The Experts below are selected from a list of 96 Experts worldwide ranked by ideXlab platform
César Grande - One of the best experts on this subject based on the ideXlab platform.
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determination of the optimized individual kinetic constants of the aminolysis reaction in basic medium of 3 lactam antibiotics by a Numerical Computational Method
Journal of Pharmaceutical Sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
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Determination of the Optimized Individual Kinetic Constants of the Aminolysis Reaction in Basic Medium of /3-Lactam Antibiotics by a Numerical Computational Method
Journal of pharmaceutical sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
Abel Lujan - One of the best experts on this subject based on the ideXlab platform.
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determination of the optimized individual kinetic constants of the aminolysis reaction in basic medium of 3 lactam antibiotics by a Numerical Computational Method
Journal of Pharmaceutical Sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
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Determination of the Optimized Individual Kinetic Constants of the Aminolysis Reaction in Basic Medium of /3-Lactam Antibiotics by a Numerical Computational Method
Journal of pharmaceutical sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
M. Del Mar Canedo - One of the best experts on this subject based on the ideXlab platform.
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determination of the optimized individual kinetic constants of the aminolysis reaction in basic medium of 3 lactam antibiotics by a Numerical Computational Method
Journal of Pharmaceutical Sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
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Determination of the Optimized Individual Kinetic Constants of the Aminolysis Reaction in Basic Medium of /3-Lactam Antibiotics by a Numerical Computational Method
Journal of pharmaceutical sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
José Luis González - One of the best experts on this subject based on the ideXlab platform.
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determination of the optimized individual kinetic constants of the aminolysis reaction in basic medium of 3 lactam antibiotics by a Numerical Computational Method
Journal of Pharmaceutical Sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
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Determination of the Optimized Individual Kinetic Constants of the Aminolysis Reaction in Basic Medium of /3-Lactam Antibiotics by a Numerical Computational Method
Journal of pharmaceutical sciences, 1993Co-Authors: Abel Lujan, José Luis González, M. Del Mar Canedo, César GrandeAbstract:The individual kinetic constants of the aminolysis reaction in basic medium of several beta-lactam compounds (6-aminopenicillanic acid, carbenicillin, 7-aminocephalosporanic acid, and cephalothin) are determined and improved by application of a Computational Method KINBETA. The Method uses a modified version of the AGDC optimization algorithm adapted to the reaction system. Initial estimates of the constants for this reaction, obtained from the conventional Methodology reported in the literature, were used. The Computational Method applied is self-consistent and affords both a considerable saving in experimental time and more reliable and exact results.
Khalil Maalej - One of the best experts on this subject based on the ideXlab platform.
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quasi static fracture global minimizer of the regularized energy
Applied Mechanics and Materials, 2012Co-Authors: Hamdi Hentati, Radhi Abdelmoula, Aref Maalej, Khalil MaalejAbstract:Fracture mechanics has been revisited aimed at modeling brittle fracture based on Griffith viewpoint. The purpose of this work is to present a Numerical Computational Method for solving the quasi static crack propagation based on the variational theory. It requires no prior knowledge of the crack path or of its topology. Moreover, it is capable of modeling crack initiation. At the Numerical level, we use a standard linear (P1) Lagrange finite element Method for space discretization. We perform Numerical simulations of a piece of brittle material without initial crack. We show also the necessity of adding the backtracking algorithm to alternate minimizations algorithm to ensure the convergence of the alternate minimizations algorithm to a global minimizer.
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Quasi Static Fracture – Global Minimizer of the Regularized Energy
Applied Mechanics and Materials, 2012Co-Authors: Hamdi Hentati, Radhi Abdelmoula, Aref Maalej, Khalil MaalejAbstract:Fracture mechanics has been revisited aimed at modeling brittle fracture based on Griffith viewpoint. The purpose of this work is to present a Numerical Computational Method for solving the quasi static crack propagation based on the variational theory. It requires no prior knowledge of the crack path or of its topology. Moreover, it is capable of modeling crack initiation. At the Numerical level, we use a standard linear (P1) Lagrange finite element Method for space discretization. We perform Numerical simulations of a piece of brittle material without initial crack. We show also the necessity of adding the backtracking algorithm to alternate minimizations algorithm to ensure the convergence of the alternate minimizations algorithm to a global minimizer.
