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J. F. Lonneux - One of the best experts on this subject based on the ideXlab platform.
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field efficacy of moxidectin 0 5 pour on against chorioptes bOvis damalinia bOvis linognathus vituli and psoroptes Ovis in naturally infected cattle
Veterinary Parasitology, 1996Co-Authors: Bertrand Losson, J. F. LonneuxAbstract:Field efficacy of a pour-on formulation of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bOvis, Damalinia bOvis, Linognathus vituli and Psoroptes Ovis. In trial 1, two experimental groups of cattle naturally infested with P. Ovis were formed. Group 1 animals remained as untreated controls whereas Group 2 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg-1 bw. Efficacy was assessed by (a) taking skin samples from each animal on days -4, 7, 14, 21, 28, 42 and 56 post treatment (PT) and observing the numbers of viable P. Ovis mites and (b) clinical examination of animals on days 7, 14, 21, 28, 42 and 56 with the percentage of affected body surface calculated and live body weights recorded for each animal on days 4, 28 and 42. The pour-on formulation of moxidectin yielded excellent efficacy as no live mites were found in treated animals at 14, 21, 28, 42 and 56 days PT, except in one animal from which one adult mite was collected on day 42. Clinical indices showed a regular decrease in the affected body surface area. All untreated animals but one remained positive until day 28 and their clinical condition worsened rapidly. In trial 2, two experimental groups of cattle naturally infested with D. bOvis and L. vituli were selected. Group 1 remained as untreated controls whereas Group 2 individuals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg-1 bw. Efficacy was assessed by identifying and counting lice on eight 15 cm hair partings at predefined anatomical sites on days 0, 14, 28 and 42. On the basis of animals cured and lice count reduction, efficacies were 100% on day 14 and from then onwards for both species. In trial 3, 24 animals naturally infested with C. bOvis were divided into three experimental groups comprising eight (Group I), seven (Group 2) and nine animals (Group 3). Group 1 was the untreated control group whereas Groups 2 and 3 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.25 mg and 0.5 mg kg-1 bw, respectively. Efficacy was assessed as in trial 1. Skin scrapings were collected on days -3, 7, 14, 28, 42 and 56 PT. A clinical index was calculated for each animal on days 0, 28 and 56 whereas body weights were recorded on days 0 and 56. At 0.25 mg kg-1 bw, the efficacy of moxidectin cattle pour-on against C. bOvis was incomplete. In contrast, at a dose of 0.5 mg kg-1 bw, moxidectin cattle pour-on was fully effective and by day 14 PT all animals were negative for C. bOvis and remained so until the end of the trial. No side effects were observed during these three trials. These results indicate that at a dose of 0.5 mg kg-1 bw, the pour-on formulation of moxidectin is highly effective against C. bOvis, D. bOvis, L. vituli and P. Ovis.
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Field Efficacy of Moxidectin 0.5% Pour-on against Chorioptes BOvis, Damalinia BOvis, Linognathus Vituli and Psoroptes Ovis in Naturally Infected Cattle
Veterinary parasitology, 1996Co-Authors: Bertrand Losson, J. F. LonneuxAbstract:Abstract Field efficacy of a pour-on formulation of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bOvis, Damalinia bOvis, Linognathus vituli and Psoreptes Ovis. In trial 1, two experimental groups of cattle naturally infested with P. Ovis were formed. Group 1 animals remained as untreated controls whereas Group 2 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg−1 bw. Efficacy was assessed by (a) taking skin samples from each animal on days −4, 7, 14, 21, 28, 42 and 56 post treatment (PT) and observing the numbers of viable P. Ovis mites and (b) clinical examination of animals on days 7, 14, 21, 28, 42 and 56 with the percentage of affected body surface calculated and live body weights recorded for each animal on days 4, 28 and 42. The pour-on formulation of moxidectin yielded excellent efficacy as no live mites were found in treated animals at 14, 21, 28, 42 and 56 days PT, except in one animal from which one adult mite was collected on day 42. Clinical indices showed a regular decrease in the affected body surface area. All untreated animals but one remained positive until day 28 and their clinical condition worsened rapidly. In trial 2, two experimental groups of cattle naturally infested with D. bOvis and L. vituli were selected. Group 1 remained as untreated controls whereas Group 2 individuals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg−1 bw. Efficacy was assessed by identifying and counting lice on eight 15 cm hair partings at predefined anatomical sites on days 0, 14, 28 and 42. On the basis of animals cured and lice count reduction, efficacies were 100% on day 14 and from then onwards for both species. In trial 3, 24 animals naturally infested with C. bOvis were divided into three experimental groups comprising eight (Group 1), seven (Group 2) and nine animals (Group 3). Group 1 was the untreated control group whereas Groups 2 and 3 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.25 mg and 0.5 mg kg−1 bw, respectively. Efficacy was assessed as in trial 1. Skin scrapings were collected on days −3, 7, 14, 28, 42 and 56 PT. A clinical index was calculated for each animal on days 0, 28 and 56 whereas body weights were recorded on days 0 and 56. At 0.25 mg kg−1 bw, the efficacy of moxidectin cattle pour-on against C. bOvis was incomplete. In contrast, at a dose of 0.5 mg kg−1 bw, moxidectin cattle pour-on was fully effective and by day 14 PT all animals were negative for C. bOvis and remained so until the end of the trial. No side effects were observed during these three trials. These results indicate that a dose of 0.5 mg kg−1 bw, the pour-on formulation of moxidectin is highly effective against C. bOvis, D. bOvis, L. vituli and P. Ovis.
Bertrand Losson - One of the best experts on this subject based on the ideXlab platform.
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field efficacy of moxidectin 0 5 pour on against chorioptes bOvis damalinia bOvis linognathus vituli and psoroptes Ovis in naturally infected cattle
Veterinary Parasitology, 1996Co-Authors: Bertrand Losson, J. F. LonneuxAbstract:Field efficacy of a pour-on formulation of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bOvis, Damalinia bOvis, Linognathus vituli and Psoroptes Ovis. In trial 1, two experimental groups of cattle naturally infested with P. Ovis were formed. Group 1 animals remained as untreated controls whereas Group 2 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg-1 bw. Efficacy was assessed by (a) taking skin samples from each animal on days -4, 7, 14, 21, 28, 42 and 56 post treatment (PT) and observing the numbers of viable P. Ovis mites and (b) clinical examination of animals on days 7, 14, 21, 28, 42 and 56 with the percentage of affected body surface calculated and live body weights recorded for each animal on days 4, 28 and 42. The pour-on formulation of moxidectin yielded excellent efficacy as no live mites were found in treated animals at 14, 21, 28, 42 and 56 days PT, except in one animal from which one adult mite was collected on day 42. Clinical indices showed a regular decrease in the affected body surface area. All untreated animals but one remained positive until day 28 and their clinical condition worsened rapidly. In trial 2, two experimental groups of cattle naturally infested with D. bOvis and L. vituli were selected. Group 1 remained as untreated controls whereas Group 2 individuals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg-1 bw. Efficacy was assessed by identifying and counting lice on eight 15 cm hair partings at predefined anatomical sites on days 0, 14, 28 and 42. On the basis of animals cured and lice count reduction, efficacies were 100% on day 14 and from then onwards for both species. In trial 3, 24 animals naturally infested with C. bOvis were divided into three experimental groups comprising eight (Group I), seven (Group 2) and nine animals (Group 3). Group 1 was the untreated control group whereas Groups 2 and 3 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.25 mg and 0.5 mg kg-1 bw, respectively. Efficacy was assessed as in trial 1. Skin scrapings were collected on days -3, 7, 14, 28, 42 and 56 PT. A clinical index was calculated for each animal on days 0, 28 and 56 whereas body weights were recorded on days 0 and 56. At 0.25 mg kg-1 bw, the efficacy of moxidectin cattle pour-on against C. bOvis was incomplete. In contrast, at a dose of 0.5 mg kg-1 bw, moxidectin cattle pour-on was fully effective and by day 14 PT all animals were negative for C. bOvis and remained so until the end of the trial. No side effects were observed during these three trials. These results indicate that at a dose of 0.5 mg kg-1 bw, the pour-on formulation of moxidectin is highly effective against C. bOvis, D. bOvis, L. vituli and P. Ovis.
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Field Efficacy of Moxidectin 0.5% Pour-on against Chorioptes BOvis, Damalinia BOvis, Linognathus Vituli and Psoroptes Ovis in Naturally Infected Cattle
Veterinary parasitology, 1996Co-Authors: Bertrand Losson, J. F. LonneuxAbstract:Abstract Field efficacy of a pour-on formulation of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bOvis, Damalinia bOvis, Linognathus vituli and Psoreptes Ovis. In trial 1, two experimental groups of cattle naturally infested with P. Ovis were formed. Group 1 animals remained as untreated controls whereas Group 2 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg−1 bw. Efficacy was assessed by (a) taking skin samples from each animal on days −4, 7, 14, 21, 28, 42 and 56 post treatment (PT) and observing the numbers of viable P. Ovis mites and (b) clinical examination of animals on days 7, 14, 21, 28, 42 and 56 with the percentage of affected body surface calculated and live body weights recorded for each animal on days 4, 28 and 42. The pour-on formulation of moxidectin yielded excellent efficacy as no live mites were found in treated animals at 14, 21, 28, 42 and 56 days PT, except in one animal from which one adult mite was collected on day 42. Clinical indices showed a regular decrease in the affected body surface area. All untreated animals but one remained positive until day 28 and their clinical condition worsened rapidly. In trial 2, two experimental groups of cattle naturally infested with D. bOvis and L. vituli were selected. Group 1 remained as untreated controls whereas Group 2 individuals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.5 mg kg−1 bw. Efficacy was assessed by identifying and counting lice on eight 15 cm hair partings at predefined anatomical sites on days 0, 14, 28 and 42. On the basis of animals cured and lice count reduction, efficacies were 100% on day 14 and from then onwards for both species. In trial 3, 24 animals naturally infested with C. bOvis were divided into three experimental groups comprising eight (Group 1), seven (Group 2) and nine animals (Group 3). Group 1 was the untreated control group whereas Groups 2 and 3 animals were treated on day 0 with 0.5% moxidectin cattle pour-on at a dose of 0.25 mg and 0.5 mg kg−1 bw, respectively. Efficacy was assessed as in trial 1. Skin scrapings were collected on days −3, 7, 14, 28, 42 and 56 PT. A clinical index was calculated for each animal on days 0, 28 and 56 whereas body weights were recorded on days 0 and 56. At 0.25 mg kg−1 bw, the efficacy of moxidectin cattle pour-on against C. bOvis was incomplete. In contrast, at a dose of 0.5 mg kg−1 bw, moxidectin cattle pour-on was fully effective and by day 14 PT all animals were negative for C. bOvis and remained so until the end of the trial. No side effects were observed during these three trials. These results indicate that a dose of 0.5 mg kg−1 bw, the pour-on formulation of moxidectin is highly effective against C. bOvis, D. bOvis, L. vituli and P. Ovis.
Edison Rogerio Cansi - One of the best experts on this subject based on the ideXlab platform.
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Ovis aries artiodactyla bovidae e capra hircus artiodactyla bovidae parasitados por oestrus Ovis diptera oestridae no distrito federal brasil
EntomoBrasilis, 2011Co-Authors: Edison Rogerio Cansi, Vanessa Da Silva Mustafa, Mirna Ribeiro Porto, Marcio Botelho De Castro, Jose Renato Junqueira BorgesAbstract:A oestrose e uma miiase obrigatoria e cavitaria de ovinos e caprinos, domesticos e selvagens, causada por larvas da mosca Oestrus Ovis (Linnaeus). Este estudo relata a presenca de O. Ovis na regiao Centro-Oeste do Brasil como parasitas de caprinos e ovinos. Nos obtivemos seis larvas de ovinos e caprinos suspeitos de oestrose em Brasilia. As larvas originaram duas moscas femeas adultas de O. Ovis , apos 20 e 23 dias respectivamente. Este achado esta provavelmente associado a expansao e diversificacao da agricultura no cerrado do planalto central brasileiro. Ovis aries (Artiodactyla: Bovidae) and Capra hircus (Artiodactyla: Bovidae) infected by Oestrus Ovis (Diptera: Oestridae) in the Federal District, Brazil Abstract. The Oestrosis is an obligatory and cavitary myiasis of sheep and goat, wild and domestic, caused by the larvae of Oestrus Ovis (Linnaeus) fly. This study records the presence of O. Ovis in the West Central region of Brazil as parasites of goats and sheep. We obtained six larvae from sheep and goats with suspects of oestrosis in Brasilia (Brazil) originate two females adult of O. Ovis , after 20 and 23 days respectively of pupation. This finding is probably associated with expansion and diversification of farming in the Cerrado of the Brazilian central plateau.
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Ovis aries (Artiodactyla: Bovidae) e Capra hircus (Artiodactyla: Bovidae) parasitados por Oestrus Ovis (Diptera: Oestridae) no Distrito Federal, Brasil
Entomologistas do Brasil, 2011Co-Authors: Edison Rogerio Cansi, Márcio De Castro, Vanessa Mustafa, Mirna Porto, José BorgesAbstract:A oestrose é uma miíase obrigatória e cavitária de ovinos e caprinos, domésticos e selvagens, causada por larvas da mosca Oestrus Ovis (Linnaeus). Este estudo relata a presença de O. Ovis na região Centro-Oeste do Brasil como parasitas de caprinos e ovinos. Nós obtivemos seis larvas de ovinos e caprinos suspeitos de oestrose em Brasília. As larvas originaram duas moscas fêmeas adultas de O. Ovis, após 20 e 23 dias respectivamente. Este achado está provavelmente associado à expansão e diversificação da agricultura no cerrado do planalto central brasileiro. Ovis aries (Artiodactyla: Bovidae) and Capra hircus (Artiodactyla: Bovidae) infected by Oestrus Ovis (Diptera: Oestridae) in the Federal District, Brazil Abstract. The Oestrosis is an obligatory and cavitary myiasis of sheep and goat, wild and domestic, caused by the larvae of Oestrus Ovis (Linnaeus) fly. This study records the presence of O. Ovis in the West Central region of Brazil as parasites of goats and sheep. We obtained six larvae from sheep and goats with suspects of oestrosis in Brasília (Brazil) originate two females adult of O. Ovis, after 20 and 23 days respectively of pupation. This finding is probably associated with expansion and diversification of farming in the Cerrado of the Brazilian central plateau
J C Barbacarretero - One of the best experts on this subject based on the ideXlab platform.
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molecular studies on babesia theileria and hepatozoon in southern europe part ii phylogenetic analysis and evolutionary history
Veterinary Parasitology, 2003Co-Authors: A Criadofornelio, A Martinezmarcos, A Bulingsarana, J C BarbacarreteroAbstract:Following a study on molecular epizootiology of Hepatozoon canis and piroplasmids (Babesia spp. and Theileria spp.) in southern Europe, newly obtained sequences of 18s rRNA gene were used for phylogenetic analysis. Partial sequences were analysed in isolates showing high degree of homology (>99%) with previous GenBank entries: H. canis, B. canis vogeli, B. equi (two isolates, Spain1 and Spain2), T. annulata and Theileria sp. The complete gene sequences were used for B. Ovis and B. bOvis, that showed lower homology (<95%) with rapport to previously reported species or isolates. A first set of phylogenetic trees constructed with partial 18s rRNA sequences showed that most European isolates clustered unambiguously with previously described species, so that minor sequence dissimilarities found are due probably to strain variations. The second set of phylogenetic trees was made using the complete 18s rRNA sequences of 44 species from GenBank and the newly sequenced B. Ovis and B. bOvis. The analysis revealed for the first time a division of piroplasmids in five clades: (1) B. microti group, with B. rodhaini, B. felis, B. leo, B. microti and T. annae (proposed name for the group, without taxonomic value: Archaeopiroplasmids), (2) Western USA Theilerid-like group (proposed name: Prototheilerids), (3) Theileria group, containing all Theileria species from Bovinae (proposed name: Theilerids), (4) A first group of Babesia species including B. canis and B. gibsoni from canids together with B. divergens and B. odocoilei (proposed name: Babesids), (5) A second group composed mainly by Babesia species from ungulates: B. caballi, B. bigemina, B. Ovis, B. bOvis and Babesia sp. from cow (proposed name: Ungulibabesids). The bootstrap support obtained with several analytical procedures for this new dicotomy of Babesiidae was always very high. Taking into account the present phylogenetic analysis and additional paleogeographic, parasitological and zoological evidences, two hypothesis on the origin and evolution of piroplasmids groups are presented.
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molecular studies on babesia theileria and hepatozoon in southern europe part i epizootiological aspects
Veterinary Parasitology, 2003Co-Authors: A Criadofornelio, A Martinezmarcos, A Bulingsarana, J C BarbacarreteroAbstract:Abstract Molecular epizootiology of piroplasmids ( Babesia spp., Theileria spp.) and Hepatozoon canis was studied in mammals from southern Europe (mainly from Spain, but also from Portugal and France). Partial amplification and sequencing of the 18s rRNA gene was used for molecular diagnosis. In some particular cases ( B. Ovis and B. bOvis ) the complete 18s rRNA gene was sequenced. Blood samples were taken from domestic animals showing clinical symptoms: 10 dogs, 10 horses, 10 cows, 9 sheep and 1 goat. In addition, DNA samples were isolated from blood of 12 healthy dogs and from spleen of 10 wild red foxes ( Vulpes vulpes ). The results of the survey were the following: • Piroplasmid infections: Approximately from 50 to 70% of wild or domestic mammals (symptomatic) were infected. • Piroplasmids detected in ruminants were: (1) Cow: B. bOvis , T. annulata and Theileria sp. (type C). (2) Sheep and goat: B. Ovis . • Piroplasmids present in canids were: Babesia canis vogeli , Babesia canis canis , Theileria annae and B. equi . The only piroplasmid found in asymptomatic dogs was B. equi . • Piroplasmids found in horse were: B. equi and B. canis canis . • H. canis infections in canids: H. canis was absent of domestic dog samples, whereas all foxes studied were infected by this protozoa. Genetic analysis showed that most of piroplasmid and Hepatozoon isolates from southern Europe matched unambigously with previously described species, as demonstrated by the high level sequence identity between them, usually between 99 and 100%. Minor differences, usually detected in hypervariable regions of 18s rRNA gene are probably due to strain variations or rare genetic polymorphisms. A possible exception was B. bOvis , which shows a relatively lower degree of homology (94%) with regard to other B. bOvis isolates from several countries. The same is true for B. Ovis , that showed a 94% identity with regard to Babesia sp. from South African cow and a 92% with rapport to B. bOvis from Portugal.
Agueda Castagna De Vargas - One of the best experts on this subject based on the ideXlab platform.
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antigenic characterization of moraxella bOvis moraxella bovoculi and moraxella Ovis strains with potential use in vaccines
Veterinary Microbiology, 2017Co-Authors: Ananda Paula Kowalski, Julia Pires Espindola, Caiane Tasca, Leticia Trevisan Gressler, Claudia Balzan, Joao Antonio Guizzo, Fabricio Rochedo Conceicao, Rafael Frandoloso, Agueda Castagna De VargasAbstract:Abstract Moraxella bOvis is historically known as the primary agent of infectious bovine keratoconjunctivitis (IBK). However, Moraxella bovoculi and Moraxella Ovis are also reported to be involved in the pathogenesis of IBK, therefore, these three species should be included in the development of a new vaccine with a broad-spectrum protection against the disease natural challenge. In this study we investigated the antigenic properties of clinical isolates and reference strains of M. bOvis , M. bovoculi and M. Ovis using a novel in vitro approach for vaccine evaluation based on two techniques, flow cytometry and western blotting (WB). Here, we demonstrated that rabbit antisera produced against reference M. bOvis strain and commercial bacterin showed low number of IgG with capacity to recognize a panel of heterologous strains composed by M. bovoculi and M. Ovis . On the other hand, the antisera generated against two clinical isolates of M. Ovis (Mov2 and Mov3) presented high cross-reactivity levels against all M. Ovis and M. bOvis strains evaluated. Similarly, the antisera against Mbv3 (clinical isolate of M. bovoculi ) had high levels of IgG associated on the surface of all M. bovoculi strains and most of the M. Ovis strains analyzed. The WB analysis demonstrated that Moraxella spp. has multiple immunogenic antigens and most of them are shared between the three species. Based on the cross-reactivity analysis and considering the relative number of IgGs associated on the bacterial surface, we suggest that a multivalent vaccine including Mbv3, Mov2 and Mov3 strains may provide a strong and broad protection against all strains involved in IBK outbreaks.
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phylogenetic analysis and genetic diversity of 3 region of rtxa gene from geographically diverse strains of moraxella bOvis moraxella bovoculi and moraxella Ovis
Veterinary Microbiology, 2015Co-Authors: Luana Davila Farias, Leticia Beatriz Matter, Charles Fernando Capinos Scherer, Felipe Libardoni, Agueda Castagna De VargasAbstract:Abstract The cytotoxin A (MbxA) is one of the main virulence factors of Moraxella bOvis involved in the pathogenesis of infectious bovine keratoconjunctivitis (IBK). Moraxella Ovis and Moraxella bovoculi , suspected to be associated with infectious keratitis in sheep and cattle respectively, also have a gene that encodes the cytotoxin A ( movA and mbvA , respectively). The aim of this study was to determine the molecular sequence of the 3’ region of the cytotoxin gene of Moraxella spp. strains isolated from clinical cases to establish phylogenetic and evolutionary comparisons. PCR amplification, nucleotide sequencing (nt) and amino acid (aa) sequence prediction were performed, followed by the sequences comparison, identity level calculation and selective pressure analysis. The phylogenetic reconstruction based on nt and aa sequences clearly differentiate M. bOvis ( n = 15), M. bovoculi ( n = 11) and M. Ovis ( n = 7) and their respective reference strains. An alignment of 843 nt revealed high similarity within bacterial species ( MbxA = 99.9% nt and aa; MbvA = 99.3% nt and 98.8% aa; MovA = 99.5% nt and 99.3% aa). The similarity of partial sequences (nt 1807–2649) of MbxA in relation to MbvA and MovA ranged from 76.3 to 78.5%; similarity between MbvA and MovA ranged from 95.7 to 97.5%. A negative selection on mbvA and movA sequences was revealed by the molecular evolution analysis. The phylogenetic analysis of movA and mbvA allowed different strains of Moraxella spp. to be grouped according to the period of isolation. Sequence analysis of cytotoxin may provide insights into genetic and evolutionary relationships and into the genetic/molecular basis of Moraxella spp.
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differences in the antimicrobial susceptibility profiles of moraxella bOvis m bovoculi and m Ovis
Brazilian Journal of Microbiology, 2015Co-Authors: Grazieli Maboni, Julia Pires Espindola, Marcelo Luis Schwab, Caiane Tasca, Luciana Pötter, Leticia Trevisan Gressler, Agueda Castagna De VargasAbstract:The aim of this study was to determine the differences in the antimicrobial susceptibility profiles of Moraxella bOvis, M. bovoculi and M. Ovis. Thirty-two strains of Moraxella spp. isolated from cattle and sheep with infectious keratoconjunctivitis were tested via broth microdilution method to determine their susceptibility to ampicillin, cefoperazone, ceftiofur, cloxacillin, enrofloxacin, florfenicol, gentamicin, neomycin, oxytetracycline and penicillin. The results demonstrated that Moraxella spp. strains could be considered sensitive for most of the antimicrobials tested in this study, but differences between the antimicrobial susceptibility profiles of these three Moraxella species were found. M. bOvis might differ from other species due to the higher MIC and MBC values it presented.
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Differences in the antimicrobial susceptibility profiles of Moraxella bOvis, M. bovoculi and M. Ovis
2014Co-Authors: Grazieli Maboni, Julia Pires Espindola, Caiane Tasca, Luciana Pötter, Leticia Trevisan Gressler, Marcelo Schwab, Agueda Castagna De VargasAbstract:The aim of this study was to determine the differences in the antimicrobial susceptibility profiles of Moraxella bOvis, M. bovoculi and M. Ovis. Thirty-two strains of Moraxella spp. isolated from cattle and sheep with infectious keratoconjunctivitis were tested via broth microdilution method to deter-mine their susceptibility to ampicillin, cefoperazone, ceftiofur, cloxacillin, enrofloxacin, florfenicol, gentamicin, neomycin, oxytetracycline and penicillin. The results demonstrated that Moraxella spp. strains could be considered sensitive for most of the antimicrobials tested in this study, but differ-ences between the antimicrobial susceptibility profiles of these three Moraxella species were found. M. bOvis might differ from other species due to the higher MIC and MBC values it presented. Key words: bacterial resistance, broth microdilution, eye disease
