The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Walter C Willett - One of the best experts on this subject based on the ideXlab platform.
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dairy food and Nutrient Intake in different life periods in relation to risk of ovarian cancer
Cancer Causes & Control, 2014Co-Authors: Melissa A Merritt, Walter C Willett, Susan E Hankinson, Elizabeth M Poole, Shelley S TworogerAbstract:High lactose Intake has been suggested to increase epithelial ovarian cancer (EOC) risk. We evaluated the association between lactose consumed during specific life periods (high school, premenopause, and postmenopause) and later risk of EOC. We assessed the association of dairy food and Nutrient Intake with risk of EOC during 28 years of follow-up including 764 cases in the Nurses’ Health Study (NHS) and NHSII. Cox proportional hazards regression was used to model the hazard ratios (HRs) and 95 % confidence intervals (CIs) for EOC across categories of dairy food or Nutrient Intake. We examined dietary Intake in adulthood overall, as well as during premenopausal/postmenopausal years and high school. In analyses of the highest versus lowest cumulative average Intake in adulthood, we observed a non-significant inverse association with skim milk Intake (HR 0.76, 95 % CI 0.54–1.06, p trend = 0.05), a non-significant inverse association with lactose Intake (HR 0.87, 95 % CI 0.69–1.11, p trend = 0.22) and no association with consumption of whole milk, dairy calcium, or dairy fat. Similar risk estimates were observed for dairy food/Nutrient Intake during high school, premenopause or postmenopause. Lactose Intake in adulthood was inversely associated with risk of endometrioid EOC (HR 0.32, 95 % CI 0.16–0.65, p trend < 0.001). These findings do not support the hypothesis that higher lactose Intake increases EOC risk. The inverse association with endometrioid tumors deserves further study.
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long term Nutrient Intake and 5 year change in nuclear lens opacities
Archives of Ophthalmology, 2005Co-Authors: Paul F Jacques, Walter C Willett, Susan E Hankinson, Gail Rogers, William H Tung, Allen Taylor, Suzen M Moeller, Jose Ludovico, Leo T ChylackAbstract:Objective To determine if usual Nutrient Intake is related to a 5-year change in the amount of lens nuclear opacification assessed by computer-assisted image analysis. Design A sample of 408 Boston, Mass–area women from the Nurses’ Health Study aged 52 to 74 years at baseline participated in a 5-year study related to nutrition and vision. Usual Nutrient Intake was calculated as the average Intake from 5 food frequency questionnaires that were collected over a 13- to 15-year period before the baseline evaluation of lens nuclear density. Duration of vitamin supplement use before baseline was determined from 7 questionnaires collected during this same period. We assessed the degree of nuclear density (opacification) using computer-assisted image analysis of digital lens images with amount of nuclear density measured as a function of average pixel gray scale, ranging from 0 (clear) to 255 (black). Results Median (range) baseline and follow-up nuclear densities were 44 (19 to 102) and 63 (32 to 213). The median (range) 5-year change in nuclear density was 18 (−29 to 134) and was positively correlated with the amount of opacification at baseline (Spearman correlation coefficient = 0.35; P P trend = .03) and thiamin ( P trend = .04) and duration of vitamin E supplement use ( P trend = .006). Conclusion Our results suggest that long-term use of vitamin E supplements and higher riboflavin and/or thiamin Intake may reduce the progression of age-related lens opacification.
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long term Nutrient Intake and early age related nuclear lens opacities
Archives of Ophthalmology, 2001Co-Authors: Paul F Jacques, Leo T Chylack, Susan E Hankinson, Patricia M Khu, Gail Rogers, Judith Friend, William H Tung, John K Wolfe, Nita Padhye, Walter C WillettAbstract:Objective To assess the relation between usual Nutrient Intake and subsequently diagnosed age-related nuclear lens opacities. Subjects Four hundred seventy-eight nondiabetic women aged 53 to 73 years from the Boston, Mass, area without previously diagnosed cataracts sampled from the Nurses' Health Study cohort. Methods Usual Nutrient Intake was calculated as the average Intake from 5 food frequency questionnaires that were collected during a 13- to 15-year period before the evaluation of lens opacities. The duration of vitamin supplement use was determined from 7 questionnaires collected during this same period. We defined nuclear opacities as a nuclear opalescence grade of 2.5 or higher using the Lens Opacification Classification System III. Results The prevalence of nuclear opacification was significantly lower in the highest Nutrient Intake quintile category relative to the lowest quintile category for vitamin C ( P P = .02), riboflavin ( P = .005), folate ( P = .009), β-carotene ( P = .04), and lutein/zeaxanthin ( P = .03). After adjustment for other Nutrients, only vitamin C Intake remained significantly associated ( P = .003 for trend) with the prevalence of nuclear opacities. The prevalence of nuclear opacities was significantly lower ( P P = .004 for trend), vitamin E ( P = .03 for trend), and multivitamin ( P = .04 for trend) supplements, but only duration of vitamin C supplement use remained significantly associated with nuclear opacities after mutual adjustment for use of vitamin E ( P = .05 for trend) or multivitamin ( P = .02 for trend) supplements. The prevalence of nuclear opacities was significantly lower ( P = .004) for women who used a vitamin C supplement for 10 or more years relative to women who never used vitamin C supplements (odds ratio, 0.36; 95% confidence interval, 0.18-0.72). Plasma measures of vitamins C and E taken at the eye examination were also inversely associated with the prevalence of nuclear opacities. Conclusion These results provide additional evidence that antioxidant Nutrients play a role in the prevention of age-related nuclear lens opacities.
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the impact of edentulousness on food and Nutrient Intake
Journal of the American Dental Association, 1996Co-Authors: Kaumudi Joshipura, Walter C Willett, Chester W DouglassAbstract:The authors collected dietary Intake data about the food and Nutrient Intake of 49,501 male health professionals. Edentulous participants consumed fewer vegetables, less fiber and carotene, and more cholesterol, saturated fat and calories than participants with 25 or more teeth. These factors could increase the risks of cancer and cardiovascular disease. Mean differences in Intake ranged from 2 to 13 percent, independent of age, smoking, exercise and profession. Longitudinal analyses suggest that tooth loss may lead to detrimental changes in diet.
Susan E Hankinson - One of the best experts on this subject based on the ideXlab platform.
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dairy food and Nutrient Intake in different life periods in relation to risk of ovarian cancer
Cancer Causes & Control, 2014Co-Authors: Melissa A Merritt, Walter C Willett, Susan E Hankinson, Elizabeth M Poole, Shelley S TworogerAbstract:High lactose Intake has been suggested to increase epithelial ovarian cancer (EOC) risk. We evaluated the association between lactose consumed during specific life periods (high school, premenopause, and postmenopause) and later risk of EOC. We assessed the association of dairy food and Nutrient Intake with risk of EOC during 28 years of follow-up including 764 cases in the Nurses’ Health Study (NHS) and NHSII. Cox proportional hazards regression was used to model the hazard ratios (HRs) and 95 % confidence intervals (CIs) for EOC across categories of dairy food or Nutrient Intake. We examined dietary Intake in adulthood overall, as well as during premenopausal/postmenopausal years and high school. In analyses of the highest versus lowest cumulative average Intake in adulthood, we observed a non-significant inverse association with skim milk Intake (HR 0.76, 95 % CI 0.54–1.06, p trend = 0.05), a non-significant inverse association with lactose Intake (HR 0.87, 95 % CI 0.69–1.11, p trend = 0.22) and no association with consumption of whole milk, dairy calcium, or dairy fat. Similar risk estimates were observed for dairy food/Nutrient Intake during high school, premenopause or postmenopause. Lactose Intake in adulthood was inversely associated with risk of endometrioid EOC (HR 0.32, 95 % CI 0.16–0.65, p trend < 0.001). These findings do not support the hypothesis that higher lactose Intake increases EOC risk. The inverse association with endometrioid tumors deserves further study.
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long term Nutrient Intake and 5 year change in nuclear lens opacities
Archives of Ophthalmology, 2005Co-Authors: Paul F Jacques, Walter C Willett, Susan E Hankinson, Gail Rogers, William H Tung, Allen Taylor, Suzen M Moeller, Jose Ludovico, Leo T ChylackAbstract:Objective To determine if usual Nutrient Intake is related to a 5-year change in the amount of lens nuclear opacification assessed by computer-assisted image analysis. Design A sample of 408 Boston, Mass–area women from the Nurses’ Health Study aged 52 to 74 years at baseline participated in a 5-year study related to nutrition and vision. Usual Nutrient Intake was calculated as the average Intake from 5 food frequency questionnaires that were collected over a 13- to 15-year period before the baseline evaluation of lens nuclear density. Duration of vitamin supplement use before baseline was determined from 7 questionnaires collected during this same period. We assessed the degree of nuclear density (opacification) using computer-assisted image analysis of digital lens images with amount of nuclear density measured as a function of average pixel gray scale, ranging from 0 (clear) to 255 (black). Results Median (range) baseline and follow-up nuclear densities were 44 (19 to 102) and 63 (32 to 213). The median (range) 5-year change in nuclear density was 18 (−29 to 134) and was positively correlated with the amount of opacification at baseline (Spearman correlation coefficient = 0.35; P P trend = .03) and thiamin ( P trend = .04) and duration of vitamin E supplement use ( P trend = .006). Conclusion Our results suggest that long-term use of vitamin E supplements and higher riboflavin and/or thiamin Intake may reduce the progression of age-related lens opacification.
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long term Nutrient Intake and early age related nuclear lens opacities
Archives of Ophthalmology, 2001Co-Authors: Paul F Jacques, Leo T Chylack, Susan E Hankinson, Patricia M Khu, Gail Rogers, Judith Friend, William H Tung, John K Wolfe, Nita Padhye, Walter C WillettAbstract:Objective To assess the relation between usual Nutrient Intake and subsequently diagnosed age-related nuclear lens opacities. Subjects Four hundred seventy-eight nondiabetic women aged 53 to 73 years from the Boston, Mass, area without previously diagnosed cataracts sampled from the Nurses' Health Study cohort. Methods Usual Nutrient Intake was calculated as the average Intake from 5 food frequency questionnaires that were collected during a 13- to 15-year period before the evaluation of lens opacities. The duration of vitamin supplement use was determined from 7 questionnaires collected during this same period. We defined nuclear opacities as a nuclear opalescence grade of 2.5 or higher using the Lens Opacification Classification System III. Results The prevalence of nuclear opacification was significantly lower in the highest Nutrient Intake quintile category relative to the lowest quintile category for vitamin C ( P P = .02), riboflavin ( P = .005), folate ( P = .009), β-carotene ( P = .04), and lutein/zeaxanthin ( P = .03). After adjustment for other Nutrients, only vitamin C Intake remained significantly associated ( P = .003 for trend) with the prevalence of nuclear opacities. The prevalence of nuclear opacities was significantly lower ( P P = .004 for trend), vitamin E ( P = .03 for trend), and multivitamin ( P = .04 for trend) supplements, but only duration of vitamin C supplement use remained significantly associated with nuclear opacities after mutual adjustment for use of vitamin E ( P = .05 for trend) or multivitamin ( P = .02 for trend) supplements. The prevalence of nuclear opacities was significantly lower ( P = .004) for women who used a vitamin C supplement for 10 or more years relative to women who never used vitamin C supplements (odds ratio, 0.36; 95% confidence interval, 0.18-0.72). Plasma measures of vitamins C and E taken at the eye examination were also inversely associated with the prevalence of nuclear opacities. Conclusion These results provide additional evidence that antioxidant Nutrients play a role in the prevention of age-related nuclear lens opacities.
Praveen S Goday - One of the best experts on this subject based on the ideXlab platform.
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systematic review of Nutrient Intake and growth in children with multiple ige mediated food allergies
Nutrition in Clinical Practice, 2013Co-Authors: Cassandra Sova, Mary Beth Feuling, Megan Baumler, Linda Gleason, Jonathan S Tam, Heidi Zafra, Praveen S GodayAbstract:Background: Food allergies affect up to 8% of American children. The current recommended treatment for food allergies is strict elimination of the allergens from the diet. Dietary elimination of Nutrient-dense foods may result in inadequate Nutrient Intake and impaired growth. The purpose of this review was to critically analyze available research on the effect of an elimination diet on Nutrient Intake and growth in children with multiple food allergies. Methods: A systematic review of the literature was conducted and a workgroup was established to critically analyze each relevant article. The findings were summarized and a conclusion was generated. Results: Six studies were analyzed. One study found that children with food allergies are more likely to be malnourished than children without food allergies. Three studies found that children with multiple food allergies were shorter than children with 1 food allergy. Four studies assessed Nutrient Intake of children with multiple food allergies, but the incl...
Satoshi Sasaki - One of the best experts on this subject based on the ideXlab platform.
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school lunches in japan their contribution to healthier Nutrient Intake among elementary school and junior high school children
Public Health Nutrition, 2017Co-Authors: Keiko Asakura, Satoshi SasakiAbstract:Objective The role of school lunches in diet quality has not been well studied. Here, we aimed to determine the contribution of school lunches to overall Nutrient Intake in Japanese schoolchildren. Design The study was conducted nationwide under a cross-sectional design. A non-consecutive, three-day diet record was performed on two school days and a non-school day separately. The prevalence of inadequate Nutrient Intake was estimated for Intakes on one of the school days and the non-school day, and for daily habitual Intake estimated by the best-power method. The relationship between food Intake and Nutrient Intake adequacy was examined. Setting Fourteen elementary and thirteen junior high schools in Japan. Subjects Elementary-school children (n 629) and junior high-school children (n 281). Results Intakes between the school and non-school days were significantly different for ≥60 % of Nutrients. Almost all inadequacies were more prevalent on the non-school day. Regarding habitual Intake, a high prevalence of inadequacy was observed for fat (29·9–47·7 %), dietary fibre (18·1–76·1 %) and salt (97·0–100 %). Inadequate habitual Intake of vitamins and minerals (except Na) was infrequent in elementary-school children, but was observed in junior high-school children, particularly boys. Conclusions School lunches appear to improve total diet quality, particularly Intake of most vitamins and minerals in Japanese children. However, excess Intakes of fat and salt and insufficient Intake of dietary fibre were major problems in this population. The contribution of school lunches to improving the Intakes of these three Nutrients was considered insufficient.
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within and between individual variation in energy and Nutrient Intake in japanese adults effect of age and sex differences on group size and number of records required for adequate dietary assessment
Journal of Epidemiology, 2013Co-Authors: Azusa Fukumoto, Keiko Asakura, Satoshi Sasaki, Kentaro Murakami, Hitomi Okubo, Naoko Hirota, Akiko Notsu, Hidemi Todoriki, Ayako Miura, Mitsuru FukuiAbstract:Background Information on within- and between-individual variation in energy and Nutrient Intake is critical for precisely estimating usual dietary Intake; however, data from Japanese populations are limited.
Gail Rogers - One of the best experts on this subject based on the ideXlab platform.
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association among dietary supplement use Nutrient Intake and mortality among u s adults a cohort study
Annals of Internal Medicine, 2019Co-Authors: Fan Chen, Gail Rogers, Jeffrey B Blumberg, Kenneth Chui, Mengyuan Ruan, Zhilei Shan, Luxian Zeng, Fang Fang ZhangAbstract:Background The health benefits and risks of dietary supplement use are controversial. Objective To evaluate the association among dietary supplement use, levels of Nutrient Intake from foods and supplements, and mortality among U.S. adults. Design Prospective cohort study. Setting NHANES (National Health and Nutrition Examination Survey) data from 1999 to 2010, linked to National Death Index mortality data. Participants 30 899 U.S. adults aged 20 years or older who answered questions on dietary supplement use. Measurements Dietary supplement use in the previous 30 days and Nutrient Intake from foods and supplements. Outcomes included mortality from all causes, cardiovascular disease (CVD), and cancer. Results During a median follow-up of 6.1 years, 3613 deaths occurred, including 945 CVD deaths and 805 cancer deaths. Ever-use of dietary supplements was not associated with mortality outcomes. Adequate Intake (at or above the Estimated Average Requirement or the Adequate Intake level) of vitamin A, vitamin K, magnesium, zinc, and copper was associated with reduced all-cause or CVD mortality, but the associations were restricted to Nutrient Intake from foods. Excess Intake of calcium was associated with increased risk for cancer death (above vs. at or below the Tolerable Upper Intake Level: multivariable-adjusted rate ratio, 1.62 [95% CI, 1.07 to 2.45]; multivariable-adjusted rate difference, 1.7 [CI, -0.1 to 3.5] deaths per 1000 person-years), and the association seemed to be related to calcium Intake from supplements (≥1000 mg/d vs. no use: multivariable-adjusted rate ratio, 1.53 [CI, 1.04 to 2.25]; multivariable-adjusted rate difference, 1.5 [CI, -0.1 to 3.1] deaths per 1000 person-years) rather than foods. Limitations Results from observational data may be affected by residual confounding. Reporting of dietary supplement use is subject to recall bias. Conclusion Use of dietary supplements is not associated with mortality benefits among U.S. adults. Primary funding source National Institutes of Health.
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long term Nutrient Intake and 5 year change in nuclear lens opacities
Archives of Ophthalmology, 2005Co-Authors: Paul F Jacques, Walter C Willett, Susan E Hankinson, Gail Rogers, William H Tung, Allen Taylor, Suzen M Moeller, Jose Ludovico, Leo T ChylackAbstract:Objective To determine if usual Nutrient Intake is related to a 5-year change in the amount of lens nuclear opacification assessed by computer-assisted image analysis. Design A sample of 408 Boston, Mass–area women from the Nurses’ Health Study aged 52 to 74 years at baseline participated in a 5-year study related to nutrition and vision. Usual Nutrient Intake was calculated as the average Intake from 5 food frequency questionnaires that were collected over a 13- to 15-year period before the baseline evaluation of lens nuclear density. Duration of vitamin supplement use before baseline was determined from 7 questionnaires collected during this same period. We assessed the degree of nuclear density (opacification) using computer-assisted image analysis of digital lens images with amount of nuclear density measured as a function of average pixel gray scale, ranging from 0 (clear) to 255 (black). Results Median (range) baseline and follow-up nuclear densities were 44 (19 to 102) and 63 (32 to 213). The median (range) 5-year change in nuclear density was 18 (−29 to 134) and was positively correlated with the amount of opacification at baseline (Spearman correlation coefficient = 0.35; P P trend = .03) and thiamin ( P trend = .04) and duration of vitamin E supplement use ( P trend = .006). Conclusion Our results suggest that long-term use of vitamin E supplements and higher riboflavin and/or thiamin Intake may reduce the progression of age-related lens opacification.
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long term Nutrient Intake and early age related nuclear lens opacities
Archives of Ophthalmology, 2001Co-Authors: Paul F Jacques, Leo T Chylack, Susan E Hankinson, Patricia M Khu, Gail Rogers, Judith Friend, William H Tung, John K Wolfe, Nita Padhye, Walter C WillettAbstract:Objective To assess the relation between usual Nutrient Intake and subsequently diagnosed age-related nuclear lens opacities. Subjects Four hundred seventy-eight nondiabetic women aged 53 to 73 years from the Boston, Mass, area without previously diagnosed cataracts sampled from the Nurses' Health Study cohort. Methods Usual Nutrient Intake was calculated as the average Intake from 5 food frequency questionnaires that were collected during a 13- to 15-year period before the evaluation of lens opacities. The duration of vitamin supplement use was determined from 7 questionnaires collected during this same period. We defined nuclear opacities as a nuclear opalescence grade of 2.5 or higher using the Lens Opacification Classification System III. Results The prevalence of nuclear opacification was significantly lower in the highest Nutrient Intake quintile category relative to the lowest quintile category for vitamin C ( P P = .02), riboflavin ( P = .005), folate ( P = .009), β-carotene ( P = .04), and lutein/zeaxanthin ( P = .03). After adjustment for other Nutrients, only vitamin C Intake remained significantly associated ( P = .003 for trend) with the prevalence of nuclear opacities. The prevalence of nuclear opacities was significantly lower ( P P = .004 for trend), vitamin E ( P = .03 for trend), and multivitamin ( P = .04 for trend) supplements, but only duration of vitamin C supplement use remained significantly associated with nuclear opacities after mutual adjustment for use of vitamin E ( P = .05 for trend) or multivitamin ( P = .02 for trend) supplements. The prevalence of nuclear opacities was significantly lower ( P = .004) for women who used a vitamin C supplement for 10 or more years relative to women who never used vitamin C supplements (odds ratio, 0.36; 95% confidence interval, 0.18-0.72). Plasma measures of vitamins C and E taken at the eye examination were also inversely associated with the prevalence of nuclear opacities. Conclusion These results provide additional evidence that antioxidant Nutrients play a role in the prevention of age-related nuclear lens opacities.
