 1 amines as selective triple serotonin norepinephrine dopamine Reuptake Inhibitors
Bioorganic & Medicinal Chemistry Letters, 2010Co-Authors: Kiho Lee, Chuneung Park, Kyunghyun Min, Yongje Shin, Coomin Chung, H S Kim, Haejeoung Yoon, Eunju Ryu, Yujin Shin, Hyunsik NamAbstract:A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine Reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In vivo models were used to evaluate the compound 19r for antidepressive, anxiolytic, and analgesic activity.
Kyunghyun Min - One of the best experts on this subject based on the ideXlab platform.
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synthesis and pharmacological evaluation of 3 aryl 3 azolylpropan 1 amines as selective triple serotonin norepinephrine dopamine Reuptake Inhibitors
Bioorganic & Medicinal Chemistry Letters, 2010Co-Authors: Kiho Lee, Chuneung Park, Kyunghyun Min, Yongje Shin, Coomin Chung, H S Kim, Haejeoung Yoon, Eunju Ryu, Yujin Shin, Hyunsik NamAbstract:A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine Reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In vivo models were used to evaluate the compound 19r for antidepressive, anxiolytic, and analgesic activity.
Yujin Shin - One of the best experts on this subject based on the ideXlab platform.
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synthesis and pharmacological evaluation of 3 aryl 3 azolylpropan 1 amines as selective triple serotonin norepinephrine dopamine Reuptake Inhibitors
Bioorganic & Medicinal Chemistry Letters, 2010Co-Authors: Kiho Lee, Chuneung Park, Kyunghyun Min, Yongje Shin, Coomin Chung, H S Kim, Haejeoung Yoon, Eunju Ryu, Yujin Shin, Hyunsik NamAbstract:A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine Reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In vivo models were used to evaluate the compound 19r for antidepressive, anxiolytic, and analgesic activity.
Eunju Ryu - One of the best experts on this subject based on the ideXlab platform.
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synthesis and pharmacological evaluation of 3 aryl 3 azolylpropan 1 amines as selective triple serotonin norepinephrine dopamine Reuptake Inhibitors
Bioorganic & Medicinal Chemistry Letters, 2010Co-Authors: Kiho Lee, Chuneung Park, Kyunghyun Min, Yongje Shin, Coomin Chung, H S Kim, Haejeoung Yoon, Eunju Ryu, Yujin Shin, Hyunsik NamAbstract:A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine Reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In vivo models were used to evaluate the compound 19r for antidepressive, anxiolytic, and analgesic activity.
