The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
M Jashika - One of the best experts on this subject based on the ideXlab platform.
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juvenile psammomatoid Ossifying Fibroma a review
Oral Oncology, 2011Co-Authors: Sachin C Sarode, Gargi S Sarode, Pushkar Waknis, Anuprita Patil, M JashikaAbstract:In WHO classification of odontogenic tumors (2005), juvenile Ossifying Fibroma (JOF) is divided into juvenile psammomatoid Ossifying Fibroma (JPOF) and juvenile trabecular Ossifying Fibroma (JTOF). JPOF has been distinguished because of its location, clinical behavior, and age of occurrence. It is generally seen in younger age group and the most common site is paranasal sinuses, orbits, and fronto-ethmoidal complex. Radiologically, the internal structure can be radiolucent, mixed, or radiopaque, depending on the degree of calcification and extent of the cystic changes. Histologically, it is characterized by a densely cellular fibrous stroma interspersed with numerous psammoma bodies. The treatment is "en bloc" surgical excision while in case of intracranial extension, tumor removal may need a combination of neurosurgical and transfacial approach. Malignant transformation and metastasis has not been reported but recurrence is common. The purpose of this narrative review article is to discuss the various aspects of JPOF reported in the English medical literature.
Rania H. Younis - One of the best experts on this subject based on the ideXlab platform.
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Juvenile Trabecular Ossifying Fibroma.
Head and neck pathology, 2017Co-Authors: Ahmed S. Sultan, Michael K. Schwartz, John F. Caccamese, John C. Papadimitriou, John Basile, Robert D. Foss, Rania H. YounisAbstract:Benign fibro-osseous lesions within the maxillofacial region represent a heterogeneous group of benign entities with overlapping histologic features. Ossifying Fibroma, the rarest of these entities, represents a true neoplasm. Juvenile Ossifying Fibroma (JOF) is considered an aggressive rapidly growing sub-type. It tends to occur in the first or second decades of life. Based on histological and clinical features it can further be classified into two variants, namely juvenile trabecular Ossifying Fibroma (JTOF) and juvenile psammomatoid Ossifying Fibroma (JPOF). JTOF features a proliferation of cellular fibroblastic tissue admixed with woven bone trabeculae with varying histologic presentations. Correlation with clinical and radiographic features is essential to differentiate it from other fibro-osseous lesions. A case of JTOF of the mandible is exemplified in this Sine Qua Non Radiology-Pathology article.
Bradley F. Marple - One of the best experts on this subject based on the ideXlab platform.
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Ossifying Fibroma of the nose and paranasal sinuses.
International forum of allergy & rhinology, 2012Co-Authors: R. Peter Manes, Matthew W. Ryan, Pete S. Batra, Dianne B. Mendelsohn, Yisheng V. Fang, Bradley F. MarpleAbstract:Background The purpose of this work was to perform a systematic review regarding Ossifying Fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical differences between the multiple variants. A search of the U.S. National Library of Medicine (PubMed) database was performed for the non–Medical Subject Heading (MeSH) search term “Ossifying Fibroma.” The bibliographies of the retrieved manuscripts were searched to identify additional potentially relevant articles. Finally, textbooks of head and neck pathology were searched to identify peer-reviewed literature that addresses the histopathology of Ossifying Fibroma and its variants. Abstracts were screened by 2 of the authors to identify reports of Ossifying Fibroma lesions (and its variants) that involved the paranasal sinuses. Extracted data from case reports or case series included the clinical presentation, age, gender, site of involvement, surgical approach, treatment outcome, follow-up period, and recurrence rate. Information derived from cases is summarized in tables, and simple descriptive statistics were applied to the data. A total of 137 distinct patients were identified in 103 reports. Extracted data did not show any appreciable difference in clinical presentation or outcomes. Data on recurrence of these lesions was often limited by a lack of follow-up. Although differentiation between the subtypes of Ossifying Fibroma can be made histologically, and a diverse nomenclature exists, there does not appear to be any overriding clinical significance to the histopathologic differentiation of OF variants. Methods A search of the U.S. National Library of Medicine (PubMed) database was performed for the non–Medical Subject Heading (MeSH) search term “Ossifying Fibroma.” The bibliographies of the retrieved manuscripts were searched to identify additional potentially relevant articles. Finally, textbooks of head and neck pathology were searched to identify peer-reviewed literature that addresses the histopathology of Ossifying Fibroma and its variants. Abstracts were screened by 2 of the authors to identify reports of Ossifying Fibroma lesions (and its variants) that involved the paranasal sinuses. Extracted data from case reports or case series included the clinical presentation, age, gender, site of involvement, surgical approach, treatment outcome, follow-up period, and recurrence rate. Information derived from cases is summarized in tables, and simple descriptive statistics were applied to the data. A total of 137 distinct patients were identified in 103 reports. Extracted data did not show any appreciable difference in clinical presentation or outcomes. Data on recurrence of these lesions was often limited by a lack of follow-up. Although differentiation between the subtypes of Ossifying Fibroma can be made histologically, and a diverse nomenclature exists, there does not appear to be any overriding clinical significance to the histopathologic differentiation of OF variants. Results A total of 137 distinct patients were identified in 103 reports. Extracted data did not show any appreciable difference in clinical presentation or outcomes. Data on recurrence of these lesions was often limited by a lack of follow-up. Although differentiation between the subtypes of Ossifying Fibroma can be made histologically, and a diverse nomenclature exists, there does not appear to be any overriding clinical significance to the histopathologic differentiation of OF variants. Conclusion Although differentiation between the subtypes of Ossifying Fibroma can be made histologically, and a diverse nomenclature exists, there does not appear to be any overriding clinical significance to the histopathologic differentiation of OF variants.
G. R. C. Baker Grc - One of the best experts on this subject based on the ideXlab platform.
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Review of lateral orbital wall Ossifying Fibroma.
Orbit (Amsterdam Netherlands), 2010Co-Authors: M. J. Wakefield, A. H. Ross, E. M. Damato, S. M. Salvi, G. R. C. Baker GrcAbstract:Significant histological overlap exists between fibro-osseous lesions and diagnosis is made on a clinicopathological basis. Ossifying Fibroma is a benign fibro-osseous neoplasm of the jaw and craniofacial complex that has generated a degree of controversy regarding diagnosis and classification, especially with respect to the psammomatoid variant. Orbital lesions mainly arise from the paranasal sinuses affecting the medial or inferior orbital wall. Lateral orbital wall Ossifying Fibroma is, therefore, a rare condition with only a single previous case report. We present a second case of lateral orbital wall Ossifying Fibroma and a review of the associated literature.
Sachin C Sarode - One of the best experts on this subject based on the ideXlab platform.
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juvenile psammomatoid Ossifying Fibroma a review
Oral Oncology, 2011Co-Authors: Sachin C Sarode, Gargi S Sarode, Pushkar Waknis, Anuprita Patil, M JashikaAbstract:In WHO classification of odontogenic tumors (2005), juvenile Ossifying Fibroma (JOF) is divided into juvenile psammomatoid Ossifying Fibroma (JPOF) and juvenile trabecular Ossifying Fibroma (JTOF). JPOF has been distinguished because of its location, clinical behavior, and age of occurrence. It is generally seen in younger age group and the most common site is paranasal sinuses, orbits, and fronto-ethmoidal complex. Radiologically, the internal structure can be radiolucent, mixed, or radiopaque, depending on the degree of calcification and extent of the cystic changes. Histologically, it is characterized by a densely cellular fibrous stroma interspersed with numerous psammoma bodies. The treatment is "en bloc" surgical excision while in case of intracranial extension, tumor removal may need a combination of neurosurgical and transfacial approach. Malignant transformation and metastasis has not been reported but recurrence is common. The purpose of this narrative review article is to discuss the various aspects of JPOF reported in the English medical literature.
