The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform
Edward M Weaver - One of the best experts on this subject based on the ideXlab platform.
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association of Palatine Tonsil size and obstructive sleep apnea in adults
Laryngoscope, 2018Co-Authors: Sebastian M Jara, Edward M WeaverAbstract:OBJECTIVE The relationship between Palatine Tonsil (PT) size and obstructive sleep apnea (OSA) has not been well established in adults. The purpose of this study was to test the association between PT grade, PT volume, and OSA severity in U.S. adult patients. STUDY DESIGN Cross-sectional study of all patients (age ≥ 18 years) who underwent pharyngeal surgery for OSA that included Palatine Tonsillectomy with Tonsil volume measurement from January 2011 to June 2016. METHODS Medical records were reviewed for PT grade (measured on clinical exam by the Brodsky Tonsil grading scale), PT volume (measured intraoperatively by water displacement), and apnea-hypopnea index (AHI). Associations were evaluated with multivariate linear regression adjusting for age, sex, body mass index (BMI), smoking status, lingual Tonsil volume (AHI models only), and multilevel surgery aside from lingual Tonsillectomy (PT volume vs. AHI model only). RESULTS The cohort (N = 83) was middle-aged (mean age 43 ± 12 years), predominantly male (61%), obese (mean BMI 33 ± 7 kg/m2 ), and had severe OSA (mean AHI 32 ± 28). After adjustment for confounders, PT grade was strongly associated with PT volume (beta = 1.8, 95% confidence interval [CI]: [1.0, 2.6], P < 0.001) and with AHI (beta = 13.5, 95% CI: [3.5, 23.6], P = 0.01); PT volume was not associated with AHI (beta = -0.2, 95% CI: [-2.2, 1.9], P = 0.89). CONCLUSION In contrast to past studies, subjective PT grade (vs. objective PT volume) was more strongly associated with AHI. These data suggest the space that the Tonsils occupy within the oropharyngeal airway, instead of their actual measured volume, may be more predictive of OSA severity in a cohort of U.S. adult patients. LEVEL OF EVIDENCE 2c. Laryngoscope, 128:1002-1006, 2018.
Jong Hwan Wang - One of the best experts on this subject based on the ideXlab platform.
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Palatine Tonsil size in obese overweight and normal weight children with sleep disordered breathing
Otolaryngology-Head and Neck Surgery, 2010Co-Authors: Jong Hwan Wang, Yoosam Chung, Young Wook Cho, Doyoun Kim, Ji Seon Bae, Myung Joo ShimAbstract:Abstract Objective To assess Palatine Tonsil size relative to degree of obesity in children with sleep-disordered breathing (SDB). Study Design Case-control study. Setting Tertiary care rhinology clinic. Subjects and Methods We compared the subjective and objective Tonsil size, including Tonsil height (TH), Tonsil width (TW), Tonsil thickness (TT), Tonsil weight (TWt), and Tonsil volume (TV), in 26 obese children and 26 age- and gender-matched control children with SDB, and in 29 overweight children and 29 matched controls with SDB. Results Despite similar subjective Tonsil size in obese and control children, the objective Tonsil size, including TH, TW, TT, and TWt, was larger in obese than in control children, and the mean TV was significantly greater in obese than in control children with SDB (8.53 ± 3.30 mL vs 6.90 ± 2.05 mL; 95% confidence interval [CI] of the difference 0.03-3.25; P = 0.019). In contrast, mean TV (7.38 ± 3.43 mL vs 7.65 ± 1.97 mL; 95% CI −1.92 to 1.37; P = 0.320) as well as the other parameters of objective Palatine Tonsil size, including TH, TW, TT, and TWt, did not differ significantly between overweight children and controls. Conclusion Obese children with SDB had larger Palatine Tonsils than did normal-weight children with SDB. This finding suggests that larger Palatine Tonsils may have a greater effect on upper airway obstruction in obese than in normal-weight children with SDB.
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Palatine Tonsil size and its correlation with subjective Tonsil size in patients with sleep disordered breathing
Otolaryngology-Head and Neck Surgery, 2009Co-Authors: Jong Hwan Wang, Yoosam Chung, Yong Ju Jang, Bongjae LeeAbstract:Abstract Objective To investigate the correlation of subjective Tonsil size with real Palatine Tonsil size and to compare the differences of each parameter according to subjective Tonsil size and between children and adults. Study Design Prospective evaluation of subjective Tonsil size (0-4+) and real Palatine Tonsil size, including Tonsil height (TH), Tonsil width (TW), Tonsil thickness (TT), total Tonsil volume (TTV), and embedded Tonsil volume (ETV) within the Tonsillar fossa. Setting Tertiary-care rhinologic clinic. Subjects and Methods We measured TH, TW, TT, TTV, and ETV in 277 children and 63 adults with sleep-disordered breathing (SDB). Results In both children and adults, subjective Tonsil size was significantly correlated with TTV, TH, TW, and TT (correlation coefficients 0.199-0.427 for children and 0.462-0.551 for adults). In children, TTV increased in proportion to subjective Tonsil size, but about 45 percent and 34 percent of Tonsils markedly deviated from the mean value of their TTV in size 2 and 3 groups, respectively. In adults, TTV of subjective Tonsil size 3 and 4 groups was significantly larger than that of size 1 and 2 groups. Conclusions Real Palatine Tonsil size correlated with subjective Tonsil size in both children and adults with SDB. Although there is a statistical correlation in children between TTV and subjective Tonsil size, there is significant discordance in size 2 and 3 groups, thus greatly limiting the value of subjective Tonsil size assessment in the majority of children. However, adult subjective Tonsil size may reflect real Palatine Tonsil size and may help predict it preoperatively.
Maria Aparecida Custodio Domingues - One of the best experts on this subject based on the ideXlab platform.
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solitary fibrous tumor with atypical histological features occurring in the Palatine Tonsil an uncommon neoplasm in an uncommon site
Journal of Oral Pathology & Medicine, 2006Co-Authors: Ricardo Silvestre Macarenco, Carlos E Bacchi, Maria Aparecida Custodio DominguesAbstract:: Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm that usually arises in the pleura. Although this tumor has been described in other sites, including the head and neck area, in the oropharynx it is extremely rare. We report the first case of a SFT arising from the Palatine Tonsil of a 62-year-old man. The tumor consisted of spindle-shaped cells distributed in a haphazard pattern and presented atypical histological features such as hypercellular areas and high mitotic count. Immunohistochemical studies showed strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin, S-100 protein and cytokeratines were negative. The patient was well without disease 1 year after surgery.
Bongjae Lee - One of the best experts on this subject based on the ideXlab platform.
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Palatine Tonsil size and its correlation with subjective Tonsil size in patients with sleep disordered breathing
Otolaryngology-Head and Neck Surgery, 2009Co-Authors: Jong Hwan Wang, Yoosam Chung, Yong Ju Jang, Bongjae LeeAbstract:Abstract Objective To investigate the correlation of subjective Tonsil size with real Palatine Tonsil size and to compare the differences of each parameter according to subjective Tonsil size and between children and adults. Study Design Prospective evaluation of subjective Tonsil size (0-4+) and real Palatine Tonsil size, including Tonsil height (TH), Tonsil width (TW), Tonsil thickness (TT), total Tonsil volume (TTV), and embedded Tonsil volume (ETV) within the Tonsillar fossa. Setting Tertiary-care rhinologic clinic. Subjects and Methods We measured TH, TW, TT, TTV, and ETV in 277 children and 63 adults with sleep-disordered breathing (SDB). Results In both children and adults, subjective Tonsil size was significantly correlated with TTV, TH, TW, and TT (correlation coefficients 0.199-0.427 for children and 0.462-0.551 for adults). In children, TTV increased in proportion to subjective Tonsil size, but about 45 percent and 34 percent of Tonsils markedly deviated from the mean value of their TTV in size 2 and 3 groups, respectively. In adults, TTV of subjective Tonsil size 3 and 4 groups was significantly larger than that of size 1 and 2 groups. Conclusions Real Palatine Tonsil size correlated with subjective Tonsil size in both children and adults with SDB. Although there is a statistical correlation in children between TTV and subjective Tonsil size, there is significant discordance in size 2 and 3 groups, thus greatly limiting the value of subjective Tonsil size assessment in the majority of children. However, adult subjective Tonsil size may reflect real Palatine Tonsil size and may help predict it preoperatively.
Yoosam Chung - One of the best experts on this subject based on the ideXlab platform.
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Palatine Tonsil size in obese overweight and normal weight children with sleep disordered breathing
Otolaryngology-Head and Neck Surgery, 2010Co-Authors: Jong Hwan Wang, Yoosam Chung, Young Wook Cho, Doyoun Kim, Ji Seon Bae, Myung Joo ShimAbstract:Abstract Objective To assess Palatine Tonsil size relative to degree of obesity in children with sleep-disordered breathing (SDB). Study Design Case-control study. Setting Tertiary care rhinology clinic. Subjects and Methods We compared the subjective and objective Tonsil size, including Tonsil height (TH), Tonsil width (TW), Tonsil thickness (TT), Tonsil weight (TWt), and Tonsil volume (TV), in 26 obese children and 26 age- and gender-matched control children with SDB, and in 29 overweight children and 29 matched controls with SDB. Results Despite similar subjective Tonsil size in obese and control children, the objective Tonsil size, including TH, TW, TT, and TWt, was larger in obese than in control children, and the mean TV was significantly greater in obese than in control children with SDB (8.53 ± 3.30 mL vs 6.90 ± 2.05 mL; 95% confidence interval [CI] of the difference 0.03-3.25; P = 0.019). In contrast, mean TV (7.38 ± 3.43 mL vs 7.65 ± 1.97 mL; 95% CI −1.92 to 1.37; P = 0.320) as well as the other parameters of objective Palatine Tonsil size, including TH, TW, TT, and TWt, did not differ significantly between overweight children and controls. Conclusion Obese children with SDB had larger Palatine Tonsils than did normal-weight children with SDB. This finding suggests that larger Palatine Tonsils may have a greater effect on upper airway obstruction in obese than in normal-weight children with SDB.
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Palatine Tonsil size and its correlation with subjective Tonsil size in patients with sleep disordered breathing
Otolaryngology-Head and Neck Surgery, 2009Co-Authors: Jong Hwan Wang, Yoosam Chung, Yong Ju Jang, Bongjae LeeAbstract:Abstract Objective To investigate the correlation of subjective Tonsil size with real Palatine Tonsil size and to compare the differences of each parameter according to subjective Tonsil size and between children and adults. Study Design Prospective evaluation of subjective Tonsil size (0-4+) and real Palatine Tonsil size, including Tonsil height (TH), Tonsil width (TW), Tonsil thickness (TT), total Tonsil volume (TTV), and embedded Tonsil volume (ETV) within the Tonsillar fossa. Setting Tertiary-care rhinologic clinic. Subjects and Methods We measured TH, TW, TT, TTV, and ETV in 277 children and 63 adults with sleep-disordered breathing (SDB). Results In both children and adults, subjective Tonsil size was significantly correlated with TTV, TH, TW, and TT (correlation coefficients 0.199-0.427 for children and 0.462-0.551 for adults). In children, TTV increased in proportion to subjective Tonsil size, but about 45 percent and 34 percent of Tonsils markedly deviated from the mean value of their TTV in size 2 and 3 groups, respectively. In adults, TTV of subjective Tonsil size 3 and 4 groups was significantly larger than that of size 1 and 2 groups. Conclusions Real Palatine Tonsil size correlated with subjective Tonsil size in both children and adults with SDB. Although there is a statistical correlation in children between TTV and subjective Tonsil size, there is significant discordance in size 2 and 3 groups, thus greatly limiting the value of subjective Tonsil size assessment in the majority of children. However, adult subjective Tonsil size may reflect real Palatine Tonsil size and may help predict it preoperatively.