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Harry Vennema - One of the best experts on this subject based on the ideXlab platform.

  • chronic Norovirus Infection among solid organ recipients in a tertiary care hospital the netherlands 2006 2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006–2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006-2014.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2016
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32-1164 days). This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population. Copyright © 2016. Published by Elsevier Ltd.

J Van Beek - One of the best experts on this subject based on the ideXlab platform.

  • chronic Norovirus Infection among solid organ recipients in a tertiary care hospital the netherlands 2006 2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006–2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006-2014.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2016
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32-1164 days). This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population. Copyright © 2016. Published by Elsevier Ltd.

Godfrey Chifung Chan - One of the best experts on this subject based on the ideXlab platform.

  • Norovirus Infection in pediatric hematopoietic stem cell transplantation recipients incidence risk factors and outcome
    Biology of Blood and Marrow Transplantation, 2012
    Co-Authors: Joseph D F Robles, Daniel K L Cheuk, Shau Yin Ha, Alan K S Chiang, Godfrey Chifung Chan
    Abstract:

    Norovirus Infections are increasingly being recognized as important causes of diarrhea in hematopoietic stem cell transplantation (HSCT) recipients. This retrospective study aimed to evaluate the cumulative incidence, risk factors, and outcomes of Norovirus Infection in pediatric HSCT recipients. Among 55 patients age P  = .043) and administration of fludarabine ( P  = .002) and alemtuzumab ( P  = .011). The median time to viral clearance was 145 days (range, 13-263 days). Four-year survival was similar in Norovirus-infected patients and noninfected patients (56.3% versus 58.3%).

Kadir Caliskan - One of the best experts on this subject based on the ideXlab platform.

  • chronic Norovirus Infection among solid organ recipients in a tertiary care hospital the netherlands 2006 2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006–2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006-2014.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2016
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32-1164 days). This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population. Copyright © 2016. Published by Elsevier Ltd.

Karlien Cransberg - One of the best experts on this subject based on the ideXlab platform.

  • chronic Norovirus Infection among solid organ recipients in a tertiary care hospital the netherlands 2006 2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006–2014
    Clinical Microbiology and Infection, 2017
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Abstract Objectives Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. Methods The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. Results In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32–1164 days). Conclusions This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population.

  • Chronic Norovirus Infection among solid organ recipients in a tertiary care hospital, the Netherlands, 2006-2014.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2016
    Co-Authors: J Van Beek, A A Van Der Eijk, Pieter L A Fraaij, Kadir Caliskan, Karlien Cransberg, Michiel Dalinghaus, Rogier A S Hoek, H J Metselaar, J Roodnat, Harry Vennema
    Abstract:

    Immunocompromised patients can suffer prolonged Norovirus symptoms and virus shedding for many years. Little is known about the prevalence of chronic Norovirus Infection among solid organ transplant (SOT) recipients. In this study, 2182 SOT recipients were retrospectively tested for chronic Norovirus Infection. The first and last Norovirus positive faecal samples of SOT recipients were sequenced to distinguish between persisting Infection and re-Infection. Patient charts were reviewed to obtain data on health status and treatments. In all, 101 of 2182 (4.6%) recipients were Norovirus infected and 23 (22.8%) of these developed chronic Norovirus Infection. Chronic Norovirus Infection was found among allogeneic heart, kidney and lung transplant recipients. The median shedding period at the end of the study period was 218 days (range 32-1164 days). This study shows that chronic Norovirus Infection is not a rare phenomenon among SOT recipients in a tertiary-care hospital. Further research is needed to study the risk of Norovirus transmission to other immunocompromised patients in the hospital and to the general population. Copyright © 2016. Published by Elsevier Ltd.