The Experts below are selected from a list of 51 Experts worldwide ranked by ideXlab platform
Maggio Roberto - One of the best experts on this subject based on the ideXlab platform.
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Dichlorodiphenyltrichloroethane, an old pesticide with a new mechanism of toxicity
2018Co-Authors: Pietrantoni Ilaria, Rossi Mario, Scarselli Marco, Fasciani Irene, Marampon Francesco, Maggio RobertoAbstract:Dichlorodiphenyltrichloroethane (DDT) is an Organochlorine Derivative known for its detrimental effect on human health. It was abundantly used as a pesticide and finally banned in many countries for its toxicity. Because of its extremely long half-life (up to 10 years), DDT is still blamed to cause health problems, due to the accumulation in the environment. We have previously shown that in vitro exposure to DDT causes severe membrane shedding with the release of vesicular organelles such as exosomes and/or ectosomes. A large body of evidence has shown that these vesicles, other than being directly involved in physiological exchanges of cellular materials, are implicated in the pathogenesis of several diseases such as viral and neurodegenerative diseases as well as tumorigenesis. In this short review, we discuss how the increased release of extracellular vesicles could explain the enhanced risk of diseases in patients exposed to Organochlorine Derivatives such as DDT
Pietrantoni Ilaria - One of the best experts on this subject based on the ideXlab platform.
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Dichlorodiphenyltrichloroethane, an old pesticide with a new mechanism of toxicity
2018Co-Authors: Pietrantoni Ilaria, Rossi Mario, Scarselli Marco, Fasciani Irene, Marampon Francesco, Maggio RobertoAbstract:Dichlorodiphenyltrichloroethane (DDT) is an Organochlorine Derivative known for its detrimental effect on human health. It was abundantly used as a pesticide and finally banned in many countries for its toxicity. Because of its extremely long half-life (up to 10 years), DDT is still blamed to cause health problems, due to the accumulation in the environment. We have previously shown that in vitro exposure to DDT causes severe membrane shedding with the release of vesicular organelles such as exosomes and/or ectosomes. A large body of evidence has shown that these vesicles, other than being directly involved in physiological exchanges of cellular materials, are implicated in the pathogenesis of several diseases such as viral and neurodegenerative diseases as well as tumorigenesis. In this short review, we discuss how the increased release of extracellular vesicles could explain the enhanced risk of diseases in patients exposed to Organochlorine Derivatives such as DDT
Rossi Mario - One of the best experts on this subject based on the ideXlab platform.
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Dichlorodiphenyltrichloroethane, an old pesticide with a new mechanism of toxicity
2018Co-Authors: Pietrantoni Ilaria, Rossi Mario, Scarselli Marco, Fasciani Irene, Marampon Francesco, Maggio RobertoAbstract:Dichlorodiphenyltrichloroethane (DDT) is an Organochlorine Derivative known for its detrimental effect on human health. It was abundantly used as a pesticide and finally banned in many countries for its toxicity. Because of its extremely long half-life (up to 10 years), DDT is still blamed to cause health problems, due to the accumulation in the environment. We have previously shown that in vitro exposure to DDT causes severe membrane shedding with the release of vesicular organelles such as exosomes and/or ectosomes. A large body of evidence has shown that these vesicles, other than being directly involved in physiological exchanges of cellular materials, are implicated in the pathogenesis of several diseases such as viral and neurodegenerative diseases as well as tumorigenesis. In this short review, we discuss how the increased release of extracellular vesicles could explain the enhanced risk of diseases in patients exposed to Organochlorine Derivatives such as DDT
Scarselli Marco - One of the best experts on this subject based on the ideXlab platform.
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Dichlorodiphenyltrichloroethane, an old pesticide with a new mechanism of toxicity
2018Co-Authors: Pietrantoni Ilaria, Rossi Mario, Scarselli Marco, Fasciani Irene, Marampon Francesco, Maggio RobertoAbstract:Dichlorodiphenyltrichloroethane (DDT) is an Organochlorine Derivative known for its detrimental effect on human health. It was abundantly used as a pesticide and finally banned in many countries for its toxicity. Because of its extremely long half-life (up to 10 years), DDT is still blamed to cause health problems, due to the accumulation in the environment. We have previously shown that in vitro exposure to DDT causes severe membrane shedding with the release of vesicular organelles such as exosomes and/or ectosomes. A large body of evidence has shown that these vesicles, other than being directly involved in physiological exchanges of cellular materials, are implicated in the pathogenesis of several diseases such as viral and neurodegenerative diseases as well as tumorigenesis. In this short review, we discuss how the increased release of extracellular vesicles could explain the enhanced risk of diseases in patients exposed to Organochlorine Derivatives such as DDT
Fasciani Irene - One of the best experts on this subject based on the ideXlab platform.
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Dichlorodiphenyltrichloroethane, an old pesticide with a new mechanism of toxicity
2018Co-Authors: Pietrantoni Ilaria, Rossi Mario, Scarselli Marco, Fasciani Irene, Marampon Francesco, Maggio RobertoAbstract:Dichlorodiphenyltrichloroethane (DDT) is an Organochlorine Derivative known for its detrimental effect on human health. It was abundantly used as a pesticide and finally banned in many countries for its toxicity. Because of its extremely long half-life (up to 10 years), DDT is still blamed to cause health problems, due to the accumulation in the environment. We have previously shown that in vitro exposure to DDT causes severe membrane shedding with the release of vesicular organelles such as exosomes and/or ectosomes. A large body of evidence has shown that these vesicles, other than being directly involved in physiological exchanges of cellular materials, are implicated in the pathogenesis of several diseases such as viral and neurodegenerative diseases as well as tumorigenesis. In this short review, we discuss how the increased release of extracellular vesicles could explain the enhanced risk of diseases in patients exposed to Organochlorine Derivatives such as DDT