Obex

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Liliane Peyrin - One of the best experts on this subject based on the ideXlab platform.

  • Stimulatory Effect of Long-Term Hypoxia on the Posterior Part of A2 Noradrenergic Cell Group in Nucleus Tractus Solitarius of Rat
    Advances in Experimental Medicine and Biology, 1993
    Co-Authors: Jean-marc Pequignot, V. Soulier, N. Borghini, Yvette Dalmaz, Jean-marie Cottet-emard, Liliane Peyrin
    Abstract:

    The nucleus tractus solitarius has been demonstrated to receive the primary chemoreceptor afferents of the carotid sinus nerve. The chemosensory fibres terminate in a relatively restricted area which extends caudal to the Obex and includes the commissural nucleus and the medial subnucleus (Donoghue et al., 1984; Housley et al., 1987, Housley and Sinclair, 1988). This region seems to correspond to the anatomic location of an aggregate of noradrenergic neurones that make up the A2 cell group. In fact, the A2 group extends both caudal and rostral to the Obex and, as referred above, only the posterior part could receive the peripheral chemosensory inputs.

Roger A L Dampney - One of the best experts on this subject based on the ideXlab platform.

  • Angiotensin II evokes hypotension and renal sympathoinhibition from a highly restricted region in the nucleus tractus solitarii.
    Brain research, 2005
    Co-Authors: Peter S P Tan, Jason R Potas, Suzanne Killinger, Jouji Horiuchi, Ann K Goodchild, Paul M Pilowsky, Roger A L Dampney
    Abstract:

    Microinjections of low doses (in the femtomolar or low picomolar range) of angiotensin II (Ang II) into the nucleus tractus solitarii (NTS) evoke depressor responses. In this study we have mapped in the rat the precise location of the subregion within the NTS at which Ang II evokes significant sympathoinhibitory and depressor responses. Microinjections of 1 pmol of Ang II evoked large decreases (>or=20% of baseline) in renal sympathetic nerve activity (RSNA), from a highly restricted region in the medial NTS, at or very close to the level 0.2 mm caudal to the Obex. Microinjections of the same dose of Ang II into the commissural or lateral NTS at the same rostrocaudal level, or into the medial and lateral NTS at the level of the Obex evoked significantly smaller sympathoinhibitory responses, while microinjections into more rostral or caudal levels of the NTS evoked significant sympathoinhibitory responses even less frequently. In most cases (71%), the sympathoinhibitory responses were accompanied by depressor responses, the magnitudes of which were also greater within the medial NTS at the level 0.2 mm caudal to Obex, as compared to the surrounding subregions. The results demonstrate that the cardiovascular effects of Ang II in the NTS are highly site-specific. Taken together with previous studies, the results also indicate that the neurons in the NTS that mediate the Ang II-evoked sympathoinhibition are a discrete subgroup of the population of sympathoinhibitory neurons within the nucleus.

Albert P. Benetti - One of the best experts on this subject based on the ideXlab platform.

  • Caudal portions of the spinal trigeminal complex are necessary for autonomic responses and display Fos-like immunoreactivity after corneal stimulation in the cat
    Brain Research, 1994
    Co-Authors: David A. Bereiter, Charles B. Hathaway, Albert P. Benetti
    Abstract:

    Corneal input to the spinal trigeminal nucleus (Vsp) was assessed by examining Fos-like immunoreactivity (Fos-LI) after chemical irritant stimulation by mustard oil in chloralose-anesthetized cats. The distribution of Fos-LI within the ipsilateral Vsp was bimodal: a dominant group of cells within the superficial laminae at caudal levels of subnucleus caudalis and a second group of cells within the ventrolateral pole of Vsp at Obex levels and within the adjacent interstitial islands. Few Fos-positive cells were seen within the Vsp rostral to the mid-portion of subnucleus interpolaris or within the contralateral Vsp. To assess the involvement of caudal portions of the Vsp in mediating the adrenal and autonomic responses to corneal stimulation, mustard oil was applied before and after lidocaine blockade of the Vsp at Obex levels in a second group of cats. Corneal stimulation alone increased significantly (P < 0.001) the adrenal secretion of catecholamines, adrenal blood flow, mean arterial pressure and heart rate. With the exception of heart rate, the adrenal and autonomic responses to mustard oil were greatly attenuated or abolished by lidocaine blockade of the ipsilateral Vsp at the level of the Obex, a region that displayed a high number of Fos-positive cells after corneal stimulation. These results indicate that neurons within the Vsp at or more caudal than the level of the Obex process chemical irritant input from the cornea and are necessary for corneal-evoked changes in adrenal and autonomic function.

P.l. Brien - One of the best experts on this subject based on the ideXlab platform.

  • Fatiguing isometric contraction of hind-limb muscles results in the release of immunoreactive neurokinins from sites in the rostral medulla in the anesthetized cat.
    Neuropeptides, 1995
    Co-Authors: Carole A. Williams, R. Gopalan, P.l. Nichols, P.l. Brien
    Abstract:

    Abstract Antibody-coated microprobes were used to determine whether immunoreactive neurokinins (irNK) were released from sites in the brainstem during fatiguing isometric contractions of the triceps surae muscles in cats anesthetized with α-chloralose. Contractions were generated by stimulating the tibial nerve using a microprocessor-controlled stimulator. Microprobes were inserted into the periaqueductal grey (P 0.5–1.0 mm) or the medullary brainstem (either 3.0 or 3.5 mm rostral to the Obex) prior to, during and following fatiguing contractions. No release of irNK was detected from the periaqueductal grey as a result of fatiguing isometric contractions. When probes were inserted 3.0 mm rostal to the Obex, a basal release of irNK was detected from the medulla but this was inhibited during isometric contractions from sites corresponding to the lateral tegmental field. When probes were inserted into the more rostal site in the medulla (3.5 mm rostral to the Obex), irNK were released in response to contractions from sites corresponding to lateral reticular nucleus, ventral regions of the nucleus tractus solitarius and the medial vestibular nucleus. No irNK were released from this site (3.5 mm rostral to Obex) either during passive leg flexing, during nerve stimulation following gallamine injection and muscle paralysis or during stimulation of the central end of the cut tibial nerve. These results demonstrate that neurokinins are released from discrete sites in the medulla in response to fatiguing muscle contractions and suggest that tachykinin neurons may be a component of the pathways regulating blood pressure during ergoreceptor activation.

Eiji Okamoto - One of the best experts on this subject based on the ideXlab platform.

  • Networking Workshops - BlueSnarf revisited: Obex FTP service directory traversal
    NETWORKING 2011 Workshops, 2011
    Co-Authors: Alberto Moreno, Eiji Okamoto
    Abstract:

    As mobile operating systems reach the same level of complexity of computer operating systems, these may be affected by the same vulnerabilities and may be subject to the same kind of attacks. Bluetooth provides connectivity to a mobile phone but this network can also be used as a channel to deploy attacks and access its resources, such as personal information, confidential files or the possibility of making phone calls and consume the user's balance. When the first attacks to early Bluetooth mobile phones came up, manufacturers were forced to raise awareness about Bluetooth and make improvements in the security of the implementation. In spite of the improvements, we introduce a multi-platform vulnerability for mobile phones that allows a remote attacker to list arbitrary directories, and read and write arbitrary files via Bluetooth. Our experience shows that the attack can be performed in a real environment and it may lead to data theft.

  • bluesnarf revisited Obex ftp service directory traversal
    International Conference on Networking, 2011
    Co-Authors: Alberto Moreno, Eiji Okamoto
    Abstract:

    As mobile operating systems reach the same level of complexity of computer operating systems, these may be affected by the same vulnerabilities and may be subject to the same kind of attacks. Bluetooth provides connectivity to a mobile phone but this network can also be used as a channel to deploy attacks and access its resources, such as personal information, confidential files or the possibility of making phone calls and consume the user's balance. When the first attacks to early Bluetooth mobile phones came up, manufacturers were forced to raise awareness about Bluetooth and make improvements in the security of the implementation. In spite of the improvements, we introduce a multi-platform vulnerability for mobile phones that allows a remote attacker to list arbitrary directories, and read and write arbitrary files via Bluetooth. Our experience shows that the attack can be performed in a real environment and it may lead to data theft.