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Anne E Holland - One of the best experts on this subject based on the ideXlab platform.
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Effective delivery of ambulatory Oxygen in interstitial lung disease- a crossover trial
Physiotherapists, 2019Co-Authors: Mariana Hoffman, Nicole S L Goh, Christine F Mcdonald, Ian Glaspole, Tamera J. Corte, Daniel C. Chambers, Magnus Ekstrom, Anne E HollandAbstract:Introduction: Portable Oxygen concentrators(POC) are lighter and easier to manoeuvre than portable Oxygen Cylinders, but their ability to meet Oxygen requirements of interstitial lung disease(ILD) patients is unknown. Aim: To compare the effects of ambulatory Oxygen delivered during exercise using either a POC(Inogen OneG2) or a standard portable Cylinder in individuals with ILD. Methods: This randomised crossover trial included individuals with a confirmed diagnosis of ILD with Oxygenhaemogloblin saturation (SpO2) Results: Ten individuals with ILD (7 male) mean(SD) age 72(7) years, TLCO 46(13)% predicted, and forced vital capacity 70(17)% predicted were recruited. There was no difference in nadir SpO2 between 6MWTs with POC or portable Cylinder 82(3)% vs. 81(6)% respectively (p=0.43). Distance achieved on the 6MWT was significantly greater with POC than portable Cylinder 519.4(98.15) vs. 503.5(88.4) metres (p=0.023), but there was no difference in Borg scores for dyspnoea or leg fatigue at the end of either test (p>0.05). Only two participants (n=8) preferred the use of Oxygen Cylinder over POC during exercise. Conclusion: Oxygen desaturation during exercise in people with ILD is similar when using POC or a portable Cylinder. Greater manoeuvrability of the POC, and patient preference for it, suggest POC may be a more acceptable means of delivering Oxygen for people with ILD.
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portable Oxygen concentrator vs Oxygen Cylinder during walking in ild a randomised crossover trial
European Respiratory Journal, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Anne E Holland, Christine F McdonaldAbstract:Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD) to improve breathlessness and quality of life. Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders. However, their efficacy in patients with ILD has not been assessed. This study aimed to compare the clinical performance of a POC versus a compressed Oxygen Cylinder during 6-minute walk tests (6MWTs) in patients with ILD. Methods: Ten patients with ILD of varying aetiologies with exertional Oxygen desaturation to Results: There was no significant difference in mean nadir Oxygen saturation during 6MWTs between the Inogen One G2 POC and the compressed Oxygen Cylinder (82.3% versus 80.3% respectively, p = 0.14). More participants desaturated to less than 80% during 6MWTs using the compressed Oxygen Cylinder (50%), compared to the POC (20%). Both devices provided equivalent Oxygenation at rest (p = 0.70). There was no significant difference in distances walked using either device (p = 0.52). Five participants preferred the POC while only one preferred the compressed Oxygen Cylinder. Conclusion: Our results suggest that in patients with ILD and exertional desaturation, the Inogen One G2 POC had equivalent clinical performance to the compressed Oxygen Cylinder during walking.
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portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease a randomized crossover trial
Respirology, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to <90% on room air during 6MWT were recruited. Each participant performed two 6MWTs while breathing room air. On a subsequent day, two further 6MWTs were performed, in random order: one breathing Oxygen via a POC (either the Inogen One G2 POC or the EverGo POC at the setting of 6) and one with a compressed Oxygen Cylinder (at 5 L/min). Results There were no significant differences in nadir Oxygen saturation (SpO2 ) during 6MWTs using different portable Oxygen devices (Trial 1: mean SpO2 for Inogen One G2 POC: 82.3 ± 3.5% vs Oxygen Cylinder: 80.3 ± 2.2%, P = 0.14; Trial 2: mean SpO2 for EverGo POC: 85.7 ± 7.7% vs Oxygen Cylinder: 86.1 ± 6.1%, P = 0.79). The mean 6-min walk distances were not significantly different among the three devices. Conclusion The performance of the Inogen One G2 POC and the EverGo POC had comparable performance with that of the compressed Oxygen Cylinder during walking in patients with ILD and exertional desaturation.
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Portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease: A randomized crossover trial
Respirology (Carlton Vic.), 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to
Christine F Mcdonald - One of the best experts on this subject based on the ideXlab platform.
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Effective delivery of ambulatory Oxygen in interstitial lung disease- a crossover trial
Physiotherapists, 2019Co-Authors: Mariana Hoffman, Nicole S L Goh, Christine F Mcdonald, Ian Glaspole, Tamera J. Corte, Daniel C. Chambers, Magnus Ekstrom, Anne E HollandAbstract:Introduction: Portable Oxygen concentrators(POC) are lighter and easier to manoeuvre than portable Oxygen Cylinders, but their ability to meet Oxygen requirements of interstitial lung disease(ILD) patients is unknown. Aim: To compare the effects of ambulatory Oxygen delivered during exercise using either a POC(Inogen OneG2) or a standard portable Cylinder in individuals with ILD. Methods: This randomised crossover trial included individuals with a confirmed diagnosis of ILD with Oxygenhaemogloblin saturation (SpO2) Results: Ten individuals with ILD (7 male) mean(SD) age 72(7) years, TLCO 46(13)% predicted, and forced vital capacity 70(17)% predicted were recruited. There was no difference in nadir SpO2 between 6MWTs with POC or portable Cylinder 82(3)% vs. 81(6)% respectively (p=0.43). Distance achieved on the 6MWT was significantly greater with POC than portable Cylinder 519.4(98.15) vs. 503.5(88.4) metres (p=0.023), but there was no difference in Borg scores for dyspnoea or leg fatigue at the end of either test (p>0.05). Only two participants (n=8) preferred the use of Oxygen Cylinder over POC during exercise. Conclusion: Oxygen desaturation during exercise in people with ILD is similar when using POC or a portable Cylinder. Greater manoeuvrability of the POC, and patient preference for it, suggest POC may be a more acceptable means of delivering Oxygen for people with ILD.
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portable Oxygen concentrator vs Oxygen Cylinder during walking in ild a randomised crossover trial
European Respiratory Journal, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Anne E Holland, Christine F McdonaldAbstract:Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD) to improve breathlessness and quality of life. Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders. However, their efficacy in patients with ILD has not been assessed. This study aimed to compare the clinical performance of a POC versus a compressed Oxygen Cylinder during 6-minute walk tests (6MWTs) in patients with ILD. Methods: Ten patients with ILD of varying aetiologies with exertional Oxygen desaturation to Results: There was no significant difference in mean nadir Oxygen saturation during 6MWTs between the Inogen One G2 POC and the compressed Oxygen Cylinder (82.3% versus 80.3% respectively, p = 0.14). More participants desaturated to less than 80% during 6MWTs using the compressed Oxygen Cylinder (50%), compared to the POC (20%). Both devices provided equivalent Oxygenation at rest (p = 0.70). There was no significant difference in distances walked using either device (p = 0.52). Five participants preferred the POC while only one preferred the compressed Oxygen Cylinder. Conclusion: Our results suggest that in patients with ILD and exertional desaturation, the Inogen One G2 POC had equivalent clinical performance to the compressed Oxygen Cylinder during walking.
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portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease a randomized crossover trial
Respirology, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to <90% on room air during 6MWT were recruited. Each participant performed two 6MWTs while breathing room air. On a subsequent day, two further 6MWTs were performed, in random order: one breathing Oxygen via a POC (either the Inogen One G2 POC or the EverGo POC at the setting of 6) and one with a compressed Oxygen Cylinder (at 5 L/min). Results There were no significant differences in nadir Oxygen saturation (SpO2 ) during 6MWTs using different portable Oxygen devices (Trial 1: mean SpO2 for Inogen One G2 POC: 82.3 ± 3.5% vs Oxygen Cylinder: 80.3 ± 2.2%, P = 0.14; Trial 2: mean SpO2 for EverGo POC: 85.7 ± 7.7% vs Oxygen Cylinder: 86.1 ± 6.1%, P = 0.79). The mean 6-min walk distances were not significantly different among the three devices. Conclusion The performance of the Inogen One G2 POC and the EverGo POC had comparable performance with that of the compressed Oxygen Cylinder during walking in patients with ILD and exertional desaturation.
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Portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease: A randomized crossover trial
Respirology (Carlton Vic.), 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to
Yet H Khor - One of the best experts on this subject based on the ideXlab platform.
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portable Oxygen concentrator vs Oxygen Cylinder during walking in ild a randomised crossover trial
European Respiratory Journal, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Anne E Holland, Christine F McdonaldAbstract:Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD) to improve breathlessness and quality of life. Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders. However, their efficacy in patients with ILD has not been assessed. This study aimed to compare the clinical performance of a POC versus a compressed Oxygen Cylinder during 6-minute walk tests (6MWTs) in patients with ILD. Methods: Ten patients with ILD of varying aetiologies with exertional Oxygen desaturation to Results: There was no significant difference in mean nadir Oxygen saturation during 6MWTs between the Inogen One G2 POC and the compressed Oxygen Cylinder (82.3% versus 80.3% respectively, p = 0.14). More participants desaturated to less than 80% during 6MWTs using the compressed Oxygen Cylinder (50%), compared to the POC (20%). Both devices provided equivalent Oxygenation at rest (p = 0.70). There was no significant difference in distances walked using either device (p = 0.52). Five participants preferred the POC while only one preferred the compressed Oxygen Cylinder. Conclusion: Our results suggest that in patients with ILD and exertional desaturation, the Inogen One G2 POC had equivalent clinical performance to the compressed Oxygen Cylinder during walking.
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portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease a randomized crossover trial
Respirology, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to <90% on room air during 6MWT were recruited. Each participant performed two 6MWTs while breathing room air. On a subsequent day, two further 6MWTs were performed, in random order: one breathing Oxygen via a POC (either the Inogen One G2 POC or the EverGo POC at the setting of 6) and one with a compressed Oxygen Cylinder (at 5 L/min). Results There were no significant differences in nadir Oxygen saturation (SpO2 ) during 6MWTs using different portable Oxygen devices (Trial 1: mean SpO2 for Inogen One G2 POC: 82.3 ± 3.5% vs Oxygen Cylinder: 80.3 ± 2.2%, P = 0.14; Trial 2: mean SpO2 for EverGo POC: 85.7 ± 7.7% vs Oxygen Cylinder: 86.1 ± 6.1%, P = 0.79). The mean 6-min walk distances were not significantly different among the three devices. Conclusion The performance of the Inogen One G2 POC and the EverGo POC had comparable performance with that of the compressed Oxygen Cylinder during walking in patients with ILD and exertional desaturation.
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Portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease: A randomized crossover trial
Respirology (Carlton Vic.), 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to
Nicole S L Goh - One of the best experts on this subject based on the ideXlab platform.
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Effective delivery of ambulatory Oxygen in interstitial lung disease- a crossover trial
Physiotherapists, 2019Co-Authors: Mariana Hoffman, Nicole S L Goh, Christine F Mcdonald, Ian Glaspole, Tamera J. Corte, Daniel C. Chambers, Magnus Ekstrom, Anne E HollandAbstract:Introduction: Portable Oxygen concentrators(POC) are lighter and easier to manoeuvre than portable Oxygen Cylinders, but their ability to meet Oxygen requirements of interstitial lung disease(ILD) patients is unknown. Aim: To compare the effects of ambulatory Oxygen delivered during exercise using either a POC(Inogen OneG2) or a standard portable Cylinder in individuals with ILD. Methods: This randomised crossover trial included individuals with a confirmed diagnosis of ILD with Oxygenhaemogloblin saturation (SpO2) Results: Ten individuals with ILD (7 male) mean(SD) age 72(7) years, TLCO 46(13)% predicted, and forced vital capacity 70(17)% predicted were recruited. There was no difference in nadir SpO2 between 6MWTs with POC or portable Cylinder 82(3)% vs. 81(6)% respectively (p=0.43). Distance achieved on the 6MWT was significantly greater with POC than portable Cylinder 519.4(98.15) vs. 503.5(88.4) metres (p=0.023), but there was no difference in Borg scores for dyspnoea or leg fatigue at the end of either test (p>0.05). Only two participants (n=8) preferred the use of Oxygen Cylinder over POC during exercise. Conclusion: Oxygen desaturation during exercise in people with ILD is similar when using POC or a portable Cylinder. Greater manoeuvrability of the POC, and patient preference for it, suggest POC may be a more acceptable means of delivering Oxygen for people with ILD.
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portable Oxygen concentrator vs Oxygen Cylinder during walking in ild a randomised crossover trial
European Respiratory Journal, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Anne E Holland, Christine F McdonaldAbstract:Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD) to improve breathlessness and quality of life. Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders. However, their efficacy in patients with ILD has not been assessed. This study aimed to compare the clinical performance of a POC versus a compressed Oxygen Cylinder during 6-minute walk tests (6MWTs) in patients with ILD. Methods: Ten patients with ILD of varying aetiologies with exertional Oxygen desaturation to Results: There was no significant difference in mean nadir Oxygen saturation during 6MWTs between the Inogen One G2 POC and the compressed Oxygen Cylinder (82.3% versus 80.3% respectively, p = 0.14). More participants desaturated to less than 80% during 6MWTs using the compressed Oxygen Cylinder (50%), compared to the POC (20%). Both devices provided equivalent Oxygenation at rest (p = 0.70). There was no significant difference in distances walked using either device (p = 0.52). Five participants preferred the POC while only one preferred the compressed Oxygen Cylinder. Conclusion: Our results suggest that in patients with ILD and exertional desaturation, the Inogen One G2 POC had equivalent clinical performance to the compressed Oxygen Cylinder during walking.
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portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease a randomized crossover trial
Respirology, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to <90% on room air during 6MWT were recruited. Each participant performed two 6MWTs while breathing room air. On a subsequent day, two further 6MWTs were performed, in random order: one breathing Oxygen via a POC (either the Inogen One G2 POC or the EverGo POC at the setting of 6) and one with a compressed Oxygen Cylinder (at 5 L/min). Results There were no significant differences in nadir Oxygen saturation (SpO2 ) during 6MWTs using different portable Oxygen devices (Trial 1: mean SpO2 for Inogen One G2 POC: 82.3 ± 3.5% vs Oxygen Cylinder: 80.3 ± 2.2%, P = 0.14; Trial 2: mean SpO2 for EverGo POC: 85.7 ± 7.7% vs Oxygen Cylinder: 86.1 ± 6.1%, P = 0.79). The mean 6-min walk distances were not significantly different among the three devices. Conclusion The performance of the Inogen One G2 POC and the EverGo POC had comparable performance with that of the compressed Oxygen Cylinder during walking in patients with ILD and exertional desaturation.
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Portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease: A randomized crossover trial
Respirology (Carlton Vic.), 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to
Ian Glaspole - One of the best experts on this subject based on the ideXlab platform.
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Effective delivery of ambulatory Oxygen in interstitial lung disease- a crossover trial
Physiotherapists, 2019Co-Authors: Mariana Hoffman, Nicole S L Goh, Christine F Mcdonald, Ian Glaspole, Tamera J. Corte, Daniel C. Chambers, Magnus Ekstrom, Anne E HollandAbstract:Introduction: Portable Oxygen concentrators(POC) are lighter and easier to manoeuvre than portable Oxygen Cylinders, but their ability to meet Oxygen requirements of interstitial lung disease(ILD) patients is unknown. Aim: To compare the effects of ambulatory Oxygen delivered during exercise using either a POC(Inogen OneG2) or a standard portable Cylinder in individuals with ILD. Methods: This randomised crossover trial included individuals with a confirmed diagnosis of ILD with Oxygenhaemogloblin saturation (SpO2) Results: Ten individuals with ILD (7 male) mean(SD) age 72(7) years, TLCO 46(13)% predicted, and forced vital capacity 70(17)% predicted were recruited. There was no difference in nadir SpO2 between 6MWTs with POC or portable Cylinder 82(3)% vs. 81(6)% respectively (p=0.43). Distance achieved on the 6MWT was significantly greater with POC than portable Cylinder 519.4(98.15) vs. 503.5(88.4) metres (p=0.023), but there was no difference in Borg scores for dyspnoea or leg fatigue at the end of either test (p>0.05). Only two participants (n=8) preferred the use of Oxygen Cylinder over POC during exercise. Conclusion: Oxygen desaturation during exercise in people with ILD is similar when using POC or a portable Cylinder. Greater manoeuvrability of the POC, and patient preference for it, suggest POC may be a more acceptable means of delivering Oxygen for people with ILD.
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portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease a randomized crossover trial
Respirology, 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to <90% on room air during 6MWT were recruited. Each participant performed two 6MWTs while breathing room air. On a subsequent day, two further 6MWTs were performed, in random order: one breathing Oxygen via a POC (either the Inogen One G2 POC or the EverGo POC at the setting of 6) and one with a compressed Oxygen Cylinder (at 5 L/min). Results There were no significant differences in nadir Oxygen saturation (SpO2 ) during 6MWTs using different portable Oxygen devices (Trial 1: mean SpO2 for Inogen One G2 POC: 82.3 ± 3.5% vs Oxygen Cylinder: 80.3 ± 2.2%, P = 0.14; Trial 2: mean SpO2 for EverGo POC: 85.7 ± 7.7% vs Oxygen Cylinder: 86.1 ± 6.1%, P = 0.79). The mean 6-min walk distances were not significantly different among the three devices. Conclusion The performance of the Inogen One G2 POC and the EverGo POC had comparable performance with that of the compressed Oxygen Cylinder during walking in patients with ILD and exertional desaturation.
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Portable Oxygen concentrators versus Oxygen Cylinder during walking in interstitial lung disease: A randomized crossover trial
Respirology (Carlton Vic.), 2017Co-Authors: Yet H Khor, Nicole S L Goh, Christine F Mcdonald, Anita Hazard, Karen Symons, Glen P Westall, Ian Glaspole, Anne E HollandAbstract:Background and objective Ambulatory Oxygen therapy is often provided to patients with interstitial lung disease (ILD). Lightweight portable Oxygen concentrators (POCs) provide an alternative to traditional portable systems such as compressed Oxygen Cylinders; however, their efficacy in patients with ILD has not been assessed. This study aimed to evaluate the clinical performance of three ambulatory Oxygen systems (two different POCs and a compressed Oxygen Cylinder) during 6-min walk tests (6MWTs) in patients with ILD and exertional desaturation. Methods A total of 20 participants with ILD of varying aetiologies who demonstrated exertional desaturation to
