The Experts below are selected from a list of 28752 Experts worldwide ranked by ideXlab platform
Molly Craxton - One of the best experts on this subject based on the ideXlab platform.
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A manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes - an Open Access Resource for neuroscience and evolutionary biology
BMC Genomics, 2010Co-Authors: Molly CraxtonAbstract:Background Synaptotagmin proteins were first identified in nervous tissue, residing in synaptic vesicles. Synaptotagmins were subsequently found to form a large family, some members of which play important roles in calcium triggered exocytic events. These members have been investigated intensively, but other family members are not well understood, making it difficult to grasp the meaning of family membership in functional terms. Further difficulty arises as families are defined quite legitimately in different ways: by common descent or by common possession of distinguishing features. One definition does not necessarily imply the other. The evolutionary range of genome sequences now available, can shed more light on synaptotagmin gene phylogeny and clarify family relationships. The aim of compiling this Open Access collection of synaptotagmin and synaptotagmin-like sequences, is that its use may lead to greater understanding of the biological function of these proteins in an evolutionary context. Results 46 metazoan genomes were examined and their complement of Syt , Esyt , Rph3a , Rph3al , Doc2 and Dblc2 genes identified. All of the sequences were compared, named, then examined in detail. Esyt genes were formerly named Fam62 . The species in this collection are Trichoplax , Nematostella , Capitella , Helobdella , Lottia , Ciona , Strongylocentrotus , Branchiostoma , Ixodes , Daphnia , Acyrthosiphon , Tribolium , Nasonia , Apis , Anopheles , Drosophila , Caenorhabditis , Takifugu , Tetraodon , Gasterosteus , Oryzias , Danio , Xenopus , Anolis , Gallus , Taeniopygia , Ornithorhynchus , Monodelphis , Mus and Homo . All of the data described in this paper is available as additional files. Conclusions Only a subset of synaptotagmin proteins appear able to function as calcium triggers. Syt1, Syt7 and Syt9 are ancient conserved synaptotagmins of this type. Some animals carry extensive repertoires of synaptotagmin genes. Other animals of no less complexity, carry only a small repertoire. Current understanding does not explain why this is so. The biological roles of many synaptotagmins remain to be understood. This collection of genes offers prospects for fruitful speculation about the functional roles of the synaptotagmin repertoires of different animals and includes a great range of biological complexity. With reference to this gene collection, functional relationships among Syt , Esyt , Rph3a , Rph3al , Doc2 and Dblc2 genes, which encode similar proteins, can better be assessed in future.
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A manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes - an Open Access Resource for neuroscience and evolutionary biology
BMC genomics, 2010Co-Authors: Molly CraxtonAbstract:Background Synaptotagmin proteins were first identified in nervous tissue, residing in synaptic vesicles. Synaptotagmins were subsequently found to form a large family, some members of which play important roles in calcium triggered exocytic events. These members have been investigated intensively, but other family members are not well understood, making it difficult to grasp the meaning of family membership in functional terms. Further difficulty arises as families are defined quite legitimately in different ways: by common descent or by common possession of distinguishing features. One definition does not necessarily imply the other. The evolutionary range of genome sequences now available, can shed more light on synaptotagmin gene phylogeny and clarify family relationships. The aim of compiling this Open Access collection of synaptotagmin and synaptotagmin-like sequences, is that its use may lead to greater understanding of the biological function of these proteins in an evolutionary context.
James E Wilen - One of the best experts on this subject based on the ideXlab platform.
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markets and rent dissipation in regulated Open Access fisheries
Journal of Environmental Economics and Management, 2005Co-Authors: Frances R Homans, James E WilenAbstract:Abstract Using a model of regulated Open Access Resource use with markets, we illustrate the potential complexity of interactions between markets, product quality, excess effort, and regulatory behavior in fisheries. Our model assumes two product types, one of which is processed and storable. The model describes the equilibrium that results when effort responds to Open Access incentives and when regulators respond to effort growth by mitigating its potential harmful effects on biomass safety. We use numerical simulations to demonstrate a mechanism by which market growth leads to the diversion of raw inputs into the inherently inferior market. The result is a scenario in which rents are dissipated not only because excessive inputs raise costs, but also because inferior product types reduce revenues. We conclude with an illustrative decomposition of rent gains into revenue and cost savings gains from rationalizing a hypothetical fishery, demonstrating the potential significance of market-side rents.
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a model of regulated Open Access Resource use
Journal of Environmental Economics and Management, 1997Co-Authors: Frances R Homans, James E WilenAbstract:Abstract This paper develops a model of regulated Open Access Resource exploitation. The regulatory model assumes that regulators are goal oriented, choosing target harvest levels according to a safe stock concept. These harvest quotas are implemented by setting season lengths, conditioned on the industry fishing capacity. The industry enters until rents are dissipated, conditioned on season length regulations. Harvest levels, fishing capacity, season length, and biomass are determined jointly. Using parameter estimates from the long-regulated North Pacific Halibut fishery, predictions of these variables from the regulated Open Access model are compared to predictions that arise from the Gordon model.
Frances R Homans - One of the best experts on this subject based on the ideXlab platform.
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markets and rent dissipation in regulated Open Access fisheries
Journal of Environmental Economics and Management, 2005Co-Authors: Frances R Homans, James E WilenAbstract:Abstract Using a model of regulated Open Access Resource use with markets, we illustrate the potential complexity of interactions between markets, product quality, excess effort, and regulatory behavior in fisheries. Our model assumes two product types, one of which is processed and storable. The model describes the equilibrium that results when effort responds to Open Access incentives and when regulators respond to effort growth by mitigating its potential harmful effects on biomass safety. We use numerical simulations to demonstrate a mechanism by which market growth leads to the diversion of raw inputs into the inherently inferior market. The result is a scenario in which rents are dissipated not only because excessive inputs raise costs, but also because inferior product types reduce revenues. We conclude with an illustrative decomposition of rent gains into revenue and cost savings gains from rationalizing a hypothetical fishery, demonstrating the potential significance of market-side rents.
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a model of regulated Open Access Resource use
Journal of Environmental Economics and Management, 1997Co-Authors: Frances R Homans, James E WilenAbstract:Abstract This paper develops a model of regulated Open Access Resource exploitation. The regulatory model assumes that regulators are goal oriented, choosing target harvest levels according to a safe stock concept. These harvest quotas are implemented by setting season lengths, conditioned on the industry fishing capacity. The industry enters until rents are dissipated, conditioned on season length regulations. Harvest levels, fishing capacity, season length, and biomass are determined jointly. Using parameter estimates from the long-regulated North Pacific Halibut fishery, predictions of these variables from the regulated Open Access model are compared to predictions that arise from the Gordon model.
Sara C. Pryor - One of the best experts on this subject based on the ideXlab platform.
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An overview of data for wake model evaluation in the Virtual Wakes Laboratory
Applied Energy, 2013Co-Authors: Rebecca Jane Barthelmie, Sara C. PryorAbstract:Improved prognostic models of wind turbine wakes are essential to improved design of offshore wind farms to maximized power production and minimize turbine fatigue loading. This paper describes the Virtual Wake Laboratory, an online Open Access Resource that provides meteorological and wind farm data for use in wake characterization and wake model evaluation exercises. Specific examples of the types of analyses that can be conducted using these data are given, along with recommendations regarding appropriate metrics to be applied and considerations for wake model evaluation.
Gao Shu-qin - One of the best experts on this subject based on the ideXlab platform.
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Open Access Resource and Current Situation in Library and Information Science
Information Sciences, 2007Co-Authors: Gao Shu-qinAbstract:This article gives a detailed introduction about four types of Open Access Resource which have been known by the author in order to popularize Open Access Resource in Library and Information Science.
