The Experts below are selected from a list of 2445 Experts worldwide ranked by ideXlab platform
Mohammadreza R Khalili - One of the best experts on this subject based on the ideXlab platform.
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Effectiveness of Topical Onion Extract Gel in the Cosmetic Appearance of Blepharoplasty Scar.
The Journal of clinical and aesthetic dermatology, 2018Co-Authors: Naser Owji, Behzad Khademi, Mohammadreza R KhaliliAbstract:Objectives: Topical Onion Extract gel is commonly used in commercial anti-scar medications. The purpose of this study was to evaluate the effectiveness of topical Onion Extract gel on the appearance of blepharoplasty scars and to compare the results of its use to those of petroleum jelly. Design: The participants enrolled in this prospective, double-blind study were randomly treated with either topical Onion Extract gel or petroleum jelly. The products were applied twice daily for two months following suture removal. Patients were evaluated objectively using the Manchester Scar Scale at the end of treatment. Six months after surgery, a follow-up phone interview was conducted. Setting: The study was carried out in the Khalili and Dastghaib Hospitals in Shiraz, Iran. Participants: Out of 43 participants who had upper blepharoplasty, 26 patients completed the follow up. Measurements: The Manchester Scar Scale evaluates five different characteristics of scar: color (score: 1-4), distortion (score: 1-4), contour (score: 1-4), texture (score: 1-4), and transparency (score: 1-2). A visual analogue scale (VAS) was also used to quantify the overall scar appearance on a range of 0 to 10 (with the highest number indicating the worst appearance). The scores for the five different parameters and the VAS were calculated and compared. Results: There was no statistically significant difference in overall cosmetic appearance objectively and/or subjectively between the two sides (p value: 0.25). Conclusion: Topical Onion Extract gel was ineffective in improving overall blepharoplasty scar appearance when compared with a petroleum-based ointment.
Zafer Kurumlu - One of the best experts on this subject based on the ideXlab platform.
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an open randomized controlled comparative study of the combined effect of intralesional triamcinolone acetonide and Onion Extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids
Dermatologic Surgery, 2008Co-Authors: Erol Koc, Ercan Arca, Baris Surucu, Zafer KurumluAbstract:BACKGROUND Various treatment regimens have been used in scars. The literature offers little consensus about appropriate therapy. OBJECTIVE To compare intralesional triamcinolone acetonide (TAC) alone or combined with Onion Extract in keloidal and hypertrophic scars. MATERIALS AND METHODS Fourteen patients were treated with intralesional TAC and Onion Extract gel, and 13 patients were treated with intralesional TAC alone. Findings were recorded and graded at each visit (weeks 0, 4, 12, and 20). The scores before treatment and at week 20 were compared. RESULTS Twenty-seven patients [17 men (63%) and 10 women (37%) aged 15 to 73 (average age 28.1±11.7)] were enrolled in the study. At baseline, the difference in the two treatment groups was not statistically significant (p>.05). At week 20, there was statistically significant improvement in both treatment groups (p<.05). TAC with Onion Extract was more effective than TAC alone in terms of pain-sensitiveness, itching, and elevation but not in erythema and induration. Treatment was well tolerated, without any adverse effect. CONCLUSION Treatment with intralesional TAC and Onion Extract and TAC alone were effective. Combined with Onion Extract gel, intralesional TAC appears to be superior to TAC alone in the treatment of keloids and hypertrophic scars.
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An open, randomized, controlled, comparative study of the combined effect of intralesional triamcinolone acetonide and Onion Extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2008Co-Authors: Erol Koc, Ercan Arca, Baris Surucu, Zafer KurumluAbstract:BACKGROUND Various treatment regimens have been used in scars. The literature offers little consensus about appropriate therapy. OBJECTIVE To compare intralesional triamcinolone acetonide (TAC) alone or combined with Onion Extract in keloidal and hypertrophic scars. MATERIALS AND METHODS Fourteen patients were treated with intralesional TAC and Onion Extract gel, and 13 patients were treated with intralesional TAC alone. Findings were recorded and graded at each visit (weeks 0, 4, 12, and 20). The scores before treatment and at week 20 were compared. RESULTS Twenty-seven patients [17 men (63%) and 10 women (37%) aged 15 to 73 (average age 28.1±11.7)] were enrolled in the study. At baseline, the difference in the two treatment groups was not statistically significant (p>.05). At week 20, there was statistically significant improvement in both treatment groups (p
Vasanop Vachiramon - One of the best experts on this subject based on the ideXlab platform.
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Effectiveness of Onion Extract Gel on Surgical Scars in Asians
Dermatology research and practice, 2012Co-Authors: Kumutnart Chanprapaph, Somsak Tanrattanakorn, Penpun Wattanakrai, Pranee Wongkitisophon, Vasanop VachiramonAbstract:Background. Onion Extracts have been shown in vitro to accelerate wound healing. Results from clinical studies on surgical scars in Caucasians were disappointing. The aim of this study is to evaluate the effectiveness of Onion Extract gel in improving the cosmetic and symptoms of surgical scars in Asians. Patients/Methods. Twenty Asians who had new Pfannenstiel’s cesarean section scars were recruited in this prospective double-blinded, split-scar study. Each side was randomly assigned treatment with Onion Extract gel or placebo at 7 days after surgery. The product was applied three times daily for 12 weeks. Subjects were evaluated at baseline and 4th and 12th weeks. Scar redness was assessed by calorimeter, scar height and pliability were assessed by blinded investigators, and scar symptoms and overall cosmetic improvement were assessed by subjects. Results. Sixteen subjects completed the study. A statistically significant difference between two sides of scar in terms of scar height and scar symptoms was found. There was no statistically significant difference in scar redness, scar pliability, and overall cosmetic appearance between two sides. Conclusions. The early use of topical 12% Onion Extract gel on Pfannenstiel’s cesarean section scar in Asians resulted in the improvement of scar height and scar symptoms.
Bilsev Ince - One of the best experts on this subject based on the ideXlab platform.
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The utility of Onion Extract gel containing topical allantoin and heparin after surgical treatment of upper extremity burn scars
Hand and Microsurgery, 2014Co-Authors: Mehmet İhsan Okur, Alpagan Mustafa Yildirim, Bilsev InceAbstract:Background: The development of hypertrophic scars after burns can lead to esthetic as well as functional disorders. The aim of the study was to determine the functional and cosmetic effects of Contractubex® (Onion Extract, heparin, allantoin) gel applied in burn scar patients after surgery for scar excision and skin grafts. Patients and Methods: The study included seven male patients who presented to our clinic between 2005 and 2012 for the treatment of hypertrophic burn scar and were administered either single or combined medical hypertrophic scar treatments. Patients who had scars on the right upper extremity were included in group 1 and those with left upper extremity scars in group 2. In group 1, all scars were excised and closed with medium thickness skin graft. After surgery, the Onion Extract gel was applied to the right upper extremities. In group 2, only surgical treatment was applied. The results were evaluated with Vancouver scar scale. Results: Vascularity, flexibility, and height of the scars improved significantly in both groups. In addition, hyperpigmentation was observed on the skin grafts of all patients. Scar flexibility was less often observed in patients’ left upper extremities. However, no statistical difference between groups 1 and 2 was found. Conclusion: Although no significant difference was obtained with Contractubex gel treatment in this study, cosmetic and functional success can be achieved through excision of the scar and use of medium thickness skin graft in patients with upper extremity hypertrophic burn scarring that is resistant to conservative treatments.
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THE UTILITY OF Onion Extract GEL CONTAINING TOPICAL ALLANTOIN AND HEPARIN AFTER SURGICAL TREATMENT OF UPPER EXTREMITY BURN SCAR
Hand and Microsurgery, 2014Co-Authors: Mehmet Okur, Alpagan Yildirim, Bilsev InceAbstract:Background: The development of hypertrophic scars after burns can lead to esthetic as well as functional disorders. The aim of the study was to determine the functional and cosmetic effects of Contractubex and reg; (Onion Extract, heparin, allantoin) gel applied in burn scar patients after surgery for scar excision and skin grafts. Patients and Methods: The study included seven male patients who presented to our clinic between 2005 and 2012 for the treatment of hypertrophic burn scar and were administered either single or combined medical hypertrophic scar treatments. Patients who had scars on the right upper extremity were included in group 1 and those with left upper extremity scars in group 2. In group 1, all scars were excised and closed with medium thickness skin graft. After surgery, the Onion Extract gel was applied to the right upper extremities. In group 2, only surgical treatment was applied. The results were evaluated with Vancouver scar scale. Results: Vascularity, flexibility, and height of the scars improved significantly in both groups. In addition, hyperpigmentation was observed on the skin grafts of all patients. Scar flexibility was less often observed in patients' left upper extremities. However, no statistical difference between groups 1 and 2 was found. Conclusion: Although no significant difference was obtained with Contractubex gel treatment in this study, cosmetic and functional success can be achieved through excision of the scar and use of medium thickness skin graft in patients with upper extremity hypertrophic burn scarring that is resistant to conservative treatments. [Hand Microsurg 2014; 3(3.000): 74-79
Naser Owji - One of the best experts on this subject based on the ideXlab platform.
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Effectiveness of Topical Onion Extract Gel in the Cosmetic Appearance of Blepharoplasty Scar.
The Journal of clinical and aesthetic dermatology, 2018Co-Authors: Naser Owji, Behzad Khademi, Mohammadreza R KhaliliAbstract:Objectives: Topical Onion Extract gel is commonly used in commercial anti-scar medications. The purpose of this study was to evaluate the effectiveness of topical Onion Extract gel on the appearance of blepharoplasty scars and to compare the results of its use to those of petroleum jelly. Design: The participants enrolled in this prospective, double-blind study were randomly treated with either topical Onion Extract gel or petroleum jelly. The products were applied twice daily for two months following suture removal. Patients were evaluated objectively using the Manchester Scar Scale at the end of treatment. Six months after surgery, a follow-up phone interview was conducted. Setting: The study was carried out in the Khalili and Dastghaib Hospitals in Shiraz, Iran. Participants: Out of 43 participants who had upper blepharoplasty, 26 patients completed the follow up. Measurements: The Manchester Scar Scale evaluates five different characteristics of scar: color (score: 1-4), distortion (score: 1-4), contour (score: 1-4), texture (score: 1-4), and transparency (score: 1-2). A visual analogue scale (VAS) was also used to quantify the overall scar appearance on a range of 0 to 10 (with the highest number indicating the worst appearance). The scores for the five different parameters and the VAS were calculated and compared. Results: There was no statistically significant difference in overall cosmetic appearance objectively and/or subjectively between the two sides (p value: 0.25). Conclusion: Topical Onion Extract gel was ineffective in improving overall blepharoplasty scar appearance when compared with a petroleum-based ointment.
